Human aortic smooth muscle cell-derived exosomal miR-221/222 inhibits autophagy via a PTEN/Akt signaling pathway in human umbilical vein endothelial cells

Biochemical and Biophysical Research Communications

Volumn 479, Issue 2, 2016, Pages 343-350

  Li, Luocheng ^a   Wang, Zhiwei ^a   Hu, Xiaoping ^a   Wan, Ting ^a   Wu, Hongbing ^a   Jiang, Wanli ^a   Hu, Rui ^a  

^a RENMIN HOSPITAL OF WUHAN UNIVERSITY   (China)

Author keywords

Akt; Autophagy; Exosomes; miR 221 222; PTEN

Indexed keywords

AUTOPHAGY PROTEIN 5; BECLIN 1; MICRORNA 221; MICRORNA 222; PHOSPHATASE; PROTEIN; PROTEIN KINASE B; SQSTM1 PROTEIN; TENSIN; UNCLASSIFIED DRUG; MICRORNA; MIRN221 MICRORNA, HUMAN; MIRN222 MICRORNA, HUMAN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PTEN PROTEIN, HUMAN;

3' UNTRANSLATED REGION; AORTIC SMOOTH MUSCLE CELL; ARTICLE; AUTOPHAGY; CHROMOSOME DELETION; COCULTURE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; EXOSOME; GENE OVEREXPRESSION; GENE TRANSFER; HUMAN; HUMAN CELL; LUCIFERASE ASSAY; PRIORITY JOURNAL; UMBILICAL VEIN ENDOTHELIAL CELL; AORTA; CELL LINE; CYTOLOGY; METABOLISM; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE CELL; TRANSMISSION ELECTRON MICROSCOPY;

AORTA; AUTOPHAGY; CELL LINE; COCULTURE TECHNIQUES; EXOSOMES; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MICRORNAS; MICROSCOPY, ELECTRON, TRANSMISSION; MYOCYTES, SMOOTH MUSCLE; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; REAL-TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 84989177780     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2016.09.078     Document Type: Article

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