Cell-specific effects of miR-221/222 in vessels: Molecular mechanism and therapeutic application

Journal of Molecular and Cellular Cardiology

Volumn 52, Issue 1, 2012, Pages 245-255

  Liu, Xiaojun ^a   Cheng, Yunhui ^a   Yang, Jian ^a   Xu, Ling ^a   Zhang, Chunxiang ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

Author keywords

Cell specific effects; Endothelial cells; MicroRNAs; Smooth muscle cells; Vascular disease

Indexed keywords

MICRORNA; MICRORNA 221; MICRORNA 222; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CARDIOVASCULAR SYSTEM; CAROTID ARTERY; CELL CULTURE; CELL FUNCTION; CELL MIGRATION; CELL PROLIFERATION; CELL SPECIFICITY; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE TARGETING; IN VIVO STUDY; MALE; MOLECULAR MECHANICS; NONHUMAN; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

ANIMALS; APOPTOSIS; CAROTID ARTERIES; CAROTID ARTERY INJURIES; CELL MOVEMENT; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYCLIN-DEPENDENT KINASE INHIBITOR P57; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMANS; MALE; MICRORNAS; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PROTO-ONCOGENE PROTEINS C-KIT; RATS; TUNICA INTIMA;

RATTUS;

EID: 84155194920     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2011.11.008     Document Type: Article

References (28)

1. Ambros V. MicroRNA pathways in flies and worms: growth, death, fat, stress, and timing. Cell 2003, 113:673-676.
2. Farh K.K., Grimson A., Jan C., Lewis B.P., Johnston W.K., Lim L.P., et al. The widespread impact of mammalian microRNAs on mRNA repression and evolution. Science 2005, 310:1817-1821.
3. Pasquinelli A.E., Hunter S., Bracht J. MicroRNAs: a developing story. Curr Opin Genet Dev 2005, 15:200-205.
4. Bartel D.P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004, 116:281-297.
5. Ambros V. The functions of animal microRNAs. Nature. 2004, 431.
6. Zhang C. Novel functions for small RNA molecules. Curr Opin Mol Ther 2009, 11:541-551.
7. Chan J.A., Krichevsky A.M., Kosik K.S. MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res 2005, 65:6029-6033.
8. Cheng A.M., Byrom M.W., Shelton J., Ford L.P. Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis. Nucleic Acids Res 2005, 33:1290-1297.
9. Liu X., Cheng Y., Zhang S., Lin Y., Yang J., Zhang C. A necessary role of miR-222 and miR-221 in vascular smooth muscle cell proliferation and neointimal hyperplasia. Circ Res 2009, 104:476-487.
10. Poliseno L., Tuccoli A., Mariani L., Evangelista M., Citti L., Woods K., et al. MicroRNAs modulate the angiogenic properties of HUVECs. Blood 2006, 108:3068-3071.
11. Ji R., Cheng Y., Yue J., Yang J., Liu X., Chen H., et al. MicroRNA expression signature and antisense-mediated depletion reveal an essential role of microRNA in vascular neointimal lesion formation. Circ Res 2007, 100:1579-1588.
12. Cheng Y., Liu X., Yang J., Lin Y., Xu D.Z., Lu Q., et al. MicroRNA-145, a novel smooth muscle cell phenotypic marker and modulator, controls vascular neointimal lesion formation. Circ Res 2009, 105:158-166.
13. Zhang C., Yang J., Jennings L.K. Attenuation of neointima formation through the inhibition of DNA repair enzyme PARP-1 in balloon-injured rat carotid artery. Am J Physiol Heart Circ Physiol 2004, 287:H659-H666.
14. Kotha J., Zhang C., Longhurst C.M., Lu Y., Jacobs J., Cheng Y., et al. Functional relevance of tetraspanin CD9 in vascular smooth muscle cell injury phenotypes: a novel target for the prevention of neointimal hyperplasia. Atherosclerosis 2009, 203:377-386.
15. Ashino T., Sudhahar V., Urao N., Oshikawa J., Chen G.F., Wang H., et al. Unexpected role of the copper transporter ATP7A in PDGF-induced vascular smooth muscle cell migration. Circ Res 2010, 107:787-799.
16. Kuehbacher A., Urbich C., Zeiher A.M., Dimmeler S. Role of Dicer and Drosha for endothelial microRNA expression and angiogenesis. Circ Res 2007, 101:59-68.
17. Dentelli P., Rosso A., Orso F., Olgasi C., Taverna D., Brizzi M.F. microRNA-222 controls neovascularization by regulating signal transducer and activator of transcription 5A expression. Arterioscler Thromb Vasc Biol 2010, 30:1562-1568.
18. Lin Y., Liu X., Cheng Y., Yang J., Huo Y., Zhang C. Involvement of microRNAs in hydrogen peroxide-mediated gene regulation and cellular injury response in vascular smooth muscle cells. J Biol Chem 2009, 284:7903-7913.
19. Dong S., Cheng Y., Yang J., Li J., Liu X., Wang X., et al. MicroRNA expression signature and the role of microRNA-21 in the early phase of acute myocardial infarction. J Biol Chem 2009, 284:29514-29525.
20. Chen J.P. Safety and efficacy of the drug-eluting stent: a double-edged sword?. South Med J 2008, 101:123-124.
21. Austin D., Pell J.P., Oldroyd K.G. Drug-eluting stents: a review of current evidence on clinical effectiveness and late complications. Scott Med J 2008, 53:16-24.
22. Flores-Ríos X., Marzoa-Rivas R., Abugattás-de Torres J.P., Piñón-Esteban P., Aldama-López G., Salgado-Fernández J., et al. Late thrombosis of paclitaxel-eluting stents: long-term incidence, clinical consequences, and risk factors in a cohort of 604 patients. Am Heart J 2008, 155:648-653.
23. Agostoni P., Vermeersch P. Bare-metal versus drug-eluting coronary stents. N Engl J Med 2008, 358:2516-2517.
24. Pendyala L., Jabara R., Shinke T., Chronos N., Robinson K., Li J., et al. Drug-eluting stents: present and future. Cardiovasc Hematol Agents Med Chem 2008, 6:105-115.
25. Saia F., Marzocchi A., Serruys P.W. Drug-eluting stents. The third revolution in percutaneous coronary intervention. Ital Heart J 2005, 6:289-03.
26. Davis B.N., Hilyard A.C., Nguyen P.H., Lagna G., Hata A. Induction of microRNA-221 by platelet-derived growth factor signaling is critical for modulation of vascular smooth muscle phenotype. J Biol Chem 2009, 284:3728-3738.
27. Suárez Y., Fernández-Hernando C., Yu J., Gerber S.A., Harrison K.D., Pober J.S., et al. Dicer dependent microRNAs regulate gene expression and functions in human endothelial cells. Circ Res 2007, 100:1164-1173.
28. Zhu N., Zhang D., Chen S., Liu X., Lin L., Huang X., et al. Endothelial enriched microRNAs regulate angiotensin II-induced endothelial inflammation and migration. Atherosclerosis 2011, 215:286-293.