메뉴 건너뛰기




Volumn 68, Issue 10, 2016, Pages 2476-2486

Interleukin-23–Dependent γ/δ T Cells Produce Interleukin-17 and Accumulate in the Enthesis, Aortic Valve, and Ciliary Body in Mice

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; INTERLEUKIN 17; INTERLEUKIN 22; INTERLEUKIN 23; MINICIRCLE DNA; RETINOID RELATED ORPHAN RECEPTOR GAMMA; GREEN FLUORESCENT PROTEIN; IL17A PROTEIN, MOUSE; INTERLEUKIN DERIVATIVE; INTERLEUKIN-22; LYMPHOCYTE ANTIGEN RECEPTOR; RORC PROTEIN, MOUSE;

EID: 84988844036     PISSN: 23265191     EISSN: 23265205     Source Type: Journal    
DOI: 10.1002/art.39732     Document Type: Article
Times cited : (169)

References (50)
  • 1
    • 84918829479 scopus 로고    scopus 로고
    • Prevalence of extra-articular manifestations in patients with ankylosing spondylitis: a systematic review and meta-analysis
    • Stolwijk C, van Tubergen A, Castillo-Ortiz JD, Boonen A. Prevalence of extra-articular manifestations in patients with ankylosing spondylitis: a systematic review and meta-analysis. Ann Rheum Dis 2015;74:65–73.
    • (2015) Ann Rheum Dis , vol.74 , pp. 65-73
    • Stolwijk, C.1    van Tubergen, A.2    Castillo-Ortiz, J.D.3    Boonen, A.4
  • 3
    • 84879691837 scopus 로고    scopus 로고
    • Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci
    • Cortes A, Hadler J, Pointon JP, Robinson PC, Karaderi T, Leo P, et al. Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci. Nat Genet 2013;45:730–8.
    • (2013) Nat Genet , vol.45 , pp. 730-738
    • Cortes, A.1    Hadler, J.2    Pointon, J.P.3    Robinson, P.C.4    Karaderi, T.5    Leo, P.6
  • 4
    • 33846608131 scopus 로고    scopus 로고
    • A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes
    • Cargill M, Schrodi SJ, Chang M, Garcia VE, Brandon R, Callis KP, et al. A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes. Am J Hum Genet 2007;80:273–90.
    • (2007) Am J Hum Genet , vol.80 , pp. 273-290
    • Cargill, M.1    Schrodi, S.J.2    Chang, M.3    Garcia, V.E.4    Brandon, R.5    Callis, K.P.6
  • 5
    • 33845340501 scopus 로고    scopus 로고
    • A genome-wide association study identifies IL23R as an inflammatory bowel disease gene
    • Duerr RH, Taylor KD, Brant SR, Rioux JD, Silverberg MS, Daly MJ, et al. A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science 2006;314:1461–3.
    • (2006) Science , vol.314 , pp. 1461-1463
    • Duerr, R.H.1    Taylor, K.D.2    Brant, S.R.3    Rioux, J.D.4    Silverberg, M.S.5    Daly, M.J.6
  • 6
    • 84933672236 scopus 로고    scopus 로고
    • The IL-23-IL-17 axis in inflammatory arthritis
    • Lubberts E. The IL-23-IL-17 axis in inflammatory arthritis. Nat Rev Rheumatol 2015;11:415–29.
    • (2015) Nat Rev Rheumatol , vol.11 , pp. 415-429
    • Lubberts, E.1
  • 7
    • 69449086287 scopus 로고    scopus 로고
    • HLA–B27 misfolding and the unfolded protein response augment interleukin-23 production and are associated with Th17 activation in transgenic rats
    • DeLay ML, Turner MJ, Klenk EI, Smith JA, Sowders DP, Colbert RA. HLA–B27 misfolding and the unfolded protein response augment interleukin-23 production and are associated with Th17 activation in transgenic rats. Arthritis Rheum 2009;60:2633–43.
    • (2009) Arthritis Rheum , vol.60 , pp. 2633-2643
    • DeLay, M.L.1    Turner, M.J.2    Klenk, E.I.3    Smith, J.A.4    Sowders, D.P.5    Colbert, R.A.6
  • 8
    • 84903907928 scopus 로고    scopus 로고
    • Evidence that autophagy, but not the unfolded protein response, regulates the expression of IL-23 in the gut of patients with ankylosing spondylitis and subclinical gut inflammation
    • Ciccia F, Accardo-Palumbo A, Rizzo A, Guggino G, Raimondo S, Giardina A, et al. Evidence that autophagy, but not the unfolded protein response, regulates the expression of IL-23 in the gut of patients with ankylosing spondylitis and subclinical gut inflammation. Ann Rheum Dis 2014;73:1566–74.
    • (2014) Ann Rheum Dis , vol.73 , pp. 1566-1574
    • Ciccia, F.1    Accardo-Palumbo, A.2    Rizzo, A.3    Guggino, G.4    Raimondo, S.5    Giardina, A.6
  • 9
    • 79954450170 scopus 로고    scopus 로고
    • Increased serum IL-17 and IL-23 in the patient with ankylosing spondylitis
    • Mei Y, Pan F, Gao J, Ge R, Duan Z, Zeng Z, et al. Increased serum IL-17 and IL-23 in the patient with ankylosing spondylitis. Clin Rheumatol 2011;30:269–73.
    • (2011) Clin Rheumatol , vol.30 , pp. 269-273
    • Mei, Y.1    Pan, F.2    Gao, J.3    Ge, R.4    Duan, Z.5    Zeng, Z.6
  • 10
    • 65249152431 scopus 로고    scopus 로고
    • Overexpression of interleukin-23, but not interleukin-17, as an immunologic signature of subclinical intestinal inflammation in ankylosing spondylitis
    • Ciccia F, Bombardieri M, Principato A, Giardina A, Tripodo C, Porcasi R, et al. Overexpression of interleukin-23, but not interleukin-17, as an immunologic signature of subclinical intestinal inflammation in ankylosing spondylitis. Arthritis Rheum 2009;60:955–65.
    • (2009) Arthritis Rheum , vol.60 , pp. 955-965
    • Ciccia, F.1    Bombardieri, M.2    Principato, A.3    Giardina, A.4    Tripodo, C.5    Porcasi, R.6
  • 11
    • 84863697312 scopus 로고    scopus 로고
    • IL-23 induces spondyloarthropathy by acting on ROR-γt+ CD3+CD4−CD8− entheseal resident T cells
    • Sherlock JP, Joyce-Shaikh B, Turner SP, Chao CC, Sathe M, Grein J, et al. IL-23 induces spondyloarthropathy by acting on ROR-γt+ CD3+CD4−CD8− entheseal resident T cells. Nat Med 2012;18:1069–76.
    • (2012) Nat Med , vol.18 , pp. 1069-1076
    • Sherlock, J.P.1    Joyce-Shaikh, B.2    Turner, S.P.3    Chao, C.C.4    Sathe, M.5    Grein, J.6
  • 12
    • 66449133523 scopus 로고    scopus 로고
    • Frequency and phenotype of peripheral blood Th17 cells in ankylosing spondylitis and rheumatoid arthritis
    • Shen H, Goodall JC, Hill Gaston JS. Frequency and phenotype of peripheral blood Th17 cells in ankylosing spondylitis and rheumatoid arthritis. Arthritis Rheum 2009;60:1647–56.
    • (2009) Arthritis Rheum , vol.60 , pp. 1647-1656
    • Shen, H.1    Goodall, J.C.2    Hill Gaston, J.S.3
  • 13
    • 84942582263 scopus 로고    scopus 로고
    • Natural killer cells and γ-δ T cell alterations in enthesitis related arthritis category of juvenile idiopathic arthritis
    • Gaur P, Misra R, Aggarwal A. Natural killer cells and γ-δ T cell alterations in enthesitis related arthritis category of juvenile idiopathic arthritis. Clin Immunol 2015;161:163–9.
    • (2015) Clin Immunol , vol.161 , pp. 163-169
    • Gaur, P.1    Misra, R.2    Aggarwal, A.3
  • 14
    • 0035069607 scopus 로고    scopus 로고
    • Immunohistological study of entheses in spondyloarthropathies: comparison in rheumatoid arthritis and osteoarthritis
    • Laloux L, Voisin MC, Allain J, Martin N, Kerboull L, Chevalier X, et al. Immunohistological study of entheses in spondyloarthropathies: comparison in rheumatoid arthritis and osteoarthritis. Ann Rheum Dis 2001;60:316–21.
    • (2001) Ann Rheum Dis , vol.60 , pp. 316-321
    • Laloux, L.1    Voisin, M.C.2    Allain, J.3    Martin, N.4    Kerboull, L.5    Chevalier, X.6
  • 17
    • 84858644639 scopus 로고    scopus 로고
    • Enrichment of circulating interleukin-17–secreting interleukin-23 receptor–positive γ/δ T cells in patients with active ankylosing spondylitis
    • Kenna TJ, Davidson SI, Duan R, Bradbury LA, McFarlane J, Smith M, et al. Enrichment of circulating interleukin-17–secreting interleukin-23 receptor–positive γ/δ T cells in patients with active ankylosing spondylitis. Arthritis Rheum 2012;64:1420–9.
    • (2012) Arthritis Rheum , vol.64 , pp. 1420-1429
    • Kenna, T.J.1    Davidson, S.I.2    Duan, R.3    Bradbury, L.A.4    McFarlane, J.5    Smith, M.6
  • 19
    • 45149109643 scopus 로고    scopus 로고
    • In vivo equilibrium of proinflammatory IL-17+ and regulatory IL-10+ Foxp3+ RORγt+ T cells
    • Lochner M, Peduto L, Cherrier M, Sawa S, Langa F, Varona R, et al. In vivo equilibrium of proinflammatory IL-17+ and regulatory IL-10+ Foxp3+ RORγt+ T cells. J Exp Med 2008;205:1381–93.
    • (2008) J Exp Med , vol.205 , pp. 1381-1393
    • Lochner, M.1    Peduto, L.2    Cherrier, M.3    Sawa, S.4    Langa, F.5    Varona, R.6
  • 20
    • 68649090645 scopus 로고    scopus 로고
    • Cutting edge: IL-23 receptor gfp reporter mice reveal distinct populations of IL-17–producing cells
    • Awasthi A, Riol-Blanco L, Jager A, Korn T, Pot C, Galileos G, et al. Cutting edge: IL-23 receptor gfp reporter mice reveal distinct populations of IL-17–producing cells. J Immunol 2009;182:5904–8.
    • (2009) J Immunol , vol.182 , pp. 5904-5908
    • Awasthi, A.1    Riol-Blanco, L.2    Jager, A.3    Korn, T.4    Pot, C.5    Galileos, G.6
  • 21
    • 84864325431 scopus 로고    scopus 로고
    • Development of interleukin-17-producing γδ T cells is restricted to a functional embryonic wave
    • Haas JD, Ravens S, Duber S, Sandrock I, Oberdorfer L, Kashani E, et al. Development of interleukin-17-producing γδ T cells is restricted to a functional embryonic wave. Immunity 2012;37:48–59.
    • (2012) Immunity , vol.37 , pp. 48-59
    • Haas, J.D.1    Ravens, S.2    Duber, S.3    Sandrock, I.4    Oberdorfer, L.5    Kashani, E.6
  • 22
    • 73949113499 scopus 로고    scopus 로고
    • Induction of B-cell development in adult mice reveals the ability of bone marrow to produce B-1a cells
    • Duber S, Hafner M, Krey M, Lienenklaus S, Roy B, Hobeika E, et al. Induction of B-cell development in adult mice reveals the ability of bone marrow to produce B-1a cells. Blood 2009;114:4960–7.
    • (2009) Blood , vol.114 , pp. 4960-4967
    • Duber, S.1    Hafner, M.2    Krey, M.3    Lienenklaus, S.4    Roy, B.5    Hobeika, E.6
  • 23
    • 0842282900 scopus 로고    scopus 로고
    • Subset-specific, uniform activation among Vγ6/Vδ1+γδ T cells elicited by inflammation
    • Roark CL, Aydintug MK, Lewis J, Yin X, Lahn M, Hahn YS, et al. Subset-specific, uniform activation among Vγ6/Vδ1+γδ T cells elicited by inflammation. J Leukoc Biol 2004;75:68–75.
    • (2004) J Leukoc Biol , vol.75 , pp. 68-75
    • Roark, C.L.1    Aydintug, M.K.2    Lewis, J.3    Yin, X.4    Lahn, M.5    Hahn, Y.S.6
  • 26
    • 0036582288 scopus 로고    scopus 로고
    • Gammadelta T cells: functional plasticity and heterogeneity
    • Carding SR, Egan PJ. Gammadelta T cells: functional plasticity and heterogeneity. Nat Rev Immunol 2002;2:336–45.
    • (2002) Nat Rev Immunol , vol.2 , pp. 336-345
    • Carding, S.R.1    Egan, P.J.2
  • 27
    • 0022475348 scopus 로고
    • Diversity of murine γ genes and expression in fetal and adult T lymphocytes
    • Heilig JS, Tonegawa S. Diversity of murine γ genes and expression in fetal and adult T lymphocytes. Nature 1986;322:836–40.
    • (1986) Nature , vol.322 , pp. 836-840
    • Heilig, J.S.1    Tonegawa, S.2
  • 29
  • 30
    • 62849124659 scopus 로고    scopus 로고
    • CD27 is a thymic determinant of the balance between interferon-γ- and interleukin 17-producing γδ T cell subsets
    • Ribot JC, deBarros A, Pang DJ, Neves JF, Peperzak V, Roberts SJ, et al. CD27 is a thymic determinant of the balance between interferon-γ- and interleukin 17-producing γδ T cell subsets. Nat Immunol 2009;10:427–36.
    • (2009) Nat Immunol , vol.10 , pp. 427-436
    • Ribot, J.C.1    deBarros, A.2    Pang, D.J.3    Neves, J.F.4    Peperzak, V.5    Roberts, S.J.6
  • 31
    • 84938926325 scopus 로고    scopus 로고
    • Adaptive immune-like γ/δ T lymphocytes share many common features with their α/β T cell counterparts
    • Lombes A, Durand A, Charvet C, Riviere M, Bonilla N, Auffray C, et al. Adaptive immune-like γ/δ T lymphocytes share many common features with their α/β T cell counterparts. J Immunol 2015;195:1449–58.
    • (2015) J Immunol , vol.195 , pp. 1449-1458
    • Lombes, A.1    Durand, A.2    Charvet, C.3    Riviere, M.4    Bonilla, N.5    Auffray, C.6
  • 32
    • 68649088121 scopus 로고    scopus 로고
    • Interleukin-1 and IL-23 induce innate IL-17 production from γδ T cells, amplifying Th17 responses and autoimmunity
    • Sutton CE, Lalor SJ, Sweeney CM, Brereton CF, Lavelle EC, Mills KH. Interleukin-1 and IL-23 induce innate IL-17 production from γδ T cells, amplifying Th17 responses and autoimmunity. Immunity 2009;31:331–41.
    • (2009) Immunity , vol.31 , pp. 331-341
    • Sutton, C.E.1    Lalor, S.J.2    Sweeney, C.M.3    Brereton, C.F.4    Lavelle, E.C.5    Mills, K.H.6
  • 33
    • 34547188748 scopus 로고    scopus 로고
    • IL-6 programs T(H)−17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways
    • Zhou L, Ivanov, II, Spolski R, Min R, Shenderov K, Egawa T, et al. IL-6 programs T(H)−17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways. Nat Immunol 2007;8:967–74.
    • (2007) Nat Immunol , vol.8 , pp. 967-974
    • Zhou, L.1    Ivanov, I.I.2    Spolski, R.3    Min, R.4    Shenderov, K.5    Egawa, T.6
  • 35
  • 36
    • 79960492398 scopus 로고    scopus 로고
    • IL-23 is critical for induction of arthritis, osteoclast formation, and maintenance of bone mass
    • Adamopoulos IE, Tessmer M, Chao CC, Adda S, Gorman D, Petro M, et al. IL-23 is critical for induction of arthritis, osteoclast formation, and maintenance of bone mass. J Immunol 2011;187:951–9.
    • (2011) J Immunol , vol.187 , pp. 951-959
    • Adamopoulos, I.E.1    Tessmer, M.2    Chao, C.C.3    Adda, S.4    Gorman, D.5    Petro, M.6
  • 38
    • 84885126123 scopus 로고    scopus 로고
    • The impact of tumor necrosis factor α inhibitors on radiographic progression in ankylosing spondylitis
    • Haroon N, Inman RD, Learch TJ, Weisman MH, Lee M, Rahbar MH, et al. The impact of tumor necrosis factor α inhibitors on radiographic progression in ankylosing spondylitis. Arthritis Rheum 2013;65:2645–54.
    • (2013) Arthritis Rheum , vol.65 , pp. 2645-2654
    • Haroon, N.1    Inman, R.D.2    Learch, T.J.3    Weisman, M.H.4    Lee, M.5    Rahbar, M.H.6
  • 39
    • 84906535154 scopus 로고    scopus 로고
    • The IL-23-IL-17 immune axis: from mechanisms to therapeutic testing
    • Gaffen SL, Jain R, Garg AV, Cua DJ. The IL-23-IL-17 immune axis: from mechanisms to therapeutic testing. Nat Rev Immunol 2014;14:585–600.
    • (2014) Nat Rev Immunol , vol.14 , pp. 585-600
    • Gaffen, S.L.1    Jain, R.2    Garg, A.V.3    Cua, D.J.4
  • 40
    • 38449093216 scopus 로고    scopus 로고
    • Exacerbation of collagen-induced arthritis by oligoclonal, IL-17-producing γδ T cells
    • Roark CL, French JD, Taylor MA, Bendele AM, Born WK, O'Brien RL. Exacerbation of collagen-induced arthritis by oligoclonal, IL-17-producing γδ T cells. J Immunol 2007;179:5576–83.
    • (2007) J Immunol , vol.179 , pp. 5576-5583
    • Roark, C.L.1    French, J.D.2    Taylor, M.A.3    Bendele, A.M.4    Born, W.K.5    O'Brien, R.L.6
  • 41
    • 68049097199 scopus 로고    scopus 로고
    • Gamma/delta T cells are the predominant source of interleukin-17 in affected joints in collagen-induced arthritis, but not in rheumatoid arthritis
    • Ito Y, Usui T, Kobayashi S, Iguchi-Hashimoto M, Ito H, Yoshitomi H, et al. Gamma/delta T cells are the predominant source of interleukin-17 in affected joints in collagen-induced arthritis, but not in rheumatoid arthritis. Arthritis Rheum 2009;60:2294–303.
    • (2009) Arthritis Rheum , vol.60 , pp. 2294-2303
    • Ito, Y.1    Usui, T.2    Kobayashi, S.3    Iguchi-Hashimoto, M.4    Ito, H.5    Yoshitomi, H.6
  • 42
    • 84933074064 scopus 로고    scopus 로고
    • IL-1 receptor antagonist-deficient mice develop autoimmune arthritis due to intrinsic activation of IL-17-producing CCR2(+)Vγ6(+)γδ T cells
    • Akitsu A, Ishigame H, Kakuta S, Chung SH, Ikeda S, Shimizu K, et al. IL-1 receptor antagonist-deficient mice develop autoimmune arthritis due to intrinsic activation of IL-17-producing CCR2(+)Vγ6(+)γδ T cells. Nat Commun 2015;6:7464.
    • (2015) Nat Commun , vol.6 , pp. 7464
    • Akitsu, A.1    Ishigame, H.2    Kakuta, S.3    Chung, S.H.4    Ikeda, S.5    Shimizu, K.6
  • 44
    • 0026705598 scopus 로고
    • Forre O. TCR γ/δ+ cell subsets in the synovial membranes of patients with rheumatoid arthritis and juvenile rheumatoid arthritis
    • Shen Y, Li S, Quayle AJ, Mellbye OJ, Natvig JB, Forre O. TCR γ/δ+ cell subsets in the synovial membranes of patients with rheumatoid arthritis and juvenile rheumatoid arthritis. Scand J Immunol 1992;36:533–40.
    • (1992) Scand J Immunol , vol.36 , pp. 533-540
    • Shen, Y.1    Li, S.2    Quayle, A.J.3    Mellbye, O.J.4    Natvig, J.B.5
  • 45
    • 79957824031 scopus 로고    scopus 로고
    • Gammadelta T cells in juvenile idiopathic arthritis: higher percentages of synovial Vδ1+ and Vγ9+ T cell subsets are associated with milder disease
    • Berkun Y, Bendersky A, Gerstein M, Goldstein I, Padeh S, Bank I. Gammadelta T cells in juvenile idiopathic arthritis: higher percentages of synovial Vδ1+ and Vγ9+ T cell subsets are associated with milder disease. J Rheumatol 2011;38:1123–9.
    • (2011) J Rheumatol , vol.38 , pp. 1123-1129
    • Berkun, Y.1    Bendersky, A.2    Gerstein, M.3    Goldstein, I.4    Padeh, S.5    Bank, I.6
  • 46
    • 84891747499 scopus 로고    scopus 로고
    • Proof of concept: enthesitis and new bone formation in spondyloarthritis are driven by mechanical strain and stromal cells
    • Jacques P, Lambrecht S, Verheugen E, Pauwels E, Kollias G, Armaka M, et al. Proof of concept: enthesitis and new bone formation in spondyloarthritis are driven by mechanical strain and stromal cells. Ann Rheum Dis 2014;73:437–45.
    • (2014) Ann Rheum Dis , vol.73 , pp. 437-445
    • Jacques, P.1    Lambrecht, S.2    Verheugen, E.3    Pauwels, E.4    Kollias, G.5    Armaka, M.6
  • 47
    • 84891748263 scopus 로고    scopus 로고
    • Spondyloarthritis: may the force be with you?
    • McGonagle D, Thomas RC, Schett G. Spondyloarthritis: may the force be with you? Ann Rheum Dis 2014;73:321–3.
    • (2014) Ann Rheum Dis , vol.73 , pp. 321-323
    • McGonagle, D.1    Thomas, R.C.2    Schett, G.3
  • 48
    • 80755180843 scopus 로고    scopus 로고
    • Pivotal role of dermal IL-17-producing γδ T cells in skin inflammation
    • Cai Y, Shen X, Ding C, Qi C, Li K, Li X, et al. Pivotal role of dermal IL-17-producing γδ T cells in skin inflammation. Immunity 2011;35:596–610.
    • (2011) Immunity , vol.35 , pp. 596-610
    • Cai, Y.1    Shen, X.2    Ding, C.3    Qi, C.4    Li, K.5    Li, X.6
  • 49
    • 84908374585 scopus 로고    scopus 로고
    • ZAP-70 genotype disrupts the relationship between microbiota and host, leading to spondyloarthritis and ileitis in SKG mice
    • Rehaume LM, Mondot S, Aguirre de Carcer D, Velasco J, Benham H, Hasnain SZ, et al. ZAP-70 genotype disrupts the relationship between microbiota and host, leading to spondyloarthritis and ileitis in SKG mice. Arthritis Rheumatol 2014;66:2780–92.
    • (2014) Arthritis Rheumatol , vol.66 , pp. 2780-2792
    • Rehaume, L.M.1    Mondot, S.2    Aguirre de Carcer, D.3    Velasco, J.4    Benham, H.5    Hasnain, S.Z.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.