메뉴 건너뛰기




Volumn 44, Issue 5, 2014, Pages 1320-1329

CCR7-mediated migration in the thymus controls γδ T-cell development

Author keywords

C C chemokine receptor CCR7; C C chemokine receptor CCR9; Intrathymic migration; T cells

Indexed keywords

CHEMOKINE RECEPTOR CCR7; CHEMOKINE RECEPTOR CCR9;

EID: 84899499135     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201344330     Document Type: Article
Times cited : (23)

References (69)
  • 1
    • 0024341218 scopus 로고
    • Positive and negative selection of T cell receptor V beta domains controlled by distinct cell populations in the thymus
    • Speiser, D. E., Lees, R. K., Hengartner, H., Zinkernagel, R. M. and MacDonald, H. R., Positive and negative selection of T cell receptor V beta domains controlled by distinct cell populations in the thymus. J. Exp. Med. 1989. 170: 2165-2170.
    • (1989) J. Exp. Med. , vol.170 , pp. 2165-2170
    • Speiser, D.E.1    Lees, R.K.2    Hengartner, H.3    Zinkernagel, R.M.4    MacDonald, H.R.5
  • 2
    • 0041884736 scopus 로고    scopus 로고
    • Thymic medullary epithelial cell differentiation, thymocyte emigration, and the control of autoimmunity require lympho-epithelial cross talk via LTbetaR
    • Boehm, T., Scheu, S., Pfeffer, K. and Bleul, C. C., Thymic medullary epithelial cell differentiation, thymocyte emigration, and the control of autoimmunity require lympho-epithelial cross talk via LTbetaR. J. Exp. Med. 2003. 198: 757-769.
    • (2003) J. Exp. Med. , vol.198 , pp. 757-769
    • Boehm, T.1    Scheu, S.2    Pfeffer, K.3    Bleul, C.C.4
  • 4
    • 0026604242 scopus 로고
    • Thymocytopoiesis is maintained by blood-borne precursors throughout postnatal life. A study in parabiotic mice
    • Donskoy, E. and Goldschneider, I., Thymocytopoiesis is maintained by blood-borne precursors throughout postnatal life. A study in parabiotic mice. J. Immunol. 1992. 148: 1604-1612.
    • (1992) J. Immunol. , vol.148 , pp. 1604-1612
    • Donskoy, E.1    Goldschneider, I.2
  • 5
    • 0035898387 scopus 로고    scopus 로고
    • Mapping precursor movement through the postnatal thymus reveals specific microenvironments supporting defined stages of early lymphoid development
    • Lind, E. F., Prockop, S. E., Porritt, H. E. and Petrie, H. T., Mapping precursor movement through the postnatal thymus reveals specific microenvironments supporting defined stages of early lymphoid development. J. Exp. Med. 2001. 194: 127-134.
    • (2001) J. Exp. Med. , vol.194 , pp. 127-134
    • Lind, E.F.1    Prockop, S.E.2    Porritt, H.E.3    Petrie, H.T.4
  • 6
    • 0141449952 scopus 로고    scopus 로고
    • Kinetics of steady-state differentiation and mapping of intrathymic-signaling environments by stem cell transplantation in nonirradiated mice
    • Porritt, H. E., Gordon, K. and Petrie, H. T., Kinetics of steady-state differentiation and mapping of intrathymic-signaling environments by stem cell transplantation in nonirradiated mice. J. Exp. Med. 2003. 198: 957-962.
    • (2003) J. Exp. Med. , vol.198 , pp. 957-962
    • Porritt, H.E.1    Gordon, K.2    Petrie, H.T.3
  • 8
    • 0025790455 scopus 로고
    • Developmental potential of the earliest precursor cells from the adult mouse thymus
    • Wu, L., Antica, M., Johnson, G. R., Scollay, R. and Shortman, K., Developmental potential of the earliest precursor cells from the adult mouse thymus. J. Exp. Med. 1991. 174: 1617-1627.
    • (1991) J. Exp. Med. , vol.174 , pp. 1617-1627
    • Wu, L.1    Antica, M.2    Johnson, G.R.3    Scollay, R.4    Shortman, K.5
  • 9
    • 0027153201 scopus 로고
    • A developmental pathway involving four phenotypically and functionally distinct subsets of CD3-CD4-CD8- triple-negative adult mouse thymocytes defined by CD44 and CD25 expression
    • Godfrey, D. I., Kennedy, J., Suda, T. and Zlotnik, A., A developmental pathway involving four phenotypically and functionally distinct subsets of CD3-CD4-CD8- triple-negative adult mouse thymocytes defined by CD44 and CD25 expression. J. Immunol. 1993. 150: 4244-4252.
    • (1993) J. Immunol. , vol.150 , pp. 4244-4252
    • Godfrey, D.I.1    Kennedy, J.2    Suda, T.3    Zlotnik, A.4
  • 10
    • 34247882592 scopus 로고    scopus 로고
    • Zoned out: functional mapping of stromal signaling microenvironments in the thymus
    • Petrie, H. T. and Zuniga-Pflucker, J. C., Zoned out: functional mapping of stromal signaling microenvironments in the thymus. Annu. Rev. Immunol. 2007. 25: 649-679.
    • (2007) Annu. Rev. Immunol. , vol.25 , pp. 649-679
    • Petrie, H.T.1    Zuniga-Pflucker, J.C.2
  • 11
    • 0028426281 scopus 로고
    • T cell receptor beta chain gene rearrangement and selection during thymocyte development in adult mice
    • Dudley, E. C., Petrie, H. T., Shah, L. M., Owen, M. J. and Hayday, A. C., T cell receptor beta chain gene rearrangement and selection during thymocyte development in adult mice. Immunity 1994. 1: 83-93.
    • (1994) Immunity , vol.1 , pp. 83-93
    • Dudley, E.C.1    Petrie, H.T.2    Shah, L.M.3    Owen, M.J.4    Hayday, A.C.5
  • 13
    • 33747605056 scopus 로고    scopus 로고
    • Visualization of the earliest steps of gammadelta T cell development in the adult thymus
    • Prinz, I., Sansoni, A., Kissenpfennig, A., Ardouin, L., Malissen, M. and Malissen, B., Visualization of the earliest steps of gammadelta T cell development in the adult thymus. Nat. Immunol. 2006. 7: 995-1003.
    • (2006) Nat. Immunol. , vol.7 , pp. 995-1003
    • Prinz, I.1    Sansoni, A.2    Kissenpfennig, A.3    Ardouin, L.4    Malissen, M.5    Malissen, B.6
  • 14
    • 53149130236 scopus 로고    scopus 로고
    • Thymic emigration: when and how T cells leave home
    • Weinreich, M. A. and Hogquist, K. A., Thymic emigration: when and how T cells leave home. J. Immunol. 2008. 181: 2265-2270.
    • (2008) J. Immunol. , vol.181 , pp. 2265-2270
    • Weinreich, M.A.1    Hogquist, K.A.2
  • 15
    • 1642580757 scopus 로고    scopus 로고
    • Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1
    • Matloubian, M., Lo, C. G., Cinamon, G., Lesneski, M. J., Xu, Y., Brinkmann, V., Allende, M. L. et al., Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1. Nature 2004. 427: 355-360.
    • (2004) Nature , vol.427 , pp. 355-360
    • Matloubian, M.1    Lo, C.G.2    Cinamon, G.3    Lesneski, M.J.4    Xu, Y.5    Brinkmann, V.6    Allende, M.L.7
  • 16
    • 34247379074 scopus 로고    scopus 로고
    • Promotion of lymphocyte egress into blood and lymph by distinct sources of sphingosine-1-phosphate
    • Pappu, R., Schwab, S. R., Cornelissen, I., Pereira, J. P., Regard, J. B., Xu, Y., Camerer, E. et al., Promotion of lymphocyte egress into blood and lymph by distinct sources of sphingosine-1-phosphate. Science 2007. 316: 295-298.
    • (2007) Science , vol.316 , pp. 295-298
    • Pappu, R.1    Schwab, S.R.2    Cornelissen, I.3    Pereira, J.P.4    Regard, J.B.5    Xu, Y.6    Camerer, E.7
  • 17
    • 33645289121 scopus 로고    scopus 로고
    • CD69 acts downstream of interferon-alpha/beta to inhibit S1P1 and lymphocyte egress from lymphoid organs
    • Shiow, L. R., Rosen, D. B., Brdickova, N., Xu, Y., An, J., Lanier, L. L., Cyster, J. G. et al., CD69 acts downstream of interferon-alpha/beta to inhibit S1P1 and lymphocyte egress from lymphoid organs. Nature 2006. 440: 540-544.
    • (2006) Nature , vol.440 , pp. 540-544
    • Shiow, L.R.1    Rosen, D.B.2    Brdickova, N.3    Xu, Y.4    An, J.5    Lanier, L.L.6    Cyster, J.G.7
  • 18
    • 36248956701 scopus 로고    scopus 로고
    • Finding a way out: lymphocyte egress from lymphoid organs
    • Schwab, S. R. and Cyster, J. G., Finding a way out: lymphocyte egress from lymphoid organs. Nat. Immunol. 2007. 8: 1295-1301.
    • (2007) Nat. Immunol. , vol.8 , pp. 1295-1301
    • Schwab, S.R.1    Cyster, J.G.2
  • 19
    • 18344385280 scopus 로고    scopus 로고
    • Role for CCR7 ligands in the emigration of newly generated T lymphocytes from the neonatal thymus
    • Ueno, T., Hara, K., Willis, M. S., Malin, M. A., Hopken, U. E., Gray, D. H., Matsushima, K. et al., Role for CCR7 ligands in the emigration of newly generated T lymphocytes from the neonatal thymus. Immunity 2002. 16: 205-218.
    • (2002) Immunity , vol.16 , pp. 205-218
    • Ueno, T.1    Hara, K.2    Willis, M.S.3    Malin, M.A.4    Hopken, U.E.5    Gray, D.H.6    Matsushima, K.7
  • 20
    • 0344850186 scopus 로고    scopus 로고
    • Cutting edge: developmental switches in chemokine responses during T cell maturation
    • Campbell, J. J., Pan, J. and Butcher, E. C., Cutting edge: developmental switches in chemokine responses during T cell maturation. J. Immunol. 1999. 163: 2353-2357.
    • (1999) J. Immunol. , vol.163 , pp. 2353-2357
    • Campbell, J.J.1    Pan, J.2    Butcher, E.C.3
  • 21
    • 0033986966 scopus 로고    scopus 로고
    • The chemokine TECK is expressed by thymic and intestinal epithelial cells and attracts double- and single-positive thymocytes expressing the TECK receptor CCR9
    • Wurbel, M. A., Philippe, J. M., Nguyen, C., Victorero, G., Freeman, T., Wooding, P., Miazek, A. et al., The chemokine TECK is expressed by thymic and intestinal epithelial cells and attracts double- and single-positive thymocytes expressing the TECK receptor CCR9. Eur. J. Immunol. 2000. 30: 262-271.
    • (2000) Eur. J. Immunol. , vol.30 , pp. 262-271
    • Wurbel, M.A.1    Philippe, J.M.2    Nguyen, C.3    Victorero, G.4    Freeman, T.5    Wooding, P.6    Miazek, A.7
  • 22
    • 0036136878 scopus 로고    scopus 로고
    • Characterization of CCR9 expression and CCL25/thymus-expressed chemokine responsiveness during T cell development: CD3(high)CD69+ thymocytes and gammadeltaTCR +thymocytes preferentially respond to CCL25
    • Uehara, S., Song, K., Farber, J. M. and Love, P. E., Characterization of CCR9 expression and CCL25/thymus-expressed chemokine responsiveness during T cell development: CD3(high)CD69+ thymocytes and gammadeltaTCR +thymocytes preferentially respond to CCL25. J. Immunol. 2002. 168: 134-142.
    • (2002) J. Immunol. , vol.168 , pp. 134-142
    • Uehara, S.1    Song, K.2    Farber, J.M.3    Love, P.E.4
  • 23
    • 0035525789 scopus 로고    scopus 로고
    • Mice lacking the CCR9 CC-chemokine receptor show a mild impairment of early T- and B-cell development and a reduction in T-cell receptor gammadelta(+) gut intraepithelial lymphocytes
    • Wurbel, M. A., Malissen, M., Guy-Grand, D., Meffre, E., Nussenzweig, M. C., Richelme, M., Carrier, A. et al., Mice lacking the CCR9 CC-chemokine receptor show a mild impairment of early T- and B-cell development and a reduction in T-cell receptor gammadelta(+) gut intraepithelial lymphocytes. Blood 2001. 98: 2626-2632.
    • (2001) Blood , vol.98 , pp. 2626-2632
    • Wurbel, M.A.1    Malissen, M.2    Guy-Grand, D.3    Meffre, E.4    Nussenzweig, M.C.5    Richelme, M.6    Carrier, A.7
  • 24
    • 1642289268 scopus 로고    scopus 로고
    • CCR7 directs the migration of thymocytes into the thymic medulla
    • Kwan, J. and Killeen, N., CCR7 directs the migration of thymocytes into the thymic medulla. J. Immunol. 2004. 172: 3999-4007.
    • (2004) J. Immunol. , vol.172 , pp. 3999-4007
    • Kwan, J.1    Killeen, N.2
  • 26
    • 19944427782 scopus 로고    scopus 로고
    • The role of CCL21 in recruitment of T-precursor cells to fetal thymi
    • Liu, C., Ueno, T., Kuse, S., Saito, F., Nitta, T., Piali, L., Nakano, H. et al., The role of CCL21 in recruitment of T-precursor cells to fetal thymi. Blood 2005. 105: 31-39.
    • (2005) Blood , vol.105 , pp. 31-39
    • Liu, C.1    Ueno, T.2    Kuse, S.3    Saito, F.4    Nitta, T.5    Piali, L.6    Nakano, H.7
  • 27
    • 77950418217 scopus 로고    scopus 로고
    • CC chemokine receptor 7 and 9 double-deficient hematopoietic progenitors are severely impaired in seeding the adult thymus
    • Krueger, A., Willenzon, S., Lyszkiewicz, M., Kremmer, E. and Forster, R., CC chemokine receptor 7 and 9 double-deficient hematopoietic progenitors are severely impaired in seeding the adult thymus. Blood 2010. 115: 1906-1912.
    • (2010) Blood , vol.115 , pp. 1906-1912
    • Krueger, A.1    Willenzon, S.2    Lyszkiewicz, M.3    Kremmer, E.4    Forster, R.5
  • 28
    • 39649113380 scopus 로고    scopus 로고
    • Impaired responsiveness to T-cell receptor stimulation and defective negative selection of thymocytes in CCR7-deficient mice
    • Davalos-Misslitz, A. C., Worbs, T., Willenzon, S., Bernhardt, G. and Forster, R., Impaired responsiveness to T-cell receptor stimulation and defective negative selection of thymocytes in CCR7-deficient mice. Blood 2007. 110: 4351-4359.
    • (2007) Blood , vol.110 , pp. 4351-4359
    • Davalos-Misslitz, A.C.1    Worbs, T.2    Willenzon, S.3    Bernhardt, G.4    Forster, R.5
  • 29
    • 70350131707 scopus 로고    scopus 로고
    • CCR7-mediated migration of developing thymocytes to the medulla is essential for negative selection to tissue-restricted antigens
    • Nitta, T., Nitta, S., Lei, Y., Lipp, M. and Takahama, Y., CCR7-mediated migration of developing thymocytes to the medulla is essential for negative selection to tissue-restricted antigens. Proc. Natl. Acad. Sci. USA 2009. 106: 17129-17133.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 17129-17133
    • Nitta, T.1    Nitta, S.2    Lei, Y.3    Lipp, M.4    Takahama, Y.5
  • 30
    • 4344668118 scopus 로고    scopus 로고
    • CCR7 signals are essential for cortex-medulla migration of developing thymocytes
    • Ueno, T., Saito, F., Gray, D. H., Kuse, S., Hieshima, K., Nakano, H., Kakiuchi, T. et al., CCR7 signals are essential for cortex-medulla migration of developing thymocytes. J. Exp. Med. 2004. 200: 493-505.
    • (2004) J. Exp. Med. , vol.200 , pp. 493-505
    • Ueno, T.1    Saito, F.2    Gray, D.H.3    Kuse, S.4    Hieshima, K.5    Nakano, H.6    Kakiuchi, T.7
  • 31
    • 32244432265 scopus 로고    scopus 로고
    • CCR7-dependent cortex-to-medulla migration of positively selected thymocytes is essential for establishing central tolerance
    • Kurobe, H., Liu, C., Ueno, T., Saito, F., Ohigashi, I., Seach, N., Arakaki, R. et al., CCR7-dependent cortex-to-medulla migration of positively selected thymocytes is essential for establishing central tolerance. Immunity 2006. 24: 165-177.
    • (2006) Immunity , vol.24 , pp. 165-177
    • Kurobe, H.1    Liu, C.2    Ueno, T.3    Saito, F.4    Ohigashi, I.5    Seach, N.6    Arakaki, R.7
  • 33
    • 34247369252 scopus 로고    scopus 로고
    • Regulatory T cells interfere with the development of bronchus-associated lymphoid tissue
    • Kocks, J. R., Davalos-Misslitz, A. C., Hintzen, G., Ohl, L. and Forster, R., Regulatory T cells interfere with the development of bronchus-associated lymphoid tissue. J. Exp. Med. 2007. 204: 723-734.
    • (2007) J. Exp. Med. , vol.204 , pp. 723-734
    • Kocks, J.R.1    Davalos-Misslitz, A.C.2    Hintzen, G.3    Ohl, L.4    Forster, R.5
  • 35
    • 77949879961 scopus 로고    scopus 로고
    • Cutting edge: spontaneous development of IL-17-producing gamma delta T cells in the thymus occurs via a TGF-beta 1-dependent mechanism
    • Do, J. S., Fink, P. J., Li, L., Spolski, R., Robinson, J., Leonard, W. J., Letterio, J. J. et al., Cutting edge: spontaneous development of IL-17-producing gamma delta T cells in the thymus occurs via a TGF-beta 1-dependent mechanism. J. Immunol. 2010. 184: 1675-1679.
    • (2010) J. Immunol. , vol.184 , pp. 1675-1679
    • Do, J.S.1    Fink, P.J.2    Li, L.3    Spolski, R.4    Robinson, J.5    Leonard, W.J.6    Letterio, J.J.7
  • 37
    • 81355147914 scopus 로고    scopus 로고
    • T cell receptor signalling in gammadelta cell development: strength isn't everything
    • Turchinovich, G. and Pennington, D. J., T cell receptor signalling in gammadelta cell development: strength isn't everything. Trends Immunol. 2011. 32: 567-573.
    • (2011) Trends Immunol. , vol.32 , pp. 567-573
    • Turchinovich, G.1    Pennington, D.J.2
  • 38
    • 84859890898 scopus 로고    scopus 로고
    • Intrathymic programming of effector fates in three molecularly distinct gammadelta T cell subtypes
    • Narayan, K., Sylvia, K. E., Malhotra, N., Yin, C. C., Martens, G., Vallerskog, T., Kornfeld, H. et al., Intrathymic programming of effector fates in three molecularly distinct gammadelta T cell subtypes. Nat. Immunol. 2012. 13: 511-518.
    • (2012) Nat. Immunol. , vol.13 , pp. 511-518
    • Narayan, K.1    Sylvia, K.E.2    Malhotra, N.3    Yin, C.C.4    Martens, G.5    Vallerskog, T.6    Kornfeld, H.7
  • 39
    • 0033214348 scopus 로고    scopus 로고
    • CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs
    • Forster, R., Schubel, A., Breitfeld, D., Kremmer, E., Renner-Muller, I., Wolf, E. and Lipp, M., CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs. Cell 1999. 99: 23-33.
    • (1999) Cell , vol.99 , pp. 23-33
    • Forster, R.1    Schubel, A.2    Breitfeld, D.3    Kremmer, E.4    Renner-Muller, I.5    Wolf, E.6    Lipp, M.7
  • 40
    • 80052025244 scopus 로고    scopus 로고
    • Afferent lymph-derived T cells and DCs use different chemokine receptor CCR7-dependent routes for entry into the lymph node and intranodal migration
    • Braun, A., Worbs, T., Moschovakis, G. L., Halle, S., Hoffmann, K., Bolter, J., Munk, A. et al., Afferent lymph-derived T cells and DCs use different chemokine receptor CCR7-dependent routes for entry into the lymph node and intranodal migration. Nat. Immunol. 2011. 12: 879-887.
    • (2011) Nat. Immunol. , vol.12 , pp. 879-887
    • Braun, A.1    Worbs, T.2    Moschovakis, G.L.3    Halle, S.4    Hoffmann, K.5    Bolter, J.6    Munk, A.7
  • 41
    • 0242579165 scopus 로고    scopus 로고
    • Flexible migration program regulates gamma delta T-cell involvement in humoral immunity
    • Brandes, M., Willimann, K., Lang, A. B., Nam, K. H., Jin, C., Brenner, M. B., Morita, C. T. et al., Flexible migration program regulates gamma delta T-cell involvement in humoral immunity. Blood 2003. 102: 3693-3701.
    • (2003) Blood , vol.102 , pp. 3693-3701
    • Brandes, M.1    Willimann, K.2    Lang, A.B.3    Nam, K.H.4    Jin, C.5    Brenner, M.B.6    Morita, C.T.7
  • 42
    • 84881022050 scopus 로고    scopus 로고
    • Ovine skin-recirculating gammadelta T cells express IFN-gamma and IL-17 and exit tissue independently of CCR7
    • Geherin, S. A., Lee, M. H., Wilson, R. P. and Debes, G. F., Ovine skin-recirculating gammadelta T cells express IFN-gamma and IL-17 and exit tissue independently of CCR7. Vet. Immunol. Immunopathol. 2013. 155: 87-97.
    • (2013) Vet. Immunol. Immunopathol. , vol.155 , pp. 87-97
    • Geherin, S.A.1    Lee, M.H.2    Wilson, R.P.3    Debes, G.F.4
  • 43
    • 84856004330 scopus 로고    scopus 로고
    • Gammadelta T cell homing to skin and migration to skin-draining lymph nodes is CCR7 independent
    • Vrieling, M., Santema, W., Van Rhijn, I., Rutten, V. and Koets, A., Gammadelta T cell homing to skin and migration to skin-draining lymph nodes is CCR7 independent. J. Immunol. 2012. 188: 578-584.
    • (2012) J. Immunol. , vol.188 , pp. 578-584
    • Vrieling, M.1    Santema, W.2    Van Rhijn, I.3    Rutten, V.4    Koets, A.5
  • 44
    • 0030587133 scopus 로고    scopus 로고
    • Inhibition of gamma delta T cell development and early thymocyte maturation in IL-7 -/- mice
    • Moore, T. A., von Freeden-Jeffry, U., Murray, R. and Zlotnik, A., Inhibition of gamma delta T cell development and early thymocyte maturation in IL-7 -/- mice. J. Immunol. 1996. 157: 2366-2373.
    • (1996) J. Immunol. , vol.157 , pp. 2366-2373
    • Moore, T.A.1    von Freeden-Jeffry, U.2    Murray, R.3    Zlotnik, A.4
  • 45
    • 0032441260 scopus 로고    scopus 로고
    • Interleukin 7 receptor control of T cell receptor gamma gene rearrangement: role of receptor-associated chains and locus accessibility
    • Durum, S. K., Candeias, S., Nakajima, H., Leonard, W. J., Baird, A. M., Berg, L. J. and Muegge, K., Interleukin 7 receptor control of T cell receptor gamma gene rearrangement: role of receptor-associated chains and locus accessibility. J. Exp. Med. 1998. 188: 2233-2241.
    • (1998) J. Exp. Med. , vol.188 , pp. 2233-2241
    • Durum, S.K.1    Candeias, S.2    Nakajima, H.3    Leonard, W.J.4    Baird, A.M.5    Berg, L.J.6    Muegge, K.7
  • 46
    • 0027199434 scopus 로고
    • Interleukin-7: a cofactor for V(D)J rearrangement of the T cell receptor beta gene
    • Muegge, K., Vila, M. P. and Durum, S. K., Interleukin-7: a cofactor for V(D)J rearrangement of the T cell receptor beta gene. Science 1993. 261: 93-95.
    • (1993) Science , vol.261 , pp. 93-95
    • Muegge, K.1    Vila, M.P.2    Durum, S.K.3
  • 50
    • 84857126644 scopus 로고    scopus 로고
    • Seeing is believing: illuminating the source of in vivo interleukin-7
    • Kim, G. Y., Hong, C. and Park, J. H., Seeing is believing: illuminating the source of in vivo interleukin-7. Immune. Netw. 2011. 11: 1-10.
    • (2011) Immune. Netw. , vol.11 , pp. 1-10
    • Kim, G.Y.1    Hong, C.2    Park, J.H.3
  • 51
    • 84862821294 scopus 로고    scopus 로고
    • Intrathymic IL-7: the where, when, and why of IL-7 signaling during T cell development
    • Hong, C., Luckey, M. A. and Park, J. H., Intrathymic IL-7: the where, when, and why of IL-7 signaling during T cell development. Semin. Immunol. 2012. 24: 151-158.
    • (2012) Semin. Immunol. , vol.24 , pp. 151-158
    • Hong, C.1    Luckey, M.A.2    Park, J.H.3
  • 52
    • 51349111243 scopus 로고    scopus 로고
    • The tumor necrosis factor family receptors RANK and CD40 cooperatively establish the thymic medullary microenvironment and self-tolerance
    • Akiyama, T., Shimo, Y., Yanai, H., Qin, J., Ohshima, D., Maruyama, Y., Asaumi, Y. et al., The tumor necrosis factor family receptors RANK and CD40 cooperatively establish the thymic medullary microenvironment and self-tolerance. Immunity 2008. 29: 423-437.
    • (2008) Immunity , vol.29 , pp. 423-437
    • Akiyama, T.1    Shimo, Y.2    Yanai, H.3    Qin, J.4    Ohshima, D.5    Maruyama, Y.6    Asaumi, Y.7
  • 53
    • 51349092893 scopus 로고    scopus 로고
    • The cytokine RANKL produced by positively selected thymocytes fosters medullary thymic epithelial cells that express autoimmune regulator
    • Hikosaka, Y., Nitta, T., Ohigashi, I., Yano, K., Ishimaru, N., Hayashi, Y., Matsumoto, M. et al., The cytokine RANKL produced by positively selected thymocytes fosters medullary thymic epithelial cells that express autoimmune regulator. Immunity 2008. 29: 438-450.
    • (2008) Immunity , vol.29 , pp. 438-450
    • Hikosaka, Y.1    Nitta, T.2    Ohigashi, I.3    Yano, K.4    Ishimaru, N.5    Hayashi, Y.6    Matsumoto, M.7
  • 54
    • 42649092113 scopus 로고    scopus 로고
    • Skint1, the prototype of a newly identified immunoglobulin superfamily gene cluster, positively selects epidermal gammadelta T cells
    • Boyden, L. M., Lewis, J. M., Barbee, S. D., Bas, A., Girardi, M., Hayday, A. C., Tigelaar, R. E. et al., Skint1, the prototype of a newly identified immunoglobulin superfamily gene cluster, positively selects epidermal gammadelta T cells. Nat. Genet. 2008. 40: 656-662.
    • (2008) Nat. Genet. , vol.40 , pp. 656-662
    • Boyden, L.M.1    Lewis, J.M.2    Barbee, S.D.3    Bas, A.4    Girardi, M.5    Hayday, A.C.6    Tigelaar, R.E.7
  • 55
    • 84858795036 scopus 로고    scopus 로고
    • Rank signaling links the development of invariant gammadelta T cell progenitors and Aire(+) medullary epithelium
    • Roberts, N. A., White, A. J., Jenkinson, W. E., Turchinovich, G., Nakamura, K., Withers, D. R., McConnell, F. M. et al., Rank signaling links the development of invariant gammadelta T cell progenitors and Aire(+) medullary epithelium. Immunity 2012. 36: 427-437.
    • (2012) Immunity , vol.36 , pp. 427-437
    • Roberts, N.A.1    White, A.J.2    Jenkinson, W.E.3    Turchinovich, G.4    Nakamura, K.5    Withers, D.R.6    McConnell, F.M.7
  • 56
    • 79960447248 scopus 로고    scopus 로고
    • Skint-1 identifies a common molecular mechanism for the development of interferon-gamma-secreting versus interleukin-17-secreting gammadelta T cells
    • Turchinovich, G. and Hayday, A. C., Skint-1 identifies a common molecular mechanism for the development of interferon-gamma-secreting versus interleukin-17-secreting gammadelta T cells. Immunity 2011. 35: 59-68.
    • (2011) Immunity , vol.35 , pp. 59-68
    • Turchinovich, G.1    Hayday, A.C.2
  • 57
    • 13644251707 scopus 로고    scopus 로고
    • Lymphotoxin-mediated regulation of gammadelta cell differentiation by alphabeta T cell progenitors
    • Silva-Santos, B., Pennington, D. J. and Hayday, A. C., Lymphotoxin-mediated regulation of gammadelta cell differentiation by alphabeta T cell progenitors. Science 2005. 307: 925-928.
    • (2005) Science , vol.307 , pp. 925-928
    • Silva-Santos, B.1    Pennington, D.J.2    Hayday, A.C.3
  • 58
    • 84877821233 scopus 로고    scopus 로고
    • Lymphotoxin beta receptor regulates the development of CCL21-expressing subset of postnatal medullary thymic epithelial cells
    • Lkhagvasuren, E., Sakata, M., Ohigashi, I. and Takahama, Y., Lymphotoxin beta receptor regulates the development of CCL21-expressing subset of postnatal medullary thymic epithelial cells. J. Immunol. 2013. 190: 5110-5117.
    • (2013) J. Immunol. , vol.190 , pp. 5110-5117
    • Lkhagvasuren, E.1    Sakata, M.2    Ohigashi, I.3    Takahama, Y.4
  • 59
    • 13844313930 scopus 로고    scopus 로고
    • IMMUNOLOGY: enhanced: thymic regulation-hidden in plain sight
    • Rothenberg, E. V., IMMUNOLOGY: enhanced: thymic regulation-hidden in plain sight. Science 2005. 307: 858-859.
    • (2005) Science , vol.307 , pp. 858-859
    • Rothenberg, E.V.1
  • 60
    • 62849124659 scopus 로고    scopus 로고
    • CD27 is a thymic determinant of the balance between interferon-gamma- and interleukin 17-producing gammadelta T cell subsets
    • Ribot, J. C., deBarros, A., Pang, D. J., Neves, J. F., Peperzak, V., Roberts, S. J., Girardi, M. et al., CD27 is a thymic determinant of the balance between interferon-gamma- and interleukin 17-producing gammadelta T cell subsets. Nat. Immunol. 2009. 10: 427-436.
    • (2009) Nat. Immunol. , vol.10 , pp. 427-436
    • Ribot, J.C.1    deBarros, A.2    Pang, D.J.3    Neves, J.F.4    Peperzak, V.5    Roberts, S.J.6    Girardi, M.7
  • 61
    • 78149482139 scopus 로고    scopus 로고
    • Intra- and intercompartmental movement of gammadelta T cells: intestinal intraepithelial and peripheral gammadelta T cells represent exclusive nonoverlapping populations with distinct migration characteristics
    • Chennupati, V., Worbs, T., Liu, X., Malinarich, F. H., Schmitz, S., Haas, J. D., Malissen, B. et al., Intra- and intercompartmental movement of gammadelta T cells: intestinal intraepithelial and peripheral gammadelta T cells represent exclusive nonoverlapping populations with distinct migration characteristics. J. Immunol. 2010. 185: 5160-5168.
    • (2010) J. Immunol. , vol.185 , pp. 5160-5168
    • Chennupati, V.1    Worbs, T.2    Liu, X.3    Malinarich, F.H.4    Schmitz, S.5    Haas, J.D.6    Malissen, B.7
  • 62
    • 67649196945 scopus 로고    scopus 로고
    • Cutting edge: gammadelta intraepithelial lymphocytes of the small intestine are not biased toward thymic antigens
    • Jensen, K. D., Shin, S. and Chien, Y. H., Cutting edge: gammadelta intraepithelial lymphocytes of the small intestine are not biased toward thymic antigens. J. Immunol. 2009. 182: 7348-7351.
    • (2009) J. Immunol. , vol.182 , pp. 7348-7351
    • Jensen, K.D.1    Shin, S.2    Chien, Y.H.3
  • 63
  • 64
    • 49049115394 scopus 로고    scopus 로고
    • IL-17A inhibits the expansion of IL-17A-producing T cells in mice through "short-loop" inhibition via IL-17 receptor
    • Smith, E., Stark, M. A., Zarbock, A., Burcin, T. L., Bruce, A. C., Vaswani, D., Foley, P. et al., IL-17A inhibits the expansion of IL-17A-producing T cells in mice through "short-loop" inhibition via IL-17 receptor. J. Immunol. 2008. 181: 1357-1364.
    • (2008) J. Immunol. , vol.181 , pp. 1357-1364
    • Smith, E.1    Stark, M.A.2    Zarbock, A.3    Burcin, T.L.4    Bruce, A.C.5    Vaswani, D.6    Foley, P.7
  • 65
    • 84864325431 scopus 로고    scopus 로고
    • Development of interleukin-17-producing gammadelta T cells is restricted to a functional embryonic wave
    • Haas, J. D., Ravens, S., Duber, S., Sandrock, I., Oberdorfer, L., Kashani, E., Chennupati, V. et al., Development of interleukin-17-producing gammadelta T cells is restricted to a functional embryonic wave. Immunity 2012. 37: 48-59.
    • (2012) Immunity , vol.37 , pp. 48-59
    • Haas, J.D.1    Ravens, S.2    Duber, S.3    Sandrock, I.4    Oberdorfer, L.5    Kashani, E.6    Chennupati, V.7
  • 66
    • 15244344110 scopus 로고    scopus 로고
    • Phagocytosis of apoptotic neutrophils regulates granulopoiesis via IL-23 and IL-17
    • Stark, M. A., Huo, Y., Burcin, T. L., Morris, M. A., Olson, T. S. and Ley, K., Phagocytosis of apoptotic neutrophils regulates granulopoiesis via IL-23 and IL-17. Immunity 2005. 22: 285-294.
    • (2005) Immunity , vol.22 , pp. 285-294
    • Stark, M.A.1    Huo, Y.2    Burcin, T.L.3    Morris, M.A.4    Olson, T.S.5    Ley, K.6
  • 67
    • 0026485046 scopus 로고
    • Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages
    • Mombaerts, P., Clarke, A. R., Rudnicki, M. A., Iacomini, J., Itohara, S., Lafaille, J. J., Wang, L. et al., Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages. Nature 1992. 360: 225-231.
    • (1992) Nature , vol.360 , pp. 225-231
    • Mombaerts, P.1    Clarke, A.R.2    Rudnicki, M.A.3    Iacomini, J.4    Itohara, S.5    Lafaille, J.J.6    Wang, L.7
  • 68
    • 0024270586 scopus 로고
    • Monoclonal antibodies reactive with subsets of mouse and human thymic epithelial cells
    • Rouse, R. V., Bolin, L. M., Bender, J. R. and Kyewski, B. A., Monoclonal antibodies reactive with subsets of mouse and human thymic epithelial cells. J. Histochem. Cytochem. 1988. 36: 1511-1517.
    • (1988) J. Histochem. Cytochem. , vol.36 , pp. 1511-1517
    • Rouse, R.V.1    Bolin, L.M.2    Bender, J.R.3    Kyewski, B.A.4
  • 69
    • 3042627641 scopus 로고    scopus 로고
    • Induction of T cell development and establishment of T cell competence from embryonic stem cells differentiated in vitro
    • Schmitt, T. M., de Pooter, R. F., Gronski, M. A., Cho, S. K., Ohashi, P. S. and Zuniga-Pflucker, J. C., Induction of T cell development and establishment of T cell competence from embryonic stem cells differentiated in vitro. Nat. Immunol. 2004. 5: 410-417.
    • (2004) Nat. Immunol. , vol.5 , pp. 410-417
    • Schmitt, T.M.1    de Pooter, R.F.2    Gronski, M.A.3    Cho, S.K.4    Ohashi, P.S.5    Zuniga-Pflucker, J.C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.