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Volumn 28, Issue 5, 2014, Pages 765-777

Bone formation in axial spondyloarthritis

Author keywords

Ankylosing spondylitis; Anti TNF; Bone; Cartilage; Inflammation; Spondyloarthritis

Indexed keywords

ANOCTAMIN 6; AUTOANTIBODY; DISEASE MODIFYING ANTIRHEUMATIC DRUG; EGF LIKE REPEATS AND DISCOIDIN I LIKE DOMAINS 3; HLA B27 ANTIGEN; INTEGRIN RECEPTOR; INTERLEUKIN 17; INTERLEUKIN 23; MEMBRANE PROTEIN; NOGGIN; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN E RECEPTOR 4; SCLEROSTIN; TUMOR NECROSIS FACTOR INHIBITOR; UNCLASSIFIED DRUG;

EID: 84927933558     PISSN: 15216942     EISSN: 15321770     Source Type: Journal    
DOI: 10.1016/j.berh.2014.10.008     Document Type: Review
Times cited : (46)

References (105)
  • 1
    • 79959359494 scopus 로고    scopus 로고
    • Spondyloarthritis
    • Dougados M, Baeten D. Spondyloarthritis. Lancet 2011;377(9783):2127-37.
    • (2011) Lancet , vol.377 , Issue.9783 , pp. 2127-2137
    • Dougados, M.1    Baeten, D.2
  • 2
    • 67649831600 scopus 로고    scopus 로고
    • The assessment of spondyloarthritis international society (ASAS) handbook: A guide to assess spondyloarthritis
    • Sieper J, Rudwaleit M, Baraliakos X, et al. The assessment of spondyloarthritis international society (ASAS) handbook: a guide to assess spondyloarthritis. Ann Rheum Dis 2009;68(Suppl. 2). ii1-44.
    • (2009) Ann Rheum Dis , vol.68 , pp. ii1-44
    • Sieper, J.1    Rudwaleit, M.2    Baraliakos, X.3
  • 3
    • 78650679234 scopus 로고    scopus 로고
    • The assessment of spondyloarthritis international society classification criteria for peripheral spondyloarthritis and for spondyloarthritis in general
    • Rudwaleit M, van der Heijde D, Landewe R, et al. The assessment of spondyloarthritis international society classification criteria for peripheral spondyloarthritis and for spondyloarthritis in general. Ann Rheum Dis 2011;70(1):25-31.
    • (2011) Ann Rheum Dis , vol.70 , Issue.1 , pp. 25-31
    • Rudwaleit, M.1    Van Der Heijde, D.2    Landewe, R.3
  • 4
    • 67449128733 scopus 로고    scopus 로고
    • The development of assessment of SpondyloArthritis international society classification criteria for axial spondyloarthritis (part II): Validation and final selection
    • Rudwaleit M, van der Heijde D, Landewe R, et al. The development of assessment of SpondyloArthritis international society classification criteria for axial spondyloarthritis (part II): validation and final selection. Ann Rheum Dis 2009; 68(6):777-83.
    • (2009) Ann Rheum Dis , vol.68 , Issue.6 , pp. 777-783
    • Rudwaleit, M.1    Van Der Heijde, D.2    Landewe, R.3
  • 5
    • 77955454360 scopus 로고    scopus 로고
    • Both structural damage and inflammation of the spine contribute to impairment of spinal mobility in patients with ankylosing spondylitis
    • Machado P, Landewe R, Braun J, et al. Both structural damage and inflammation of the spine contribute to impairment of spinal mobility in patients with ankylosing spondylitis. Ann Rheum Dis 2010;69(8):1465-70.
    • (2010) Ann Rheum Dis , vol.69 , Issue.8 , pp. 1465-1470
    • Machado, P.1    Landewe, R.2    Braun, J.3
  • 6
    • 70450171014 scopus 로고    scopus 로고
    • Work disability in patients with ankylosing spondylitis
    • Ariza-Ariza R, Hernandez-Cruz B, Collantes E, et al. Work disability in patients with ankylosing spondylitis. J Rheumatol 2009;36(11):2512-6.
    • (2009) J Rheumatol , vol.36 , Issue.11 , pp. 2512-2516
    • Ariza-Ariza, R.1    Hernandez-Cruz, B.2    Collantes, E.3
  • 7
    • 80053569408 scopus 로고    scopus 로고
    • Increased mortality in ankylosing spondylitis is related to disease activity
    • Bakland G, Gran JT, Nossent JC. Increased mortality in ankylosing spondylitis is related to disease activity. Ann Rheum Dis 2011;70(11):1921-5.
    • (2011) Ann Rheum Dis , vol.70 , Issue.11 , pp. 1921-1925
    • Bakland, G.1    Gran, J.T.2    Nossent, J.C.3
  • 8
    • 79952259980 scopus 로고    scopus 로고
    • Impact of ankylosing spondylitis on work in patients across the UK
    • Healey EL, Haywood KL, Jordan KP, et al. Impact of ankylosing spondylitis on work in patients across the UK. Scand J Rheumatol 2011;40(1):34-40.
    • (2011) Scand J Rheumatol , vol.40 , Issue.1 , pp. 34-40
    • Healey, E.L.1    Haywood, K.L.2    Jordan, K.P.3
  • 9
    • 84922407440 scopus 로고    scopus 로고
    • Efficacy of TNFalpha blockers in patients with ankylosing spondylitis and nonradiographic axial spondyloarthritis: A meta-analysis
    • [in press]
    • Callhoff J, Sieper J, Weiss A, et al. Efficacy of TNFalpha blockers in patients with ankylosing spondylitis and nonradiographic axial spondyloarthritis: a meta-analysis. Ann Rheum Dis 2014 [in press].
    • (2014) Ann Rheum Dis
    • Callhoff, J.1    Sieper, J.2    Weiss, A.3
  • 10
    • 67449084394 scopus 로고    scopus 로고
    • The natural course of radiographic progression in ankylosing spondylitiseevidence for major individual variations in a large proportion of patients
    • Baraliakos X, Listing J, von der Recke A, et al. The natural course of radiographic progression in ankylosing spondylitiseevidence for major individual variations in a large proportion of patients. J Rheumatol 2009;36(5):997-1002.
    • (2009) J Rheumatol , vol.36 , Issue.5 , pp. 997-1002
    • Baraliakos, X.1    Listing, J.2    Von Der Recke, A.3
  • 11
    • 0015938046 scopus 로고
    • Ankylosing spondylitis and HL-A 27
    • Brewerton DA, Hart FD, Nicholls A, et al. Ankylosing spondylitis and HL-A 27. Lancet 1973;1(7809):904-7.
    • (1973) Lancet , vol.1 , Issue.7809 , pp. 904-907
    • Brewerton, D.A.1    Hart, F.D.2    Nicholls, A.3
  • 12
    • 79959775441 scopus 로고    scopus 로고
    • Rates and predictors of radiographic sacroiliitis progression over 2 years in patients with axial spondyloarthritis
    • Poddubnyy D, Rudwaleit M, Haibel H, et al. Rates and predictors of radiographic sacroiliitis progression over 2 years in patients with axial spondyloarthritis. Ann Rheum Dis 2011;70(8):1369-74.
    • (2011) Ann Rheum Dis , vol.70 , Issue.8 , pp. 1369-1374
    • Poddubnyy, D.1    Rudwaleit, M.2    Haibel, H.3
  • 13
    • 84860436138 scopus 로고    scopus 로고
    • Baseline radiographic damage elevated acute-phase reactant levels and cigarette smoking status predict spinal radiographic progression in early axial spondylarthritis
    • Poddubnyy D, Haibel H, Listing J, et al. Baseline radiographic damage, elevated acute-phase reactant levels, and cigarette smoking status predict spinal radiographic progression in early axial spondylarthritis. Arthritis Rheum 2012; 64(5):1388-98.
    • (2012) Arthritis Rheum , vol.64 , Issue.5 , pp. 1388-1398
    • Poddubnyy, D.1    Haibel, H.2    Listing, J.3
  • 14
    • 67650446225 scopus 로고    scopus 로고
    • Clinical and immunogenetic prognostic factors for radiographic severity in ankylosing spondylitis
    • Ward MM, Hendrey MR, Malley JD, et al. Clinical and immunogenetic prognostic factors for radiographic severity in ankylosing spondylitis. Arthritis Rheum 2009;61(7):859-66.
    • (2009) Arthritis Rheum , vol.61 , Issue.7 , pp. 859-866
    • Ward, M.M.1    Hendrey, M.R.2    Malley, J.D.3
  • 15
    • 84865179765 scopus 로고    scopus 로고
    • Genetic polymorphisms inside and outside the MHC improve prediction of AS radiographic severity in addition to clinical variables
    • Bartolome N, Szczypiorska M, Sanchez A, et al. Genetic polymorphisms inside and outside the MHC improve prediction of AS radiographic severity in addition to clinical variables. Rheumatol (Oxford) 2012;51(8):1471-8.
    • (2012) Rheumatol (Oxford) , vol.51 , Issue.8 , pp. 1471-1478
    • Bartolome, N.1    Szczypiorska, M.2    Sanchez, A.3
  • 16
    • 33646019842 scopus 로고    scopus 로고
    • The LDL receptor-related protein LRP6 mediates internalization and lethality of anthrax toxin
    • WeiW, Lu Q, Chaudry GJ, et al. The LDL receptor-related protein LRP6 mediates internalization and lethality of anthrax toxin. Cell 2006;124(6):1141-54.
    • (2006) Cell , vol.124 , Issue.6 , pp. 1141-1154
    • Weiw Lu, Q.1    Chaudry, G.J.2
  • 17
    • 84878546253 scopus 로고    scopus 로고
    • To Wnt or not to Wnt: The bone and joint health dilemma
    • Lories RJ, Corr M, Lane NE. To Wnt or not to Wnt: the bone and joint health dilemma. Nat Rev Rheumatol 2013;9(6): 328-39.
    • (2013) Nat Rev Rheumatol , vol.9 , Issue.6 , pp. 328-339
    • Lories, R.J.1    Corr, M.2    Lane, N.E.3
  • 18
    • 18044386744 scopus 로고    scopus 로고
    • LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development
    • Gong Y, Slee RB, Fukai N, et al. LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development. Cell 2001;107(4):513-23.
    • (2001) Cell , vol.107 , Issue.4 , pp. 513-523
    • Gong, Y.1    Slee, R.B.2    Fukai, N.3
  • 19
    • 65449165333 scopus 로고    scopus 로고
    • EP2 and EP4 receptors differentially mediate MAPK pathways underlying anabolic actions of prostaglandin E2 on bone formation in rat calvaria cell cultures
    • Minamizaki T, Yoshiko Y, Kozai K, et al. EP2 and EP4 receptors differentially mediate MAPK pathways underlying anabolic actions of prostaglandin E2 on bone formation in rat calvaria cell cultures. Bone 2009;44(6):1177-85.
    • (2009) Bone , vol.44 , Issue.6 , pp. 1177-1185
    • Minamizaki, T.1    Yoshiko, Y.2    Kozai, K.3
  • 20
    • 34848828230 scopus 로고    scopus 로고
    • Enhancing effects of a prostaglandin EP4 receptor agonist on recombinant human bone morphogenetic protein-2 mediated spine fusion in a rabbit model
    • Namikawa T, Terai H, Hoshino M, et al. Enhancing effects of a prostaglandin EP4 receptor agonist on recombinant human bone morphogenetic protein-2 mediated spine fusion in a rabbit model. Spine 2007;32(21):2294-9.
    • (2007) Spine , vol.32 , Issue.21 , pp. 2294-2299
    • Namikawa, T.1    Terai, H.2    Hoshino, M.3
  • 21
    • 24944446761 scopus 로고    scopus 로고
    • Augmentation of bone morphogenetic protein-induced bone mass by local delivery of a prostaglandin e EP4 receptor agonist
    • Toyoda H, Terai H, Sasaoka R, et al. Augmentation of bone morphogenetic protein-induced bone mass by local delivery of a prostaglandin E EP4 receptor agonist. Bone 2005;37(4):555-62.
    • (2005) Bone , vol.37 , Issue.4 , pp. 555-562
    • Toyoda, H.1    Terai, H.2    Sasaoka, R.3
  • 22
    • 84655176642 scopus 로고    scopus 로고
    • A genome-wide association study in Han Chinese identifies new susceptibility loci for ankylosing spondylitis
    • Lin Z, Bei JX, Shen M, et al. A genome-wide association study in Han Chinese identifies new susceptibility loci for ankylosing spondylitis. Nat Genet 2012;44(1):73-7.
    • (2012) Nat Genet , vol.44 , Issue.1 , pp. 73-77
    • Lin, Z.1    Bei, J.X.2    Shen, M.3
  • 23
    • 0141651924 scopus 로고    scopus 로고
    • Chondrodysplasia of gene knockout mice for aggrecan and link protein
    • Watanabe H, Yamada Y. Chondrodysplasia of gene knockout mice for aggrecan and link protein. Glycoconj J 2002; 19(4-5):269-73.
    • (2002) Glycoconj J , vol.19 , Issue.4-5 , pp. 269-273
    • Watanabe, H.1    Yamada, Y.2
  • 24
    • 0032931819 scopus 로고    scopus 로고
    • Mice lacking link protein develop dwarfism and craniofacial abnormalities
    • Watanabe H, Yamada Y. Mice lacking link protein develop dwarfism and craniofacial abnormalities. Nat Genet 1999; 21(2):225-9.
    • (1999) Nat Genet , vol.21 , Issue.2 , pp. 225-229
    • Watanabe, H.1    Yamada, Y.2
  • 25
    • 79956225910 scopus 로고    scopus 로고
    • Single-nucleotide polymorphism in the hyaluronan and proteoglycan link protein 1 (HAPLN1) gene is associated with spinal osteophyte formation and disc degeneration in Japanese women
    • Urano T, Narusawa K, Shiraki M, et al. Single-nucleotide polymorphism in the hyaluronan and proteoglycan link protein 1 (HAPLN1) gene is associated with spinal osteophyte formation and disc degeneration in Japanese women. Eur Spine J Off Publ Eur Spine Soc Eur Spinal Deform Soc Eur Sect Cerv Spine Res Soc 2011;20(4):572-7.
    • (2011) Eur Spine J off Publ Eur Spine Soc Eur Spinal Deform Soc Eur Sect Cerv Spine Res Soc , vol.20 , Issue.4 , pp. 572-577
    • Urano, T.1    Narusawa, K.2    Shiraki, M.3
  • 26
    • 56449122732 scopus 로고    scopus 로고
    • Del-1, an endogenous leukocyte-endothelial adhesion inhibitor, limits inflammatory cell recruitment
    • Choi EY, Chavakis E, Czabanka MA, et al. Del-1, an endogenous leukocyte-endothelial adhesion inhibitor, limits inflammatory cell recruitment. Science 2008;322(5904):1101-4.
    • (2008) Science , vol.322 , Issue.5904 , pp. 1101-1104
    • Choi, E.Y.1    Chavakis, E.2    Czabanka, M.A.3
  • 27
    • 84863393385 scopus 로고    scopus 로고
    • The leukocyte integrin antagonist del-1 inhibits IL-17-mediated inflammatory bone loss
    • Eskan MA, Jotwani R, Abe T, et al. The leukocyte integrin antagonist del-1 inhibits IL-17-mediated inflammatory bone loss. Nat Immunol 2012;13(5):465-73.
    • (2012) Nat Immunol , vol.13 , Issue.5 , pp. 465-473
    • Eskan, M.A.1    Jotwani, R.2    Abe, T.3
  • 28
    • 77956562584 scopus 로고    scopus 로고
    • Anterior neural development requires del1 a matrix-associated protein that attenuates canonical Wnt signaling via the Ror2 pathway
    • Takai A, Inomata H, Arakawa A, et al. Anterior neural development requires del1, a matrix-associated protein that attenuates canonical Wnt signaling via the Ror2 pathway. Development 2010;137(19):3293-302.
    • (2010) Development , vol.137 , Issue.19 , pp. 3293-3302
    • Takai, A.1    Inomata, H.2    Arakawa, A.3
  • 29
    • 84872471468 scopus 로고    scopus 로고
    • Inactivation of anoctamin-6/Tmem16f, a regulator of phosphatidylserine scrambling in osteoblasts, leads to decreased mineral deposition in skeletal tissues
    • Ehlen HW, Chinenkova M, Moser M, et al. Inactivation of anoctamin-6/Tmem16f, a regulator of phosphatidylserine scrambling in osteoblasts, leads to decreased mineral deposition in skeletal tissues. J Bone Min Res Off J Am Soc Bone Min Res 2013;28(2):246-59.
    • (2013) J Bone Min Res off J Am Soc Bone Min Res , vol.28 , Issue.2 , pp. 246-259
    • Ehlen, H.W.1    Chinenkova, M.2    Moser, M.3
  • 30
    • 84866178568 scopus 로고    scopus 로고
    • Radiographic severity of ankylosing spondylitis is associated with polymorphism of the large multifunctional peptidase 2 gene in the spondyloarthritis research consortium of Canada cohort
    • Haroon N, Maksymowych WP, Rahman P, et al. Radiographic severity of ankylosing spondylitis is associated with polymorphism of the large multifunctional peptidase 2 gene in the spondyloarthritis research consortium of Canada cohort. Arthritis Rheum 2012;64(4):1119-26.
    • (2012) Arthritis Rheum , vol.64 , Issue.4 , pp. 1119-1126
    • Haroon, N.1    Maksymowych, W.P.2    Rahman, P.3
  • 31
    • 0028930052 scopus 로고
    • Polymorphism in the LMP2 gene influences susceptibility to extraspinal disease in HLA-B27 positive individuals with ankylosing spondylitis
    • Maksymowych WP, Suarez-Almazor M, Chou CT, et al. Polymorphism in the LMP2 gene influences susceptibility to extraspinal disease in HLA-B27 positive individuals with ankylosing spondylitis. Ann Rheum Dis 1995;54(4):321-4.
    • (1995) Ann Rheum Dis , vol.54 , Issue.4 , pp. 321-324
    • Maksymowych, W.P.1    Suarez-Almazor, M.2    Chou, C.T.3
  • 32
    • 84857924158 scopus 로고    scopus 로고
    • Endoplasmic reticulum aminopeptidase 1 (ERAP1) exhibits functionally significant interaction with HLA-B27 and relates to subtype specificity in ankylosing spondylitis
    • Haroon N, Tsui FW, Uchanska-Ziegler B, et al. Endoplasmic reticulum aminopeptidase 1 (ERAP1) exhibits functionally significant interaction with HLA-B27 and relates to subtype specificity in ankylosing spondylitis. Ann Rheum Dis 2012; 71(4):589-95.
    • (2012) Ann Rheum Dis , vol.71 , Issue.4 , pp. 589-595
    • Haroon, N.1    Tsui, F.W.2    Uchanska-Ziegler, B.3
  • 33
    • 84934906038 scopus 로고    scopus 로고
    • Association study of genes related to bone formation and resorption and the extent of radiographic change in ankylosing spondylitis
    • [in press]
    • Cortes A, Maksymowych WP, Wordsworth BP, et al. Association study of genes related to bone formation and resorption and the extent of radiographic change in ankylosing spondylitis. Ann Rheum Dis 2014 [in press].
    • (2014) Ann Rheum Dis
    • Cortes, A.1    Maksymowych, W.P.2    Wordsworth, B.P.3
  • 34
    • 0021021940 scopus 로고
    • The enthesopathy of ankylosing spondylitis
    • Ball J. The enthesopathy of ankylosing spondylitis. Br J Rheumatol 1983;22(4 Suppl. 2):25-8.
    • (1983) Br J Rheumatol , vol.22 , Issue.4 , pp. 25-28
    • Ball, J.1
  • 35
    • 0015061356 scopus 로고
    • Enthesopathy of rheumatoid and ankylosing spondylitis
    • Ball J. Enthesopathy of rheumatoid and ankylosing spondylitis. Ann Rheum Dis 1971;30(3):213-23.
    • (1971) Ann Rheum Dis , vol.30 , Issue.3 , pp. 213-223
    • Ball, J.1
  • 36
    • 0032480614 scopus 로고    scopus 로고
    • Classification of inflammatory arthritis by enthesitis
    • McGonagle D, Gibbon W, Emery P. Classification of inflammatory arthritis by enthesitis. Lancet 1998;352(9134): 1137-40.
    • (1998) Lancet , vol.352 , Issue.9134 , pp. 1137-1140
    • McGonagle, D.1    Gibbon, W.2    Emery, P.3
  • 37
    • 34547805510 scopus 로고    scopus 로고
    • The concept of a "synovio-entheseal complex" and its implications for understanding joint inflammation and damage in psoriatic arthritis and beyond
    • McGonagle D, Lories RJ, Tan AL, et al. The concept of a "synovio-entheseal complex" and its implications for understanding joint inflammation and damage in psoriatic arthritis and beyond. Arthritis Rheum 2007;56(8):2482-91.
    • (2007) Arthritis Rheum , vol.56 , Issue.8 , pp. 2482-2491
    • McGonagle, D.1    Lories, R.J.2    Tan, A.L.3
  • 38
    • 84871797995 scopus 로고    scopus 로고
    • Spondyloarthritides: Related but distinct conditions or a single disease with a heterogeneous phenotype?
    • Jan;
    • Baeten D, Breban M, Lories R, et al. Spondyloarthritides: related but distinct conditions or a single disease with a heterogeneous phenotype? Arthritis Rheum 2013 Jan;65(1):12-20.
    • (2013) Arthritis Rheum , vol.65 , Issue.1 , pp. 12-20
    • Baeten, D.1    Breban, M.2    Lories, R.3
  • 39
    • 71249158763 scopus 로고    scopus 로고
    • Differences in pathophysiology between rheumatoid arthritis and ankylosing spondylitis
    • Lories RJ, Baeten DL. Differences in pathophysiology between rheumatoid arthritis and ankylosing spondylitis. Clin Exp Rheumatol 2009;27(4 Suppl. 55):S10-4.
    • (2009) Clin Exp Rheumatol , vol.27 , Issue.4 , pp. S10-S14
    • Lories, R.J.1    Baeten, D.L.2
  • 40
    • 0035154270 scopus 로고    scopus 로고
    • Human periosteum-derived cells maintain phenotypic stability and chondrogenic potential throughout expansion regardless of donor age
    • De Bari C, Dell'Accio F, Luyten FP. Human periosteum-derived cells maintain phenotypic stability and chondrogenic potential throughout expansion regardless of donor age. Arthritis Rheum 2001;44(1):85-95.
    • (2001) Arthritis Rheum , vol.44 , Issue.1 , pp. 85-95
    • De Bari, C.1    Dell'Accio, F.2    Luyten, F.P.3
  • 41
    • 0034881402 scopus 로고    scopus 로고
    • Multipotent mesenchymal stem cells from adult human synovial membrane
    • De Bari C, Dell'Accio F, Tylzanowski P, et al. Multipotent mesenchymal stem cells from adult human synovial membrane. Arthritis Rheum 2001;44(8):1928-42.
    • (2001) Arthritis Rheum , vol.44 , Issue.8 , pp. 1928-1942
    • De Bari, C.1    Dell'Accio, F.2    Tylzanowski, P.3
  • 42
    • 33646358697 scopus 로고    scopus 로고
    • Mesenchymal multipotency of adult human periosteal cells demonstrated by single-cell lineage analysis
    • De Bari C, Dell'Accio F, Vanlauwe J, et al. Mesenchymal multipotency of adult human periosteal cells demonstrated by single-cell lineage analysis. Arthritis Rheum 2006;54(4):1209-21.
    • (2006) Arthritis Rheum , vol.54 , Issue.4 , pp. 1209-1221
    • De Bari, C.1    Dell'Accio, F.2    Vanlauwe, J.3
  • 43
    • 0033679672 scopus 로고    scopus 로고
    • Mesenchymal cells expressing bone morphogenetic protein receptors are present in the rheumatoid arthritis joint
    • Marinova-Mutafchieva L, Taylor P, Funa K, et al. Mesenchymal cells expressing bone morphogenetic protein receptors are present in the rheumatoid arthritis joint. Arthritis Rheum 2000;43(9):2046-55.
    • (2000) Arthritis Rheum , vol.43 , Issue.9 , pp. 2046-2055
    • Marinova-Mutafchieva, L.1    Taylor, P.2    Funa, K.3
  • 44
    • 84926248988 scopus 로고    scopus 로고
    • Role of vascular channels as a novel mechanism for subchondral bone damage at cruciate ligament entheses in osteoarthritis and inflammatory arthritis
    • [in press]
    • Binks DA, Gravallese EM, Bergin D, et al. Role of vascular channels as a novel mechanism for subchondral bone damage at cruciate ligament entheses in osteoarthritis and inflammatory arthritis. Ann Rheum Dis 2013 [in press].
    • (2013) Ann Rheum Dis
    • Binks, D.A.1    Gravallese, E.M.2    Bergin, D.3
  • 45
    • 0020471717 scopus 로고
    • Some pathological features of ankylosing spondylitis as revealed by microradiography and tetracycline labelling
    • Francois RJ. Some pathological features of ankylosing spondylitis as revealed by microradiography and tetracycline labelling. Clin Rheumatol 1982;1(1):23-9.
    • (1982) Clin Rheumatol , vol.1 , Issue.1 , pp. 23-29
    • Francois, R.J.1
  • 46
    • 0033694989 scopus 로고    scopus 로고
    • Histopathologic evidence that sacroiliitis in ankylosing spondylitis is not merely enthesitis
    • Francois RJ, Gardner DL, Degrave EJ, et al. Histopathologic evidence that sacroiliitis in ankylosing spondylitis is not merely enthesitis. Arthritis Rheum 2000;43(9):2011-24.
    • (2000) Arthritis Rheum , vol.43 , Issue.9 , pp. 2011-2024
    • Francois, R.J.1    Gardner, D.L.2    Degrave, E.J.3
  • 47
    • 33745055952 scopus 로고    scopus 로고
    • Immunohistochemical analysis of hip arthritis in ankylosing spondylitis: Evaluation of the bone-cartilage interface and subchondral bone marrow
    • Appel H, Kuhne M, Spiekermann S, et al. Immunohistochemical analysis of hip arthritis in ankylosing spondylitis: evaluation of the bone-cartilage interface and subchondral bone marrow. Arthritis Rheum 2006;54(6):1805-13.
    • (2006) Arthritis Rheum , vol.54 , Issue.6 , pp. 1805-1813
    • Appel, H.1    Kuhne, M.2    Spiekermann, S.3
  • 48
    • 70249111818 scopus 로고    scopus 로고
    • Correlation of histopathological findings and magnetic resonance imaging in the spine of patients with ankylosing spondylitis
    • Appel H, Loddenkemper C, Grozdanovic Z, et al. Correlation of histopathological findings and magnetic resonance imaging in the spine of patients with ankylosing spondylitis. Arthritis Res Ther 2006;8(5):R143.
    • (2006) Arthritis Res Ther , vol.8 , Issue.5 , pp. R143
    • Appel, H.1    Loddenkemper, C.2    Grozdanovic, Z.3
  • 49
    • 77950641223 scopus 로고    scopus 로고
    • Immunohistochemical analysis of osteoblasts in zygapophyseal joints of patients with ankylosing spondylitis reveal repair mechanisms similar to osteoarthritis
    • Appel H, Maier R, Loddenkemper C, et al. Immunohistochemical analysis of osteoblasts in zygapophyseal joints of patients with ankylosing spondylitis reveal repair mechanisms similar to osteoarthritis. J Rheumatol 2010;37(4): 823-8.
    • (2010) J Rheumatol , vol.37 , Issue.4 , pp. 823-828
    • Appel, H.1    Maier, R.2    Loddenkemper, C.3
  • 50
    • 1942532044 scopus 로고    scopus 로고
    • Ankylosing enthesitis, dactylitis, and onychoperiostitis in male DBA/1 mice: A model of psoriatic arthritis
    • Lories RJ, Matthys P, de Vlam K, et al. Ankylosing enthesitis, dactylitis, and onychoperiostitis in male DBA/1 mice: a model of psoriatic arthritis. Ann Rheum Dis 2004;63(5):595-8.
    • (2004) Ann Rheum Dis , vol.63 , Issue.5 , pp. 595-598
    • Lories, R.J.1    Matthys, P.2    De Vlam, K.3
  • 52
    • 82955233020 scopus 로고    scopus 로고
    • The balance of tissue repair and remodeling in chronic arthritis
    • Lories R. The balance of tissue repair and remodeling in chronic arthritis. Nat Rev Rheumatol 2011;7(12):700-7.
    • (2011) Nat Rev Rheumatol , vol.7 , Issue.12 , pp. 700-707
    • Lories, R.1
  • 53
    • 84867836732 scopus 로고    scopus 로고
    • Pathophysiology of new bone formation and ankylosis in spondyloarthritis
    • Lories RJ, Schett G. Pathophysiology of new bone formation and ankylosis in spondyloarthritis. Rheum Dis Clin N Am 2012;38(3):555-67.
    • (2012) Rheum Dis Clin N Am , vol.38 , Issue.3 , pp. 555-567
    • Lories, R.J.1    Schett, G.2
  • 54
    • 20444478272 scopus 로고    scopus 로고
    • Modulation of bone morphogenetic protein signaling inhibits the onset and progression of ankylosing enthesitis
    • Lories RJ, Derese I, Luyten FP. Modulation of bone morphogenetic protein signaling inhibits the onset and progression of ankylosing enthesitis. J Clin Invest 2005;115(6):1571-9.
    • (2005) J Clin Invest , vol.115 , Issue.6 , pp. 1571-1579
    • Lories, R.J.1    Derese, I.2    Luyten, F.P.3
  • 55
    • 33846949349 scopus 로고    scopus 로고
    • Dickkopf-1 is a master regulator of joint remodeling
    • Diarra D, Stolina M, Polzer K, et al. Dickkopf-1 is a master regulator of joint remodeling. Nat Med 2007;13(2):156-63.
    • (2007) Nat Med , vol.13 , Issue.2 , pp. 156-163
    • Diarra, D.1    Stolina, M.2    Polzer, K.3
  • 56
    • 77949473288 scopus 로고    scopus 로고
    • Blockade of Dickkopf (DKK)-1 induces fusion of sacroiliac joints
    • Uderhardt S, Diarra D, Katzenbeisser J, et al. Blockade of Dickkopf (DKK)-1 induces fusion of sacroiliac joints. Ann Rheum Dis 2010;69(3):592-7.
    • (2010) Ann Rheum Dis , vol.69 , Issue.3 , pp. 592-597
    • Uderhardt, S.1    Diarra, D.2    Katzenbeisser, J.3
  • 57
    • 84857232095 scopus 로고    scopus 로고
    • Blockade of the hedgehog pathway inhibits osteophyte formation in arthritis
    • Ruiz-Heiland G, Horn A, Zerr P, et al. Blockade of the hedgehog pathway inhibits osteophyte formation in arthritis. Ann Rheum Dis 2012;71(3):400-7.
    • (2012) Ann Rheum Dis , vol.71 , Issue.3 , pp. 400-407
    • Ruiz-Heiland, G.1    Horn, A.2    Zerr, P.3
  • 58
    • 45549083413 scopus 로고    scopus 로고
    • Relationship of bone morphogenetic proteins to disease activity and radiographic damage in patients with ankylosing spondylitis
    • Park MC, Park YB, Lee SK. Relationship of bone morphogenetic proteins to disease activity and radiographic damage in patients with ankylosing spondylitis. Scand J Rheumatol 2008;37(3):200-4.
    • (2008) Scand J Rheumatol , vol.37 , Issue.3 , pp. 200-204
    • Park, M.C.1    Park, Y.B.2    Lee, S.K.3
  • 59
    • 76649092609 scopus 로고    scopus 로고
    • Peripheral blood expression profiles of bone morphogenetic proteins, tumor necrosis factor-superfamily molecules, and transcription factor Runx2 could be used as markers of the form of arthritis, disease activity, and therapeutic responsiveness
    • Grcevic D, Jajic Z, Kovacic N, et al. Peripheral blood expression profiles of bone morphogenetic proteins, tumor necrosis factor-superfamily molecules, and transcription factor Runx2 could be used as markers of the form of arthritis, disease activity, and therapeutic responsiveness. J Rheumatol 2010;37(2):246-56.
    • (2010) J Rheumatol , vol.37 , Issue.2 , pp. 246-256
    • Grcevic, D.1    Jajic, Z.2    Kovacic, N.3
  • 60
    • 77957885722 scopus 로고    scopus 로고
    • Association of bone morphogenetic proteins with spinal fusion in ankylosing spondylitis
    • Chen HA, Chen CH, Lin YJ, et al. Association of bone morphogenetic proteins with spinal fusion in ankylosing spondylitis. J Rheumatol 2010;37(10):2126-32.
    • (2010) J Rheumatol , vol.37 , Issue.10 , pp. 2126-2132
    • Chen, H.A.1    Chen, C.H.2    Lin, Y.J.3
  • 61
    • 84892986448 scopus 로고    scopus 로고
    • Effect of tumour necrosis factor-alpha inhibitor on serum level of dickkopf- 1 protein and bone morphogenetic protein-7 in ankylosing spondylitis patients with high disease activity
    • Korkosz M, Gasowski J, Leszczynski P, et al. Effect of tumour necrosis factor-alpha inhibitor on serum level of dickkopf- 1 protein and bone morphogenetic protein-7 in ankylosing spondylitis patients with high disease activity. Scand J Rheumatol 2014;43(1):43-8.
    • (2014) Scand J Rheumatol , vol.43 , Issue.1 , pp. 43-48
    • Korkosz, M.1    Gasowski, J.2    Leszczynski, P.3
  • 62
    • 74849091356 scopus 로고    scopus 로고
    • Evidence that Dkk-1 is dysfunctional in ankylosing spondylitis
    • Daoussis D, Liossis SN, Solomou EE, et al. Evidence that Dkk-1 is dysfunctional in ankylosing spondylitis. Arthritis Rheum 2010;62(1):150-8.
    • (2010) Arthritis Rheum , vol.62 , Issue.1 , pp. 150-158
    • Daoussis, D.1    Liossis, S.N.2    Solomou, E.E.3
  • 63
    • 84866791414 scopus 로고    scopus 로고
    • Biomarkers and cytokines of bone turnover: Extensive evaluation in a cohort of patients with ankylosing spondylitis
    • Taylan A, Sari I, Akinci B, et al. Biomarkers and cytokines of bone turnover: extensive evaluation in a cohort of patients with ankylosing spondylitis. BMC Musculoskelet Disord 2012;13:191.
    • (2012) BMC Musculoskelet Disord , vol.13 , pp. 191
    • Taylan, A.1    Sari, I.2    Akinci, B.3
  • 64
    • 84903700269 scopus 로고    scopus 로고
    • Biomarkers of bone metabolism in ankylosing spondylitis in relation to osteoproliferation and osteoporosis
    • Klingberg E, Nurkkala M, Carlsten H, et al. Biomarkers of bone metabolism in ankylosing spondylitis in relation to osteoproliferation and osteoporosis. J Rheumatol 2014;41(7):1349-56.
    • (2014) J Rheumatol , vol.41 , Issue.7 , pp. 1349-1356
    • Klingberg, E.1    Nurkkala, M.2    Carlsten, H.3
  • 65
    • 70350558488 scopus 로고    scopus 로고
    • Altered skeletal expression of sclerostin and its link to radiographic progression in ankylosing spondylitis
    • Appel H, Ruiz-Heiland G, Listing J, et al. Altered skeletal expression of sclerostin and its link to radiographic progression in ankylosing spondylitis. Arthritis Rheum 2009;60(11):3257-62.
    • (2009) Arthritis Rheum , vol.60 , Issue.11 , pp. 3257-3262
    • Appel, H.1    Ruiz-Heiland, G.2    Listing, J.3
  • 66
    • 84857910076 scopus 로고    scopus 로고
    • High level of functional dickkopf-1 predicts protection from syndesmophyte formation in patients with ankylosing spondylitis
    • Heiland GR, Appel H, Poddubnyy D, et al. High level of functional dickkopf-1 predicts protection from syndesmophyte formation in patients with ankylosing spondylitis. Ann Rheum Dis 2012;71(4):572-4.
    • (2012) Ann Rheum Dis , vol.71 , Issue.4 , pp. 572-574
    • Heiland, G.R.1    Appel, H.2    Poddubnyy, D.3
  • 67
    • 76649094260 scopus 로고    scopus 로고
    • Disease modification in ankylosing spondylitis
    • Maksymowych WP. Disease modification in ankylosing spondylitis. Nat Rev Rheumatol 2010;6(2):75-81.
    • (2010) Nat Rev Rheumatol , vol.6 , Issue.2 , pp. 75-81
    • Maksymowych, W.P.1
  • 68
    • 84861837660 scopus 로고    scopus 로고
    • Motion for debate: The development of ankylosis in ankylosing spondylitis is largely dependent on inflammation
    • Maksymowych WP, Elewaut D, Schett G. Motion for debate: the development of ankylosis in ankylosing spondylitis is largely dependent on inflammation. Arthritis Rheum 2012;64(6):1713-9.
    • (2012) Arthritis Rheum , vol.64 , Issue.6 , pp. 1713-1719
    • Maksymowych, W.P.1    Elewaut, D.2    Schett, G.3
  • 69
    • 78049439518 scopus 로고    scopus 로고
    • Are current available therapies disease-modifying in spondyloarthritis?
    • Lories RJ, de Vlam K, Luyten FP. Are current available therapies disease-modifying in spondyloarthritis? Best Pract Res Clin Rheumatol 2010;24(5):625-35.
    • (2010) Best Pract Res Clin Rheumatol , vol.24 , Issue.5 , pp. 625-635
    • Lories, R.J.1    De Vlam, K.2    Luyten, F.P.3
  • 70
    • 84857198386 scopus 로고    scopus 로고
    • Inflammation and ankylosis: Still an enigmatic relationship in spondyloarthritis
    • Lories RJ, Dougados M. Inflammation and ankylosis: still an enigmatic relationship in spondyloarthritis. Ann Rheum Dis 2012;71(3):317-8.
    • (2012) Ann Rheum Dis , vol.71 , Issue.3 , pp. 317-318
    • Lories, R.J.1    Dougados, M.2
  • 71
    • 54949113223 scopus 로고    scopus 로고
    • Radiographic findings following two years of infliximab therapy in patients with ankylosing spondylitis
    • van der Heijde D, Landewe R, Baraliakos X, et al. Radiographic findings following two years of infliximab therapy in patients with ankylosing spondylitis. Arthritis Rheum 2008;58(10):3063-70.
    • (2008) Arthritis Rheum , vol.58 , Issue.10 , pp. 3063-3070
    • Van Der Heijde, D.1    Landewe, R.2    Baraliakos, X.3
  • 72
    • 43949140512 scopus 로고    scopus 로고
    • Radiographic progression of ankylosing spondylitis after up to two years of treatment with etanercept
    • van der Heijde D, Landewe R, Einstein S, et al. Radiographic progression of ankylosing spondylitis after up to two years of treatment with etanercept. Arthritis Rheum 2008;58(5):1324-31.
    • (2008) Arthritis Rheum , vol.58 , Issue.5 , pp. 1324-1331
    • Van Der Heijde, D.1    Landewe, R.2    Einstein, S.3
  • 73
    • 73349110978 scopus 로고    scopus 로고
    • Assessment of radiographic progression in the spines of patients with ankylosing spondylitis treated with adalimumab for up to 2 years
    • van der Heijde D, Salonen D, Weissman BN, et al. Assessment of radiographic progression in the spines of patients with ankylosing spondylitis treated with adalimumab for up to 2 years. Arthritis Res Ther 2009;11(4):R127.
    • (2009) Arthritis Res Ther , vol.11 , Issue.4 , pp. R127
    • Van Der Heijde, D.1    Salonen, D.2    Weissman, B.N.3
  • 74
    • 33847077596 scopus 로고    scopus 로고
    • Evidence for uncoupling of inflammation and joint remodeling in a mouse model of spondylarthritis
    • Lories RJ, Derese I, de Bari C, et al. Evidence for uncoupling of inflammation and joint remodeling in a mouse model of spondylarthritis. Arthritis Rheum 2007;56(2):489-97.
    • (2007) Arthritis Rheum , vol.56 , Issue.2 , pp. 489-497
    • Lories, R.J.1    Derese, I.2    De Bari, C.3
  • 75
    • 42949084641 scopus 로고    scopus 로고
    • Inhibition of osteoclasts does not prevent joint ankylosis in a mouse model of spondyloarthritis
    • Lories RJ, Derese I, Luyten FP. Inhibition of osteoclasts does not prevent joint ankylosis in a mouse model of spondyloarthritis. Rheumatol (Oxford) 2008;47(5):605-8.
    • (2008) Rheumatol (Oxford) , vol.47 , Issue.5 , pp. 605-608
    • Lories, R.J.1    Derese, I.2    Luyten, F.P.3
  • 76
    • 84885126123 scopus 로고    scopus 로고
    • The impact of tumor necrosis factor alpha inhibitors on radiographic progression in ankylosing spondylitis
    • Haroon N, Inman RD, Learch TJ, et al. The impact of tumor necrosis factor alpha inhibitors on radiographic progression in ankylosing spondylitis. Arthritis Rheum 2013;65(10):2645-54.
    • (2013) Arthritis Rheum , vol.65 , Issue.10 , pp. 2645-2654
    • Haroon, N.1    Inman, R.D.2    Learch, T.J.3
  • 77
    • 40549109246 scopus 로고    scopus 로고
    • Critical appraisal of assessment of structural damage in ankylosing spondylitis: Implications for treatment outcomes
    • Sieper J, Appel H, Braun J, et al. Critical appraisal of assessment of structural damage in ankylosing spondylitis: implications for treatment outcomes. Arthritis Rheum 2008;58(3):649-56.
    • (2008) Arthritis Rheum , vol.58 , Issue.3 , pp. 649-656
    • Sieper, J.1    Appel, H.2    Braun, J.3
  • 78
    • 67651154370 scopus 로고    scopus 로고
    • Progress in spondylarthritis. Mechanisms of new bone formation in spondyloarthritis
    • Lories RJ, Luyten FP, de Vlam K. Progress in spondylarthritis. Mechanisms of new bone formation in spondyloarthritis. Arthritis Res Ther 2009;11(2):221.
    • (2009) Arthritis Res Ther , vol.11 , Issue.2 , pp. 221
    • Lories, R.J.1    Luyten, F.P.2    De Vlam, K.3
  • 79
    • 84863697312 scopus 로고    scopus 로고
    • IL-23 induces spondyloarthropathy by acting on ROR-gammat(+) CD3(+) CD4(+)CD8(+) entheseal resident T cells
    • Sherlock JP, Joyce-Shaikh B, Turner SP, et al. IL-23 induces spondyloarthropathy by acting on ROR-gammat(+) CD3(+) CD4(+)CD8(+) entheseal resident T cells. Nat Med 2012;18(7):1069-76.
    • (2012) Nat Med , vol.18 , Issue.7 , pp. 1069-1076
    • Sherlock, J.P.1    Joyce-Shaikh, B.2    Turner, S.P.3
  • 80
    • 84863669568 scopus 로고    scopus 로고
    • Primed for inflammation: Enthesis-resident T cells
    • Lories RJ, McInnes IB. Primed for inflammation: enthesis-resident T cells. Nat Med 2012;18(7):1018-9.
    • (2012) Nat Med , vol.18 , Issue.7 , pp. 1018-1019
    • Lories, R.J.1    McInnes, I.B.2
  • 81
    • 73249153202 scopus 로고    scopus 로고
    • From HLA-B27 to spondyloarthritis: A journey through the ER
    • Colbert RA, DeLay ML, Klenk EI, et al. From HLA-B27 to spondyloarthritis: a journey through the ER. Immunol Rev 2010;233(1):181-202.
    • (2010) Immunol Rev , vol.233 , Issue.1 , pp. 181-202
    • Colbert, R.A.1    Delay, M.L.2    Klenk, E.I.3
  • 82
    • 69449086287 scopus 로고    scopus 로고
    • HLA-B27 misfolding and the unfolded protein response augment interleukin-23 production and are associated with Th17 activation in transgenic rats
    • DeLay ML, Turner MJ, Klenk EI, et al. HLA-B27 misfolding and the unfolded protein response augment interleukin-23 production and are associated with Th17 activation in transgenic rats. Arthritis Rheum 2009;60(9):2633-43.
    • (2009) Arthritis Rheum , vol.60 , Issue.9 , pp. 2633-2643
    • Delay, M.L.1    Turner, M.J.2    Klenk, E.I.3
  • 83
    • 33846194065 scopus 로고    scopus 로고
    • HLA-B27 up-regulation causes accumulation of misfolded heavy chains and correlates with the magnitude of the unfolded protein response in transgenic rats: Implications for the pathogenesis of spondylarthritis-like disease
    • Turner MJ, Delay ML, Bai S, et al. HLA-B27 up-regulation causes accumulation of misfolded heavy chains and correlates with the magnitude of the unfolded protein response in transgenic rats: implications for the pathogenesis of spondylarthritis-like disease. Arthritis Rheum 2007;56(1):215-23.
    • (2007) Arthritis Rheum , vol.56 , Issue.1 , pp. 215-223
    • Turner, M.J.1    Delay, M.L.2    Bai, S.3
  • 84
    • 23444431837 scopus 로고    scopus 로고
    • HLA-B27 misfolding in transgenic rats is associated with activation of the unfolded protein response
    • Turner MJ, Sowders DP, DeLay ML, et al. HLA-B27 misfolding in transgenic rats is associated with activation of the unfolded protein response. J Immunol 2005;175(4):2438-48.
    • (2005) J Immunol , vol.175 , Issue.4 , pp. 2438-2448
    • Turner, M.J.1    Sowders, D.P.2    Delay, M.L.3
  • 85
    • 84903907928 scopus 로고    scopus 로고
    • Evidence that autophagy but not the unfolded protein response regulates the expression of IL-23 in the gut of patients with ankylosing spondylitis and subclinical gut inflammation
    • Aug;
    • Ciccia F, Accardo-Palumbo A, Rizzo A, et al. Evidence that autophagy, but not the unfolded protein response, regulates the expression of IL-23 in the gut of patients with ankylosing spondylitis and subclinical gut inflammation. Ann Rheum Dis 2013 Aug;73(8):1566-74. http://dx.doi.org/10.1136/annrheumdis-2012-202925.
    • (2013) Ann Rheum Dis , vol.73 , Issue.8 , pp. 1566-1574
    • Ciccia, F.1    Accardo-Palumbo, A.2    Rizzo, A.3
  • 86
    • 84893817150 scopus 로고    scopus 로고
    • No evidence for a critical role of the unfolded protein response in synovium and blood of patients with ankylosing spondylitis
    • Neerinckx B, Carter S, Lories RJ. No evidence for a critical role of the unfolded protein response in synovium and blood of patients with ankylosing spondylitis. Ann Rheum Dis 2014;73(3):629-30.
    • (2014) Ann Rheum Dis , vol.73 , Issue.3 , pp. 629-630
    • Neerinckx, B.1    Carter, S.2    Lories, R.J.3
  • 87
    • 0021816009 scopus 로고
    • HLA-B27 related arthritis and bowel inflammation. Part 2. Ileocolonoscopy and bowel histology in patients with HLA-B27 related arthritis
    • Mielants H, Veys EM, Cuvelier C, et al. HLA-B27 related arthritis and bowel inflammation. Part 2. Ileocolonoscopy and bowel histology in patients with HLA-B27 related arthritis. J Rheumatol 1985;12(2):294-8.
    • (1985) J Rheumatol , vol.12 , Issue.2 , pp. 294-298
    • Mielants, H.1    Veys, E.M.2    Cuvelier, C.3
  • 88
    • 84873725322 scopus 로고    scopus 로고
    • Microscopic gut inflammation in axial spondyloarthritis: A multiparametric predictive model
    • Van Praet L, Van den Bosch FE, Jacques P, et al. Microscopic gut inflammation in axial spondyloarthritis: a multiparametric predictive model. Ann Rheum Dis 2013;72(3):414-7.
    • (2013) Ann Rheum Dis , vol.72 , Issue.3 , pp. 414-417
    • Van Praet, L.1    Van Den Bosch, F.E.2    Jacques, P.3
  • 89
    • 70349564251 scopus 로고    scopus 로고
    • The enthesis organ concept and its relevance to the spondyloarthropathies
    • Benjamin M, McGonagle D. The enthesis organ concept and its relevance to the spondyloarthropathies. Adv Exp Med Biol 2009;649:57-70.
    • (2009) Adv Exp Med Biol , vol.649 , pp. 57-70
    • Benjamin, M.1    McGonagle, D.2
  • 90
    • 84891747499 scopus 로고    scopus 로고
    • Proof of concept: Enthesitis and new bone formation in spondyloarthritis are driven by mechanical strain and stromal cells
    • Jacques P, Lambrecht S, Verheugen E, et al. Proof of concept: enthesitis and new bone formation in spondyloarthritis are driven by mechanical strain and stromal cells. Ann Rheum Dis 2014;73(2):437-45.
    • (2014) Ann Rheum Dis , vol.73 , Issue.2 , pp. 437-445
    • Jacques, P.1    Lambrecht, S.2    Verheugen, E.3
  • 91
    • 84903848853 scopus 로고    scopus 로고
    • Higher disease activity leads to more structural damage in the spine in ankylosing spondylitis: 12-year longitudinal data from the OASIS cohort
    • Ramiro S, van der Heijde D, van Tubergen A, et al. Higher disease activity leads to more structural damage in the spine in ankylosing spondylitis: 12-year longitudinal data from the OASIS cohort. Ann Rheum Dis 2014;73(8):1455-61.
    • (2014) Ann Rheum Dis , vol.73 , Issue.8 , pp. 1455-1461
    • Ramiro, S.1    Van Der Heijde, D.2    Van Tubergen, A.3
  • 92
    • 58249103888 scopus 로고    scopus 로고
    • Inflammatory lesions of the spine on magnetic resonance imaging predict the development of new syndesmophytes in ankylosing spondylitis: Evidence of a relationship between inflammation and new bone formation
    • Maksymowych WP, Chiowchanwisawakit P, Clare T, et al. Inflammatory lesions of the spine on magnetic resonance imaging predict the development of new syndesmophytes in ankylosing spondylitis: evidence of a relationship between inflammation and new bone formation. Arthritis Rheum 2009;60(1):93-102.
    • (2009) Arthritis Rheum , vol.60 , Issue.1 , pp. 93-102
    • Maksymowych, W.P.1    Chiowchanwisawakit, P.2    Clare, T.3
  • 93
    • 52249096602 scopus 로고    scopus 로고
    • The relationship between inflammation and new bone formation in patients with ankylosing spondylitis
    • Baraliakos X, Listing J, Rudwaleit M, et al. The relationship between inflammation and new bone formation in patients with ankylosing spondylitis. Arthritis Res Ther 2008;10(5):R104.
    • (2008) Arthritis Res Ther , vol.10 , Issue.5 , pp. R104
    • Baraliakos, X.1    Listing, J.2    Rudwaleit, M.3
  • 94
    • 84857211345 scopus 로고    scopus 로고
    • MRI inflammation at the vertebral unit only marginally predicts new syndesmophyte formation: A multilevel analysis in patients with ankylosing spondylitis
    • van der Heijde D, Machado P, Braun J, et al. MRI inflammation at the vertebral unit only marginally predicts new syndesmophyte formation: a multilevel analysis in patients with ankylosing spondylitis. Ann Rheum Dis 2012;71(3): 369-73.
    • (2012) Ann Rheum Dis , vol.71 , Issue.3 , pp. 369-373
    • Van Der Heijde, D.1    Machado, P.2    Braun, J.3
  • 95
    • 79961100171 scopus 로고    scopus 로고
    • Focal fat lesions at vertebral corners on magnetic resonance imaging predict the development of new syndesmophytes in ankylosing spondylitis
    • Chiowchanwisawakit P, Lambert RG, Conner-Spady B, et al. Focal fat lesions at vertebral corners on magnetic resonance imaging predict the development of new syndesmophytes in ankylosing spondylitis. Arthritis Rheum 2011; 63(8):2215-25.
    • (2011) Arthritis Rheum , vol.63 , Issue.8 , pp. 2215-2225
    • Chiowchanwisawakit, P.1    Lambert, R.G.2    Conner-Spady, B.3
  • 96
    • 79959948424 scopus 로고    scopus 로고
    • Resolution of inflammation following treatment of ankylosing spondylitis is associated with new bone formation
    • Pedersen SJ, Chiowchanwisawakit P, Lambert RG, et al. Resolution of inflammation following treatment of ankylosing spondylitis is associated with new bone formation. J Rheumatol 2011;38(7):1349-54.
    • (2011) J Rheumatol , vol.38 , Issue.7 , pp. 1349-1354
    • Pedersen, S.J.1    Chiowchanwisawakit, P.2    Lambert, R.G.3
  • 97
    • 85027939037 scopus 로고    scopus 로고
    • Suppression of inflammation and effects on new bone formation in ankylosing spondylitis: Evidence for a window of opportunity in disease modification
    • Maksymowych WP, Morency N, Conner-Spady B, et al. Suppression of inflammation and effects on new bone formation in ankylosing spondylitis: evidence for a window of opportunity in disease modification. Ann Rheum Dis 2013; 72(1):23-8.
    • (2013) Ann Rheum Dis , vol.72 , Issue.1 , pp. 23-28
    • Maksymowych, W.P.1    Morency, N.2    Conner-Spady, B.3
  • 98
    • 57349171954 scopus 로고    scopus 로고
    • BMP type i receptor inhibition reduces heterotopic [corrected] ossification
    • Yu PB, Deng DY, Lai CS, et al. BMP type I receptor inhibition reduces heterotopic [corrected] ossification. Nat Med 2008;14(12):1363-9.
    • (2008) Nat Med , vol.14 , Issue.12 , pp. 1363-1369
    • Yu, P.B.1    Deng, D.Y.2    Lai, C.S.3
  • 99
    • 84857990743 scopus 로고    scopus 로고
    • Inhibition of inflammation but not ankylosis by glucocorticoids in mice: Further evidence for the entheseal stress hypothesis
    • Braem K, Deroose CM, Luyten FP, et al. Inhibition of inflammation but not ankylosis by glucocorticoids in mice: further evidence for the entheseal stress hypothesis. Arthritis Res Ther 2012;14(2):R59.
    • (2012) Arthritis Res Ther , vol.14 , Issue.2 , pp. R59
    • Braem, K.1    Deroose, C.M.2    Luyten, F.P.3
  • 100
    • 84906991087 scopus 로고    scopus 로고
    • Serum levels of novel noggin and sclerostin-immune complexes are elevated in ankylosing spondylitis
    • Oct
    • Tsui FW, Tsui HW, Las Heras F, et al. Serum levels of novel noggin and sclerostin-immune complexes are elevated in ankylosing spondylitis. Ann Rheum Dis 2013 Oct;73(10):1873-9. http://dx.doi.org/10.1136/annrheumdis-2013- 203630.
    • (2013) Ann Rheum Dis , vol.73 , Issue.10 , pp. 1873-1879
    • Tsui, F.W.1    Tsui, H.W.2    Las Heras, F.3
  • 101
    • 0017265072 scopus 로고
    • Retardation of ossification of the lumbar vertebral column in ankylosing spondylitis by means of phenylbutazone
    • Boersma JW. Retardation of ossification of the lumbar vertebral column in ankylosing spondylitis by means of phenylbutazone. Scand J Rheumatol 1976;5(1):60-4.
    • (1976) Scand J Rheumatol , vol.5 , Issue.1 , pp. 60-64
    • Boersma, J.W.1
  • 102
    • 20744445686 scopus 로고    scopus 로고
    • Nonsteroidal antiinflammatory drugs reduce radiographic progression in patients with ankylosing spondylitis: A randomized clinical trial
    • Wanders A, Heijde D, Landewe R, et al. Nonsteroidal antiinflammatory drugs reduce radiographic progression in patients with ankylosing spondylitis: a randomized clinical trial. Arthritis Rheum 2005;52(6):1756-65.
    • (2005) Arthritis Rheum , vol.52 , Issue.6 , pp. 1756-1765
    • Wanders, A.1    Heijde, D.2    Landewe, R.3
  • 103
    • 85027933537 scopus 로고    scopus 로고
    • Continuous NSAID use reverts the effects of inflammation on radiographic progression in patients with ankylosing spondylitis
    • Oct;
    • Kroon F, Landewe R, Dougados M, et al. Continuous NSAID use reverts the effects of inflammation on radiographic progression in patients with ankylosing spondylitis. Ann Rheum Dis 2012 Oct;71(10):1623-9. http://dx.doi.org/10. 1136/annrheumdis-2012-201370.
    • (2012) Ann Rheum Dis , vol.71 , Issue.10 , pp. 1623-1629
    • Kroon, F.1    Landewe, R.2    Dougados, M.3
  • 104
    • 84880136566 scopus 로고    scopus 로고
    • Effect of non-steroidal anti-inflammatory drugs on radiographic spinal progression in patients with axial spondyloarthritis: Results from the German spondyloarthritis inception cohort
    • Aug;
    • Poddubnyy D, Rudwaleit M, Haibel H, et al. Effect of non-steroidal anti-inflammatory drugs on radiographic spinal progression in patients with axial spondyloarthritis: results from the German spondyloarthritis inception cohort. Ann Rheum Dis 2013 Aug;72(8):1430-2. http://dx.doi.org/10.1136/annrheumdis-2012-203148.
    • (2013) Ann Rheum Dis , vol.72 , Issue.8 , pp. 1430-1432
    • Poddubnyy, D.1    Rudwaleit, M.2    Haibel, H.3
  • 105
    • 84895490291 scopus 로고    scopus 로고
    • Continuous long-term anti-TNF therapy does not lead to an increase in the rate of new bone formation over 8 years in patients with ankylosing spondylitis
    • Baraliakos X, Haibel H, Listing J, et al. Continuous long-term anti-TNF therapy does not lead to an increase in the rate of new bone formation over 8 years in patients with ankylosing spondylitis. Ann Rheum Dis 2014;73(4):710-5.
    • (2014) Ann Rheum Dis , vol.73 , Issue.4 , pp. 710-715
    • Baraliakos, X.1    Haibel, H.2    Listing, J.3


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