-
2
-
-
0346860537
-
-
American Psychiatric Association, Washington, D.C
-
American Psychiatric Association (2000) Diagnostic criteria from DSM-IV-TR. American Psychiatric Association, Washington, D.C.
-
(2000)
Diagnostic criteria from DSM-IV-TR
-
-
-
3
-
-
67649106322
-
Effectiveness and cost-effectiveness of policies and programmes to reduce the harm caused by alcohol
-
Anderson P, Chisholm D, Fuhr DC (2009) Effectiveness and cost-effectiveness of policies and programmes to reduce the harm caused by alcohol. Lancet 373: 2234-2246
-
(2009)
Lancet
, vol.373
, pp. 2234-2246
-
-
Anderson, P.1
Chisholm, D.2
Fuhr, D.C.3
-
4
-
-
33745893228
-
The glutamate/GABA-glutamine cycle: Aspects of transport, neurotransmitter homeostasis and ammonia transfer
-
Bak LK, Schousboe A, Waagepetersen HS (2006) The glutamate/GABA-glutamine cycle: aspects of transport, neurotransmitter homeostasis and ammonia transfer. J Neurochem 98: 641-653
-
(2006)
J Neurochem
, vol.98
, pp. 641-653
-
-
Bak, L.K.1
Schousboe, A.2
Waagepetersen, H.S.3
-
5
-
-
33847704911
-
Association of a functional polymorphism in the mu-opioid receptor gene with alcohol response and consumption in male rhesus macaques
-
Barr CS, Schwandt M, Lindell SG, Chen SA, Goldman D, Suomi SJ, Higley JD, Heilig M (2007) Association of a functional polymorphism in the mu-opioid receptor gene with alcohol response and consumption in male rhesus macaques. Arch Gen Psychiatry 64: 369-376
-
(2007)
Arch Gen Psychiatry
, vol.64
, pp. 369-376
-
-
Barr, C.S.1
Schwandt, M.2
Lindell, S.G.3
Chen, S.A.4
Goldman, D.5
Suomi, S.J.6
Higley, J.D.7
Heilig, M.8
-
6
-
-
84988655097
-
A pharmacogenetic determinant of mu-opioid receptor antagonist effects on alcohol reward and consumption: Evidence from humanized mice
-
Bilbao A, Robinson JE, Heilig M, Malanga CJ, Spanagel R, Sommer WH, Thorsell A (2014) A pharmacogenetic determinant of mu-opioid receptor antagonist effects on alcohol reward and consumption: evidence from humanized mice. Biol Psychiatry
-
(2014)
Biol Psychiatry
-
-
Bilbao, A.1
Robinson, J.E.2
Heilig, M.3
Malanga, C.J.4
Spanagel, R.5
Sommer, W.H.6
Thorsell, A.7
-
7
-
-
43949134527
-
A 6-week randomized, placebo-controlled trial of CP-316,311 (a selective CRH1 antagonist) in the treatment of major depression
-
Binneman B, Feltner D, Kolluri S, Shi Y, Qiu R, Stiger T (2008) A 6-week randomized, placebo-controlled trial of CP-316,311 (a selective CRH1 antagonist) in the treatment of major depression. AJ Psychiatry 165: 617-620
-
(2008)
AJ Psychiatry
, vol.165
, pp. 617-620
-
-
Binneman, B.1
Feltner, D.2
Kolluri, S.3
Shi, Y.4
Qiu, R.5
Stiger, T.6
-
8
-
-
0041592759
-
Alcohol promotes dopamine release in the human nucleus accumbens
-
Boileau I, Assaad JM, Pihl RO, Benkelfat C, Leyton M, Diksic M, Tremblay RE, Dagher A (2003) Alcohol promotes dopamine release in the human nucleus accumbens. Synapse 49: 226-231
-
(2003)
Synapse
, vol.49
, pp. 226-231
-
-
Boileau, I.1
Assaad, J.M.2
Pihl, R.O.3
Benkelfat, C.4
Leyton, M.5
Diksic, M.6
Tremblay, R.E.7
Dagher, A.8
-
9
-
-
13144261678
-
Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: Possible implications for opiate addiction
-
Bond C, LaForge KS, Tian M, Melia D, Zhang S, Borg L, Gong J, Schluger J, Strong JA, Leal SM, Tischfield JA, Kreek MJ, Yu L (1998) Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: possible implications for opiate addiction. Proc Natl Acad Sci U S A 95: 9608-9613
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 9608-9613
-
-
Bond, C.1
LaForge, K.S.2
Tian, M.3
Melia, D.4
Zhang, S.5
Borg, L.6
Gong, J.7
Schluger, J.8
Strong, J.A.9
Leal, S.M.10
Tischfield, J.A.11
Kreek, M.J.12
Yu, L.13
-
10
-
-
84897055898
-
Global ethanol-induced enhancements of monoaminergic neurotransmission: A meta-analysis study
-
Brand I, Fliegel S, Spanagel R, Noori HR (2013) Global ethanol-induced enhancements of monoaminergic neurotransmission: a meta-analysis study. Alcohol Clin Exp Res 37: 2048-2057
-
(2013)
Alcohol Clin Exp Res
, vol.37
, pp. 2048-2057
-
-
Brand, I.1
Fliegel, S.2
Spanagel, R.3
Noori, H.R.4
-
11
-
-
84860502340
-
The relationship between impulsive choice and impulsive action: A cross-species translational study
-
Broos N, Schmaal L, Wiskerke J, Kostelijk L, Lam T, Stoop N, Weierink L, Ham J, de Geus EJ, Schoffelmeer AN, van den Brink W, Veltman DJ, de Vries TJ, Pattij T, Goudriaan AE (2012) The relationship between impulsive choice and impulsive action: a cross-species translational study. PLoS ONE 7: e36781
-
(2012)
PLoS ONE
, vol.7
, pp. e36781
-
-
Broos, N.1
Schmaal, L.2
Wiskerke, J.3
Kostelijk, L.4
Lam, T.5
Stoop, N.6
Weierink, L.7
Ham, J.8
de Geus, E.J.9
Schoffelmeer, A.N.10
van den Brink, W.11
Veltman, D.J.12
de Vries, T.J.13
Pattij, T.14
Goudriaan, A.E.15
-
12
-
-
84876788479
-
Resting-state synchrony in short-term versus long-term abstinent alcoholics
-
Camchong J, Stenger VA, Fein G (2013) Resting-state synchrony in short-term versus long-term abstinent alcoholics. Alcohol Clin Exp Res 37: 794-803
-
(2013)
Alcohol Clin Exp Res
, vol.37
, pp. 794-803
-
-
Camchong, J.1
Stenger, V.A.2
Fein, G.3
-
13
-
-
77951854270
-
Genetic sensitivity to the environment: The case of the serotonin transporter gene and its implications for studying complex diseases and traits
-
Caspi A, Hariri AR, Holmes A, Uher R, Moffitt TE (2010) Genetic sensitivity to the environment: the case of the serotonin transporter gene and its implications for studying complex diseases and traits. AJ Psychiatry 167: 509-527
-
(2010)
AJ Psychiatry
, vol.167
, pp. 509-527
-
-
Caspi, A.1
Hariri, A.R.2
Holmes, A.3
Uher, R.4
Moffitt, T.E.5
-
14
-
-
84860257642
-
Association of mu-opioid receptor (OPRM1) gene polymorphism with response to naltrexone in alcohol dependence: A systematic review and meta-analysis
-
Chamorro AJ, Marcos M, Miron-Canelo JA, Pastor I, Gonzalez-Sarmiento R, Laso FJ (2012) Association of mu-opioid receptor (OPRM1) gene polymorphism with response to naltrexone in alcohol dependence: a systematic review and meta-analysis. Addict Biol 17: 505-512
-
(2012)
Addict Biol
, vol.17
, pp. 505-512
-
-
Chamorro, A.J.1
Marcos, M.2
Miron-Canelo, J.A.3
Pastor, I.4
Gonzalez-Sarmiento, R.5
Laso, F.J.6
-
15
-
-
79951963064
-
Awake rat pharmacological magnetic resonance imaging as a translational pharmacodynamic biomarker: Metabotropic glutamate 2/3 agonist modulation of ketamine-induced blood oxygenation level dependence signals
-
Chin CL, Upadhyay J, Marek GJ, Baker SJ, Zhang M, Mezler M, Fox GB, Day M (2011) Awake rat pharmacological magnetic resonance imaging as a translational pharmacodynamic biomarker: metabotropic glutamate 2/3 agonist modulation of ketamine-induced blood oxygenation level dependence signals. J Pharmacol Exp Ther 336: 709-715
-
(2011)
J Pharmacol Exp Ther
, vol.336
, pp. 709-715
-
-
Chin, C.L.1
Upadhyay, J.2
Marek, G.J.3
Baker, S.J.4
Zhang, M.5
Mezler, M.6
Fox, G.B.7
Day, M.8
-
16
-
-
77955512840
-
Suppression of alcohol self-administration and reinstatement of alcohol seeking by melanin-concentrating hormone receptor 1 (MCH1-R) antagonism in Wistar rats
-
Cippitelli A, Karlsson C, Shaw JL, Thorsell A, Gehlert DR, Heilig M (2010) Suppression of alcohol self-administration and reinstatement of alcohol seeking by melanin-concentrating hormone receptor 1 (MCH1-R) antagonism in Wistar rats. Psychopharmacology 211: 367-375
-
(2010)
Psychopharmacology
, vol.211
, pp. 367-375
-
-
Cippitelli, A.1
Karlsson, C.2
Shaw, J.L.3
Thorsell, A.4
Gehlert, D.R.5
Heilig, M.6
-
17
-
-
84881662107
-
Crosswalk between DSM-IV dependence and DSM-5 substance use disorders for opioids, cannabis, cocaine and alcohol
-
Compton WM, Dawson DA, Goldstein RB, Grant BF (2013) Crosswalk between DSM-IV dependence and DSM-5 substance use disorders for opioids, cannabis, cocaine and alcohol. Drug Alcohol Depend 132(1): 387-390
-
(2013)
Drug Alcohol Depend
, vol.132
, Issue.1
, pp. 387-390
-
-
Compton, W.M.1
Dawson, D.A.2
Goldstein, R.B.3
Grant, B.F.4
-
18
-
-
77953525393
-
Multicenter, randomized, double-blind, active comparator and placebo-controlled trial of a corticotropin-releasing factor receptor-1 antagonist in generalized anxiety disorder
-
Coric V, Feldman HH, Oren DA, Shekhar A, Pultz J, Dockens RC, Wu X, Gentile KA, Huang SP, Emison E, Delmonte T, D’Souza BB, Zimbroff DL, Grebb JA, Goddard AW, Stock EG (2010) Multicenter, randomized, double-blind, active comparator and placebo-controlled trial of a corticotropin-releasing factor receptor-1 antagonist in generalized anxiety disorder. Depress Anxiety 27: 417-425
-
(2010)
Depress Anxiety
, vol.27
, pp. 417-425
-
-
Coric, V.1
Feldman, H.H.2
Oren, D.A.3
Shekhar, A.4
Pultz, J.5
Dockens, R.C.6
Wu, X.7
Gentile, K.A.8
Huang, S.P.9
Emison, E.10
Delmonte, T.11
D’Souza, B.B.12
Zimbroff, D.L.13
Grebb, J.A.14
Goddard, A.W.15
Stock, E.G.16
-
19
-
-
21744438800
-
Long-term stability of alcohol and other substance dependence diagnoses and habitual smoking: An evaluation after 5 years
-
Culverhouse R, Bucholz KK, Crowe RR, Hesselbrock V, Nurnberger JI Jr, Porjesz B, Schuckit MA, Reich T, Bierut LJ (2005) Long-term stability of alcohol and other substance dependence diagnoses and habitual smoking: an evaluation after 5 years. Arch Gen Psychiatry 62: 753-760
-
(2005)
Arch Gen Psychiatry
, vol.62
, pp. 753-760
-
-
Culverhouse, R.1
Bucholz, K.K.2
Crowe, R.R.3
Hesselbrock, V.4
Nurnberger, J.I.5
Porjesz, B.6
Schuckit, M.A.7
Reich, T.8
Bierut, L.J.9
-
20
-
-
84930363052
-
Translating intermediate phenotypes to psychopathology: The NIMH research domain criteria
-
Cuthbert BN (2014) Translating intermediate phenotypes to psychopathology: the NIMH research domain criteria. Psychophysiology 51: 1205-1206
-
(2014)
Psychophysiology
, vol.51
, pp. 1205-1206
-
-
Cuthbert, B.N.1
-
21
-
-
0032733053
-
Effect of repeated ethanol withdrawal on glutamate microdialysate in the hippocampus
-
Dahchour A, De Witte P (1999) Effect of repeated ethanol withdrawal on glutamate microdialysate in the hippocampus. Alcohol Clin Exp Res 23: 1698-1703
-
(1999)
Alcohol Clin Exp Res
, vol.23
, pp. 1698-1703
-
-
Dahchour, A.1
De Witte, P.2
-
22
-
-
0032550745
-
Central effects of acamprosate: Part 1. Acamprosate blocks the glutamate increase in the nucleus accumbens microdialysate in ethanol withdrawn rats
-
Dahchour A, De Witte P, Bolo N, Nedelec JF, Muzet M, Durbin P, Macher JP (1998) Central effects of acamprosate: part 1. Acamprosate blocks the glutamate increase in the nucleus accumbens microdialysate in ethanol withdrawn rats. Psychiatry Res 82: 107-114
-
(1998)
Psychiatry Res
, vol.82
, pp. 107-114
-
-
Dahchour, A.1
De Witte, P.2
Bolo, N.3
Nedelec, J.F.4
Muzet, M.5
Durbin, P.6
Macher, J.P.7
-
23
-
-
0027406999
-
Striatal binding of the PET ligand 11C-raclopride is altered by drugs that modify synaptic dopamine levels
-
Dewey SL, Smith GS, Logan J, Brodie JD, Fowler JS, Wolf AP (1993) Striatal binding of the PET ligand 11C-raclopride is altered by drugs that modify synaptic dopamine levels. Synapse 13: 350-356
-
(1993)
Synapse
, vol.13
, pp. 350-356
-
-
Dewey, S.L.1
Smith, G.S.2
Logan, J.3
Brodie, J.D.4
Fowler, J.S.5
Wolf, A.P.6
-
24
-
-
0343933624
-
Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats
-
Di Chiara G, Imperato A (1988) Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. Proc Natl Acad Sci U S A 85: 5274-5278
-
(1988)
Proc Natl Acad Sci U S A
, vol.85
, pp. 5274-5278
-
-
Di Chiara, G.1
Imperato, A.2
-
25
-
-
85027910195
-
Brain activation induced by voluntary alcohol and saccharin drinking in rats assessed with manganese-enhanced magnetic resonance imaging
-
Dudek M, Abo-Ramadan U, Hermann D, Brown M, Canals S, Sommer WH, Hyytia P (2014) Brain activation induced by voluntary alcohol and saccharin drinking in rats assessed with manganese-enhanced magnetic resonance imaging. Addiction biology
-
(2014)
Addiction biology
-
-
Dudek, M.1
Abo-Ramadan, U.2
Hermann, D.3
Brown, M.4
Canals, S.5
Sommer, W.H.6
Hyytia, P.7
-
26
-
-
0017140489
-
Alcohol dependence: Provisional description of a clinical syndrome
-
Edwards G, Gross MM (1976) Alcohol dependence: provisional description of a clinical syndrome. Br Med J 1: 1058-1061
-
(1976)
Br Med J
, vol.1
, pp. 1058-1061
-
-
Edwards, G.1
Gross, M.M.2
-
27
-
-
28744441117
-
Can experimental paradigms and animal models be used to discover clinically effective medications for alcoholism?
-
Egli M (2005) Can experimental paradigms and animal models be used to discover clinically effective medications for alcoholism? Addict Biol 10: 309-319
-
(2005)
Addict Biol
, vol.10
, pp. 309-319
-
-
Egli, M.1
-
28
-
-
0030612619
-
Kinetic modeling of [11C]raclopride: Combined PET-microdialysis studies
-
Endres CJ, Kolachana BS, Saunders RC, Su T, Weinberger D, Breier A, Eckelman WC, Carson RE (1997) Kinetic modeling of [11C]raclopride: combined PET-microdialysis studies. J Cereb Blood Flow Metab 17: 932-942
-
(1997)
J Cereb Blood Flow Metab
, vol.17
, pp. 932-942
-
-
Endres, C.J.1
Kolachana, B.S.2
Saunders, R.C.3
Su, T.4
Weinberger, D.5
Breier, A.6
Eckelman, W.C.7
Carson, R.E.8
-
29
-
-
84884284352
-
Ethanol-induced alterations of amino acids measured by in vivo microdialysis in rats: A meta-analysis
-
Fliegel S, Brand I, Spanagel R, Noori HR (2013) Ethanol-induced alterations of amino acids measured by in vivo microdialysis in rats: a meta-analysis. Silico Pharmacology 1: 7
-
(2013)
Silico Pharmacology
, vol.1
, pp. 7
-
-
Fliegel, S.1
Brand, I.2
Spanagel, R.3
Noori, H.R.4
-
30
-
-
84903884663
-
-
Addiction
-
Garbutt JC, Greenblatt AM, West SL, Morgan LC, Kampov-Polevoy A, Jordan HS, Bobashev GV (2014) Clinical and biological moderators of response to naltrexone in alcohol dependence: a systematic review of the evidence. Addiction
-
(2014)
Clinical and biological moderators of response to naltrexone in alcohol dependence: A systematic review of the evidence
-
-
Garbutt, J.C.1
Greenblatt, A.M.2
West, S.L.3
Morgan, L.C.4
Kampov-Polevoy, A.5
Jordan, H.S.6
Bobashev, G.V.7
-
31
-
-
84901455026
-
Enhancement of extinction learning attenuates ethanol-seeking behavior and alters plasticity in the prefrontal cortex
-
Gass JT, Trantham-Davidson H, Kassab AS, Glen WB Jr, Olive MF, Chandler LJ (2014) Enhancement of extinction learning attenuates ethanol-seeking behavior and alters plasticity in the prefrontal cortex. J Neurosci 34: 7562-7574
-
(2014)
J Neurosci
, vol.34
, pp. 7562-7574
-
-
Gass, J.T.1
Trantham-Davidson, H.2
Kassab, A.S.3
Glen, W.B.4
Olive, M.F.5
Chandler, L.J.6
-
32
-
-
84856034355
-
Subjective and neural responses to intravenous alcohol in young adults with light and heavy drinking patterns
-
Gilman JM, Ramchandani VA, Crouss T, Hommer DW (2012) Subjective and neural responses to intravenous alcohol in young adults with light and heavy drinking patterns. Neuropsychopharmacology 37: 467-477
-
(2012)
Neuropsychopharmacology
, vol.37
, pp. 467-477
-
-
Gilman, J.M.1
Ramchandani, V.A.2
Crouss, T.3
Hommer, D.W.4
-
33
-
-
44649095315
-
Why we like to drink: A functional magnetic resonance imaging study of the rewarding and anxiolytic effects of alcohol
-
Gilman JM, Ramchandani VA, Davis MB, Bjork JM, Hommer DW (2008) Why we like to drink: a functional magnetic resonance imaging study of the rewarding and anxiolytic effects of alcohol. J Neurosci 28: 4583-4591
-
(2008)
J Neurosci
, vol.28
, pp. 4583-4591
-
-
Gilman, J.M.1
Ramchandani, V.A.2
Davis, M.B.3
Bjork, J.M.4
Hommer, D.W.5
-
35
-
-
0036330007
-
Toward wisdom from failure: Lessons from neuroprotective stroke trials and new therapeutic directions
-
Gladstone DJ, Black SE, Hakim AM, Heart, Stroke Foundation of Ontario Centre of Excellence in Stroke R (2002) Toward wisdom from failure: lessons from neuroprotective stroke trials and new therapeutic directions. Stroke 33: 2123-2136
-
(2002)
Stroke
, vol.33
, pp. 2123-2136
-
-
Gladstone, D.J.1
Black, S.E.2
Hakim, A.M.3
-
36
-
-
84871769521
-
Reward and relief craving tendencies in patients with alcohol use disorders: Results from the PREDICT study
-
Glockner-Rist A, Lemenager T, Mann K, Group PSR (2013) Reward and relief craving tendencies in patients with alcohol use disorders: results from the PREDICT study. Addict Behav 38: 1532-1540
-
(2013)
Addict Behav
, vol.38
, pp. 1532-1540
-
-
Glockner-Rist, A.1
Lemenager, T.2
Mann, K.3
Group, P.S.R.4
-
37
-
-
0032535299
-
Suppression of ethanol-reinforced behavior by naltrexone is associated with attenuation of the ethanol-induced increase in dialysate dopamine levels in the nucleus accumbens
-
Gonzales RA, Weiss F (1998) Suppression of ethanol-reinforced behavior by naltrexone is associated with attenuation of the ethanol-induced increase in dialysate dopamine levels in the nucleus accumbens. J Neurosci 18: 10663-10671
-
(1998)
J Neurosci
, vol.18
, pp. 10663-10671
-
-
Gonzales, R.A.1
Weiss, F.2
-
38
-
-
0038823525
-
The endophenotype concept in psychiatry: Etymology and strategic intentions
-
Gottesman II, Gould TD (2003) The endophenotype concept in psychiatry: etymology and strategic intentions. AJ Psychiatry 160: 636-645
-
(2003)
AJ Psychiatry
, vol.160
, pp. 636-645
-
-
Gottesman, I.I.1
Gould, T.D.2
-
39
-
-
3543055314
-
Prevalence and co-occurrence of substance use disorders and independent mood and anxiety disorders: Results from the national epidemiologic survey on alcohol and related conditions
-
Grant BF, Stinson FS, Dawson DA, Chou SP, Dufour MC, Compton W, Pickering RP, Kaplan K (2004) Prevalence and co-occurrence of substance use disorders and independent mood and anxiety disorders: results from the national epidemiologic survey on alcohol and related conditions. Arch Gen Psychiatry 61: 807-816
-
(2004)
Arch Gen Psychiatry
, vol.61
, pp. 807-816
-
-
Grant, B.F.1
Stinson, F.S.2
Dawson, D.A.3
Chou, S.P.4
Dufour, M.C.5
Compton, W.6
Pickering, R.P.7
Kaplan, K.8
-
40
-
-
33746325472
-
Pharmacological treatment of alcohol dependence: Target symptoms and target mechanisms
-
Heilig M, Egli M (2006) Pharmacological treatment of alcohol dependence: target symptoms and target mechanisms. Pharmacol Ther 111: 855-876
-
(2006)
Pharmacol Ther
, vol.111
, pp. 855-876
-
-
Heilig, M.1
Egli, M.2
-
41
-
-
76749117168
-
Acute withdrawal, protracted abstinence and negative affect in alcoholism: Are they linked?
-
Heilig M, Egli M, Crabbe JC, Becker HC (2010) Acute withdrawal, protracted abstinence and negative affect in alcoholism: are they linked? Addict Biol 15: 169-184
-
(2010)
Addict Biol
, vol.15
, pp. 169-184
-
-
Heilig, M.1
Egli, M.2
Crabbe, J.C.3
Becker, H.C.4
-
43
-
-
34447644753
-
A key role for corticotropin-releasing factor in alcohol dependence
-
Heilig M, Koob GF (2007) A key role for corticotropin-releasing factor in alcohol dependence. Trends Neurosci 30: 399-406
-
(2007)
Trends Neurosci
, vol.30
, pp. 399-406
-
-
Heilig, M.1
Koob, G.F.2
-
44
-
-
84861096333
-
Translational magnetic resonance spectroscopy reveals excessive central glutamate levels during alcohol withdrawal in humans and rats
-
Hermann D, Weber-Fahr W, Sartorius A, Hoerst M, Frischknecht U, Tunc-Skarka N, Perreau-Lenz S, Hansson AC, Krumm B, Kiefer F, Spanagel R, Mann K, Ende G, Sommer WH (2012) Translational magnetic resonance spectroscopy reveals excessive central glutamate levels during alcohol withdrawal in humans and rats. Biol Psychiatry 71: 1015-1021
-
(2012)
Biol Psychiatry
, vol.71
, pp. 1015-1021
-
-
Hermann, D.1
Weber-Fahr, W.2
Sartorius, A.3
Hoerst, M.4
Frischknecht, U.5
Tunc-Skarka, N.6
Perreau-Lenz, S.7
Hansson, A.C.8
Krumm, B.9
Kiefer, F.10
Spanagel, R.11
Mann, K.12
Ende, G.13
Sommer, W.H.14
-
47
-
-
84879957118
-
Into the valley of death: Research to innovation
-
Hudson J, Khazragui HF (2013) Into the valley of death: research to innovation. Drug Discovery Today 18: 610-613
-
(2013)
Drug Discovery Today
, vol.18
, pp. 610-613
-
-
Hudson, J.1
Khazragui, H.F.2
-
48
-
-
1542316822
-
Measurement of brain glutamate using TE-averaged PRESS at 3T
-
Hurd R, Sailasuta N, Srinivasan R, Vigneron DB, Pelletier D, Nelson SJ (2004) Measurement of brain glutamate using TE-averaged PRESS at 3T. Magn Reson Med 51: 435-440
-
(2004)
Magn Reson Med
, vol.51
, pp. 435-440
-
-
Hurd, R.1
Sailasuta, N.2
Srinivasan, R.3
Vigneron, D.B.4
Pelletier, D.5
Nelson, S.J.6
-
49
-
-
84867439307
-
Revolution stalled
-
Hyman SE (2012) Revolution stalled. Sci Trans Med 4: 155cm111
-
(2012)
Sci Trans Med
, vol.4
, pp. 155cm111
-
-
Hyman, S.E.1
-
50
-
-
70350741238
-
Endophenotypes: Bridging genomic complexity and disorder heterogeneity
-
Insel TR, Cuthbert BN (2009) Endophenotypes: bridging genomic complexity and disorder heterogeneity. Biol Psychiatry 66: 988-989
-
(2009)
Biol Psychiatry
, vol.66
, pp. 988-989
-
-
Insel, T.R.1
Cuthbert, B.N.2
-
51
-
-
33748362868
-
Ghrelin stimulates locomotor activity and accumbal dopamine-overflow via central cholinergic systems in mice: Implications for its involvement in brain reward
-
Jerlhag E, Egecioglu E, Dickson SL, Andersson M, Svensson L, Engel JA (2006) Ghrelin stimulates locomotor activity and accumbal dopamine-overflow via central cholinergic systems in mice: implications for its involvement in brain reward. Addict Biol 11: 45-54
-
(2006)
Addict Biol
, vol.11
, pp. 45-54
-
-
Jerlhag, E.1
Egecioglu, E.2
Dickson, S.L.3
Andersson, M.4
Svensson, L.5
Engel, J.A.6
-
52
-
-
67650500621
-
Requirement of central ghrelin signaling for alcohol reward
-
Jerlhag E, Egecioglu E, Landgren S, Salome N, Heilig M, Moechars D, Datta R, Perrissoud D, Dickson SL, Engel JA (2009) Requirement of central ghrelin signaling for alcohol reward. Proc Natl Acad Sci U S A 106: 11318-11323
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 11318-11323
-
-
Jerlhag, E.1
Egecioglu, E.2
Landgren, S.3
Salome, N.4
Heilig, M.5
Moechars, D.6
Datta, R.7
Perrissoud, D.8
Dickson, S.L.9
Engel, J.A.10
-
53
-
-
84871976642
-
Excess mortality of alcohol-dependent individuals after 14 years and mortality predictors based on treatment participation and severity of alcohol dependence
-
John U, Rumpf HJ, Bischof G, Hapke U, Hanke M, Meyer C (2013) Excess mortality of alcohol-dependent individuals after 14 years and mortality predictors based on treatment participation and severity of alcohol dependence. Alcohol Clin Exp Res 37: 156-163
-
(2013)
Alcohol Clin Exp Res
, vol.37
, pp. 156-163
-
-
John, U.1
Rumpf, H.J.2
Bischof, G.3
Hapke, U.4
Hanke, M.5
Meyer, C.6
-
54
-
-
84900333411
-
Pharmacotherapy for adults with alcohol use disorders in outpatient settings a systematic review and meta-analysis
-
Jonas DE, Amick HR, Feltner C, Bobashev G, Thomas K, Wines R, Kim MM, Shanahan E, Gass CE, Rowe CJ, Garbutt JC (2014) Pharmacotherapy for adults with alcohol use disorders in outpatient settings a systematic review and meta-analysis. Jama-J Am Med Assoc 311: 1889-1900
-
(2014)
Jama-J Am Med Assoc
, vol.311
, pp. 1889-1900
-
-
Jonas, D.E.1
Amick, H.R.2
Feltner, C.3
Bobashev, G.4
Thomas, K.5
Wines, R.6
Kim, M.M.7
Shanahan, E.8
Gass, C.E.9
Rowe, C.J.10
Garbutt, J.C.11
-
55
-
-
84884291631
-
Effect of modafinil on impulsivity and relapse in alcohol dependent patients: A randomized, placebo-controlled trial
-
Joos L, Goudriaan AE, Schmaal L, Fransen E, van den Brink W, Sabbe BG, Dom G (2013) Effect of modafinil on impulsivity and relapse in alcohol dependent patients: a randomized, placebo-controlled trial. Eur Neuropsychopharmacol 23: 948-955
-
(2013)
Eur Neuropsychopharmacol
, vol.23
, pp. 948-955
-
-
Joos, L.1
Goudriaan, A.E.2
Schmaal, L.3
Fransen, E.4
van den Brink, W.5
Sabbe, B.G.6
Dom, G.7
-
56
-
-
79955486643
-
Exploratory analyses of efficacy data from major depressive disorder trials submitted to the US food and drug administration in support of new drug applications
-
Khin NA, Chen YF, Yang Y, Yang P, Laughren TP (2011) Exploratory analyses of efficacy data from major depressive disorder trials submitted to the US food and drug administration in support of new drug applications. J Clin Psychiatry 72: 464-472
-
(2011)
J Clin Psychiatry
, vol.72
, pp. 464-472
-
-
Khin, N.A.1
Chen, Y.F.2
Yang, Y.3
Yang, P.4
Laughren, T.P.5
-
57
-
-
33847651376
-
Linking nucleus accumbens dopamine and blood oxygenation
-
Knutson B, Gibbs SE (2007) Linking nucleus accumbens dopamine and blood oxygenation. Psychopharmacology 191: 813-822
-
(2007)
Psychopharmacology
, vol.191
, pp. 813-822
-
-
Knutson, B.1
Gibbs, S.E.2
-
58
-
-
41549113416
-
Addiction and the brain antireward system
-
Koob GF, Le Moal M (2008) Addiction and the brain antireward system. Annu Rev Psychol 59: 29-53
-
(2008)
Annu Rev Psychol
, vol.59
, pp. 29-53
-
-
Koob, G.F.1
Le Moal, M.2
-
59
-
-
84925514304
-
The corticotropin releasing hormone-1 (CRH1) receptor antagonist pexacerfont in alcohol dependence: A randomized controlled experimental medicine study
-
Kwako LE, Spagnolo PA, Schwandt ML, Thorsell A, George DT, Momenan R, Rio DE, Huestis M, Anizan S, Concheiro M, Sinha R, Heilig M (2014) The corticotropin releasing hormone-1 (CRH1) receptor antagonist pexacerfont in alcohol dependence: a randomized controlled experimental medicine study. Neuropsychopharmacology
-
(2014)
Neuropsychopharmacology
-
-
Kwako, L.E.1
Spagnolo, P.A.2
Schwandt, M.L.3
Thorsell, A.4
George, D.T.5
Momenan, R.6
Rio, D.E.7
Huestis, M.8
Anizan, S.9
Concheiro, M.10
Sinha, R.11
Heilig, M.12
-
60
-
-
84255177243
-
Ghrelin receptor (GHS-R1A) antagonism suppresses both operant alcohol self-administration and high alcohol consumption in rats
-
Landgren S, Simms JA, Hyytia P, Engel JA, Bartlett SE, Jerlhag E (2012) Ghrelin receptor (GHS-R1A) antagonism suppresses both operant alcohol self-administration and high alcohol consumption in rats. Addict Biol 17: 86-94
-
(2012)
Addict Biol
, vol.17
, pp. 86-94
-
-
Landgren, S.1
Simms, J.A.2
Hyytia, P.3
Engel, J.A.4
Bartlett, S.E.5
Jerlhag, E.6
-
61
-
-
84860229812
-
Medications development to treat alcohol dependence: A vision for the next decade
-
Litten RZ, Egli M, Heilig M, Cui C, Fertig JB, Ryan ML, Falk DE, Moss H, Huebner R, Noronha A (2012) Medications development to treat alcohol dependence: a vision for the next decade. Addict Biol 17: 513-527
-
(2012)
Addict Biol
, vol.17
, pp. 513-527
-
-
Litten, R.Z.1
Egli, M.2
Heilig, M.3
Cui, C.4
Fertig, J.B.5
Ryan, M.L.6
Falk, D.E.7
Moss, H.8
Huebner, R.9
Noronha, A.10
-
62
-
-
84875713675
-
Extending the treatment options in alcohol dependence: A randomized controlled study of as-needed nalmefene
-
Mann K, Bladstrom A, Torup L, Gual A, van den Brink W (2013) Extending the treatment options in alcohol dependence: a randomized controlled study of as-needed nalmefene. Biol Psychiatry 73: 706-713
-
(2013)
Biol Psychiatry
, vol.73
, pp. 706-713
-
-
Mann, K.1
Bladstrom, A.2
Torup, L.3
Gual, A.4
van den Brink, W.5
-
63
-
-
57049118462
-
Alcohol and opioid dependence medications: Prescription trends, overall and by physician specialty
-
Mark TL, Kassed CA, Vandivort-Warren R, Levit KR, Kranzler HR (2009) Alcohol and opioid dependence medications: prescription trends, overall and by physician specialty. Drug Alcohol Depend 99: 345-349
-
(2009)
Drug Alcohol Depend
, vol.99
, pp. 345-349
-
-
Mark, T.L.1
Kassed, C.A.2
Vandivort-Warren, R.3
Levit, K.R.4
Kranzler, H.R.5
-
64
-
-
1542264857
-
Understanding US addiction physicians’ low rate of naltrexone prescription
-
Mark TL, Kranzler HR, Song X (2003) Understanding US addiction physicians’ low rate of naltrexone prescription. Drug Alcohol Depend 71: 219-228
-
(2003)
Drug Alcohol Depend
, vol.71
, pp. 219-228
-
-
Mark, T.L.1
Kranzler, H.R.2
Song, X.3
-
65
-
-
27944446443
-
Alcohol dependence is associated with blunted dopamine transmission in the ventral striatum
-
Martinez D, Gil R, Slifstein M, Hwang DR, Huang Y, Perez A, Kegeles L, Talbot P, Evans S, Krystal J, Laruelle M, Abi-Dargham A (2005) Alcohol dependence is associated with blunted dopamine transmission in the ventral striatum. Biol Psychiatry 58: 779-786
-
(2005)
Biol Psychiatry
, vol.58
, pp. 779-786
-
-
Martinez, D.1
Gil, R.2
Slifstein, M.3
Hwang, D.R.4
Huang, Y.5
Perez, A.6
Kegeles, L.7
Talbot, P.8
Evans, S.9
Krystal, J.10
Laruelle, M.11
Abi-Dargham, A.12
-
66
-
-
84873691604
-
Rescue of infralimbic mGluR2 deficit restores control over drug-seeking behavior in alcohol dependence
-
Meinhardt MW, Hansson AC, Perreau-Lenz S, Bauder-Wenz C, Stahlin O, Heilig M, Harper C, Drescher KU, Spanagel R, Sommer WH (2013) Rescue of infralimbic mGluR2 deficit restores control over drug-seeking behavior in alcohol dependence. J Neurosci 33: 2794-2806
-
(2013)
J Neurosci
, vol.33
, pp. 2794-2806
-
-
Meinhardt, M.W.1
Hansson, A.C.2
Perreau-Lenz, S.3
Bauder-Wenz, C.4
Stahlin, O.5
Heilig, M.6
Harper, C.7
Drescher, K.U.8
Spanagel, R.9
Sommer, W.H.10
-
67
-
-
84919846348
-
Postdependent state in rats as a model for medication development in alcoholism
-
Meinhardt MW, Sommer WH (2015) Postdependent state in rats as a model for medication development in alcoholism. Addict Biol 20: 1-21
-
(2015)
Addict Biol
, vol.20
, pp. 1-21
-
-
Meinhardt, M.W.1
Sommer, W.H.2
-
68
-
-
77955114844
-
Is pharma running out of brainy ideas?
-
Miller G (2010) Is pharma running out of brainy ideas? Science 329: 502-504
-
(2010)
Science
, vol.329
, pp. 502-504
-
-
Miller, G.1
-
69
-
-
84857051538
-
Brain-specific inactivation of the Crhr1 gene inhibits post-dependent and stress-induced alcohol intake, but does not affect relapse-like drinking
-
Molander A, Vengeliene V, Heilig M, Wurst W, Deussing JM, Spanagel R (2012) Brain-specific inactivation of the Crhr1 gene inhibits post-dependent and stress-induced alcohol intake, but does not affect relapse-like drinking. Neuropsychopharmacology 37: 1047-1056
-
(2012)
Neuropsychopharmacology
, vol.37
, pp. 1047-1056
-
-
Molander, A.1
Vengeliene, V.2
Heilig, M.3
Wurst, W.4
Deussing, J.M.5
Spanagel, R.6
-
71
-
-
41449100841
-
Serotonin transporter (5-HTTLPR) genotype and amygdala activation: A meta-analysis
-
Munafo MR, Brown SM, Hariri AR (2008) Serotonin transporter (5-HTTLPR) genotype and amygdala activation: a meta-analysis. Biol Psychiatry 63: 852-857
-
(2008)
Biol Psychiatry
, vol.63
, pp. 852-857
-
-
Munafo, M.R.1
Brown, S.M.2
Hariri, A.R.3
-
72
-
-
78149362118
-
Drug harms in the UK: A multicriteria decision analysis
-
Nutt DJ, King LA, Phillips LD, Independent Scientific Committee on D (2010) Drug harms in the UK: a multicriteria decision analysis. Lancet 376: 1558-1565
-
(2010)
Lancet
, vol.376
, pp. 1558-1565
-
-
Nutt, D.J.1
King, L.A.2
Phillips, L.D.3
-
73
-
-
0026498986
-
Naltrexone and coping skills therapy for alcohol dependence. A controlled study
-
O’Malley SS, Jaffe AJ, Chang G, Schottenfeld RS, Meyer RE, Rounsaville B (1992) Naltrexone and coping skills therapy for alcohol dependence. A controlled study. Arch Gen Psychiatry 49: 881-887
-
(1992)
Arch Gen Psychiatry
, vol.49
, pp. 881-887
-
-
O’Malley, S.S.1
Jaffe, A.J.2
Chang, G.3
Schottenfeld, R.S.4
Meyer, R.E.5
Rounsaville, B.6
-
74
-
-
0041383898
-
A functional polymorphism of the mu-opioid receptor gene is associated with naltrexone response in alcohol-dependent patients
-
Oslin DW, Berrettini W, Kranzler HR, Pettinati H, Gelernter J, Volpicelli JR, O’Brien CP (2003) A functional polymorphism of the mu-opioid receptor gene is associated with naltrexone response in alcohol-dependent patients. Neuropsychopharmacology 28: 1546-1552
-
(2003)
Neuropsychopharmacology
, vol.28
, pp. 1546-1552
-
-
Oslin, D.W.1
Berrettini, W.2
Kranzler, H.R.3
Pettinati, H.4
Gelernter, J.5
Volpicelli, J.R.6
O’Brien, C.P.7
-
75
-
-
84884289422
-
A multistep general theory of transition to addiction
-
Piazza PV, Deroche-Gamonet V (2013) A multistep general theory of transition to addiction. Psychopharmacology 229: 387-413
-
(2013)
Psychopharmacology
, vol.229
, pp. 387-413
-
-
Piazza, P.V.1
Deroche-Gamonet, V.2
-
76
-
-
79960846324
-
A genetic determinant of the striatal dopamine response to alcohol in men
-
Ramchandani VA, Umhau J, Pavon FJ, Ruiz-Velasco V, Margas W, Sun H, Damadzic R, Eskay R, Schoor M, Thorsell A, Schwandt ML, Sommer WH, George DT, Parsons LH, Herscovitch P, Hommer D, Heilig M (2011) A genetic determinant of the striatal dopamine response to alcohol in men. Mol Psychiatry 16: 809-817
-
(2011)
Mol Psychiatry
, vol.16
, pp. 809-817
-
-
Ramchandani, V.A.1
Umhau, J.2
Pavon, F.J.3
Ruiz-Velasco, V.4
Margas, W.5
Sun, H.6
Damadzic, R.7
Eskay, R.8
Schoor, M.9
Thorsell, A.10
Schwandt, M.L.11
Sommer, W.H.12
George, D.T.13
Parsons, L.H.14
Herscovitch, P.15
Hommer, D.16
Heilig, M.17
-
77
-
-
80053365601
-
Glutamatergic and dopaminergic neurons mediate anxiogenic and anxiolytic effects of CRHR1
-
Refojo D, Schweizer M, Kuehne C, Ehrenberg S, Thoeringer C, Vogl AM, Dedic N, Schumacher M, von Wolff G, Avrabos C, Touma C, Engblom D, Schutz G, Nave KA, Eder M, Wotjak CT, Sillaber I, Holsboer F, Wurst W, Deussing JM (2011) Glutamatergic and dopaminergic neurons mediate anxiogenic and anxiolytic effects of CRHR1. Science 333: 1903-1907
-
(2011)
Science
, vol.333
, pp. 1903-1907
-
-
Refojo, D.1
Schweizer, M.2
Kuehne, C.3
Ehrenberg, S.4
Thoeringer, C.5
Vogl, A.M.6
Dedic, N.7
Schumacher, M.8
von Wolff, G.9
Avrabos, C.10
Touma, C.11
Engblom, D.12
Schutz, G.13
Nave, K.A.14
Eder, M.15
Wotjak, C.T.16
Sillaber, I.17
Holsboer, F.18
Wurst, W.19
Deussing, J.M.20
more..
-
78
-
-
0042835508
-
The relationship of average volume of alcohol consumption and patterns of drinking to burden of disease: An overview
-
Rehm J, Room R, Graham K, Monteiro M, Gmel G, Sempos CT (2003) The relationship of average volume of alcohol consumption and patterns of drinking to burden of disease: an overview. Addiction 98: 1209-1228
-
(2003)
Addiction
, vol.98
, pp. 1209-1228
-
-
Rehm, J.1
Room, R.2
Graham, K.3
Monteiro, M.4
Gmel, G.5
Sempos, C.T.6
-
79
-
-
0029119866
-
Ethanol withdrawal is associated with increased extracellular glutamate in the rat striatum
-
Rossetti ZL, Carboni S (1995) Ethanol withdrawal is associated with increased extracellular glutamate in the rat striatum. Eur J Pharmacol 283: 177-183
-
(1995)
Eur J Pharmacol
, vol.283
, pp. 177-183
-
-
Rossetti, Z.L.1
Carboni, S.2
-
80
-
-
84904804929
-
Biological insights from 108 schizophrenia-associated genetic loci
-
Schizophrenia Working Group of the Psychiatric Genomics C (2014) Biological insights from 108 schizophrenia-associated genetic loci. Nature 511: 421-427
-
(2014)
Nature
, vol.511
, pp. 421-427
-
-
-
81
-
-
84875736241
-
Modafinil modulates resting-state functional network connectivity and cognitive control in alcohol-dependent patients
-
Schmaal L, Goudriaan AE, Joos L, Kruse AM, Dom G, van den Brink W, Veltman DJ (2013) Modafinil modulates resting-state functional network connectivity and cognitive control in alcohol-dependent patients. Biol Psychiatry 73: 789-795
-
(2013)
Biol Psychiatry
, vol.73
, pp. 789-795
-
-
Schmaal, L.1
Goudriaan, A.E.2
Joos, L.3
Kruse, A.M.4
Dom, G.5
van den Brink, W.6
Veltman, D.J.7
-
82
-
-
84855342146
-
Within-subject comparison of [(11)C]-(+)-PHNO and [(11)C]raclopride sensitivity to acute amphetamine challenge in healthy humans
-
Shotbolt P, Tziortzi AC, Searle GE, Colasanti A, van der Aart J, Abanades S, Plisson C, Miller SR, Huiban M, Beaver JD, Gunn RN, Laruelle M, Rabiner EA (2012) Within-subject comparison of [(11)C]-(+)-PHNO and [(11)C]raclopride sensitivity to acute amphetamine challenge in healthy humans. J Cereb Blood Flow Metab 32: 127-136
-
(2012)
J Cereb Blood Flow Metab
, vol.32
, pp. 127-136
-
-
Shotbolt, P.1
Tziortzi, A.C.2
Searle, G.E.3
Colasanti, A.4
van der Aart, J.5
Abanades, S.6
Plisson, C.7
Miller, S.R.8
Huiban, M.9
Beaver, J.D.10
Gunn, R.N.11
Laruelle, M.12
Rabiner, E.A.13
-
83
-
-
0037012953
-
Enhanced and delayed stress-induced alcohol drinking in mice lacking functional CRH1 receptors
-
Sillaber I, Rammes G, Zimmermann S, Mahal B, Zieglgansberger W, Wurst W, Holsboer F, Spanagel R (2002) Enhanced and delayed stress-induced alcohol drinking in mice lacking functional CRH1 receptors. Science 296: 931-933
-
(2002)
Science
, vol.296
, pp. 931-933
-
-
Sillaber, I.1
Rammes, G.2
Zimmermann, S.3
Mahal, B.4
Zieglgansberger, W.5
Wurst, W.6
Holsboer, F.7
Spanagel, R.8
-
84
-
-
84924974388
-
Effects of naltrexone on neural and subjective response to alcohol in treatment-seeking alcohol-dependent patients
-
Spagnolo PA, Ramchandani VA, Schwandt ML, Zhang L, Blaine SK, Usala JM, Diamond KA, Phillips MJ, George DT, Momenan R, Heilig M (2014) Effects of naltrexone on neural and subjective response to alcohol in treatment-seeking alcohol-dependent patients. Alcohol Clin Exp Res 38: 3024-3032
-
(2014)
Alcohol Clin Exp Res
, vol.38
, pp. 3024-3032
-
-
Spagnolo, P.A.1
Ramchandani, V.A.2
Schwandt, M.L.3
Zhang, L.4
Blaine, S.K.5
Usala, J.M.6
Diamond, K.A.7
Phillips, M.J.8
George, D.T.9
Momenan, R.10
Heilig, M.11
-
85
-
-
67649985942
-
Alcoholism: A systems approach from molecular physiology to addictive behavior
-
Spanagel R (2009) Alcoholism: a systems approach from molecular physiology to addictive behavior. Physiol Rev 89: 649-705
-
(2009)
Physiol Rev
, vol.89
, pp. 649-705
-
-
Spanagel, R.1
-
86
-
-
77950350658
-
Are metabotropic glutamate receptors promising targets for the treatment of alcoholism?
-
Spanagel R (2010) Are metabotropic glutamate receptors promising targets for the treatment of alcoholism? Biol Psychiatry 67: 798-799
-
(2010)
Biol Psychiatry
, vol.67
, pp. 798-799
-
-
Spanagel, R.1
-
87
-
-
39749088094
-
Drugs for relapse prevention of alcoholism: Ten years of progress
-
Spanagel R, Kiefer F (2008) Drugs for relapse prevention of alcoholism: ten years of progress. Trends Pharmacol Sci 29: 109-115
-
(2008)
Trends Pharmacol Sci
, vol.29
, pp. 109-115
-
-
Spanagel, R.1
Kiefer, F.2
-
88
-
-
13444254068
-
The clock gene Per2 influences the glutamatergic system and modulates alcohol consumption
-
Spanagel R, Pendyala G, Abarca C, Zghoul T, Sanchis-Segura C, Magnone MC, Lascorz J, Depner M, Holzberg D, Soyka M, Schreiber S, Matsuda F, Lathrop M, Schumann G, Albrecht U (2005) The clock gene Per2 influences the glutamatergic system and modulates alcohol consumption. Nat Med 11: 35-42
-
(2005)
Nat Med
, vol.11
, pp. 35-42
-
-
Spanagel, R.1
Pendyala, G.2
Abarca, C.3
Zghoul, T.4
Sanchis-Segura, C.5
Magnone, M.C.6
Lascorz, J.7
Depner, M.8
Holzberg, D.9
Soyka, M.10
Schreiber, S.11
Matsuda, F.12
Lathrop, M.13
Schumann, G.14
Albrecht, U.15
-
89
-
-
84894084878
-
Acamprosate produces its anti-relapse effects via calcium
-
Spanagel R, Vengeliene V, Jandeleit B, Fischer WN, Grindstaff K, Zhang X, Gallop MA, Krstew EV, Lawrence AJ, Kiefer F (2014) Acamprosate produces its anti-relapse effects via calcium. Neuropsychopharmacology 39: 783-791
-
(2014)
Neuropsychopharmacology
, vol.39
, pp. 783-791
-
-
Spanagel, R.1
Vengeliene, V.2
Jandeleit, B.3
Fischer, W.N.4
Grindstaff, K.5
Zhang, X.6
Gallop, M.A.7
Krstew, E.V.8
Lawrence, A.J.9
Kiefer, F.10
-
90
-
-
33646126493
-
TE-averaged two-dimensional proton spectroscopic imaging of glutamate at 3 T
-
Srinivasan R, Cunningham C, Chen A, Vigneron D, Hurd R, Nelson S, Pelletier D (2006) TE-averaged two-dimensional proton spectroscopic imaging of glutamate at 3 T. Neuroimage 30: 1171-1178
-
(2006)
Neuroimage
, vol.30
, pp. 1171-1178
-
-
Srinivasan, R.1
Cunningham, C.2
Chen, A.3
Vigneron, D.4
Hurd, R.5
Nelson, S.6
Pelletier, D.7
-
91
-
-
0031595872
-
A dopamine-mu1 opioid link in the rat ventral tegmentum shared by palatable food (Fonzies) and non-psychostimulant drugs of abuse
-
Tanda G, Di Chiara G (1998) A dopamine-mu1 opioid link in the rat ventral tegmentum shared by palatable food (Fonzies) and non-psychostimulant drugs of abuse. Eur J Neurosci 10: 1179-1187
-
(1998)
Eur J Neurosci
, vol.10
, pp. 1179-1187
-
-
Tanda, G.1
Di Chiara, G.2
-
92
-
-
84895489827
-
Chronic alcohol disrupts dopamine receptor activity and the cognitive function of the medial prefrontal cortex
-
Trantham-Davidson H, Burnett EJ, Gass JT, Lopez MF, Mulholland PJ, Centanni SW, Floresco SB, Chandler LJ (2014) Chronic alcohol disrupts dopamine receptor activity and the cognitive function of the medial prefrontal cortex. J Neurosci 34: 3706-3718
-
(2014)
J Neurosci
, vol.34
, pp. 3706-3718
-
-
Trantham-Davidson, H.1
Burnett, E.J.2
Gass, J.T.3
Lopez, M.F.4
Mulholland, P.J.5
Centanni, S.W.6
Floresco, S.B.7
Chandler, L.J.8
-
93
-
-
77957690685
-
Effect of acamprosate on magnetic resonance spectroscopy measures of central glutamate in detoxified alcohol-dependent individuals: A randomized controlled experimental medicine study
-
Umhau JC, Momenan R, Schwandt ML, Singley E, Lifshitz M, Doty L, Adams LJ, Vengeliene V, Spanagel R, Zhang Y, Shen J, George DT, Hommer D, Heilig M (2010) Effect of acamprosate on magnetic resonance spectroscopy measures of central glutamate in detoxified alcohol-dependent individuals: a randomized controlled experimental medicine study. Arch Gen Psychiatry 67: 1069-1077
-
(2010)
Arch Gen Psychiatry
, vol.67
, pp. 1069-1077
-
-
Umhau, J.C.1
Momenan, R.2
Schwandt, M.L.3
Singley, E.4
Lifshitz, M.5
Doty, L.6
Adams, L.J.7
Vengeliene, V.8
Spanagel, R.9
Zhang, Y.10
Shen, J.11
George, D.T.12
Hommer, D.13
Heilig, M.14
-
94
-
-
77957366845
-
Sex differences in striatal dopamine release in young adults after oral alcohol challenge: A positron emission tomography imaging study with [(11)C] raclopride
-
Urban NB, Kegeles LS, Slifstein M, Xu X, Martinez D, Sakr E, Castillo F, Moadel T, O’Malley SS, Krystal JH, Abi-Dargham A (2010) Sex differences in striatal dopamine release in young adults after oral alcohol challenge: a positron emission tomography imaging study with [(11)C] raclopride. Biol Psychiatry 68: 689-696
-
(2010)
Biol Psychiatry
, vol.68
, pp. 689-696
-
-
Urban, N.B.1
Kegeles, L.S.2
Slifstein, M.3
Xu, X.4
Martinez, D.5
Sakr, E.6
Castillo, F.7
Moadel, T.8
O’Malley, S.S.9
Krystal, J.H.10
Abi-Dargham, A.11
-
95
-
-
3042779902
-
Dopamine in drug abuse and addiction: Results from imaging studies and treatment implications
-
Volkow ND, Fowler JS, Wang GJ, Swanson JM (2004) Dopamine in drug abuse and addiction: results from imaging studies and treatment implications. Mol Psychiatry 9: 557-569
-
(2004)
Mol Psychiatry
, vol.9
, pp. 557-569
-
-
Volkow, N.D.1
Fowler, J.S.2
Wang, G.J.3
Swanson, J.M.4
-
97
-
-
0027482405
-
Oral alcohol self-administration stimulates dopamine release in the rat nucleus accumbens: Genetic and motivational determinants
-
Weiss F, Lorang MT, Bloom FE, Koob GF (1993) Oral alcohol self-administration stimulates dopamine release in the rat nucleus accumbens: genetic and motivational determinants. J Pharmacol Exp Ther 267: 250-258
-
(1993)
J Pharmacol Exp Ther
, vol.267
, pp. 250-258
-
-
Weiss, F.1
Lorang, M.T.2
Bloom, F.E.3
Koob, G.F.4
-
98
-
-
84930202170
-
Mortality and life expectancy of people with alcohol use disorder in Denmark, Finland and Sweden
-
Westman J, Wahlbeck K, Laursen TM, Gissler M, Nordentoft M, Hallgren J, Arffman M, Osby U (2014) Mortality and life expectancy of people with alcohol use disorder in Denmark, Finland and Sweden. Acta Psychiatr Scand
-
(2014)
Acta Psychiatr Scand
-
-
Westman, J.1
Wahlbeck, K.2
Laursen, T.M.3
Gissler, M.4
Nordentoft, M.5
Hallgren, J.6
Arffman, M.7
Osby, U.8
-
99
-
-
84887259083
-
Global burden of disease attributable to mental and substance use disorders: Findings from the Global Burden of Disease Study 2010
-
Whiteford HA, Degenhardt L, Rehm J, Baxter AJ, Ferrari AJ, Erskine HE, Charlson FJ, Norman RE, Flaxman AD, Johns N, Burstein R, Murray CJ, Vos T (2013) Global burden of disease attributable to mental and substance use disorders: findings from the Global Burden of Disease Study 2010. Lancet 382: 1575-1586
-
(2013)
Lancet
, vol.382
, pp. 1575-1586
-
-
Whiteford, H.A.1
Degenhardt, L.2
Rehm, J.3
Baxter, A.J.4
Ferrari, A.J.5
Erskine, H.E.6
Charlson, F.J.7
Norman, R.E.8
Flaxman, A.D.9
Johns, N.10
Burstein, R.11
Murray, C.J.12
Vos, T.13
-
100
-
-
36949036673
-
First human evidence of d-amphetamine induced displacement of a D2/3 agonist radioligand: A [11C]-(+)-PHNO positron emission tomography study
-
Willeit M, Ginovart N, Graff A, Rusjan P, Vitcu I, Houle S, Seeman P, Wilson AA, Kapur S (2008) First human evidence of d-amphetamine induced displacement of a D2/3 agonist radioligand: A [11C]-(+)-PHNO positron emission tomography study. Neuropsychopharmacology 33: 279-289
-
(2008)
Neuropsychopharmacology
, vol.33
, pp. 279-289
-
-
Willeit, M.1
Ginovart, N.2
Graff, A.3
Rusjan, P.4
Vitcu, I.5
Houle, S.6
Seeman, P.7
Wilson, A.A.8
Kapur, S.9
-
101
-
-
0023426876
-
A psychomotor stimulant theory of addiction
-
Wise RA, Bozarth MA (1987) A psychomotor stimulant theory of addiction. Psychol Rev 94: 469-492
-
(1987)
Psychol Rev
, vol.94
, pp. 469-492
-
-
Wise, R.A.1
Bozarth, M.A.2
-
102
-
-
84885693012
-
Loss of metabotropic glutamate receptor 2 escalates alcohol consumption
-
Zhou Z, Karlsson C, Liang T, Xiong W, Kimura M, Tapocik JD, Yuan Q, Barbier E, Feng A, Flanigan M, Augier E, Enoch MA, Hodgkinson CA, Shen PH, Lovinger DM, Edenberg HJ, Heilig M, Goldman D (2013) Loss of metabotropic glutamate receptor 2 escalates alcohol consumption. Proc Natl Acad Sci U S A 110: 16963-16968
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 16963-16968
-
-
Zhou, Z.1
Karlsson, C.2
Liang, T.3
Xiong, W.4
Kimura, M.5
Tapocik, J.D.6
Yuan, Q.7
Barbier, E.8
Feng, A.9
Flanigan, M.10
Augier, E.11
Enoch, M.A.12
Hodgkinson, C.A.13
Shen, P.H.14
Lovinger, D.M.15
Edenberg, H.J.16
Heilig, M.17
Goldman, D.18
-
103
-
-
84880982689
-
Behavioral, biological, and chemical perspectives on targeting CRF(1) receptor antagonists to treat alcoholism
-
Zorrilla EP, Heilig M, de Wit H, Shaham Y (2013) Behavioral, biological, and chemical perspectives on targeting CRF(1) receptor antagonists to treat alcoholism. Drug Alcohol Depend 128: 175-186
-
(2013)
Drug Alcohol Depend
, vol.128
, pp. 175-186
-
-
Zorrilla, E.P.1
Heilig, M.2
de Wit, H.3
Shaham, Y.4
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