Alcohol promotes dopamine release in the human nucleus accumbens

Synapse

Volumn 49, Issue 4, 2003, Pages 226-231

  Boileau, Isabelle ^a   Assaad, Jean Marc ^b,c   Pihl, Robert O ^b   Benkelfat, Chawki ^b   Leyton, Marco ^b   Diksic, Mirko ^a   Tremblay, Richard E ^c   Dagher, Alain ^a,d  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

^d MCGILL UNIVERSITY   (Canada)

Author keywords

11C raclopride; Addiction; CNS stimulants; Heart rate; Impulsivity; Personality; PET

Indexed keywords

ALCOHOL; DOPAMINE; RACLOPRIDE; RACLOPRIDE C 11; UNCLASSIFIED DRUG;

ADULT; ALCOHOL BLOOD LEVEL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINE RELEASE; DRUG ABUSE; HEART RATE; HUMAN; HUMAN EXPERIMENT; IMPULSIVENESS; LIMBIC CORTEX; MALE; MICRODIALYSIS; MOOD DISORDER; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEUS ACCUMBENS; PARAMETRIC TEST; PERSONALITY; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; QUESTIONNAIRE; REINFORCEMENT; RODENT; STATISTICAL PARAMETRIC MAP; TRIDIMENSIONAL PERSONALITY QUESTIONNAIRE;

ADULT; ALCOHOL DRINKING; BASAL GANGLIA; CENTRAL NERVOUS SYSTEM DEPRESSANTS; DOPAMINE; DOPAMINE ANTAGONISTS; ETHANOL; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; NUCLEUS ACCUMBENS; RACLOPRIDE; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0041592759     PISSN: 08874476     EISSN: None     Source Type: Journal    
DOI: 10.1002/syn.10226     Document Type: Article

References (58)

1. Acquas E, Meloni M, Di Chiara G. 1993. Blockade of delta-opioid receptors in the nucleus accumbens prevents ethanol-induced stimulation of dopamine release. Eur J Pharmacol 230:239-241.
2. Aston JA, Gunn RN, Worsley KJ, Ma Y, Evans AC, Dagher A. 2000. A statistical method for the analysis of positron emission tomography neuroreceptor ligand data. Neuroimage 12:245-256.
3. Benjamin D, Grant ER, Pohorecky LA. 1993. Naltrexone reverses ethanol-induced dopamine release in the nucleus accumbens in awake, freely moving rats. Brain Res 621:137-140.
4. 11C]raclopride binding with continuous infusion. J Cereb Blood Flow Metab 17:437-47.
5. Cloninger CR. 1994. Temperament and personality. Curr Opin Neurobiol 4:266-273.
6. Cloninger CR, Sigvardsson S, Bohman M. 1988. Childhood personality predicts alcohol abuse in young adults. Alcohol Clin Exp Res 12:494-505.
7. Cloninger CR, Przybeck TR, Svrakic DM. 1991. The tridimensional personality questionnaire: U.S. normative data. Psychol Rep 69:1047-1057.
8. Collins DL, Neelin P, Peters TM, Evans AC. 1994. Automatic 3D intersubject registration of MR volumetric data in standardized Talairach space. J Comput Assist Tomogr 18:192-205.
9. Conrod PJ, Peterson JB, Pihl RO. 2001. Reliability and validity of alcohol-induced heart rate increase as a measure of sensitivity to the stimulant properties of alcohol. Psychopharmacology 157:20-30.
10. Diana M, Pistis M, Muntoni A, Rossetti ZL, Gessa G. 1992. Marked decrease of A10 dopamine neuronal firing during ethanol withdrawal syndrome in rats. Eur J Pharmacol 221:403-404.
11. Di Chiara G, Imperato A. 1988. Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. Proc Natl Acad Sci 85:5274-5278.
12. Di Chiara G, Tanda G, Bassareo V, Pontieri F, Acquas E, Fenu S, Cadoni C, Carboni E. 1999. Drug addiction as a disorder of associative learning. Role of nucleus accumbens shell/extended amygdala dopamine. Ann NY Acad Sci 877:461-485.
13. Drevets WC, Gautier C, Price JC, Kupfer DJ, Kinahan PE, Grace AA, Price JL, Mathis CA. 2001. Amphetamine-induced dopamine release in human ventral striatum correlates with euphoria. Biol Psychiatry 49:81-96
14. 11C]raclopride: combined PET-microdialysis studies. J Cereb Blood Flow Metab 17:932-942.
15. Everitt BJ, Morris KA, O'Brien A, Robbins TW. 1991. The basolateral amygdala-ventral striatal system and conditioned place preference: further evidence of limbic-striatal interactions underlying reward-related processes. Neuroscience 42:1-18.
16. Gatto GJ, McBride WJ, Murphy JM, Lumeng L, Li TK. 1994. Ethanol self-infusion into the ventral tegmental area by alcohol-preferring rats. Alcohol 11:557-564.
17. Gessa GL, Muntoni F, Collu M, Vargiu L, Mereu G. 1985. Low doses of ethanol activate dopaminergic neurons in the ventral tegmental area. Brain Res 348:201-203.
18. 11C]raclopride binding to D2-dopamine receptors in the monkey brain. Synapse 25:321-325.
19. Gonzales RA, Weiss F. 1998. Suppression of ethanol-reinforced behaviour by naltrexone is associated with attenuation of the ethanol-induced increase in dialysate dopamine levels in the nucleus accumbens. J Neurosci 18:10663-10671.
20. Grace AA, Bunney BS. 1985. Opposing effects of striatonigral feedback pathways on midbrain dopamine cell activity. Brain Res 333:271-284.
21. Gunn RN, Lammertsma AA, Hume SP, Cunningham VJ. 1997. Parametric imaging of ligand-receptor binding in PET using a simplified reference region model. Neuroimage 6:279-287.
22. Haber SN, Fudge JL, McFarland NR. 2000. Striatonigrostriatal pathways in primates form an ascending spiral from the shell to the dorsolateral striatum. J Neurosci 20:2369-2382.
23. Hartvig P, Torstenson R, Tedroff J, Watanabe Y, Fasth KJ, Bjurling P, Langstrom B. 1997. Amphetamine effects on dopamine release and synthesis rate studied in the rhesus monkey brain by positron emission tomography. J Neural Transm 104:329-339.
24. Heimer L, Switzer RD, Van Hoesen GW. 1982. Ventral striatum and ventral pallidum. Components of the motor system? Trends Neurosci 5:83-87.
25. Hiroi N, White NM. 1991. The amphetamine conditioned place preference: differential involvement of dopamine receptor subtypes and two dopaminergic terminal areas. Brain Res 552:141-152.
26. Hooks MS, Colvin AC, Juncos JL, Justice Jr JB. 1992. Individual differences in basal and cocaine-stimulated extracellular dopamine in the nucleus accumbens using quantitative microdialysis. Brain Res 587:306-312.
27. Judd LL, Hubbard B, Janowsky DS, Huey LY, Attewell PA. 1977. The effect of lithium carbonate on affect, mood, and personality of normal subjects. Arch Gen Psychiatry 34:346-351.
28. Katner SN, Weiss F. 1999. Ethanol-associated olfactory stimuli reinstate ethanol-seeking behavior after extinction and modify extra-cellular dopamine levels in the nucleus accumbens. Alcohol Clin Exp Res 23:1751-1760.
29. Koepp MJ, Gunn RN, Lawrence AD, Cunningham VJ, Dagher A, Jones T, Brooks DJ, Bench CJ, Grasby PM. 1998. Evidence for striatal dopamine release during a video game. Nature 393:266-268.
30. Koob GF, Sanna PP, Bloom FE. 1998. Neuroscience of addiction. Neuron 21:467-476.
31. Lammertsma AA, Hume SP. 1996. Simplified Reference Tissue Model for PET Receptor Studies. Neuroimage 4:153-158.
32. Laruelle M. 2000. Imaging synaptic neurotransmission with in vivo binding competition techniques: a critical review. J Cereb Blood Flow Metab 20:423-451.
33. Laruelle M, Iyer RN, al-Tikriti MS, Zea-Ponce Y, Malison R, Zoghbi SS, Baldwin RM, Kung HF, Charney DS, Hoffer PB, Innis RB, Bradberry CW. 1997. Microdialysis and SPECT measurements of amphetamine-induced dopamine release in nonhuman primates. Synapse 25:1-14.
34. Leyton M, Boileau I, Benkelfat C, Diksic M, Baker G, Dagher A. 2002. Amphetamine-induced increases in extracellular dopamine, drug wanting and novelty seeking: A PET/[11C]raclopride study in healthy men. Neuropsychopharmacology 27:1027-1035.
35. Marinelli M, White FJ. 2000. Enhanced vulnerability to cocaine self-administration is associated with elevated impulse activity of midbrain dopamine neurons. J Neurosci 20:8876-8885.
36. Martinez D, Slifstein M, Broft A, Mawlawi O, Hwang DR, Huang Y, Cooper T, Kegeles L, Zarahn E, Abi-Dargham A, Haber SN, Laruelle M. 2003. Imaging human mesolimbic dopamine transmission with positron emission tomography. II. Amphetamine-induced dopamine release in the functional subdivisions of the striatum. J Cereb Blood Flow Metab 23:285-300.
37. Mereu G, Gessa GL. 1985. Low doses of ethanol inhibit the firing of neurons in the substantia nigra, pars reticulata: a GABAergic effect? Brain Res 360:325-330.
38. Meszaros K, Lenzinger E, Hornik K, Fureder T, Willinger U, Fischer G, Schonbeck G, Aschauer HN. 1999. The Tridimensional Personality Questionnaire as a predictor of relapse in detoxified alcohol dependents. The European Fluvoxamine in Alcoholism Study Group. Alcohol Clin Exp Res 23:483-486.
39. Moore RY, Bloom FE. 1978. Central catecholamine neuron systems: anatomy and physiology of the dopamine systems. Annu Rev Neurosci 1:129-169.
40. Nowak KL, McBride WJ, Lumeng L, Li TK, Murphy JM. 2000. Involvement of dopamine D2 autoreceptors in the ventral tegmental area on alcohol and saccharin intake of the alcohol-preferring P rat. Alcohol Clin Exp Res 24:476-483.
41. Piazza PV, Rouge-Pont F, Deminiere JM, Kharoubi M, Le Moal M, Simon H. 1991. Dopaminergic activity is reduced in the prefrontal cortex and increased in the nucleus accumbens of rats predisposed to develop amphetamine self-administration. Brain Res 567:169-174.
42. Pokorny AD, Miller BA, Kaplan HB. 1972. The brief MAST: a shortened version of the Michigan Alcoholism Screening Test. Am J Psychiatry 129:342-345.
43. Rassnick S, Stinus L, Koob GF. 1993. The effects of 6-hydroxydopamine lesions of the nucleus accumbens and the mesolimbic dopamine system on oral self-administration of ethanol in the rat. Brain Res 623:16-24.
44. Rossetti ZL, Hmaidan Y, Gessa GL. 1992. Marked inhibition of mesolimbic dopamine release: a common feature of ethanol, morphine, cocaine and amphetamine abstinence in rats. Eur J Pharmacol 221:227-234.
45. Samson HH, Hodge CW, Tolliver GA, Haraguchi M. 1993. Effect of dopamine agonists and antagonists on ethanol-reinforced behaviour: the involvement of the nucleus accumbens. Brain Res Bull 30:133-141.
46. Schlaepfer TE, Pearlson GD, Wong DF, Marenco S, Dannals RF. 1997. PET study of competition between intravenous cocaine and [11C] raclopride at dopamine receptors in human subjects. Am J Psychiatry 154:1209-1213.
47. Schuckit MA, Tipp JE, Smith TL, Wiesbeck GA, Kalmijn J. 1997. The relationship between self-rating of the effects of alcohol and alcohol challenge results in ninety-eight young men. J Stud Alcohol 58:397-404.
48. Stormark KM, Laberg JC, Bjerland T, Nordby H, Hugdahl K. 1995. Autonomic cued reactivity in alcoholics: the effect of olfactory stimuli. Addict Behav 20:571-584.
49. Talairach J, Tournoux P. 1988. Co-planar stereotaxic atlas of the human brain. Stuttgart: Thieme.
50. Tremblay RE, Pihl RO, Vitaro F, Dobkin PL. 1994. Predicting early onset of male antisocial behaviour from preschool behaviour. Arch Gen Psychiatry 51:732-739.
51. Volkow ND, Wang G, Fowler JS, Logan J, Gerasimov M, Maynard L, Ding Y, Gatley SJ, Gifford A, Franceschi D. 2001. Therapeutic doses of oral methylphenidate significantly increase extracellular dopamine in the human brain. J Neurosci 21:RC121.
52. Weiner JL, Zhang L, Carlen PL. 1994. Potentiation of GABAA-mediated synaptic current by ethanol in hippocampal CA1 neurons: possible role of protein kinase C. J Pharmacol Exp Ther 268:1388-1395.
53. Weiss F, Lorang MT, Bloom FE, Koob GF. 1993. Oral alcohol self-administration stimulates dopamine release in the rat nucleus accumbens: genetic and motivational determinants. J Pharmacol Exp Ther 267:250-258.
54. Weiss F, Parsons LH, Schulteis G, Hyytia P, Lorang MT, Bloom FE, Koob GF . 1996. Ethanol self-administration restores withdrawal-associated deficiencies in accumbal dopamine and 5-hydroxytryptamine release in dependent rats. J Neurosci 16:3474-3485.
55. Wise RA. 1996. Neurobiology of addiction. Curr Opin Neurobiol 6:243-251.
56. Woods RP, Mazziotta JC, Cherry SR. 1993. MRI-PET registration with automated algorithm. J Comput Assist Tomogr 17:536-546.
57. Yim HJ, Schallert T, Randall PK, Gonzales RA. 1998. Comparison of local and systemic ethanol effects on extracellular dopamine concentration in rat nucleus accumbens by microdialysis. Alcohol Clin Exp Res 22:2367-2374.
58. Zocchi A, Orsini C, Cabib S, Puglisi-Allegra S. 1998. Parallel strain-dependent effect of amphetamine on locomotor activity and dopamine release in the nucleus accumbens: an in vivo study in mice. Neuroscience 82:521-528.