메뉴 건너뛰기




Volumn 17, Issue 1, 2012, Pages 86-94

Ghrelin receptor (GHS-R1A) antagonism suppresses both operant alcohol self-administration and high alcohol consumption in rats

Author keywords

AA rats; alcohol; ethanol; ghrelin receptors; motivation; operant self administration

Indexed keywords

ALCOHOL; GHRELIN RECEPTOR; HORMONE RECEPTOR BLOCKING AGENT; JMV 2959; UNCLASSIFIED DRUG;

EID: 84255177243     PISSN: 13556215     EISSN: 13691600     Source Type: Journal    
DOI: 10.1111/j.1369-1600.2010.00280.x     Document Type: Article
Times cited : (96)

References (56)
  • 3
    • 0036073405 scopus 로고    scopus 로고
    • Extent and direction of ghrelin transport across the blood-brain barrier is determined by its unique primary structure
    • DOI 10.1124/jpet.102.034827
    • Banks WA, Tschöp M, Robinson SM, Heiman ML, (2002) Extent and direction of ghrelin transport across the blood-brain barrier is determined by its unique primary structure. J Pharmacol Exp Ther 302: 822-827. (Pubitemid 34787253)
    • (2002) Journal of Pharmacology and Experimental Therapeutics , vol.302 , Issue.2 , pp. 822-827
    • Banks, W.A.1    Tschop, M.2    Robinson, S.M.3    Heiman, M.L.4
  • 5
    • 0018748828 scopus 로고
    • Food deprivation increases oral and intravenous drug intake in rats
    • Carroll ME, France CP, Meisch RA, (1979) Food deprivation increases oral and intravenous drug intake in rats. Science 205: 319-321. (Pubitemid 9228354)
    • (1979) Science , vol.205 , Issue.4403 , pp. 319-321
    • Carroll, M.E.1    France, C.P.2    Meisch, R.A.3
  • 7
    • 33947157380 scopus 로고    scopus 로고
    • Augmented cocaine conditioned place preference in rats pretreated with systemic ghrelin
    • DOI 10.1016/j.regpep.2006.12.003, PII S0167011506002400
    • Davis KW, Wellman PJ, Clifford PS, (2007) Augmented cocaine conditioned place preference in rats pretreated with systemic ghrelin. Regul Pept 140: 148-152. (Pubitemid 46418913)
    • (2007) Regulatory Peptides , vol.140 , Issue.3 , pp. 148-152
    • Davis, K.W.1    Wellman, P.J.2    Clifford, P.S.3
  • 10
    • 0000906259 scopus 로고
    • Genetic selection for voluntary alcohol consumption in the albino rat
    • Eriksson K, (1968) Genetic selection for voluntary alcohol consumption in the albino rat. Science 159: 739-741.
    • (1968) Science , vol.159 , pp. 739-741
    • Eriksson, K.1
  • 11
    • 0014998976 scopus 로고
    • Rat strains specially selected for their voluntary alcohol consumption
    • Eriksson K, (1971) Rat strains specially selected for their voluntary alcohol consumption. Ann Med Exp Biol Fenn 49: 67-72.
    • (1971) Ann Med Exp Biol Fenn , vol.49 , pp. 67-72
    • Eriksson, K.1
  • 12
    • 0041820129 scopus 로고    scopus 로고
    • Hyperphagic effects of brainstem ghrelin administration
    • DOI 10.2337/diabetes.52.9.2260
    • Faulconbridge LF, Cummings DE, Kaplan JM, Grill HJ, (2003) Hyperphagic effects of brainstem ghrelin administration. Diabetes 52: 2260-2265. (Pubitemid 37059495)
    • (2003) Diabetes , vol.52 , Issue.9 , pp. 2260-2265
    • Faulconbridge, L.F.1    Cummings, D.E.2    Kaplan, J.M.3    Grill, H.J.4
  • 16
    • 0242330291 scopus 로고    scopus 로고
    • High Constitutive Signaling of the Ghrelin Receptor - Identification of a Potent Inverse Agonist
    • DOI 10.1210/me.2003-0069
    • Holst B, Cygankiewicz A, Jensen TH, Ankersen M, Schwartz TW, (2003) High constitutive signaling of the ghrelin receptor-identification of a potent inverse agonist. Mol Endocrinol 17: 2201-2210. (Pubitemid 37352532)
    • (2003) Molecular Endocrinology , vol.17 , Issue.11 , pp. 2201-2210
    • Holst, B.1    Cygankiewicz, A.2    Jensen, T.H.3    Ankersen, M.4    Schwartz, T.W.5
  • 17
    • 49349099488 scopus 로고    scopus 로고
    • Systemic administration of ghrelin induces conditioned place preference and stimulates accumbal dopamine
    • Jerlhag E, (2008) Systemic administration of ghrelin induces conditioned place preference and stimulates accumbal dopamine. Addict Biol 13: 358-363.
    • (2008) Addict Biol , vol.13 , pp. 358-363
    • Jerlhag, E.1
  • 18
    • 33748362868 scopus 로고    scopus 로고
    • Ghrelin stimulates locomotor activity and accumbal dopamine-overflow via central cholinergic systems in mice: Implications for its involvement in brain reward
    • DOI 10.1111/j.1369-1600.2006.00002.x
    • Jerlhag E, Egecioglu E, Dickson SL, Andersson M, Svensson L, Engel JA, (2006) Ghrelin stimulates locomotor activity and accumbal dopamine overflow via central cholinergic mechanisms: implications for its involvement in brain reward. Addict Biol 11: 45-54. (Pubitemid 46696736)
    • (2006) Addiction Biology , vol.11 , Issue.1 , pp. 45-54
    • Jerlhag, E.1    Egecioglu, E.2    Dickson, S.L.3    Andersson, M.4    Svensson, L.5    Engel, J.A.6
  • 19
    • 33947139281 scopus 로고    scopus 로고
    • Ghrelin administration into tegmental areas stimulates locomotor activity and increases extracellular concentration of dopamine in the nucleus accumbens
    • DOI 10.1111/j.1369-1600.2006.00041.x
    • Jerlhag E, Egecioglu E, Dickson SL, Douhan A, Svensson L, Engel JA, (2007) Ghrelin administration into tegmental areas ghrelin administration stimulates locomotor activity and increases extracellular concentration of dopamine in the nucleus accumbens. Addict Biol 12: 6-16. (Pubitemid 46405994)
    • (2007) Addiction Biology , vol.12 , Issue.1 , pp. 6-16
    • Jerlhag, E.1    Egecioglu, E.2    Dickson, S.L.3    Douhan, A.4    Svensson, L.5    Engel, J.A.6
  • 20
    • 79955957550 scopus 로고    scopus 로고
    • Glutamatergic regulation of ghrelin-induced activation of the mesolimbic dopamine system
    • [Epub ahead of print]
    • Jerlhag E, Egecioglu E, Dickson SL, Engel JA, (2010a) Glutamatergic regulation of ghrelin-induced activation of the mesolimbic dopamine system. Addict Biol [Epub ahead of print].
    • (2010) Addict Biol
    • Jerlhag, E.1    Egecioglu, E.2    Dickson, S.L.3    Engel, J.A.4
  • 21
    • 77955512728 scopus 로고    scopus 로고
    • Ghrelin receptor antagonism attenuates cocaine- and amphetamine-induced locomotor stimulation, accumbal dopamine release, and conditioned place preference
    • [Epub ahead of print]
    • Jerlhag E, Egecioglu E, Dickson SL, Engel JA, (2010b) Ghrelin receptor antagonism attenuates cocaine- and amphetamine-induced locomotor stimulation, accumbal dopamine release, and conditioned place preference. Psychopharmacology (Berl) [Epub ahead of print].
    • (2010) Psychopharmacology (Berl)
    • Jerlhag, E.1    Egecioglu, E.2    Dickson, S.L.3    Engel, J.A.4
  • 22
    • 44249109981 scopus 로고    scopus 로고
    • Alpha-conotoxin MII-sensitive nicotinic acetylcholine receptors are involved in mediating locomotor stimulatory and dopamine enhancing properties of ghrelin
    • Jerlhag E, Egecioglu E, Dickson SL, Svensson L, Engel JA, (2008) Alpha-conotoxin MII-sensitive nicotinic acetylcholine receptors are involved in mediating locomotor stimulatory and dopamine enhancing properties of ghrelin. Eur Neuropsychopharmacol 18: 508-518.
    • (2008) Eur Neuropsychopharmacol , vol.18 , pp. 508-518
    • Jerlhag, E.1    Egecioglu, E.2    Dickson, S.L.3    Svensson, L.4    Engel, J.A.5
  • 24
    • 33746583963 scopus 로고    scopus 로고
    • Ghrelin amplifies dopamine signaling by cross talk involving formation of growth hormone secretagogue receptor/dopamine receptor subtype 1 heterodimers
    • DOI 10.1210/me.2005-0084
    • Jiang H, Betancourt L, Smith RG, (2006) Ghrelin amplifies dopamine signaling by cross talk involving formation of growth hormone secretagogue receptor/dopamine receptor subtype 1 heterodimers. Mol Endocrinol 20: 1772-1785. (Pubitemid 44148083)
    • (2006) Molecular Endocrinology , vol.20 , Issue.8 , pp. 1772-1785
    • Jiang, H.1    Betancourt, L.2    Smith, R.G.3
  • 26
    • 36849038927 scopus 로고    scopus 로고
    • Approach to the genetics of alcoholism: A review based on pathophysiology
    • DOI 10.1016/j.bcp.2007.06.021, PII S0006295207003826, Addiction
    • Köhnke MD, (2008) Approach to the genetics of alcoholism: a review based on pathophysiology. Biochem Pharmacol 75: 160-177. (Pubitemid 350235389)
    • (2008) Biochemical Pharmacology , vol.75 , Issue.1 , pp. 160-177
    • Kohnke, M.D.1
  • 30
    • 1042274886 scopus 로고    scopus 로고
    • Neurochemical and behavioral studies on ethanol and nicotine interactions
    • DOI 10.1016/j.neubiorev.2003.11.010
    • Larsson A, Engel JA, (2004) Neurochemical and behavioral studies on ethanol and nicotine interactions. Neurosci Biobehav Rev 27: 713-720. (Pubitemid 38202247)
    • (2004) Neuroscience and Biobehavioral Reviews , vol.27 , Issue.8 , pp. 713-720
    • Larsson, A.1    Engel, J.A.2
  • 32
    • 11144310116 scopus 로고    scopus 로고
    • Identification of ghrelin and its receptor in neurons of the rat arcuate nucleus
    • DOI 10.1016/j.regpep.2004.08.038, PII S0167011504002964
    • Mondal MS, Date Y, Yamaguxhi H, Toshinai K, Tsuruta T, Kangawa K, Nakazato M, (2005) Identification of ghelin and its receptor in neurons of the rat arcuate nucleus. Regul Pept 126: 55-59. (Pubitemid 40037743)
    • (2005) Regulatory Peptides , vol.126 , Issue.1-2 , pp. 55-59
    • Mondal, M.S.1    Date, Y.2    Yamaguchi, H.3    Toshinai, K.4    Tsuruta, T.5    Kangawa, K.6    Nakazato, M.7
  • 34
    • 27744593324 scopus 로고    scopus 로고
    • Ghrelin induces feeding in the mesolimbic reward pathway between the ventral tegmental area and the nucleus accumbens
    • DOI 10.1016/j.peptides.2005.04.025, PII S0196978105003505
    • Naleid AM, Grace MK, Cummings DE, Levine AS, (2005) Ghrelin induces feeding in the mesolimbic reward pathway between the ventral tegmental area and the nucleus accumbens. Peptides 26: 2274-2279. (Pubitemid 41584095)
    • (2005) Peptides , vol.26 , Issue.11 , pp. 2274-2279
    • Naleid, A.M.1    Grace, M.K.2    Cummings, D.E.3    Levine, A.S.4
  • 35
    • 33745067777 scopus 로고    scopus 로고
    • Growth hormone secretagogue (Ghrelin-) receptors - A complex drug target for the regulation of body weight
    • Nogueiras R, Perez-Tilve D, Wortley KE, Tschöp M, (2006) Growth hormone secretagogue (ghrelin-) receptors-a complex drug target for the regulation of body weight. CNS Neurol Disord Drug Targets 5: 335-343. (Pubitemid 43881014)
    • (2006) CNS and Neurological Disorders - Drug Targets , vol.5 , Issue.3 , pp. 335-343
    • Nogueiras, R.1    Perez-Tilve, D.2    Wortley, K.E.3    Tschop, M.4
  • 36
    • 60249087415 scopus 로고    scopus 로고
    • Systemic administration of ghrelin increases extracellular dopamine in the shell but not the core subdivision of the nucleus accumbens
    • Quarta D, Di Francesco C, Melotto S, Mangiarini L, Heidbreder C, Hedou G, (2009) Systemic administration of ghrelin increases extracellular dopamine in the shell but not the core subdivision of the nucleus accumbens. Neurochem Int 54: 89-94.
    • (2009) Neurochem Int , vol.54 , pp. 89-94
    • Quarta, D.1    Di Francesco, C.2    Melotto, S.3    Mangiarini, L.4    Heidbreder, C.5    Hedou, G.6
  • 37
    • 13244279633 scopus 로고    scopus 로고
    • Pathological gambling is linked to reduced activation of the mesolimbic reward system
    • DOI 10.1038/nn1378
    • Reuter J, Raedler T, Rose M, Hand I, Glascher J, Buchel C, (2005) Pathological gambling is linked to reduced activation of the mesolimbic reward system. Nat Neurosci 8: 147-148. (Pubitemid 40194043)
    • (2005) Nature Neuroscience , vol.8 , Issue.2 , pp. 147-148
    • Reuter, J.1    Raedler, T.2    Rose, M.3    Hand, I.4    Glascher, J.5    Buchel, C.6
  • 38
    • 11844289551 scopus 로고    scopus 로고
    • Evaluation of a simple model of ethanol drinking to intoxication in C57BL/6J mice
    • DOI 10.1016/j.physbeh.2004.10.007, PII S0031938404004585
    • Rhodes JS, Best K, Belknap JK, Finn DA, Crabbe JC, (2005) Evaluation of a simple model of ethanol drinking to intoxication in C57BL/6J mice. Physiol Behav 84: 53-63. (Pubitemid 40092065)
    • (2005) Physiology and Behavior , vol.84 , Issue.1 , pp. 53-63
    • Rhodes, J.S.1    Best, K.2    Belknap, J.K.3    Finn, D.A.4    Crabbe, J.C.5
  • 39
    • 0027305458 scopus 로고
    • The neural basis of drug craving: An incentive-sensitization theory of addiction
    • DOI 10.1016/0165-0173(93)90013-P
    • Robinson TE, Berridge KC, (1993) The neural basis of drug craving: an incentive-sensitization theory of addiction. Brain Res Brain Res Rev 18: 247-291. (Pubitemid 23219500)
    • (1993) Brain Research Reviews , vol.18 , Issue.3 , pp. 247-291
    • Robinson, T.E.1    Berridge, K.C.2
  • 43
    • 77952419292 scopus 로고    scopus 로고
    • Long-Evans rats acquire operant self-administration of 20% ethanol without sucrose fading
    • Simms JA, Bito-Onon JJ, Chatterjee S, Bartlett SE, (2010) Long-Evans rats acquire operant self-administration of 20% ethanol without sucrose fading. Neuropsychopharmacology 35: 1453-1463.
    • (2010) Neuropsychopharmacology , vol.35 , pp. 1453-1463
    • Simms, J.A.1    Bito-Onon, J.J.2    Chatterjee, S.3    Bartlett, S.E.4
  • 48
    • 33947146710 scopus 로고    scopus 로고
    • Correlation between serum ghrelin levels and cocaine-seeking behaviour triggered by cocaine-associated conditioned stimuli in rats
    • DOI 10.1111/j.1369-1600.2007.00052.x
    • Tessari M, Catalano A, Pellitteri M, Di Francesco C, Marini F, Gerrard PA, Heidbreder CA, Melotto S, (2007) Correlation between serum ghrelin levels and cocaine-seeking behaviour triggered by cocaine associated conditioned stimulus in rats. Addict Biol 12: 22-29. (Pubitemid 46406004)
    • (2007) Addiction Biology , vol.12 , Issue.1 , pp. 22-29
    • Tessari, M.1    Catalano, A.2    Pellitteri, M.3    Di Francesco, C.4    Marini, F.5    Gerrard, P.A.6    Heidbreder, C.A.7    Melotto, S.8
  • 49
    • 9944237306 scopus 로고    scopus 로고
    • Drug addiction: The neurobiology of behaviour gone awry
    • DOI 1038/nrn1539
    • Volkow ND, Li TK, (2004) Drug addiction: the neurobiology of behaviour gone awry. Nat Rev Neurosci 5: 963-970. (Pubitemid 39593359)
    • (2004) Nature Reviews Neuroscience , vol.5 , Issue.12 , pp. 963-970
    • Volkow, N.D.1    Li, T.-K.2
  • 52
    • 9944233963 scopus 로고    scopus 로고
    • Augmentation of cocaine hyperactivity in rats by systemic ghrelin
    • DOI 10.1016/j.regpep.2004.08.013, PII S0167011504003015
    • Wellman PJ, Davis KW, Nation JR, (2005) Augmentation of cocaine hyperactivity in rats by systemic ghrelin. Regul Pept 125: 151-154. (Pubitemid 39593719)
    • (2005) Regulatory Peptides , vol.125 , Issue.1-3 , pp. 151-154
    • Wellman, P.J.1    Davis, K.W.2    Nation, J.R.3
  • 53
    • 0015543606 scopus 로고
    • Voluntary ethanol intake in rats following exposure to ethanol on various schedules
    • Wise RA, (1973) Voluntary ethanol intake in rats following exposure to ethanol on various schedules. Psychopharmacologia 29: 203-210.
    • (1973) Psychopharmacologia , vol.29 , pp. 203-210
    • Wise, R.A.1
  • 54
    • 0023426876 scopus 로고
    • A psychomotor stimulant theory of addiction
    • Wise RA, Bozarth MA, (1987) A psychomotor stimulant theory of addiction. Psychol Rev 94: 469-492.
    • (1987) Psychol Rev , vol.94 , pp. 469-492
    • Wise, R.A.1    Bozarth, M.A.2
  • 56
    • 33947105623 scopus 로고    scopus 로고
    • Alcohol administration acutely inhibits ghrelin secretion in an experiment involving psychosocial stress
    • DOI 10.1111/j.1369-1600.2006.00026.x
    • Zimmermann US, Buchmann A, Steffin B, Dieterle C, Uhr M, (2007) Alcohol administration acutely inhibits ghrelin secretion in an experiment involving psychosocial stress. Addict Biol 12: 17-21. (Pubitemid 46405991)
    • (2007) Addiction Biology , vol.12 , Issue.1 , pp. 17-21
    • Zimmermann, U.S.1    Buchmann, A.2    Steffin, B.3    Dieterle, C.4    Uhr, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.