Structural mechanism for the recognition and ubiquitination of a single nucleosome residue by Rad6-Bre1

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 38, 2016, Pages 10553-10558

  Gallego, Laura D ^a   Steger, Medini Ghodgaonkar ^b   Polyansky, Anton A ^c   Schubert, Tobias ^a   Zagrovic, Bojan ^c   Zheng, Ning ^d,e   Clausen, Tim ^f   Herzog, Franz ^b   Köhler, Alwin ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b UNIVERSITY OF MUNICH   (Germany)

^c UNIVERSITY OF VIENNA   (Austria)

^d UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF WASHINGTON   (United States)

^f RESEARCH INSTITUTE OF MOLECULAR PATHOLOGY   (Austria)

Author keywords

Bre1 Rad6; Cross linking mass spectrometry; Nucleosome; RING E3 ligase; Ubiquitin

Indexed keywords

ACYLTRANSFERASE; BRE1 PROTEIN; DEUBIQUITINASE; HISTONE H2A; HISTONE H2B; LATENCY ASSOCIATED NUCLEAR ANTIGEN; LYSINE; RAD6 PROTEIN; UBIQUITIN CONJUGATING ENZYME E2; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; BRE1 PROTEIN, S CEREVISIAE; HISTONE; RAD6 PROTEIN, S CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEIN; UBIQUITIN; UBIQUITIN CONJUGATING ENZYME; UBIQUITIN PROTEIN LIGASE;

ARTICLE; ENZYME ACTIVATION; ENZYME ACTIVITY; MASS SPECTROMETRY; NONHUMAN; NUCLEOSOME; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CROSS LINKING; PROTEIN STRUCTURE; STATIC ELECTRICITY; UBIQUITINATION; YEAST; CHEMISTRY; GENE EXPRESSION REGULATION; GENETICS; HUMAN; MOLECULAR DOCKING; PROTEIN CONFORMATION; SACCHAROMYCES CEREVISIAE;

GENE EXPRESSION REGULATION, ENZYMOLOGIC; HISTONES; HUMANS; MOLECULAR DOCKING SIMULATION; NUCLEOSOMES; PROTEIN CONFORMATION; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; UBIQUITIN; UBIQUITIN-CONJUGATING ENZYMES; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84988664609     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1606863113     Document Type: Article

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