Monoubiquitination of histone H2B is intrinsic to the Bre1 RING domain-Rad6 interaction and augmented by a second Rad6-binding site on Bre1

Journal of Biological Chemistry

Volumn 290, Issue 9, 2015, Pages 5298-5310

  Turco, Eleonora ^a   Gallego, Laura D ^a   Schneider, Maren ^a   Köhler, Alwin ^a  

^a MAX F PERUTZ LABORATORIES   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; AMINO ACIDS; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENES; TRANSCRIPTION;

BINDING DOMAIN; CHARGED RESIDUES; DOMAIN INTERACTIONS; LYSINE RESIDUES; MOLECULAR FRAMEWORKS; NUCLEOSOME SURFACE; NUCLEOSOMES; SUBSTRATE SELECTION;

PROTEINS;

E2 RAD6; E3 LIGASE BRE1; HISTONE H2B; UBIQUITIN CONJUGATING ENZYME E2; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; BRE1 PROTEIN, S CEREVISIAE; HISTONE; LYSINE; NUCLEOSOME; PROTEIN BINDING; RAD6 PROTEIN, S CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEIN; UBIQUITIN; UBIQUITIN CONJUGATING ENZYME;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; BRE1 GENE; BRE1 RING DOMAIN; CATALYSIS; COMPARATIVE STUDY; CONTROLLED STUDY; DNA REPAIR; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; FUNGAL CELL; GENE; GENE DELETION; GENE EXPRESSION REGULATION; HISTONE MONOUBIQUITINATION; HISTONE UBIQUITINATION; IN VITRO STUDY; MOLECULAR BIOLOGY; MOLECULAR DYNAMICS; MOLECULAR WEIGHT; NONHUMAN; NUCLEOSOME RECOGNITION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; RAD6 BINDING DOMAIN; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; UBIQUITIN TRANSFER; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; IMMUNOBLOTTING; METABOLISM; MOLECULAR GENETICS; MUTATION; NUCLEOSOME; PROTEIN TERTIARY STRUCTURE; SEQUENCE HOMOLOGY; UBIQUITINATION;

AMINO ACID SEQUENCE; BINDING SITES; HISTONES; IMMUNOBLOTTING; LYSINE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEOSOMES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY; UBIQUITIN; UBIQUITIN-CONJUGATING ENZYMES; UBIQUITINATION;

EID: 84923791955     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.626788     Document Type: Article

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