-
1
-
-
2542504498
-
The evolving diabetes burden in the United States
-
Engelgau MM, Geiss LS, Saaddine JB, Boyle JP, Benjamin SM, Gregg EW et al. The evolving diabetes burden in the United States. Ann Intern Med 2004; 140: 945–950.
-
(2004)
Ann Intern Med
, vol.140
, pp. 945-950
-
-
Engelgau, M.M.1
Geiss, L.S.2
Saaddine, J.B.3
Boyle, J.P.4
Benjamin, S.M.5
Gregg, E.W.6
-
2
-
-
0042484813
-
The obesity epidemic: Pathophysiology and consequences of obesity
-
Pi-Sunyer FX. The obesity epidemic: pathophysiology and consequences of obesity. Obes Res 2002; 10 (Suppl 2): 97S–104S.
-
(2002)
Obes Res
, vol.10
, pp. 97S-104S
-
-
Pi-Sunyer, F.X.1
-
3
-
-
33646432226
-
Overweight and obesity: Prevalence, consequences, and causes of a growing public health problem
-
Wyatt SB, Winters KP, Dubbert PM. Overweight and obesity: prevalence, consequences, and causes of a growing public health problem. Am J Med Sci 2006; 331: 166–174.
-
(2006)
Am J Med Sci
, vol.331
, pp. 166-174
-
-
Wyatt, S.B.1
Winters, K.P.2
Dubbert, P.M.3
-
4
-
-
0027536374
-
Risk factors for coronary heart disease mortality among persons with diabetes
-
DeStefano F, Ford ES, Newman J, Stevenson JM, Wetterhall SF, Anda RF et al. Risk factors for coronary heart disease mortality among persons with diabetes. Ann Epidemiol 1993; 3: 27–34.
-
(1993)
Ann Epidemiol
, vol.3
, pp. 27-34
-
-
Destefano, F.1
Ford, E.S.2
Newman, J.3
Stevenson, J.M.4
Wetterhall, S.F.5
Anda, R.F.6
-
5
-
-
27444437321
-
Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans
-
Cinti S, Mitchell G, Barbatelli G, Murano I, Ceresi E, Faloia E et al. Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans. J Lipid Res 2005; 46: 2347–2355.
-
(2005)
J Lipid Res
, vol.46
, pp. 2347-2355
-
-
Cinti, S.1
Mitchell, G.2
Barbatelli, G.3
Murano, I.4
Ceresi, E.5
Faloia, E.6
-
6
-
-
0348230958
-
Obesity is associated with macrophage accumulation in adipose tissue
-
Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, Ferrante AW Jr. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 2003; 112: 1796–1808.
-
(2003)
J Clin Invest
, vol.112
, pp. 1796-1808
-
-
Weisberg, S.P.1
McCann, D.2
Desai, M.3
Rosenbaum, M.4
Leibel, R.L.5
Ferrante, A.W.6
-
7
-
-
33646572904
-
The metabolic syndrome and adipocytokines
-
Matsuzawa Y. The metabolic syndrome and adipocytokines. FEBS Lett 2006; 580: 2917–2921.
-
(2006)
FEBS Lett
, vol.580
, pp. 2917-2921
-
-
Matsuzawa, Y.1
-
8
-
-
33846263404
-
Adipocytokines—novel link between inflammation and vascular function?
-
Guzik TJ, Mangalat D, Korbut R. Adipocytokines—novel link between inflammation and vascular function? J Physiol Pharmacol 2006; 57: 505–528.
-
(2006)
J Physiol Pharmacol
, vol.57
, pp. 505-528
-
-
Guzik, T.J.1
Mangalat, D.2
Korbut, R.3
-
9
-
-
33645518035
-
Conditional and specific NF-kappaB blockade protects pancreatic beta cells from diabetogenic agents
-
Eldor R, Yeffet A, Baum K, Doviner V, Amar D, Ben-Neriah Y et al. Conditional and specific NF-kappaB blockade protects pancreatic beta cells from diabetogenic agents. Proc Natl Acad Sci USA 2006; 103: 5072–5077.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 5072-5077
-
-
Eldor, R.1
Yeffet, A.2
Baum, K.3
Doviner, V.4
Amar, D.5
Ben-Neriah, Y.6
-
10
-
-
18644376240
-
Type 2 diabetes, insulin secretion and beta-cell mass
-
Ahren B. Type 2 diabetes, insulin secretion and beta-cell mass. Curr Mol Med 2005; 5: 275–286.
-
(2005)
Curr Mol Med
, vol.5
, pp. 275-286
-
-
Ahren, B.1
-
11
-
-
0036251569
-
Hepatotoxicity of commonly used drugs: Nonsteroidal anti-inflammatory drugs, antihypertensives, antidiabetic agents, anticonvulsants, lipid-lowering agents, psychotropic drugs
-
Chitturi S, George J. Hepatotoxicity of commonly used drugs: nonsteroidal anti-inflammatory drugs, antihypertensives, antidiabetic agents, anticonvulsants, lipid-lowering agents, psychotropic drugs. Semin Liver Dis 2002; 22: 169–183.
-
(2002)
Semin Liver Dis
, vol.22
, pp. 169-183
-
-
Chitturi, S.1
George, J.2
-
12
-
-
33646806766
-
Toxicology of oral antidiabetic medications
-
Spiller HA, Sawyer TS. Toxicology of oral antidiabetic medications. Am J Health Syst Pharm 2006; 63: 929–938.
-
(2006)
Am J Health Syst Pharm
, vol.63
, pp. 929-938
-
-
Spiller, H.A.1
Sawyer, T.S.2
-
13
-
-
0037291286
-
Safety and anti-inflammatory activity of curcumin: A component of tumeric (Curcuma longa)
-
Chainani-Wu N. Safety and anti-inflammatory activity of curcumin: a component of tumeric (Curcuma longa). J Altern Complement Med 2003; 9: 161–168.
-
(2003)
J Altern Complement Med
, vol.9
, pp. 161-168
-
-
Chainani-Wu, N.1
-
14
-
-
0034117911
-
Traditional Indian systems of medicine
-
Lodha R, Bagga A. Traditional Indian systems of medicine. Ann Acad Med Singapore 2000; 29: 37–41.
-
(2000)
Ann Acad Med Singapore
, vol.29
, pp. 37-41
-
-
Lodha, R.1
Bagga, A.2
-
15
-
-
30044446136
-
Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IkappaBal-pha kinase and Akt activation
-
Aggarwal S, Ichikawa H, Takada Y, Sandur SK, Shishodia S, Aggarwal BB. Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IkappaBal-pha kinase and Akt activation. Mol Pharmacol 2006; 69: 195–206.
-
(2006)
Mol Pharmacol
, vol.69
, pp. 195-206
-
-
Aggarwal, S.1
Ichikawa, H.2
Takada, Y.3
Sandur, S.K.4
Shishodia, S.5
Aggarwal, B.B.6
-
16
-
-
3042558087
-
Effect of curcumin on gelatinase A (MMP-2) activity in B16F10 melanoma cells
-
Banerji A, Chakrabarti J, Mitra A, Chatterjee A. Effect of curcumin on gelatinase A (MMP-2) activity in B16F10 melanoma cells. Cancer Lett 2004; 211: 235–242.
-
(2004)
Cancer Lett
, vol.211
, pp. 235-242
-
-
Banerji, A.1
Chakrabarti, J.2
Mitra, A.3
Chatterjee, A.4
-
17
-
-
20044386149
-
Mechanism of inhibition of ascites tumor growth in mice by curcumin is mediated by NF-kB and caspase activated DNase
-
Belakavadi M, Salimath BP. Mechanism of inhibition of ascites tumor growth in mice by curcumin is mediated by NF-kB and caspase activated DNase. Mol Cell Biochem 2005; 273: 57–67.
-
(2005)
Mol Cell Biochem
, vol.273
, pp. 57-67
-
-
Belakavadi, M.1
Salimath, B.P.2
-
18
-
-
0035838123
-
Curcumin, a natural product present in turmeric, decreases tumor growth but does not behave as an anticachectic compound in a rat model
-
Busquets S, Carbo N, Almendro V, Quiles MT, Lopez-Soriano FJ, Argiles JM. Curcumin, a natural product present in turmeric, decreases tumor growth but does not behave as an anticachectic compound in a rat model. Cancer Lett 2001; 167: 33–38.
-
(2001)
Cancer Lett
, vol.167
, pp. 33-38
-
-
Busquets, S.1
Carbo, N.2
Almendro, V.3
Quiles, M.T.4
Lopez-Soriano, F.J.5
Argiles, J.M.6
-
19
-
-
33646452164
-
Chemopreventive properties of curcumin
-
Campbell FC, Collett GP. Chemopreventive properties of curcumin. Fut Oncol 2005; 1: 405–414.
-
(2005)
Fut Oncol
, vol.1
, pp. 405-414
-
-
Campbell, F.C.1
Collett, G.P.2
-
20
-
-
33646492469
-
Inhibition of tel-omerase activity and induction of apoptosis by curcumin in K-562 cells
-
Chakraborty S, Ghosh U, Bhattacharyya NP, Bhattacharya RK, Roy M. Inhibition of tel-omerase activity and induction of apoptosis by curcumin in K-562 cells. Mutat Res 2006; 569: 81–90.
-
(2006)
Mutat Res
, vol.569
, pp. 81-90
-
-
Chakraborty, S.1
Ghosh, U.2
Bhattacharyya, N.P.3
Bhattacharya, R.K.4
Roy, M.5
-
21
-
-
30544439107
-
Curcumin inhibits human colon cancer cell growth by suppressing gene expression of epidermal growth factor receptor through reducing the activity of the transcription factor Egr-1
-
Chen A, Xu J, Johnson AC. Curcumin inhibits human colon cancer cell growth by suppressing gene expression of epidermal growth factor receptor through reducing the activity of the transcription factor Egr-1. Oncogene 2006; 25: 278–287.
-
(2006)
Oncogene
, vol.25
, pp. 278-287
-
-
Chen, A.1
Xu, J.2
Johnson, A.C.3
-
22
-
-
0035174504
-
Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions
-
Cheng AL, Hsu CH, Lin JK, Hsu MM, Ho YF, Shen TS et al. Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions. Anticancer Res 2001; 21: 2895–2900.
-
(2001)
Anticancer Res
, vol.21
, pp. 2895-2900
-
-
Cheng, A.L.1
Hsu, C.H.2
Lin, J.K.3
Hsu, M.M.4
Ho, Y.F.5
Shen, T.S.6
-
23
-
-
0037070201
-
Curcumin induces apoptosis in human breast cancer cells through p53-dependent Bax induction
-
Choudhuri T, Pal S, Agwarwal ML, Das T, Sa G. Curcumin induces apoptosis in human breast cancer cells through p53-dependent Bax induction. FEBS Lett 2002; 512: 334–340.
-
(2002)
FEBS Lett
, vol.512
, pp. 334-340
-
-
Choudhuri, T.1
Pal, S.2
Agwarwal, M.L.3
Das, T.4
Sa, G.5
-
24
-
-
0033969490
-
Curcumin-containing diet inhibits diethylnitrosamine-induced murine hepatocarcinogenesis
-
Chuang SE, Kuo ML, Hsu CH, Chen CR, Lin JK, Lai GM et al. Curcumin-containing diet inhibits diethylnitrosamine-induced murine hepatocarcinogenesis. Carcino-genesis 2000; 21: 331–335.
-
(2000)
Carcino-Genesis
, vol.21
, pp. 331-335
-
-
Chuang, S.E.1
Kuo, M.L.2
Hsu, C.H.3
Chen, C.R.4
Lin, J.K.5
Lai, G.M.6
-
25
-
-
0037908832
-
Modulation of inflammatory mediators by ibuprofen and curcumin treatment during chronic inflammation in rat
-
Banerjee M, Tripathi LM, Srivastava VM, Puri A, Shukla R. Modulation of inflammatory mediators by ibuprofen and curcumin treatment during chronic inflammation in rat. Immunopharmacol Immunotoxicol 2003; 25: 213–224.
-
(2003)
Immunopharmacol Immunotoxicol
, vol.25
, pp. 213-224
-
-
Banerjee, M.1
Tripathi, L.M.2
Srivastava, V.M.3
Puri, A.4
Shukla, R.5
-
26
-
-
0028928877
-
Curcumin, an anti-tumour promoter and anti-inflammatory agent, inhibits induction of nitric oxide synthase in activated macrophages
-
Brouet I, Ohshima H. Curcumin, an anti-tumour promoter and anti-inflammatory agent, inhibits induction of nitric oxide synthase in activated macrophages. Biochem Biophys Res Commun 1995; 206: 533–540.
-
(1995)
Biochem Biophys Res Commun
, vol.206
, pp. 533-540
-
-
Brouet, I.1
Ohshima, H.2
-
27
-
-
0029128319
-
Effects of three dietary phytochemicals from tea, rosemary and turmeric on inflammation-induced nitrite production
-
Chan MM, Ho CT, Huang HI. Effects of three dietary phytochemicals from tea, rosemary and turmeric on inflammation-induced nitrite production. Cancer Lett 1995; 96: 23–29.
-
(1995)
Cancer Lett
, vol.96
, pp. 23-29
-
-
Chan, M.M.1
Ho, C.T.2
Huang, H.I.3
-
28
-
-
14944372848
-
NSAID and antioxidant prevention of Alzheimer's disease: Lessons from in vitro and animal models
-
Cole GM, Morihara T, Lim GP, Yang F, Begum A, Frautschy SA. NSAID and antioxidant prevention of Alzheimer's disease: lessons from in vitro and animal models. Ann NY Acad Sci 2004; 1035: 68–84.
-
(2004)
Ann NY Acad Sci
, vol.1035
, pp. 68-84
-
-
Cole, G.M.1
Morihara, T.2
Lim, G.P.3
Yang, F.4
Begum, A.5
Frautschy, S.A.6
-
29
-
-
9744229172
-
Curcumin, the active constituent of turmeric, inhibits amyloid peptide-induced cytochemokine gene expression and CCR5-mediated chemotaxis of THP-1 monocytes by modulating early growth response-1 transcription factor
-
Giri RK, Rajagopal V, Kalra VK. Curcumin, the active constituent of turmeric, inhibits amyloid peptide-induced cytochemokine gene expression and CCR5-mediated chemotaxis of THP-1 monocytes by modulating early growth response-1 transcription factor. J Neurochem 2004; 91: 1199–1210.
-
(2004)
J Neurochem
, vol.91
, pp. 1199-1210
-
-
Giri, R.K.1
Rajagopal, V.2
Kalra, V.K.3
-
30
-
-
46349088791
-
Dietary curcumin significantly improves obesity-associated inflammation and diabetes in mouse models of diabesity
-
Weisberg SP, Leibel R, Tortoriello DV. Dietary curcumin significantly improves obesity-associated inflammation and diabetes in mouse models of diabesity. Endocrinology 2008; 149: 3549–3558.
-
(2008)
Endocrinology
, vol.149
, pp. 3549-3558
-
-
Weisberg, S.P.1
Leibel, R.2
Tortoriello, D.V.3
-
31
-
-
0032055394
-
Inhibition of nuclear factor kappaB by direct modification in whole cells—mechanism of action of nordihydroguaiaritic acid, curcumin and thiol modifiers
-
Brennan P, O'Neill LA. Inhibition of nuclear factor kappaB by direct modification in whole cells—mechanism of action of nordihydroguaiaritic acid, curcumin and thiol modifiers. Biochem Pharmacol 1998; 55: 965–973.
-
(1998)
Biochem Pharmacol
, vol.55
, pp. 965-973
-
-
Brennan, P.1
O'neill, L.A.2
-
32
-
-
13844306722
-
Activation of PPAR{gamma} by curcumin inhibits Moser cell growth and mediates suppression of gene expression of cyclin D1 and EGFR
-
Chen A, Xu J. Activation of PPAR{gamma} by curcumin inhibits Moser cell growth and mediates suppression of gene expression of cyclin D1 and EGFR. Am J Physiol Gastrointest Liver Physiol 2005; 288: G447–G456.
-
(2005)
Am J Physiol Gastrointest Liver Physiol
, vol.288
, pp. G447-G456
-
-
Chen, A.1
Xu, J.2
-
33
-
-
9444252295
-
Activation of PPARgamma is required for curcumin to induce apoptosis and to inhibit the expression of extracellular matrix genes in hepatic stellate cells in vitro
-
Zheng S, Chen A. Activation of PPARgamma is required for curcumin to induce apoptosis and to inhibit the expression of extracellular matrix genes in hepatic stellate cells in vitro. Biochem J 2004; 384: 149–157.
-
(2004)
Biochem J
, vol.384
, pp. 149-157
-
-
Zheng, S.1
Chen, A.2
-
34
-
-
0032996089
-
Curcumin inhibits cyclooxygenase-2 transcription in bile acid-and phorbol ester-treated human gastrointestinal epithelial cells
-
Zhang F, Altorki NK, Mestre JR, Subbaramaiah K, Dannenberg AJ. Curcumin inhibits cyclooxygenase-2 transcription in bile acid-and phorbol ester-treated human gastrointestinal epithelial cells. Carcinogenesis 1999; 20: 445–451.
-
(1999)
Carcinogenesis
, vol.20
, pp. 445-451
-
-
Zhang, F.1
Altorki, N.K.2
Mestre, J.R.3
Subbaramaiah, K.4
Dannenberg, A.J.5
-
35
-
-
0035976049
-
Specific inhibition of cyclooxygenase-2 (COX-2) expression by dietary curcumin in HT-29 human colon cancer cells
-
Goel A, Boland CR, Chauhan DP. Specific inhibition of cyclooxygenase-2 (COX-2) expression by dietary curcumin in HT-29 human colon cancer cells. Cancer Lett 2001; 172: 111–118.
-
(2001)
Cancer Lett
, vol.172
, pp. 111-118
-
-
Goel, A.1
Boland, C.R.2
Chauhan, D.P.3
-
36
-
-
0036081685
-
Novel approaches for colon cancer prevention by cyclooxygenase-2 inhibitors
-
Reddy BS, Rao CV. Novel approaches for colon cancer prevention by cyclooxygenase-2 inhibitors. J Environ Pathol Toxicol Oncol 2002; 21: 155–164.
-
(2002)
J Environ Pathol Toxicol Oncol
, vol.21
, pp. 155-164
-
-
Reddy, B.S.1
Rao, C.V.2
-
37
-
-
1842783105
-
Curcumin suppresses lipopolysaccharide-induced cyclooxygenase-2 expression by inhibiting activator protein 1 and nuclear factor kappab bindings in BV2 microglial cells
-
Kang G, Kong PJ, Yuh YJ, Lim SY, Yim SV, Chun W et al. Curcumin suppresses lipopolysaccharide-induced cyclooxygenase-2 expression by inhibiting activator protein 1 and nuclear factor kappab bindings in BV2 microglial cells. J Pharmacol Sci 2004; 94: 325–328.
-
(2004)
J Pharmacol Sci
, vol.94
, pp. 325-328
-
-
Kang, G.1
Kong, P.J.2
Yuh, Y.J.3
Lim, S.Y.4
Yim, S.V.5
Chun, W.6
-
38
-
-
0042825578
-
Nutritional and botanical modulation of the inflammatory cascade— eicosanoids, cyclooxygenases, and lipoxygenases—as an adjunct in cancer ther-apy
-
discussion
-
Wallace JM. Nutritional and botanical modulation of the inflammatory cascade— eicosanoids, cyclooxygenases, and lipoxygenases—as an adjunct in cancer ther-apy. Integr Cancer Ther 2002; 1: 7–37; discussion.
-
(2002)
Integr Cancer Ther
, vol.1
, pp. 7-37
-
-
Wallace, J.M.1
-
39
-
-
0032537814
-
Inhibition of the c-Jun N-terminal kinase (JNK) signaling pathway by curcumin
-
Chen YR, Tan TH. Inhibition of the c-Jun N-terminal kinase (JNK) signaling pathway by curcumin. Oncogene 1998; 17: 173–178.
-
(1998)
Oncogene
, vol.17
, pp. 173-178
-
-
Chen, Y.R.1
Tan, T.H.2
-
40
-
-
0034663060
-
The cJun N-terminal kinase (JNK) signaling pathway mediates induction of urokinase-type plasmino-gen activator (uPA) by the alkylating agent MNNG
-
Parra M, Lluis F, Miralles F, Caelles C, Munoz-Canoves P. The cJun N-terminal kinase (JNK) signaling pathway mediates induction of urokinase-type plasmino-gen activator (uPA) by the alkylating agent MNNG. Blood 2000; 96: 1415–1424.
-
(2000)
Blood
, vol.96
, pp. 1415-1424
-
-
Parra, M.1
Lluis, F.2
Miralles, F.3
Caelles, C.4
Munoz-Canoves, P.5
-
41
-
-
33645906539
-
Curcumin induces stress response, neurite outgrowth and prevent NF-kappaB activation by inhibiting the proteasome function
-
Dikshit P, Goswami A, Mishra A, Chatterjee M, Jana NR. Curcumin induces stress response, neurite outgrowth and prevent NF-kappaB activation by inhibiting the proteasome function. Neurotox Res 2006; 9: 29–37.
-
(2006)
Neurotox Res
, vol.9
, pp. 29-37
-
-
Dikshit, P.1
Goswami, A.2
Mishra, A.3
Chatterjee, M.4
Jana, N.R.5
-
42
-
-
33644891351
-
Curcumin enhances the polyglutamine-expanded truncated N-terminal huntingtin-induced cell death by promoting proteasomal malfunction
-
Dikshit P, Goswami A, Mishra A, Nukina N, Jana NR. Curcumin enhances the polyglutamine-expanded truncated N-terminal huntingtin-induced cell death by promoting proteasomal malfunction. Biochem Biophys Res Commun 2006; 342: 1323–1328.
-
(2006)
Biochem Biophys Res Commun
, vol.342
, pp. 1323-1328
-
-
Dikshit, P.1
Goswami, A.2
Mishra, A.3
Nukina, N.4
Jana, N.R.5
-
43
-
-
1642564603
-
Inhibition of proteasomal function by curcumin induces apoptosis through mitochondrial pathway
-
Jana NR, Dikshit P, Goswami A, Nukina N. Inhibition of proteasomal function by curcumin induces apoptosis through mitochondrial pathway. J Biol Chem 2004; 279: 11680–11685.
-
(2004)
J Biol Chem
, vol.279
, pp. 11680-11685
-
-
Jana, N.R.1
Dikshit, P.2
Goswami, A.3
Nukina, N.4
-
44
-
-
9144264926
-
Induction of proteasome expression in skeletal muscle is attenuated by inhibitors of NF-kappaB activation
-
Wyke SM, Russell ST, Tisdale MJ. Induction of proteasome expression in skeletal muscle is attenuated by inhibitors of NF-kappaB activation. Br J Cancer 2004; 91: 1742–1750.
-
(2004)
Br J Cancer
, vol.91
, pp. 1742-1750
-
-
Wyke, S.M.1
Russell, S.T.2
Tisdale, M.J.3
-
45
-
-
0028867742
-
Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane) [corrected]
-
Singh S, Aggarwal BB. Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane) [corrected]. J Biol Chem 1995; 270: 24995–25000.
-
(1995)
J Biol Chem
, vol.270
, pp. 24995-25000
-
-
Singh, S.1
Aggarwal, B.B.2
-
46
-
-
0032520716
-
Curcumin (diferuloylmethane) inhibition of tumor necrosis factor (TNF)-mediated adhesion of monocytes to endothelial cells by suppression of cell surface expression of adhesion mole-cules and of nuclear factor-kappaB activation
-
Kumar A, Dhawan S, Hardegen NJ, Aggarwal BB. Curcumin (diferuloylmethane) inhibition of tumor necrosis factor (TNF)-mediated adhesion of monocytes to endothelial cells by suppression of cell surface expression of adhesion mole-cules and of nuclear factor-kappaB activation. Biochem Pharmacol 1998; 55: 775–783.
-
(1998)
Biochem Pharmacol
, vol.55
, pp. 775-783
-
-
Kumar, A.1
Dhawan, S.2
Hardegen, N.J.3
Aggarwal, B.B.4
-
47
-
-
0032743140
-
Curcumin causes the growth arrest and apoptosis of B cell lymphoma by downregulation of egr-1, c-myc, bcl-XL, NF-kappa B, and p53
-
Han SS, Chung ST, Robertson DA, Ranjan D, Bondada S. Curcumin causes the growth arrest and apoptosis of B cell lymphoma by downregulation of egr-1, c-myc, bcl-XL, NF-kappa B, and p53. Clin Immunol 1999; 93: 152–161.
-
(1999)
Clin Immunol
, vol.93
, pp. 152-161
-
-
Han, S.S.1
Chung, S.T.2
Robertson, D.A.3
Ranjan, D.4
Bondada, S.5
-
48
-
-
0033568674
-
Curcumin blocks cytokine-mediated NF-kappa B activation and proinflammatory gene expression by inhibiting inhibitory factor I-kappa B kinase activity
-
Jobin C, Bradham CA, Russo MP, Juma B, Narula AS, Brenner DA et al. Curcumin blocks cytokine-mediated NF-kappa B activation and proinflammatory gene expression by inhibiting inhibitory factor I-kappa B kinase activity. J Immunol 1999; 163: 3474–3483.
-
(1999)
J Immunol
, vol.163
, pp. 3474-3483
-
-
Jobin, C.1
Bradham, C.A.2
Russo, M.P.3
Juma, B.4
Narula, A.S.5
Brenner, D.A.6
-
49
-
-
0032833681
-
Systemic administration of the NF-kappaB inhibitor curcumin stimulates muscle regeneration after traumatic injury
-
Thaloor D, Miller KJ, Gephart J, Mitchell PO, Pavlath GK. Systemic administration of the NF-kappaB inhibitor curcumin stimulates muscle regeneration after traumatic injury. Am J Physiol 1999; 277: C320–C329.
-
(1999)
Am J Physiol
, vol.277
, pp. C320-C329
-
-
Thaloor, D.1
Miller, K.J.2
Gephart, J.3
Mitchell, P.O.4
Pavlath, G.K.5
-
50
-
-
4444294803
-
Curcumin sensitizes prostate cancer cells to tumor necrosis factor-related apoptosis-inducing ligand/ Apo2L by inhibiting nuclear factor-kappaB through suppression of IkappaBalpha phosphorylation
-
Deeb D, Jiang H, Gao X, Hafner MS, Wong H, Divine G et al. Curcumin sensitizes prostate cancer cells to tumor necrosis factor-related apoptosis-inducing ligand/ Apo2L by inhibiting nuclear factor-kappaB through suppression of IkappaBalpha phosphorylation. Mol Cancer Ther 2004; 3: 803–812.
-
(2004)
Mol Cancer Ther
, vol.3
, pp. 803-812
-
-
Deeb, D.1
Jiang, H.2
Gao, X.3
Hafner, M.S.4
Wong, H.5
Divine, G.6
-
51
-
-
3042788374
-
Inhibition of nuclear factor-kappaB and nitric oxide by curcumin induces G2/M cell cycle arrest and apoptosis in human melanoma cells
-
Zheng M, Ekmekcioglu S, Walch ET, Tang CH, Grimm EA. Inhibition of nuclear factor-kappaB and nitric oxide by curcumin induces G2/M cell cycle arrest and apoptosis in human melanoma cells. Melanoma Res 2004; 14: 165–171.
-
(2004)
Melanoma Res
, vol.14
, pp. 165-171
-
-
Zheng, M.1
Ekmekcioglu, S.2
Walch, E.T.3
Tang, C.H.4
Grimm, E.A.5
-
52
-
-
0042377546
-
Mediators of interleukin-1 beta action Na(+)-K(+) ATPase in Caco-2 cells
-
Al-Sadi RM, Kreydiyyeh SI. Mediators of interleukin-1 beta action Na(+)-K(+) ATPase in Caco-2 cells. Eur Cytokine Netw 2003; 14: 83–90.
-
(2003)
Eur Cytokine Netw
, vol.14
, pp. 83-90
-
-
Al-Sadi, R.M.1
Kreydiyyeh, S.I.2
-
53
-
-
18944391961
-
CSN5/Jab1 is involved in ligand-dependent degradation of estrogen receptor {alpha} by the proteasome
-
Callige M, Kieffer I, Richard-Foy H. CSN5/Jab1 is involved in ligand-dependent degradation of estrogen receptor {alpha} by the proteasome. Mol Cell Biol 2005; 25: 4349–4358.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 4349-4358
-
-
Callige, M.1
Kieffer, I.2
Richard-Foy, H.3
-
54
-
-
28644439093
-
Transcriptional regulation of cyclooxygenase-2 in response to proteasome inhibitors involves reactive oxygen species-mediated signaling pathway and recruitment of CCAAT/enhancer-binding protein delta and CREB-binding protein
-
Chen JJ, Huang WC, Chen CC. Transcriptional regulation of cyclooxygenase-2 in response to proteasome inhibitors involves reactive oxygen species-mediated signaling pathway and recruitment of CCAAT/enhancer-binding protein delta and CREB-binding protein. Mol Biol Cell 2005; 16: 5579–5591.
-
(2005)
Mol Biol Cell
, vol.16
, pp. 5579-5591
-
-
Chen, J.J.1
Huang, W.C.2
Chen, C.C.3
-
55
-
-
33745675537
-
Ubiquitin-proteasome pathway function is required for lens cell proliferation and differentiation
-
Guo W, Shang F, Liu Q, Urim L, Zhang M, Taylor A. Ubiquitin-proteasome pathway function is required for lens cell proliferation and differentiation. Invest Ophthal-mol Vis Sci 2006; 47: 2569–2575.
-
(2006)
Invest Ophthal-Mol Vis Sci
, vol.47
, pp. 2569-2575
-
-
Guo, W.1
Shang, F.2
Liu, Q.3
Urim, L.4
Zhang, M.5
Taylor, A.6
-
56
-
-
0037811204
-
Induction of matrix metalloproteinase-13 gene expression by TNF-alpha is mediated by MAP kinases, AP-1, and NF-kappaB transcription factors in articular chondrocytes
-
Liacini A, Sylvester J, Li WQ, Huang W, Dehnade F, Ahmad M et al. Induction of matrix metalloproteinase-13 gene expression by TNF-alpha is mediated by MAP kinases, AP-1, and NF-kappaB transcription factors in articular chondrocytes. Exp Cell Res 2003; 288: 208–217.
-
(2003)
Exp Cell Res
, vol.288
, pp. 208-217
-
-
Liacini, A.1
Sylvester, J.2
Li, W.Q.3
Huang, W.4
Dehnade, F.5
Ahmad, M.6
-
57
-
-
33846855369
-
Tissue-specific regulation of ubiquitin (UbC) transcription by glucocorticoids: In vivo and in vitro analyses
-
Marinovic AC, Zheng B, Mitch WE, Price SR. Tissue-specific regulation of ubiquitin (UbC) transcription by glucocorticoids: in vivo and in vitro analyses. Am J Physiol Renal Physiol 2006; 292: F660–F666.
-
(2006)
Am J Physiol Renal Physiol
, vol.292
, pp. F660-F666
-
-
Marinovic, A.C.1
Zheng, B.2
Mitch, W.E.3
Price, S.R.4
-
58
-
-
0033547876
-
NF-kappaB activation is a critical regulator of human granulocyte apoptosis in vitro
-
Ward C, Chilvers ER, Lawson MF, Pryde JG, Fujihara S, Farrow SN et al. NF-kappaB activation is a critical regulator of human granulocyte apoptosis in vitro. J Biol Chem 1999; 274: 4309–4318.
-
(1999)
J Biol Chem
, vol.274
, pp. 4309-4318
-
-
Ward, C.1
Chilvers, E.R.2
Lawson, M.F.3
Pryde, J.G.4
Fujihara, S.5
Farrow, S.N.6
-
59
-
-
23844516979
-
Proteasome inhibition by lactacystin in primary neuronal cells induces both potentially neuroprotective and pro-apoptotic transcriptional responses: A microarray analysis
-
Yew EH, Cheung NS, Choy MS, Qi RZ, Lee AY, Peng ZF et al. Proteasome inhibition by lactacystin in primary neuronal cells induces both potentially neuroprotective and pro-apoptotic transcriptional responses: a microarray analysis. J Neurochem 2005; 94: 943–956.
-
(2005)
J Neurochem
, vol.94
, pp. 943-956
-
-
Yew, E.H.1
Cheung, N.S.2
Choy, M.S.3
Qi, R.Z.4
Lee, A.Y.5
Peng, Z.F.6
-
60
-
-
24944535336
-
Proteasome inhibition elicits a biphasic effect on neuronal apoptosis via differential regulation of pro-survival and pro-apoptotic transcription factors
-
Butts BD, Hudson HR, Linseman DA, Le SS, Ryan KR, Bouchard RJ et al. Proteasome inhibition elicits a biphasic effect on neuronal apoptosis via differential regulation of pro-survival and pro-apoptotic transcription factors. Mol Cell Neurosci 2005; 30: 279–289.
-
(2005)
Mol Cell Neurosci
, vol.30
, pp. 279-289
-
-
Butts, B.D.1
Hudson, H.R.2
Linseman, D.A.3
Le, S.S.4
Ryan, K.R.5
Bouchard, R.J.6
-
61
-
-
18144363161
-
Proteasome inhibition alters glucose-stimulated (pro)insulin secretion and turnover in pancreatic {beta}-cells
-
Kitiphongspattana K, Mathews CE, Leiter EH, Gaskins HR. Proteasome inhibition alters glucose-stimulated (pro)insulin secretion and turnover in pancreatic {beta}-cells. J Biol Chem 2005; 280: 15727–15734.
-
(2005)
J Biol Chem
, vol.280
, pp. 15727-15734
-
-
Kitiphongspattana, K.1
Mathews, C.E.2
Leiter, E.H.3
Gaskins, H.R.4
-
62
-
-
33749243499
-
Proteasome inhibition induces both pro-and anti-cell death pathways in prostate cancer cells
-
Yang W, Monroe J, Zhang Y, George D, Bremer E, Li H. Proteasome inhibition induces both pro-and anti-cell death pathways in prostate cancer cells. Cancer Lett 2006; 243: 217–227.
-
(2006)
Cancer Lett
, vol.243
, pp. 217-227
-
-
Yang, W.1
Monroe, J.2
Zhang, Y.3
George, D.4
Bremer, E.5
Li, H.6
-
63
-
-
33646406554
-
Celastrol, a triterpene extracted from the Chinese 'Thunder of God Vine,' is a potent proteasome inhibitor and suppresses human prostate cancer growth in nude mice
-
Yang H, Chen D, Cui QC, Yuan X, Dou QP. Celastrol, a triterpene extracted from the Chinese 'Thunder of God Vine,' is a potent proteasome inhibitor and suppresses human prostate cancer growth in nude mice. Cancer Res 2006; 66: 4758–4765.
-
(2006)
Cancer Res
, vol.66
, pp. 4758-4765
-
-
Yang, H.1
Chen, D.2
Cui, Q.C.3
Yuan, X.4
Dou, Q.P.5
-
64
-
-
0038819051
-
Selective inhibitors of the osteoblast proteasome stimulate bone formation in vivo and in vitro
-
Garrett IR, Chen D, Gutierrez G, Zhao M, Escobedo A, Rossini G et al. Selective inhibitors of the osteoblast proteasome stimulate bone formation in vivo and in vitro. J Clin Invest 2003; 111: 1771–1782.
-
(2003)
J Clin Invest
, vol.111
, pp. 1771-1782
-
-
Garrett, I.R.1
Chen, D.2
Gutierrez, G.3
Zhao, M.4
Escobedo, A.5
Rossini, G.6
-
65
-
-
13344259300
-
Evidence that the diabetes gene encodes the leptin receptor: Identification of a mutation in the leptin receptor gene in db/db mice
-
Chen H, Charlat O, Tartaglia LA, Woolf EA, Weng X, Ellis SJ et al. Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice. Cell 1996; 84: 491–495.
-
(1996)
Cell
, vol.84
, pp. 491-495
-
-
Chen, H.1
Charlat, O.2
Tartaglia, L.A.3
Woolf, E.A.4
Weng, X.5
Ellis, S.J.6
-
66
-
-
0037677695
-
Increased islet volume but unchanged islet number in ob/ob mice
-
Bock T, Pakkenberg B, Buschard K. Increased islet volume but unchanged islet number in ob/ob mice. Diabetes 2003; 52: 1716–1722.
-
(2003)
Diabetes
, vol.52
, pp. 1716-1722
-
-
Bock, T.1
Pakkenberg, B.2
Buschard, K.3
-
67
-
-
78650733125
-
Natural proteasome inhibitor celastrol suppresses androgen-independent prostate cancer progression by modulating apoptotic proteins and NF-kappaB
-
Dai Y, Desano J, Tang W, Meng X, Meng Y, Burstein E et al. Natural proteasome inhibitor celastrol suppresses androgen-independent prostate cancer progression by modulating apoptotic proteins and NF-kappaB. PLoS One 2010; 5: e14153.
-
(2010)
Plos One
, vol.5
-
-
Dai, Y.1
Desano, J.2
Tang, W.3
Meng, X.4
Meng, Y.5
Burstein, E.6
-
68
-
-
84857822899
-
Peptidomic analysis of HEK293T cells: Effect of the proteasome inhibitor epoxomicin on intracellular peptides
-
Fricker LD, Gelman JS, Castro LM, Gozzo FC, Ferro ES. Peptidomic analysis of HEK293T cells: effect of the proteasome inhibitor epoxomicin on intracellular peptides. J Proteome Res 2012; 11: 1981–1990.
-
(2012)
J Proteome Res
, vol.11
, pp. 1981-1990
-
-
Fricker, L.D.1
Gelman, J.S.2
Castro, L.M.3
Gozzo, F.C.4
Ferro, E.S.5
-
69
-
-
84860488011
-
JNK3 maintains expression of the insulin receptor substrate 2 (IRS2) in insulin-secreting cells: Functional consequences for insulin signaling
-
Abdelli S, Bonny C. JNK3 maintains expression of the insulin receptor substrate 2 (IRS2) in insulin-secreting cells: functional consequences for insulin signaling. PLoS One 2012; 7: e35997.
-
(2012)
Plos One
, vol.7
-
-
Abdelli, S.1
Bonny, C.2
-
70
-
-
33645217126
-
Selective deletion of Pten in pancreatic beta cells leads to increased islet mass and resistance to STZ-induced diabetes
-
Stiles BL, Kuralwalla-Martinez C, Guo W, Gregorian C, Wang Y, Tian J et al. Selective deletion of Pten in pancreatic beta cells leads to increased islet mass and resistance to STZ-induced diabetes. Mol Cell Biol 2006; 26: 2772–2781.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 2772-2781
-
-
Stiles, B.L.1
Kuralwalla-Martinez, C.2
Guo, W.3
Gregorian, C.4
Wang, Y.5
Tian, J.6
-
71
-
-
33747375615
-
Islet neogenesis associated protein (INGAP) modulates gene expression in cultured neonatal rat islets
-
Barbosa H, Bordin S, Stoppiglia L, Silva K, Borelli M, Del Zotto H et al. Islet neogenesis associated protein (INGAP) modulates gene expression in cultured neonatal rat islets. Regul Pept 2006; 136: 78–84.
-
(2006)
Regul Pept
, vol.136
, pp. 78-84
-
-
Barbosa, H.1
Bordin, S.2
Stoppiglia, L.3
Silva, K.4
Borelli, M.5
Del Zotto, H.6
-
72
-
-
18544367201
-
NF-kappa B as a therapeutic target in multiple myeloma
-
Hideshima T, Chauhan D, Richardson P, Mitsiades C, Mitsiades N, Hayashi T et al. NF-kappa B as a therapeutic target in multiple myeloma. J Biol Chem 2002; 277: 16639–16647.
-
(2002)
J Biol Chem
, vol.277
, pp. 16639-16647
-
-
Hideshima, T.1
Chauhan, D.2
Richardson, P.3
Mitsiades, C.4
Mitsiades, N.5
Hayashi, T.6
-
73
-
-
33645299329
-
'Anti-inflammatory' drugs and their effects on type 2 diabetes
-
Deans KA, Sattar N. 'Anti-inflammatory' drugs and their effects on type 2 diabetes. Diabetes Technol Ther 2006; 8: 18–27.
-
(2006)
Diabetes Technol Ther
, vol.8
, pp. 18-27
-
-
Deans, K.A.1
Sattar, N.2
-
74
-
-
31544441352
-
Inflammation and the etiology of type 2 diabetes
-
Sjoholm A, Nystrom T. Inflammation and the etiology of type 2 diabetes. Diabetes Metab Res Rev 2006; 22: 4–10.
-
(2006)
Diabetes Metab Res Rev
, vol.22
, pp. 4-10
-
-
Sjoholm, A.1
Nystrom, T.2
-
75
-
-
0036099857
-
Mechanism by which high-dose aspirin improves glucose metabolism in type 2 diabetes
-
Hundal RS, Petersen KF, Mayerson AB, Randhawa PS, Inzucchi S, Shoelson SE et al. Mechanism by which high-dose aspirin improves glucose metabolism in type 2 diabetes. J Clin Invest 2002; 109: 1321–1326.
-
(2002)
J Clin Invest
, vol.109
, pp. 1321-1326
-
-
Hundal, R.S.1
Petersen, K.F.2
Mayerson, A.B.3
Randhawa, P.S.4
Inzucchi, S.5
Shoelson, S.E.6
-
76
-
-
33645501804
-
Adiponectin—a key adipokine in the metabolic syndrome
-
Whitehead JP, Richards AA, Hickman IJ, Macdonald GA, Prins JB. Adiponectin—a key adipokine in the metabolic syndrome. Diabetes Obes Metab 2006; 8: 264–280.
-
(2006)
Diabetes Obes Metab
, vol.8
, pp. 264-280
-
-
Whitehead, J.P.1
Richards, A.A.2
Hickman, I.J.3
Macdonald, G.A.4
Prins, J.B.5
-
77
-
-
29144461456
-
Thiazolidinediones: Pleiotropic drugs with potent anti-inflam-matory properties for tissue protection
-
Buckingham RE. Thiazolidinediones: pleiotropic drugs with potent anti-inflam-matory properties for tissue protection. Hepatol Res 2005; 33: 167–170.
-
(2005)
Hepatol Res
, vol.33
, pp. 167-170
-
-
Buckingham, R.E.1
-
78
-
-
23944438407
-
The effect of low-dose atorvastatin on circulating monocyte chemoattractant protein-1 in patients with type 2 diabetes complicated by hyperlipidemia
-
Takebayashi K, Matsumoto S, Wakabayashi S, Inukai Y, Matsutomo R, Aso Y et al. The effect of low-dose atorvastatin on circulating monocyte chemoattractant protein-1 in patients with type 2 diabetes complicated by hyperlipidemia. Metabolism 2005; 54: 1225–1229.
-
(2005)
Metabolism
, vol.54
, pp. 1225-1229
-
-
Takebayashi, K.1
Matsumoto, S.2
Wakabayashi, S.3
Inukai, Y.4
Matsutomo, R.5
Aso, Y.6
-
79
-
-
12144279068
-
Nuclear factor-{kappa}B activity in {beta}-cells is required for glucose-stimulated insulin secretion
-
Norlin S, Ahlgren U, Edlund H. Nuclear factor-{kappa}B activity in {beta}-cells is required for glucose-stimulated insulin secretion. Diabetes 2005; 54: 125–132.
-
(2005)
Diabetes
, vol.54
, pp. 125-132
-
-
Norlin, S.1
Ahlgren, U.2
Edlund, H.3
-
80
-
-
0037441994
-
NF-kappa B hyperactivation has differential effects on the APC function of nonobese diabetic mouse macrophages
-
Sen P, Bhattacharyya S, Wallet M, Wong CP, Poligone B, Sen M et al. NF-kappa B hyperactivation has differential effects on the APC function of nonobese diabetic mouse macrophages. J Immunol 2003; 170: 1770–1780.
-
(2003)
J Immunol
, vol.170
, pp. 1770-1780
-
-
Sen, P.1
Bhattacharyya, S.2
Wallet, M.3
Wong, C.P.4
Poligone, B.5
Sen, M.6
-
81
-
-
21044453408
-
Disruption of the Jnk2 (Mapk9) gene reduces destructive insulitis and diabetes in a mouse model of type I diabetes
-
Jaeschke A, Rincon M, Doran B, Reilly J, Neuberg D, Greiner DL et al. Disruption of the Jnk2 (Mapk9) gene reduces destructive insulitis and diabetes in a mouse model of type I diabetes. Proc Natl Acad Sci USA 2005; 102: 6931–6935.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 6931-6935
-
-
Jaeschke, A.1
Rincon, M.2
Doran, B.3
Reilly, J.4
Neuberg, D.5
Greiner, D.L.6
-
82
-
-
1842582779
-
Oxidative stress is a mediator of glucose toxicity in insulin-secreting pancreatic islet cell lines
-
Wu L, Nicholson W, Knobel SM, Steffner RJ, May JM, Piston DW et al. Oxidative stress is a mediator of glucose toxicity in insulin-secreting pancreatic islet cell lines. J Biol Chem 2004; 279: 12126–12134.
-
(2004)
J Biol Chem
, vol.279
, pp. 12126-12134
-
-
Wu, L.1
Nicholson, W.2
Knobel, S.M.3
Steffner, R.J.4
May, J.M.5
Piston, D.W.6
-
83
-
-
84871971567
-
Therapeutic roles of curcumin: Lessons learned from clinical trials
-
Gupta SC, Patchra S, Aggarwal BB, Therapeutic roles of curcumin: lessons learned from clinical trials. AAPS 2013; 15: 195–218.
-
(2013)
AAPS
, vol.15
, pp. 195-218
-
-
Gupta, S.C.1
Patchra, S.2
Aggarwal, B.B.3
|