메뉴 건너뛰기




Volumn 21, Issue 9, 2016, Pages 1504-1511

In vitro and ex vivo models of multiple sclerosis

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; BIOLOGICAL MODEL; BRAIN; CELL CULTURE; HUMAN; MULTIPLE SCLEROSIS; OLIGODENDROGLIA; PRECLINICAL STUDY; PROCEDURES; TISSUE CULTURE TECHNIQUE;

EID: 84988410239     PISSN: 13596446     EISSN: 18785832     Source Type: Journal    
DOI: 10.1016/j.drudis.2016.05.018     Document Type: Review
Times cited : (18)

References (54)
  • 1
    • 0026436606 scopus 로고
    • Autocrine inhibition of mitotic activity in cultured oligodendrocyte-type-2 astrocyte (O-2A) precursor cells
    • 1 Louis, J.C., et al. Autocrine inhibition of mitotic activity in cultured oligodendrocyte-type-2 astrocyte (O-2A) precursor cells. Glia 6 (1992), 30–38.
    • (1992) Glia , vol.6 , pp. 30-38
    • Louis, J.C.1
  • 2
    • 84883469861 scopus 로고    scopus 로고
    • Purification and culture of oligodendrocyte lineage cells
    • 2 Dugas, J.C., Emery, B., Purification and culture of oligodendrocyte lineage cells. Cold Spring Harb. Protoc. 2013 (2013), 810–814.
    • (2013) Cold Spring Harb. Protoc. , vol.2013 , pp. 810-814
    • Dugas, J.C.1    Emery, B.2
  • 3
    • 77950146306 scopus 로고    scopus 로고
    • Differing in vitro survival dependency of mouse and rat NG2+ oligodendroglial progenitor cells
    • 3 Horiuchi, M., et al. Differing in vitro survival dependency of mouse and rat NG2+ oligodendroglial progenitor cells. J. Neurosci. Res. 88 (2010), 957–970.
    • (2010) J. Neurosci. Res. , vol.88 , pp. 957-970
    • Horiuchi, M.1
  • 4
    • 84942293158 scopus 로고    scopus 로고
    • CNS myelin sheath lengths are an intrinsic property of oligodendrocytes
    • 4 Bechler, M.E., et al. CNS myelin sheath lengths are an intrinsic property of oligodendrocytes. Curr. Biol. 25 (2015), 2411–2416.
    • (2015) Curr. Biol. , vol.25 , pp. 2411-2416
    • Bechler, M.E.1
  • 5
    • 0028872351 scopus 로고
    • The effect of oncogenes on the growth and differentiation of oligodendrocyte type 2 astrocyte progenitor cells
    • 5 Barnett, S.C., Crouch, D.H., The effect of oncogenes on the growth and differentiation of oligodendrocyte type 2 astrocyte progenitor cells. Cell Growth Differ. 6 (1995), 69–80.
    • (1995) Cell Growth Differ. , vol.6 , pp. 69-80
    • Barnett, S.C.1    Crouch, D.H.2
  • 6
    • 0037595350 scopus 로고    scopus 로고
    • Characterization of three human oligodendroglial cell lines as a model to study oligodendrocyte injury: morphology and oligodendrocyte-specific gene expression
    • 6 Buntinx, M., et al. Characterization of three human oligodendroglial cell lines as a model to study oligodendrocyte injury: morphology and oligodendrocyte-specific gene expression. J. Neurocytol. 32 (2003), 25–38.
    • (2003) J. Neurocytol. , vol.32 , pp. 25-38
    • Buntinx, M.1
  • 7
    • 78651279257 scopus 로고    scopus 로고
    • Glial cell lines: an overview
    • 7 De Vries, G.H., Boullerne, A.I., Glial cell lines: an overview. Neurochem. Res. 35 (2010), 1978–2000.
    • (2010) Neurochem. Res. , vol.35 , pp. 1978-2000
    • De Vries, G.H.1    Boullerne, A.I.2
  • 8
    • 84902532010 scopus 로고    scopus 로고
    • Temporal oligodendrocyte lineage progression: in vitro models of proliferation, differentiation and myelination
    • 8 Barateiro, A., Fernandes, A., Temporal oligodendrocyte lineage progression: in vitro models of proliferation, differentiation and myelination. Biochim. Biophys. Acta 1843 (2014), 1917–1929.
    • (2014) Biochim. Biophys. Acta , vol.1843 , pp. 1917-1929
    • Barateiro, A.1    Fernandes, A.2
  • 9
    • 84907152853 scopus 로고    scopus 로고
    • Finding degrees of separation: experimental approaches for astroglial and oligodendroglial cell isolation and genetic targeting
    • 9 Chew, L.J., et al. Finding degrees of separation: experimental approaches for astroglial and oligodendroglial cell isolation and genetic targeting. J. Neurosci. Methods 236 (2014), 125–147.
    • (2014) J. Neurosci. Methods , vol.236 , pp. 125-147
    • Chew, L.J.1
  • 10
    • 84949191914 scopus 로고    scopus 로고
    • Isolation and long-term expansion of functional, myelinating oligodendrocyte progenitor cells from neonatal rat brain
    • 2D.17.1-15
    • 10 Zhu, B., et al. Isolation and long-term expansion of functional, myelinating oligodendrocyte progenitor cells from neonatal rat brain. Curr. Protoc. Stem Cell Biol., 31, 2014 2D.17.1-15.
    • (2014) Curr. Protoc. Stem Cell Biol. , vol.31
    • Zhu, B.1
  • 11
    • 84863696278 scopus 로고    scopus 로고
    • Isolation of cortical mouse oligodendrocyte precursor cells
    • 11 Dincman, T.A., et al. Isolation of cortical mouse oligodendrocyte precursor cells. J. Neurosci. Methods 209 (2012), 219–226.
    • (2012) J. Neurosci. Methods , vol.209 , pp. 219-226
    • Dincman, T.A.1
  • 12
    • 73949130191 scopus 로고    scopus 로고
    • Differentiation of human oligodendrocytes from pluripotent stem cells
    • 12 Hu, B.Y., et al. Differentiation of human oligodendrocytes from pluripotent stem cells. Nat. Protoc. 4 (2009), 1614–1622.
    • (2009) Nat. Protoc. , vol.4 , pp. 1614-1622
    • Hu, B.Y.1
  • 13
    • 84924219729 scopus 로고    scopus 로고
    • Efficient generation of myelinating oligodendrocytes from primary progressive multiple sclerosis patients by induced pluripotent stem cells
    • 13 Douvaras, P., et al. Efficient generation of myelinating oligodendrocytes from primary progressive multiple sclerosis patients by induced pluripotent stem cells. Stem Cell Rep. 3 (2014), 250–259.
    • (2014) Stem Cell Rep. , vol.3 , pp. 250-259
    • Douvaras, P.1
  • 14
    • 84890949264 scopus 로고    scopus 로고
    • Human umbilical cord Wharton's jelly-derived oligodendrocyte precursor-like cells for axon and myelin sheath regeneration
    • 14 Chen, H., et al. Human umbilical cord Wharton's jelly-derived oligodendrocyte precursor-like cells for axon and myelin sheath regeneration. Neural Regen. Res. 8 (2013), 890–899.
    • (2013) Neural Regen. Res. , vol.8 , pp. 890-899
    • Chen, H.1
  • 15
    • 84910047126 scopus 로고    scopus 로고
    • Differentiation of human umbilical cord matrix mesenchymal stem cells into neural-like progenitor cells and maturation into an oligodendroglial-like lineage
    • 15 Leite, C., et al. Differentiation of human umbilical cord matrix mesenchymal stem cells into neural-like progenitor cells and maturation into an oligodendroglial-like lineage. PLoS ONE, 9, 2014, e111059.
    • (2014) PLoS ONE , vol.9 , pp. e111059
    • Leite, C.1
  • 16
    • 84855465359 scopus 로고    scopus 로고
    • Neural differentiation of patient specific iPS cells as a novel approach to study the pathophysiology of multiple sclerosis
    • 16 Song, B., et al. Neural differentiation of patient specific iPS cells as a novel approach to study the pathophysiology of multiple sclerosis. Stem Cell Res. 8 (2012), 259–273.
    • (2012) Stem Cell Res. , vol.8 , pp. 259-273
    • Song, B.1
  • 17
    • 46449094276 scopus 로고    scopus 로고
    • Dissecting direct reprogramming through integrative genomic analysis
    • 17 Mikkelsen, T.S., et al. Dissecting direct reprogramming through integrative genomic analysis. Nature 454 (2008), 49–55.
    • (2008) Nature , vol.454 , pp. 49-55
    • Mikkelsen, T.S.1
  • 18
    • 84954322927 scopus 로고    scopus 로고
    • Multiple sclerosis: getting personal with induced pluripotent stem cells
    • 18 Di Ruscio, A., et al. Multiple sclerosis: getting personal with induced pluripotent stem cells. Cell Death Dis., 6, 2015, e1806.
    • (2015) Cell Death Dis. , vol.6 , pp. e1806
    • Di Ruscio, A.1
  • 19
    • 0027529578 scopus 로고
    • Time course of synaptic development in hippocampal organotypic cultures
    • 19 Muller, D., et al. Time course of synaptic development in hippocampal organotypic cultures. Brain Res. Dev. Brain Res. 71 (1993), 93–100.
    • (1993) Brain Res. Dev. Brain Res. , vol.71 , pp. 93-100
    • Muller, D.1
  • 20
    • 0027436301 scopus 로고
    • Lesion-induced neurite sprouting and synapse formation in hippocampal organotypic cultures
    • 20 Stoppini, L., et al. Lesion-induced neurite sprouting and synapse formation in hippocampal organotypic cultures. Neuroscience 57 (1993), 985–994.
    • (1993) Neuroscience , vol.57 , pp. 985-994
    • Stoppini, L.1
  • 21
    • 34347253602 scopus 로고    scopus 로고
    • Preparation of organotypic hippocampal slice cultures for long-term live imaging
    • 21 Gogolla, N., et al. Preparation of organotypic hippocampal slice cultures for long-term live imaging. Nat. Protoc. 1 (2006), 1165–1171.
    • (2006) Nat. Protoc. , vol.1 , pp. 1165-1171
    • Gogolla, N.1
  • 22
    • 62049083050 scopus 로고    scopus 로고
    • Live imaging of remyelination after antibody-mediated demyelination in an ex-vivo model for immune mediated CNS damage
    • 22 Harrer, M.D., et al. Live imaging of remyelination after antibody-mediated demyelination in an ex-vivo model for immune mediated CNS damage. Exp. Neurol. 216 (2009), 431–438.
    • (2009) Exp. Neurol. , vol.216 , pp. 431-438
    • Harrer, M.D.1
  • 23
    • 4744349978 scopus 로고    scopus 로고
    • Lysolecithin induces demyelination in vitro in a cerebellar slice culture system
    • 23 Birgbauer, E., et al. Lysolecithin induces demyelination in vitro in a cerebellar slice culture system. J. Neurosci. Res. 78 (2004), 157–166.
    • (2004) J. Neurosci. Res. , vol.78 , pp. 157-166
    • Birgbauer, E.1
  • 24
    • 84902603087 scopus 로고    scopus 로고
    • Fingolimod attenuates splenocyte-induced demyelination in cerebellar slice cultures
    • 24 Pritchard, A.J., et al. Fingolimod attenuates splenocyte-induced demyelination in cerebellar slice cultures. PLoS ONE, 9, 2014, e99444.
    • (2014) PLoS ONE , vol.9 , pp. e99444
    • Pritchard, A.J.1
  • 25
    • 4243576477 scopus 로고
    • Nouvelles recherches sur le tissu nerveux cultivé in vitro. Morphologie, croissance et relations réciproques des neurones
    • 25 Levi, G.M.H., Nouvelles recherches sur le tissu nerveux cultivé in vitro. Morphologie, croissance et relations réciproques des neurones. Arch. Biol. 52 (1941), 133–278.
    • (1941) Arch. Biol. , vol.52 , pp. 133-278
    • Levi, G.M.H.1
  • 26
    • 79958046634 scopus 로고    scopus 로고
    • Central nervous system remyelination in culture – a tool for multiple sclerosis research
    • 26 Zhang, H., et al. Central nervous system remyelination in culture – a tool for multiple sclerosis research. Exp. Neurol. 230 (2011), 138–148.
    • (2011) Exp. Neurol. , vol.230 , pp. 138-148
    • Zhang, H.1
  • 27
    • 11344261775 scopus 로고    scopus 로고
    • Multiple dorsoventral origins of oligodendrocyte generation in the spinal cord and hindbrain
    • 27 Vallstedt, A., et al. Multiple dorsoventral origins of oligodendrocyte generation in the spinal cord and hindbrain. Neuron 45 (2005), 55–67.
    • (2005) Neuron , vol.45 , pp. 55-67
    • Vallstedt, A.1
  • 28
    • 84883454794 scopus 로고    scopus 로고
    • M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination
    • 28 Miron, V.E., et al. M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination. Nat. Neurosci. 16 (2013), 1211–1218.
    • (2013) Nat. Neurosci. , vol.16 , pp. 1211-1218
    • Miron, V.E.1
  • 29
    • 70349232336 scopus 로고    scopus 로고
    • Collateral bystander damage by myelin-directed CD8+ T cells causes axonal loss
    • 29 Sobottka, B., et al. Collateral bystander damage by myelin-directed CD8+ T cells causes axonal loss. Am. J. Pathol. 175 (2009), 1160–1166.
    • (2009) Am. J. Pathol. , vol.175 , pp. 1160-1166
    • Sobottka, B.1
  • 30
    • 0036549138 scopus 로고    scopus 로고
    • The age-related decrease in CNS remyelination efficiency is attributable to an impairment of both oligodendrocyte progenitor recruitment and differentiation
    • 30 Sim, F.J., et al. The age-related decrease in CNS remyelination efficiency is attributable to an impairment of both oligodendrocyte progenitor recruitment and differentiation. J. Neurosci. 22 (2002), 2451–2459.
    • (2002) J. Neurosci. , vol.22 , pp. 2451-2459
    • Sim, F.J.1
  • 31
    • 50949097403 scopus 로고    scopus 로고
    • In situ activation of antigen-specific CD8+ T cells in the presence of antigen in organotypic brain slices
    • 31 Ling, C., et al. In situ activation of antigen-specific CD8+ T cells in the presence of antigen in organotypic brain slices. J. Immunol. 180 (2008), 8393–8399.
    • (2008) J. Immunol. , vol.180 , pp. 8393-8399
    • Ling, C.1
  • 32
    • 84908364762 scopus 로고    scopus 로고
    • Oligodendrocyte progenitors: adult stem cells of the central nervous system?
    • 32 Crawford, A.H., et al. Oligodendrocyte progenitors: adult stem cells of the central nervous system?. Exp. Neurol. 260 (2014), 50–55.
    • (2014) Exp. Neurol. , vol.260 , pp. 50-55
    • Crawford, A.H.1
  • 33
    • 84951172662 scopus 로고    scopus 로고
    • Retinoid X receptor activation reverses age-related deficiencies in myelin debris phagocytosis and remyelination
    • 33 Natrajan, M.S., et al. Retinoid X receptor activation reverses age-related deficiencies in myelin debris phagocytosis and remyelination. Brain 138 (2015), 3581–3597.
    • (2015) Brain , vol.138 , pp. 3581-3597
    • Natrajan, M.S.1
  • 34
    • 84946097393 scopus 로고    scopus 로고
    • Galactosylsphingosine (psychosine)-induced demyelination is attenuated by sphingosine 1-phosphate signalling
    • 34 O'Sullivan, C., Dev, K.K., Galactosylsphingosine (psychosine)-induced demyelination is attenuated by sphingosine 1-phosphate signalling. J. Cell. Sci. 128 (2015), 3878–3887.
    • (2015) J. Cell. Sci. , vol.128 , pp. 3878-3887
    • O'Sullivan, C.1    Dev, K.K.2
  • 35
    • 35548984947 scopus 로고    scopus 로고
    • The immunomodulator FTY720 has a direct cytoprotective effect in oligodendrocyte progenitors
    • 35 Coelho, R.P., et al. The immunomodulator FTY720 has a direct cytoprotective effect in oligodendrocyte progenitors. J. Pharmacol. Exp. Ther. 323 (2007), 626–635.
    • (2007) J. Pharmacol. Exp. Ther. , vol.323 , pp. 626-635
    • Coelho, R.P.1
  • 36
    • 35348940243 scopus 로고    scopus 로고
    • Functional consequences of S1P receptor modulation in rat oligodendroglial lineage cells
    • 36 Jung, C.G., et al. Functional consequences of S1P receptor modulation in rat oligodendroglial lineage cells. Glia 55 (2007), 1656–1667.
    • (2007) Glia , vol.55 , pp. 1656-1667
    • Jung, C.G.1
  • 37
    • 39049125218 scopus 로고    scopus 로고
    • FTY720 modulates human oligodendrocyte progenitor process extension and survival
    • 37 Miron, V.E., et al. FTY720 modulates human oligodendrocyte progenitor process extension and survival. Ann. Neurol. 63 (2008), 61–71.
    • (2008) Ann. Neurol. , vol.63 , pp. 61-71
    • Miron, V.E.1
  • 38
    • 77957660978 scopus 로고    scopus 로고
    • Design and synthesis of selective and potent orally active S1P5 agonists
    • 38 Mattes, H., et al. Design and synthesis of selective and potent orally active S1P5 agonists. ChemMedChem 5 (2010), 1693–1696.
    • (2010) ChemMedChem , vol.5 , pp. 1693-1696
    • Mattes, H.1
  • 39
    • 84958155181 scopus 로고    scopus 로고
    • The dual S1PR1/S1PR5 drug BAF312 (Siponimod) attenuates demyelination in organotypic slice cultures
    • 39 O'Sullivan, C., et al. The dual S1PR1/S1PR5 drug BAF312 (Siponimod) attenuates demyelination in organotypic slice cultures. J. Neuroinflammation, 13, 2016, 31.
    • (2016) J. Neuroinflammation , vol.13 , pp. 31
    • O'Sullivan, C.1
  • 40
    • 84856219980 scopus 로고    scopus 로고
    • S1P1 receptor subtype inhibits demyelination and regulates chemokine release in cerebellar slice cultures
    • 40 Sheridan, G.K., Dev, K.K., S1P1 receptor subtype inhibits demyelination and regulates chemokine release in cerebellar slice cultures. Glia 60 (2012), 382–392.
    • (2012) Glia , vol.60 , pp. 382-392
    • Sheridan, G.K.1    Dev, K.K.2
  • 41
    • 77953225859 scopus 로고    scopus 로고
    • Fingolimod (FTY720) enhances remyelination following demyelination of organotypic cerebellar slices
    • 41 Miron, V.E., et al. Fingolimod (FTY720) enhances remyelination following demyelination of organotypic cerebellar slices. Am. J. Pathol. 176 (2010), 2682–2694.
    • (2010) Am. J. Pathol. , vol.176 , pp. 2682-2694
    • Miron, V.E.1
  • 42
    • 84906851190 scopus 로고    scopus 로고
    • Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis
    • 42 Mei, F., et al. Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis. Nat. Med. 20 (2014), 954–960.
    • (2014) Nat. Med. , vol.20 , pp. 954-960
    • Mei, F.1
  • 43
    • 84930349658 scopus 로고    scopus 로고
    • Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo
    • 43 Najm, F.J., et al. Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo. Nature 522 (2015), 216–220.
    • (2015) Nature , vol.522 , pp. 216-220
    • Najm, F.J.1
  • 44
    • 45549107414 scopus 로고    scopus 로고
    • Purification of oligodendrocytes and their progenitors using immunomagnetic separation and Percoll gradient centrifugation
    • Chapter 3, Unit 3.12
    • 44 Colello, R.J., Sato-Bigbee, C., Purification of oligodendrocytes and their progenitors using immunomagnetic separation and Percoll gradient centrifugation. Curr. Protoc. Neurosci., 2001 Chapter 3, Unit 3.12.
    • (2001) Curr. Protoc. Neurosci.
    • Colello, R.J.1    Sato-Bigbee, C.2
  • 45
    • 84863643452 scopus 로고    scopus 로고
    • An efficient and economical culture approach for the enrichment of purified oligodendrocyte progenitor cells
    • 45 Niu, J., et al. An efficient and economical culture approach for the enrichment of purified oligodendrocyte progenitor cells. J. Neurosci. Methods 209 (2012), 241–249.
    • (2012) J. Neurosci. Methods , vol.209 , pp. 241-249
    • Niu, J.1
  • 46
    • 0019313317 scopus 로고
    • Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue
    • 46 McCarthy, K.D., de Vellis, J., Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue. J. Cell Biol. 85 (1980), 890–902.
    • (1980) J. Cell Biol. , vol.85 , pp. 890-902
    • McCarthy, K.D.1    de Vellis, J.2
  • 47
    • 0033573222 scopus 로고    scopus 로고
    • Mouse oligospheres: from pre-progenitors to functional oligodendrocytes
    • 47 Vitry, S., et al. Mouse oligospheres: from pre-progenitors to functional oligodendrocytes. J. Neurosci. Res. 58 (1999), 735–751.
    • (1999) J. Neurosci. Res. , vol.58 , pp. 735-751
    • Vitry, S.1
  • 48
    • 84941120442 scopus 로고    scopus 로고
    • Isolation and culture of human oligodendrocyte precursor cells from neurospheres
    • 48 Lu, Y., et al. Isolation and culture of human oligodendrocyte precursor cells from neurospheres. Brain Res. Bull. 118 (2015), 17–24.
    • (2015) Brain Res. Bull. , vol.118 , pp. 17-24
    • Lu, Y.1
  • 49
    • 84937873031 scopus 로고    scopus 로고
    • Generation and isolation of oligodendrocyte progenitor cells from human pluripotent stem cells
    • 49 Douvaras, P., Fossati, V., Generation and isolation of oligodendrocyte progenitor cells from human pluripotent stem cells. Nat. Protoc. 10 (2015), 1143–1154.
    • (2015) Nat. Protoc. , vol.10 , pp. 1143-1154
    • Douvaras, P.1    Fossati, V.2
  • 50
    • 84888128616 scopus 로고    scopus 로고
    • High yields of oligodendrocyte lineage cells from human embryonic stem cells at physiological oxygen tensions for evaluation of translational biology
    • 50 Stacpoole, S.R., et al. High yields of oligodendrocyte lineage cells from human embryonic stem cells at physiological oxygen tensions for evaluation of translational biology. Stem Cell Rep. 1 (2013), 437–450.
    • (2013) Stem Cell Rep. , vol.1 , pp. 437-450
    • Stacpoole, S.R.1
  • 51
    • 84873599764 scopus 로고    scopus 로고
    • Human iPSC-derived oligodendrocyte progenitor cells can myelinate and rescue a mouse model of congenital hypomyelination
    • 51 Human iPSC-derived oligodendrocyte progenitor cells can myelinate and rescue a mouse model of congenital hypomyelination. Cell Stem Cell 12 (2013), 252–264.
    • (2013) Cell Stem Cell , vol.12 , pp. 252-264
  • 52
    • 78149462716 scopus 로고    scopus 로고
    • Developmental genetics of vertebrate glial-cell specification
    • 52 Rowitch, D.H., Kriegstein, A.R., Developmental genetics of vertebrate glial-cell specification. Nature 468:7321 (2010), 214–222.
    • (2010) Nature , vol.468 , Issue.7321 , pp. 214-222
    • Rowitch, D.H.1    Kriegstein, A.R.2
  • 53
    • 84930325732 scopus 로고    scopus 로고
    • Adventures in Wonderland
    • 53 Kucenas, S., Adventures in Wonderland. PLoS Genetics, 11(4), 2015.
    • (2015) PLoS Genetics , vol.11 , Issue.4
    • Kucenas, S.1
  • 54
    • 84877337520 scopus 로고    scopus 로고
    • Transcription factor-mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cells
    • 54 Najm, F.J., et al. Transcription factor-mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cells. Nat Biotechnol. 31:5 (2013), 426–433.
    • (2013) Nat Biotechnol. , vol.31 , Issue.5 , pp. 426-433
    • Najm, F.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.