Central nervous system remyelination in culture - A tool for multiple sclerosis research

Experimental Neurology

Volumn 230, Issue 1, 2011, Pages 138-148

  Zhang, Hui ^a   Jarjour, Andrew A ^a   Boyd, Amanda ^a   Williams, Anna ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Demyelination; Multiple sclerosis; Myelination; Oligodendrocyte; Remyelination

Indexed keywords

MYELIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CONTROLLED STUDY; DEMYELINATION; DISEASE COURSE; DISEASE MODEL; DRUG RESEARCH; EX VIVO STUDY; HIGH THROUGHPUT SCREENING; IN VIVO STUDY; MOUSE; MULTIPLE SCLEROSIS; MYELINATION; NERVE CONDUCTION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REMYELINIZATION; SPINAL CORD; TISSUE CULTURE;

2',3'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASES; ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; ANTIGENS; BROMODEOXYURIDINE; CELL PROLIFERATION; CENTRAL NERVOUS SYSTEM; DEMYELINATING DISEASES; GREEN FLUORESCENT PROTEINS; LYSOPHOSPHATIDYLCHOLINES; MICE; MICE, TRANSGENIC; MODELS, BIOLOGICAL; MYELIN BASIC PROTEINS; MYELIN SHEATH; NEUROFILAMENT PROTEINS; OLIGODENDROGLIA; ORGAN CULTURE TECHNIQUES; PROTEOGLYCANS; RNA, MESSENGER; STEM CELLS;

EID: 79958046634     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2011.04.009     Document Type: Article

References (44)

1. Barkhof F., Bruck W., De Groot C.J., Bergers E., Hulshof S., Geurts J., Polman C.H., van der Valk P. Remyelinated lesions in multiple sclerosis: magnetic resonance image appearance. Arch. Neurol. 2003, 60:1073-1081.
2. Birgbauer E., Rao T.S., Webb M. Lysolecithin induces demyelination in vitro in a cerebellar slice culture system. J. Neurosci. Res. 2004, 78:157-166.
3. Blakemore W.F., Franklin R.J. Remyelination in experimental models of toxin-induced demyelination. Curr. Top. Microbiol. Immunol. 2008, 318:193-212.
4. Bornstein M.B., Appel S.H. Demyelination in cultures of rat cerebellum produced by experimental allergic encephalomyelitic serum. Trans. Am. Neurol. Assoc. 1959, 84:165-166.
5. Bruck W., Bitsch A., Kolenda H., Bruck Y., Stiefel M., Lassmann H. Inflammatory central nervous system demyelination: correlation of magnetic resonance imaging findings with lesion pathology. Ann. Neurol. 1997, 42:783-793.
6. Chan J.R., Watkins T.A., Cosgaya J.M., Zhang C., Chen L., Reichardt L.F., Shooter E.M., Barres B.A. NGF controls axonal receptivity to myelination by Schwann cells or oligodendrocytes. Neuron 2004, 43:183-191.
7. Chen J.T., Kuhlmann T., Jansen G.H., Collins D.L., Atkins H.L., Freedman M.S., O'Connor P.W., Arnold D.L. Voxel-based analysis of the evolution of magnetization transfer ratio to quantify remyelination and demyelination with histopathological validation in a multiple sclerosis lesion. Neuroimage 2007, 36:1152-1158.
8. De Stefano N., Narayanan S., Francis G.S., Arnaoutelis R., Tartaglia M.C., Antel J.P., Matthews P.M., Arnold D.L. Evidence of axonal damage in the early stages of multiple sclerosis and its relevance to disability. Arch. Neurol. 2001, 58:65-70.
9. Dubois-Dalcq M., Williams A., Stadelmann C., Stankoff B., Zalc B., Lubetzki C. From fish to man: understanding endogenous remyelination in central nervous system demyelinating diseases. Brain 2008, 131:1686-1700.
10. Duncan I.D., Brower A., Kondo Y., Curlee J.F., Schultz R.D. Extensive remyelination of the CNS leads to functional recovery. Proc. Natl. Acad. Sci. USA 2009, 106:6832-6836.
11. Dutta R., Trapp B.D. Pathogenesis of axonal and neuronal damage in multiple sclerosis. Neurology 2007, 68:S22-S31. (discussion S43-54).
12. Fisniku L.K., Chard D.T., Jackson J.S., Anderson V.M., Altmann D.R., Miszkiel K.A., Thompson A.J., Miller D.H. Gray matter atrophy is related to long-term disability in multiple sclerosis. Ann. Neurol. 2008, 64:247-254.
13. Franklin R.J., Ffrench-Constant C. Remyelination in the CNS: from biology to therapy. Nat. Rev. Neurosci. 2008, 9:839-855.
14. Furlan R., Cuomo C., Martino G. Animal models of multiple sclerosis. Methods Mol. Biol. 2009, 549:157-173.
15. Ghoumari A.M., Ibanez C., El-Etr M., Leclerc P., Eychenne B., O'Malley B.W., Baulieu E.E., Schumacher M. Progesterone and its metabolites increase myelin basic protein expression in organotypic slice cultures of rat cerebellum. J. Neurochem. 2003, 86:848-859.
16. Goldschmidt T., Antel J., Konig F.B., Bruck W., Kuhlmann T. Remyelination capacity of the MS brain decreases with disease chronicity. Neurology 2009, 72:1914-1921.
17. Haber M., Vautrin S., Fry E.J., Murai K.K. Subtype-specific oligodendrocyte dynamics in organotypic culture. Glia 2009, 57:1000-1013.
18. Hild W. Myelin formation in central nervous system tissue cultures. Verh. Anat. Ges. 1956, 53:315-317.
19. Huang J.K., Jarjour A.A., Nait-Oumesmar B., Kerninon C., Williams A., Krezel W., Kagechika H., Bauer J., Zhao C., Baron-Van Evercooren A., Chambon P., ffrench-Constant C., Franklin R.J.M. Retinoid X receptor gamma signaling accelerates CNS remyelination. Nat. Neurosci. 2011, 14(1):45-53.
20. Irvine K.A., Blakemore W.F. Remyelination protects axons from demyelination-associated axon degeneration. Brain 2008, 131:1464-1477.
21. Latasa M.J., Ituero M., Moran-Gonzalez A., Aranda A., Cosgaya J.M. Retinoic acid regulates myelin formation in the peripheral nervous system. Glia 2010, 58:1451-1464.
22. Levi G., Meyer H. Nouvelles recherches sur le tissu nerveux cultivé in vitro. Morphologie, croissance et relations réciproques des neurones. Arch. Biol. (Paris) 1941, 52:133-278.
23. Lubetzki C., Demerens C., Anglade P., Villarroya H., Frankfurter A., Lee V.M., Zalc B. Even in culture, oligodendrocytes myelinate solely axons. Proc. Natl. Acad. Sci. USA 1993, 90:6820-6824.
24. McCarthy K.D., de Vellis J. Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue. J. Cell Biol. 1980, 85:890-902.
25. Mi S., Miller R.H., Tang W., Lee X., Hu B., Wu W., Zhang Y., Shields C.B., Zhang Y., Miklasz S., Shea D., Mason J., Franklin R.J., Ji B., Shao Z., Chedotal A., Bernard F., Roulois A., Xu J., Jung V., Pepinsky B. Promotion of central nervous system remyelination by induced differentiation of oligodendrocyte precursor cells. Ann. Neurol. 2009, 65:304-315.
26. Miron V.E., Ludwin S.K., Darlington P.J., Jarjour A.A., Soliven B., Kennedy T.E., Antel J.P. Fingolimod (FTY720) enhances remyelination following demyelination of organotypic cerebellar slices. Am. J. Pathol. 2010, 176:2682-2694.
27. Nishimura R.N., Blank N.K., Tiekotter K.L., Cole R., de Vellis J. Myelination of mouse cerebellar explants by rat cultured oligodendrocytes. Brain Res. 1985, 337:159-162.
28. Notterpek L.M., Bullock P.N., Malek-Hedayat S., Fisher R., Rome L.H. Myelination in cerebellar slice cultures: development of a system amenable to biochemical analysis. J. Neurosci. Res. 1993, 36:621-634.
29. Patani R., Balaratnam M., Vora A., Reynolds R. Remyelination can be extensive in multiple sclerosis despite a long disease course. Neuropathol. Appl. Neurobiol. 2007, 33:277-287.
30. Patrikios P., Stadelmann C., Kutzelnigg A., Rauschka H., Schmidbauer M., Laursen H., Sorensen P.S., Bruck W., Lucchinetti C., Lassmann H. Remyelination is extensive in a subset of multiple sclerosis patients. Brain 2006, 129:3165-3172.
31. Penderis J., Woodruff R.H., Lakatos A., Li W.W., Dunning M.D., Zhao C., Marchionni M., Franklin R.J. Increasing local levels of neuregulin (glial growth factor-2) by direct infusion into areas of demyelination does not alter remyelination in the rat CNS. Eur. J. Neurosci. 2003, 18:2253-2264.
32. Perier O., Gregoire A. Electron microscopic features of multiple sclerosis lesions. Brain 1965, 88:937-952.
33. Prineas J.W., Connell F. Remyelination in multiple sclerosis. Ann. Neurol. 1979, 5:22-31.
34. Raine C.S., Wu E. Multiple sclerosis: remyelination in acute lesions. J. Neuropathol. Exp. Neurol. 1993, 52:199-204.
35. Roth G.A., Spada V., Hamill K., Bornstein M.B. Insulin-like growth factor I increases myelination and inhibits demyelination in cultured organotypic nerve tissue. Brain Res. Dev. Brain Res. 1995, 88:102-108.
36. Schmierer K., Parkes H.G., So P.W. Direct visualization of remyelination in multiple sclerosis using T2-weighted high-field MRI. Neurology 2009, 72:472.
37. Smith K.J., Blakemore W.F., McDonald W.I. The restoration of conduction by central remyelination. Brain 1981, 104:383-404.
38. Stankoff B., Demerens C., Goujet-Zalc C., Monge M., Peyron F., Mikoshiba K., Zalc B., Lubetzki C. Transcription of myelin basic protein promoted by regulatory elements in the proximal 5' sequence requires myelinogenesis. Mult. Scler. 1996, 2:125-132.
39. Stankoff B., Wang Y., Bottlaender M., Aigrot M.S., Dolle F., Wu C., Feinstein D., Huang G.F., Semah F., Mathis C.A., Klunk W., Gould R.M., Lubetzki C., Zalc B. Imaging of CNS myelin by positron-emission tomography. Proc. Natl. Acad. Sci. USA 2006, 103:9304-9309.
40. Stidworthy M.F., Genoud S., Li W.W., Leone D.P., Mantei N., Suter U., Franklin R.J. Notch1 and Jagged1 are expressed after CNS demyelination, but are not a major rate-determining factor during remyelination. Brain 2004, 127:1928-1941.
41. Vallstedt A., Klos J.M., Ericson J. Multiple dorsoventral origins of oligodendrocyte generation in the spinal cord and hindbrain. Neuron 2005, 45:55-67.
42. Wang Z., Colognato H., Ffrench-Constant C. Contrasting effects of mitogenic growth factors on myelination in neuron-oligodendrocyte co-cultures. Glia 2007, 55:537-545.
43. Watkins T.A., Emery B., Mulinyawe S., Barres B.A. Distinct stages of myelination regulated by gamma-secretase and astrocytes in a rapidly myelinating CNS coculture system. Neuron 2008, 60:555-569.
44. Woodruff R.H., Fruttiger M., Richardson W.D., Franklin R.J. Platelet-derived growth factor regulates oligodendrocyte progenitor numbers in adult CNS and their response following CNS demyelination. Mol. Cell. Neurosci. 2004, 25:252-262.