Perturbations in small molecule synthesis uncovers an iron-responsive secondary metabolite network in Aspergillus fumigatus

Frontiers in Microbiology

Volumn 5, Issue OCT, 2014, Pages

  Wiemann, Philipp ^a   Lechner, Beatrix E ^b   Baccile, Joshua A ^c   Velk, Thomas A ^a   Yin, Wen Bing ^a,e   Bok, Jin Woo ^a   Pakala, Suman ^d   Losada, Liliana ^d   Nierman, William C ^d   Schroeder, Frank C ^c   Haas, Hubertus ^b   Keller, Nancy P ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^c United States Department of Agriculture Agricultural Research Service and Boyce Thompson Institute for Plant Research   (United States)

^d J CRAIG VENTER INSTITUTE   (United States)

^e INSTITUTE OF MICROBIOLOGY   (China)

Author keywords

Aspergillus fumigatus; Gene regulation; HapX; Hexadehydroastechrome; Iron; Secondary metabolism; SreA

Indexed keywords

HEXADEHYDROASTECHROME; IRON DERIVATIVE; SIDEROPHORE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ARTICLE; ASPERGILLUS FUMIGATUS; BIOSYNTHESIS; FUNGAL CELL CULTURE; FUNGAL VIRULENCE; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENE REPRESSION; HOMEOSTASIS; IRON TRANSPORT; METABOLITE; NORTHERN BLOTTING; PHENOTYPE; POLYMERASE CHAIN REACTION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; RNA SEQUENCE; SECONDARY METABOLISM; SOUTHERN BLOTTING; STARVATION;

EID: 84987837266     PISSN: None     EISSN: 1664302X     Source Type: Journal    
DOI: 10.3389/fmicb.2014.00530     Document Type: Article

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