Siderophore biosynthesis but not reductive iron assimilation is essential for Aspergillus fumigatus virulence

Journal of Experimental Medicine

Volumn 200, Issue 9, 2004, Pages 1213-1219

  Schrettl, Markus ^a   Bignell, Elaine ^b   Kragl, Claudia ^a   Joechl, Chistoph ^a   Rogers, Tom ^b   Arst Jr , Herbert N ^b   Haynes, Ken ^b   Haas, Hubertus ^a  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Aspergillosis; Fungal pathogenicity; Iron uptake; Ornithine monooxygenase; Virulence factor

Indexed keywords

ANTIFUNGAL AGENT; HYDROXAMIC ACID; IRON; IRON PERMEASE; ORNITHINE N5 MONOOXYGENASE; PERMEASE; SIDEROPHORE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASPERGILLOSIS; ASPERGILLUS FUMIGATUS; CONTROLLED STUDY; DISEASE MODEL; FUNGAL VIRULENCE; IN VIVO STUDY; IRON DEFICIENCY; IRON KINETICS; IRON METABOLISM; IRON TRANSPORT; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

ANIMALS; ASPERGILLUS FUMIGATUS; BASE SEQUENCE; BLOTTING, NORTHERN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA PRIMERS; DNA, COMPLEMENTARY; FUNGAL PROTEINS; IRON; MICE; MIXED FUNCTION OXYGENASES; MOLECULAR SEQUENCE DATA; MUTATION; PHENOTYPE; PLASMIDS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA; SIDEROPHORES;

EID: 8644220677     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20041242     Document Type: Article

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