GPR91 deficiency exacerbates allergic contact dermatitis while reducing arthritic disease in mice

Allergy: European Journal of Allergy and Clinical Immunology

Volumn 72, Issue 3, 2017, Pages 444-452

  Rubic Schneider T ^a,b   Carballido Perrig, N ^a,b   Regairaz, C ^a   Raad, L ^a   Jost, S ^b,c   Rauld, C ^a   Christen, B ^a   Wieczorek, G ^a   Kreutzer, R ^a   Dawson, J ^a   Lametschwandner, G ^b,d   Littlewood Evans, A ^a   Carballido, J M ^a,b  

^a NOVARTIS PHARMA AG   (Switzerland)

^b NIBR   (Austria)

^c Valneva Austria GmbH   (Austria)

^d Apeiron Biologics Forschungs und Entwicklungsgesellschaft MbH   (Austria)

Author keywords

alarmins; allergy; autoimmunity; immunometabolism; succinate

Indexed keywords

G PROTEIN COUPLED RECEPTOR; OVALBUMIN; OXAZOLONE; SUCCINATE RECEPTOR GPR91; SUCCINIC ACID; UNCLASSIFIED DRUG; AUTACOID; BIOLOGICAL MARKER; CYTOKINE; GPR91 PROTEIN, MOUSE; IMMUNOGLOBULIN E;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTHRITIS; ARTICLE; CELL ACTIVATION; CELL DIFFERENTIATION; CONTROLLED STUDY; DISEASE EXACERBATION; HUMAN; HUMAN CELL; MAST CELL; MOUSE; NONHUMAN; PASSIVE SKIN ANAPHYLAXIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKIN ALLERGY; ANIMAL; BLOOD; DISEASE MODEL; GENE DELETION; GENETIC ASSOCIATION STUDY; GENETIC PREDISPOSITION; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; MACROPHAGE; MACROPHAGE ACTIVATION; METABOLISM; PATHOLOGY;

ANIMALS; ARTHRITIS; BIOMARKERS; CYTOKINES; DERMATITIS, ALLERGIC CONTACT; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; GENE DELETION; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; HUMANS; IMMUNOGLOBULIN E; INFLAMMATION MEDIATORS; MACROPHAGE ACTIVATION; MACROPHAGES; MAST CELLS; MICE; MICE, KNOCKOUT; RECEPTORS, G-PROTEIN-COUPLED;

EID: 84987643693     PISSN: 01054538     EISSN: 13989995     Source Type: Journal    
DOI: 10.1111/all.13005     Document Type: Article

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