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Volumn 213, Issue 9, 2016, Pages 1655-1662

GPR91 senses extracellular succinate released from inflammatory macrophages and exacerbates rheumatoid arthritis

(15) Littlewood Evans, Amanda a Sarret, Sophie a Apfel, Verena a Loesle, Perrine a Dawson, Janet a Zhang, Juan a Muller, Alban a Tigani, Bruno a Kneuer, Rainer a Patel, Saijel a Valeaux, Stephanie a Gommermann, Nina a Rubic Schneider, Tina a Junt, Tobias a Carballido, José M a

a NOVARTIS PHARMA AG (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR GPR91; INTERLEUKIN 1BETA; SUCCINIC ACID; UNCLASSIFIED DRUG; GPR91 PROTEIN, HUMAN; LIPOPOLYSACCHARIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOCRINE EFFECT; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DISEASE EXACERBATION; EXTRACELLULAR SPACE; FEMALE; HUMAN; HUMAN CELL; INFLAMMATION; MACROPHAGE; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PARACRINE SIGNALING; POSITIVE FEEDBACK; PRIORITY JOURNAL; RECEPTOR UPREGULATION; RHEUMATOID ARTHRITIS; SYNOVIAL FLUID; ANIMAL; ANTAGONISTS AND INHIBITORS; ARTHRITIS, RHEUMATOID; C57BL MOUSE; METABOLISM; PHYSIOLOGY; SECRETION (PROCESS); U-937 CELL LINE;

ANIMALS; ARTHRITIS, RHEUMATOID; FEMALE; HUMANS; INTERLEUKIN-1BETA; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MICE, INBRED C57BL; RECEPTORS, G-PROTEIN-COUPLED; SUCCINIC ACID; U937 CELLS;

EID: 84984799785 PISSN: 00221007 EISSN: 15409538 Source Type: Journal
DOI: 10.1084/jem.20160061 Document Type: Article

Times cited : (346)

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