Succinate causes α-SMA production through GPR91 activation in hepatic stellate cells

Biochemical and Biophysical Research Communications

Volumn 463, Issue 4, 2015, Pages 853-858

  Li, Ying Hui ^a   Woo, Sung Hoon ^b   Choi, Dae Hee ^a   Cho, Eun Hee ^a  

^a Kangwon National University   (South Korea)

^b University of Ulsan College of Medicine   (South Korea)

Author keywords

GPR91; Hepatic stellate cell; Nonalcoholic fatty liver disease; Succinate

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 1; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 91; MALONIC ACID; PALMITIC ACID; SMALL INTERFERING RNA; SUCCINATE DEHYDROGENASE; SUCCINIC ACID; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; ACTA2 PROTEIN, HUMAN; ACTIN; GPR91 PROTEIN, HUMAN; PRIMER DNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD LEVEL; CELL LYSATE; COMPARATIVE STUDY; ENZYME ACTIVITY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LIVER CELL; MALE; MOUSE; NONALCOHOLIC FATTY LIVER; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MODIFICATION; PROTEIN SYNTHESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STELLATE CELL; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL CULTURE; METABOLISM; NUCLEOTIDE SEQUENCE;

ANIMALIA; MUS;

ACTINS; ANIMALS; BASE SEQUENCE; CELLS, CULTURED; DNA PRIMERS; HEPATIC STELLATE CELLS; HUMANS; MALE; MICE; MICE, INBRED C57BL; NON-ALCOHOLIC FATTY LIVER DISEASE; RECEPTORS, G-PROTEIN-COUPLED; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SUCCINIC ACID;

EID: 84936985287     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.06.023     Document Type: Article

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