Polycomb Repressive Complex 2 Enacts Wnt Signaling in Intestinal Homeostasis and Contributes to the Instigation of Stemness in Diseases Entailing Epithelial Hyperplasia or Neoplasia

Stem Cells

Volumn 35, Issue 2, 2017, Pages 445-457

  Oittinen, Mikko ^a   Popp, Alina ^a,b   Kurppa, Kalle ^a   Lindfors, Katri ^a   Mäki, Markku ^a   Kaikkonen, Minna U ^c   Viiri, Keijo ^a  

^a TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^b CAROL DAVILA UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^c UNIVERSITY OF EASTERN FINLAND   (Finland)

Author keywords

Celiac disease; Crypt hyperplasia; Enterocyte; Intestinal stem cells; Polycomb Repressive Complex 2; Wnt signaling

Indexed keywords

GLUTEN; HISTONE H3; HISTONE H3 LYSINE 27; POLYCOMB REPRESSIVE COMPLEX 2; UNCLASSIFIED DRUG; WNT PROTEIN; HISTONE; LYSINE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELIAC DISEASE; CELL DIFFERENTIATION; CELL FATE; CELL KILLING; CELL PROLIFERATION; COLORECTAL ADENOMA; COLORECTAL CARCINOMA; CONTROLLED STUDY; EPITHELIUM HYPERPLASIA; GENE EXPRESSION; HISTONE METHYLATION; HOMEOSTASIS; HUMAN; HUMAN TISSUE; INTESTINAL STEM CELL; INTESTINE CELL; INTESTINE CRYPT; INTESTINE EPITHELIUM; INTESTINE TUMOR; INTESTINE VILLUS; MOUSE; NONHUMAN; NUTRIENT DYNAMICS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; STEM CELL NICHE; STEM CELL SELF-RENEWAL; WNT SIGNALING PATHWAY; ANIMAL; BIOLOGICAL MODEL; C57BL MOUSE; GENE EXPRESSION REGULATION; GENETICS; HYPERPLASIA; INTESTINE MUCOSA; METABOLISM; METHYLATION; PATHOLOGY; STEM CELL; WNT SIGNALING;

ANIMALS; CELIAC DISEASE; CELL DIFFERENTIATION; CELL PROLIFERATION; ENTEROCYTES; GENE EXPRESSION REGULATION, NEOPLASTIC; GLUTENS; HISTONES; HOMEOSTASIS; HUMANS; HYPERPLASIA; INTESTINAL MUCOSA; INTESTINAL NEOPLASMS; LYSINE; METHYLATION; MICE, INBRED C57BL; MODELS, BIOLOGICAL; POLYCOMB REPRESSIVE COMPLEX 2; STEM CELL NICHE; STEM CELLS; WNT SIGNALING PATHWAY;

EID: 84987624331     PISSN: 10665099     EISSN: 15494918     Source Type: Journal    
DOI: 10.1002/stem.2479     Document Type: Article

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