메뉴 건너뛰기




Volumn 144, Issue 2, 2013, Pages 381-391

Troy, a tumor necrosis factor receptor family member, interacts with Lgr5 to inhibit Wnt signaling in intestinal stem cells

Author keywords

Mouse model of colon cancer; TCF; Tnfrsf19; Catenin

Indexed keywords

APC PROTEIN; AZOXYMETHANE; BETA CATENIN; DEXTRAN SULFATE; G PROTEIN COUPLED RECEPTOR; LEUCINE RICH REPEAT CONTAINING G PROTEIN COUPLED RECEPTOR 5; LIGAND; MESSENGER RNA; TROY PROTEIN; TUMOR NECROSIS FACTOR RECEPTOR; UNCLASSIFIED DRUG; WNT3A PROTEIN; LGR5 PROTEIN, MOUSE; RNA; TNFRSF19 PROTEIN, MOUSE;

EID: 84881524604     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2012.10.048     Document Type: Article
Times cited : (90)

References (34)
  • 1
    • 0030592517 scopus 로고    scopus 로고
    • Lessons from hereditary colorectal cancer
    • Kinzler KW, Vogelstein B. Lessons from hereditary colorectal cancer. Cell 1996;87:159-170.
    • (1996) Cell , vol.87 , pp. 159-170
    • Kinzler, K.W.1    Vogelstein, B.2
  • 2
    • 0030975671 scopus 로고    scopus 로고
    • -/- colon carcinoma
    • Korinek V, Barker N, Morin PJ, et al. Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma. Science 1997;275:1784-1787.
    • (1997) Science , vol.275 , pp. 1784-1787
    • Korinek, V.1    Barker, N.2    Morin, P.J.3
  • 3
    • 77149174855 scopus 로고    scopus 로고
    • Wnt signaling from development to disease: Insights from model systems
    • Cadigan KM, Peifer M. Wnt signaling from development to disease: insights from model systems. Cold Spring Harb Perspect Biol 2009;1:a002881.
    • (2009) Cold Spring Harb Perspect Biol , vol.1
    • Cadigan, K.M.1    Peifer, M.2
  • 4
    • 0036007425 scopus 로고    scopus 로고
    • The intestinal epithelial stem cell
    • Marshman E, Booth C, Potten CS. The intestinal epithelial stem cell. BioEssays 2002;24:91-98.
    • (2002) BioEssays , vol.24 , pp. 91-98
    • Marshman, E.1    Booth, C.2    Potten, C.S.3
  • 5
    • 35548974423 scopus 로고    scopus 로고
    • Identification of stem cells in small intestine and colon by marker gene Lgr5
    • Barker N, van Es JH, Kuipers J, et al. Identification of stem cells in small intestine and colon by marker gene Lgr5. Nature 2007;449: 1003-1007.
    • (2007) Nature , vol.449 , pp. 1003-1007
    • Barker, N.1    Van Es, J.H.2    Kuipers, J.3
  • 6
    • 80054041585 scopus 로고    scopus 로고
    • A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable
    • Tian H, Biehs B, Warming S, et al. A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable. Nature 2011;478:255-259.
    • (2011) Nature , vol.478 , pp. 255-259
    • Tian, H.1    Biehs, B.2    Warming, S.3
  • 7
    • 35648969554 scopus 로고    scopus 로고
    • Wnt/beta-catenin is essential for intestinal homeostasis and maintenance of intestinal stem cells
    • Fevr T, Robine S, Louvard D, et al. Wnt/beta-catenin is essential for intestinal homeostasis and maintenance of intestinal stem cells. Mol Cell Biol 2007;27:7551-7559.
    • (2007) Mol Cell Biol , vol.27 , pp. 7551-7559
    • Fevr, T.1    Robine, S.2    Louvard, D.3
  • 8
    • 0031848068 scopus 로고    scopus 로고
    • Depletion of epithelial stemcell compartments in the small intestine of mice lacking Tcf-4
    • Korinek V, Barker N, Moerer P, et al. Depletion of epithelial stemcell compartments in the small intestine of mice lacking Tcf-4. Nat Genet 1998;19:379-383.
    • (1998) Nat Genet , vol.19 , pp. 379-383
    • Korinek, V.1    Barker, N.2    Moerer, P.3
  • 9
    • 0038064501 scopus 로고    scopus 로고
    • Expression of a member of tumor necrosis factor receptor superfamily, TROY, in the developing mouse brain
    • Hisaoka T, Morikawa Y, Kitamura T, et al. Expression of a member of tumor necrosis factor receptor superfamily, TROY, in the developing mouse brain. Brain Res Dev Brain Res 2003;143:105-109.
    • (2003) Brain Res Dev Brain Res , vol.143 , pp. 105-109
    • Hisaoka, T.1    Morikawa, Y.2    Kitamura, T.3
  • 10
    • 80051926611 scopus 로고    scopus 로고
    • Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling
    • de Lau W, Barker N, Low TY, et al. Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling. Nature 2011;476:293-297.
    • (2011) Nature , vol.476 , pp. 293-297
    • De Lau, W.1    Barker, N.2    Low, T.Y.3
  • 11
    • 80053560465 scopus 로고    scopus 로고
    • LGR4 and LGR5 are R-spondin receptors mediating Wnt/beta-catenin and Wnt/PCP signalling
    • Glinka A, Dolde C, Kirsch N, et al. LGR4 and LGR5 are R-spondin receptors mediating Wnt/beta-catenin and Wnt/PCP signalling. EMBO Rep 2011;12:1055-1061.
    • (2011) EMBO Rep , vol.12 , pp. 1055-1061
    • Glinka, A.1    Dolde, C.2    Kirsch, N.3
  • 12
    • 67349123408 scopus 로고    scopus 로고
    • Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
    • Sato T, Vries RG, Snippert HJ, et al. Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche. Nature 2009;459:262-265.
    • (2009) Nature , vol.459 , pp. 262-265
    • Sato, T.1    Vries, R.G.2    Snippert, H.J.3
  • 13
    • 66249092797 scopus 로고    scopus 로고
    • Dazap2 modulates transcription driven by the Wnt effector TCF-4
    • Lukas J, Mazna P, Valenta T, et al. Dazap2 modulates transcription driven by the Wnt effector TCF-4. Nucleic Acids Res 2009;37: 3007-3020.
    • (2009) Nucleic Acids Res , vol.37 , pp. 3007-3020
    • Lukas, J.1    Mazna, P.2    Valenta, T.3
  • 14
    • 0037737726 scopus 로고    scopus 로고
    • Wnt proteins are lipidmodified and can act as stem cell growth factors
    • Willert K, Brown JD, Danenberg E, et al. Wnt proteins are lipidmodified and can act as stem cell growth factors. Nature 2003; 423:448-452.
    • (2003) Nature , vol.423 , pp. 448-452
    • Willert, K.1    Brown, J.D.2    Danenberg, E.3
  • 15
    • 70350120570 scopus 로고    scopus 로고
    • In vivo detection of RNA-binding protein interactions with cognate RNA sequences by fluorescence resonance energy transfer
    • Huranova M, Jablonski JA, Benda A, et al. In vivo detection of RNA-binding protein interactions with cognate RNA sequences by fluorescence resonance energy transfer. RNA 2009;15:2063-2071.
    • (2009) RNA , vol.15 , pp. 2063-2071
    • Huranova, M.1    Jablonski, J.A.2    Benda, A.3
  • 16
    • 54449097840 scopus 로고    scopus 로고
    • Edar and Troy signalling pathways act redundantly to regulate initiation of hair follicle development
    • Pispa J, Pummila M, Barker PA, et al. Edar and Troy signalling pathways act redundantly to regulate initiation of hair follicle development. Hum Mol Genet 2008;17:3380-3391.
    • (2008) Hum Mol Genet , vol.17 , pp. 3380-3391
    • Pispa, J.1    Pummila, M.2    Barker, P.A.3
  • 17
    • 79953053041 scopus 로고    scopus 로고
    • Generation of two modified mouse alleles of the Hic1 tumor suppressor gene
    • Pospichalova V, Tureckova J, Fafilek B, et al. Generation of two modified mouse alleles of the Hic1 tumor suppressor gene. Genesis 2011;49:142-151.
    • (2011) Genesis , vol.49 , pp. 142-151
    • Pospichalova, V.1    Tureckova, J.2    Fafilek, B.3
  • 18
    • 0037416148 scopus 로고    scopus 로고
    • Nuclear export of the APC tumour suppressor controls beta-catenin function in transcription
    • Rosin-Arbesfeld R, Cliffe A, Brabletz T, et al. Nuclear export of the APC tumour suppressor controls beta-catenin function in transcription. EMBO J 2003;22:1101-1113.
    • (2003) EMBO J , vol.22 , pp. 1101-1113
    • Rosin-Arbesfeld, R.1    Cliffe, A.2    Brabletz, T.3
  • 19
    • 0037684769 scopus 로고    scopus 로고
    • Microarray analysis of somitogenesis reveals novel targets of different WNT signaling pathways in the somitic mesoderm
    • Buttitta L, Tanaka TS, Chen AE, et al. Microarray analysis of somitogenesis reveals novel targets of different WNT signaling pathways in the somitic mesoderm. Dev Biol 2003;258:91-104.
    • (2003) Dev Biol , vol.258 , pp. 91-104
    • Buttitta, L.1    Tanaka, T.S.2    Chen, A.E.3
  • 20
    • 0026562404 scopus 로고
    • Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene
    • Su LK, Kinzler KW, Vogelstein B, et al. Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene. Science 1992;256:668-670.
    • (1992) Science , vol.256 , pp. 668-670
    • Su, L.K.1    Kinzler, K.W.2    Vogelstein, B.3
  • 21
    • 27944442806 scopus 로고    scopus 로고
    • Dextran sodium sulfate strongly promotes colorectal carcinogenesis in Apc(Min/+) mice: Inflammatory stimuli by dextran sodium sulfate results in development of multiple colonic neoplasms
    • Tanaka T, Kohno H, Suzuki R, et al. Dextran sodium sulfate strongly promotes colorectal carcinogenesis in Apc(Min/+) mice: inflammatory stimuli by dextran sodium sulfate results in development of multiple colonic neoplasms. Int J Cancer 2006;118: 25-34.
    • (2006) Int J Cancer , vol.118 , pp. 25-34
    • Tanaka, T.1    Kohno, H.2    Suzuki, R.3
  • 22
    • 33749411672 scopus 로고    scopus 로고
    • Adenomatous polyposis coli (APC) is required for normal development of skin and thymus
    • Kuraguchi M, Wang XP, Bronson RT, et al. Adenomatous polyposis coli (APC) is required for normal development of skin and thymus. PLoS Genet 2006;2:e146.
    • (2006) PLoS Genet , vol.2
    • Kuraguchi, M.1    Wang, X.P.2    Bronson, R.T.3
  • 23
    • 0032923739 scopus 로고    scopus 로고
    • Generalized lacZ expression with the ROSA26 Cre reporter strain
    • Soriano P. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet 1999;21:70-71.
    • (1999) Nat Genet , vol.21 , pp. 70-71
    • Soriano, P.1
  • 24
    • 61349150537 scopus 로고    scopus 로고
    • Transcription factor achaete scute-like 2 controls intestinal stem cell fate
    • van der Flier LG, van Gijn ME, Hatzis P, et al. Transcription factor achaete scute-like 2 controls intestinal stem cell fate. Cell 2009; 136:903-912.
    • (2009) Cell , vol.136 , pp. 903-912
    • Van Der Flier, L.G.1    Van Gijn, M.E.2    Hatzis, P.3
  • 25
    • 78751644734 scopus 로고    scopus 로고
    • Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts
    • Sato T, van Es JH, Snippert HJ, et al. Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts. Nature 2011;469: 415-418.
    • (2011) Nature , vol.469 , pp. 415-418
    • Sato, T.1    Van Es, J.H.2    Snippert, H.J.3
  • 26
    • 0034617087 scopus 로고    scopus 로고
    • TROY, a newly identified member of the tumor necrosis factor receptor superfamily, exhibits a homology with Edar and is expressed in embryonic skin and hair follicles
    • Kojima T, Morikawa Y, Copeland NG, et al. TROY, a newly identified member of the tumor necrosis factor receptor superfamily, exhibits a homology with Edar and is expressed in embryonic skin and hair follicles. J Biol Chem 2000;275:20742-20747.
    • (2000) J Biol Chem , vol.275 , pp. 20742-20747
    • Kojima, T.1    Morikawa, Y.2    Copeland, N.G.3
  • 27
    • 79960990066 scopus 로고    scopus 로고
    • R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/betacatenin signaling
    • Carmon KS, Gong X, Lin Q, et al. R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/betacatenin signaling. Proc Natl Acad Sci U S A 2011;108:11452-11457.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 11452-11457
    • Carmon, K.S.1    Gong, X.2    Lin, Q.3
  • 28
    • 19944432743 scopus 로고    scopus 로고
    • TAJ/TROY, an orphan TNF receptor family member, binds Nogo-66 receptor 1 and regulates axonal regeneration
    • Shao Z, Browning JL, Lee X, et al. TAJ/TROY, an orphan TNF receptor family member, binds Nogo-66 receptor 1 and regulates axonal regeneration. Neuron 2005;45:353-359.
    • (2005) Neuron , vol.45 , pp. 353-359
    • Shao, Z.1    Browning, J.L.2    Lee, X.3
  • 29
    • 0034686080 scopus 로고    scopus 로고
    • TAJ, a novel member of the tumor necrosis factor receptor family, activates the c-Jun N-terminal kinase pathway and mediates caspase-independent cell death
    • Eby MT, Jasmin A, Kumar A, et al. TAJ, a novel member of the tumor necrosis factor receptor family, activates the c-Jun N-terminal kinase pathway and mediates caspase-independent cell death. J Biol Chem 2000;275:15336-15342.
    • (2000) J Biol Chem , vol.275 , pp. 15336-15342
    • Eby, M.T.1    Jasmin, A.2    Kumar, A.3
  • 30
    • 78649640148 scopus 로고    scopus 로고
    • TROY (TNFRSF19) is overexpressed in advanced glial tumors and promotes glioblastoma cell invasion via Pyk2-Rac1 signaling
    • Paulino VM, Yang Z, Kloss J, et al. TROY (TNFRSF19) is overexpressed in advanced glial tumors and promotes glioblastoma cell invasion via Pyk2-Rac1 signaling. Mol Cancer Res 2010;8:1558-1567.
    • (2010) Mol Cancer Res , vol.8 , pp. 1558-1567
    • Paulino, V.M.1    Yang, Z.2    Kloss, J.3
  • 31
    • 38349109862 scopus 로고    scopus 로고
    • Troy binding to lymphotoxinalpha activates NF kappa B mediated transcription
    • Hashimoto T, Schlessinger D, Cui CY. Troy binding to lymphotoxinalpha activates NF kappa B mediated transcription. Cell Cycle 2008;7:106-111.
    • (2008) Cell Cycle , vol.7 , pp. 106-111
    • Hashimoto, T.1    Schlessinger, D.2    Cui, C.Y.3
  • 32
    • 84860765166 scopus 로고    scopus 로고
    • ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner
    • Hao HX, Xie Y, Zhang Y, et al. ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner. Nature 2012;485: 195-200.
    • (2012) Nature , vol.485 , pp. 195-200
    • Hao, H.X.1    Xie, Y.2    Zhang, Y.3
  • 33
    • 84869864069 scopus 로고    scopus 로고
    • Redundant sources of Wnt regulate intestinal stem cells and promote formation of Paneth cells
    • Farin HF, Van Es JH, Clevers H. Redundant sources of Wnt regulate intestinal stem cells and promote formation of Paneth cells. Gastroenterology 2012;143:1518-1529.
    • (2012) Gastroenterology , vol.143 , pp. 1518-1529
    • Farin, H.F.1    Van Es, J.H.2    Clevers, H.3
  • 34
    • 42149183576 scopus 로고    scopus 로고
    • Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells
    • Hatzis P, van der Flier LG, van Driel MA, et al. Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells. Mol Cell Biol 2008;28:2732-2744.
    • (2008) Mol Cell Biol , vol.28 , pp. 2732-2744
    • Hatzis, P.1    Van Der Flier, L.G.2    Van Driel, M.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.