A PPARγ-Bnip3 axis couples adipose mitochondrial fusion-fission balance to systemic insulin sensitivity

Diabetes

Volumn 65, Issue 9, 2016, Pages 2591-2605

  Tol, Marc J ^a   Ottenhoff, Roelof ^a   Van Eijk, Marco ^a,b   Zelcer, Noam ^a   Aten, Jan ^a   Houten, Sander M ^a,c   Geerts, Dirk ^a   Van Roomen, Cindy ^a   Bierlaagh, Marlou C ^a   Scheij, Saskia ^a   Hoeksema, Marten A ^a   Aerts, Johannes M ^b   Bogan, Jonathan S ^d   Dorn, Gerald W ^e   Argmann, Carmen A ^a,c   Verhoeven, Arthur J ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b LEIDEN UNIVERSITY   (Netherlands)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DYNAMIN RELATED PROTEIN 1; FATTY ACID; GLUCOSE; GLUCOSE TRANSPORTER 4; INSULIN; LEPTIN; MDIVI 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN; PROTEIN BNIP3; PROTEIN INHIBITOR; REACTIVE OXYGEN METABOLITE; SHORT HAIRPIN RNA; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; BNIP3 PROTEIN, MOUSE; MEMBRANE PROTEIN; MITOCHONDRIAL PROTEIN;

3T3 CELL LINE; ADAPTATION; ADIPOCYTE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOENERGY; BROWN ADIPOSE TISSUE; CELL DIFFERENTIATION; CONTROLLED STUDY; DIET INDUCED OBESITY; DISEASE PREDISPOSITION; FAT INTAKE; FATTY ACID OXIDATION; FATTY LIVER; GENE SILENCING; GENETIC VARIATION; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; IN VITRO STUDY; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIPID STORAGE; MALE; MEMBRANE FUSION; MITOCHONDRIAL DYNAMICS; MITOCHONDRIAL FUSION FISSION BALANCE; MITOCHONDRIAL RESPIRATION; MOUSE; MOUSE MODEL; NONHUMAN; OB/OB MOUSE; OXIDATIVE STRESS; POPULATION GENETICS; PRIORITY JOURNAL; PROTEIN FUNCTION; SENSITIZATION; TRANSCRIPTION INITIATION; WHITE ADIPOSE TISSUE; 3T3-L1 CELL LINE; ANIMAL; C57BL MOUSE; CELL LINE; FEMALE; FLUORESCENCE MICROSCOPY; GENETICS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; KNOCKOUT MOUSE; METABOLISM; MITOCHONDRION; OBESITY; PHYSIOLOGY; RADIOIMMUNOPRECIPITATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

3T3-L1 CELLS; ADIPOCYTES; ANIMALS; CELL DIFFERENTIATION; CELL LINE; FEMALE; GLUCOSE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; INSULIN; INSULIN RESISTANCE; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, FLUORESCENCE; MITOCHONDRIA; MITOCHONDRIAL DYNAMICS; MITOCHONDRIAL PROTEINS; OBESITY; PPAR GAMMA; RADIOIMMUNOPRECIPITATION ASSAY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 84987597411     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db16-0243     Document Type: Article

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