Oxygen radicals shaping evolution: Why fatty acid catabolism leads to peroxisomes while neurons do without it: FADH2/NADH flux ratios determining mitochondrial radical formation were crucial for the eukaryotic invention of peroxisomes and catabolic tissue differentiation

BioEssays

Volumn 33, Issue 2, 2011, Pages 88-94

  Speijer, Dave ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

Beta oxidation; LECA; Mitochondria; Oxygen radicals; Peroxisomes

Indexed keywords

FATTY ACID; FLAVINE ADENINE NUCLEOTIDE; GLUCOSE; OXYGEN RADICAL; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; UNSATURATED FATTY ACID;

ARTICLE; CATABOLISM; ELECTRON; EUKARYOTE; EUKARYOTIC CELL; EVOLUTION; FATTY ACID METABOLISM; FATTY ACID OXIDATION; KINETICS; MITOCHONDRION; NERVE CELL; NONHUMAN; PEROXISOME; RESPIRATORY CHAIN; TISSUE DIFFERENTIATION;

BIOLOGICAL EVOLUTION; CELL DIFFERENTIATION; ELECTRON TRANSPORT; EUKARYOTA; FATTY ACIDS; FLAVIN-ADENINE DINUCLEOTIDE; GLUCOSE; KINETICS; MITOCHONDRIA; MODELS, BIOLOGICAL; NAD; NEURONS; OXIDATION-REDUCTION; PEROXISOMES; REACTIVE OXYGEN SPECIES;

EUKARYOTA;

EID: 78651427556     PISSN: 02659247     EISSN: 15211878     Source Type: Journal    
DOI: 10.1002/bies.201000097     Document Type: Article

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