Hepatic Bmal1 regulates rhythmic mitochondrial dynamics and promotes metabolic fitness

Cell Metabolism

Volumn 22, Issue 4, 2015, Pages 709-720

  Jacobi, David ^a   Liu, Sihao ^a,b   Burkewitz, Kristopher ^a   Kory, Nora ^a   Knudsen, Nelson H ^a   Alexander, Ryan K ^a   Unluturk, Ugur ^a,c   Li, Xiaobo ^a,d   Kong, Xiaohui ^a   Hyde, Alexander L ^a   Gangl, Matthew R ^a   Mair, William B ^a   Lee, Chih Hao ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^c ANKARA UNIVERSITY   (Turkey)

^d FUDAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; FATTY ACID; FIS1 PROTEIN; PROTEIN; TRANSCRIPTION FACTOR ARNTL; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; ARNTL PROTEIN, MOUSE; CAENORHABDITIS ELEGANS PROTEIN; CLOCK PROTEIN, MOUSE; CRY1 PROTEIN, MOUSE; CRYPTOCHROME; FIS1 PROTEIN, MOUSE; INSULIN; MITOCHONDRIAL PROTEIN; TRANSCRIPTION FACTOR CLOCK;

AEROBIC METABOLISM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BASAL METABOLIC RATE; BIOENERGY; BIOGENESIS; CHOLESTEROL BLOOD LEVEL; CHROMATIN IMMUNOPRECIPITATION; CIRCADIAN RHYTHM; CONTROLLED STUDY; DNA CONTENT; ELECTRON MICROSCOPY; ENERGY METABOLISM; ENZYME PHOSPHORYLATION; GENE ONTOLOGY; GLUCOSE TOLERANCE TEST; INSULIN RESISTANCE; INSULIN TOLERANCE TEST; LIFESPAN; LIPID DIET; LIVER; LIVER CELL; MALE; METABOLIC RHYTHM; METABOLISM; MITOCHONDRIAL DYNAMICS; MITOCHONDRIAL RESPIRATION; MITOCHONDRION SWELLING; MITOPHAGY; MOUSE; NONHUMAN; NUTRIENT; NUTRIENT AVAILABILITY; OXIDATIVE STRESS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN CARBONYLATION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY MECHANISM; TEMPERATURE; TIME LAPSE IMAGING; TRIACYLGLYCEROL BLOOD LEVEL; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CAENORHABDITIS ELEGANS; CELL CULTURE; CYTOLOGY; DEFICIENCY; GENETICS; KNOCKOUT MOUSE; LONGEVITY; MITOCHONDRION; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

ANIMALS; ARNTL TRANSCRIPTION FACTORS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CELLS, CULTURED; CLOCK PROTEINS; CRYPTOCHROMES; DIET, HIGH-FAT; HEPATOCYTES; INSULIN; LIVER; LONGEVITY; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOCHONDRIA; MITOCHONDRIAL DYNAMICS; MITOCHONDRIAL PROTEINS; OXIDATIVE STRESS; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

EID: 84943450709     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2015.08.006     Document Type: Article

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