Cryo-EM reveals the conformation of a substrate analogue in the human 20S proteasome core

Nature Communications

Volumn 6, Issue , 2015, Pages

  Da Fonseca, Paula C A ^a   Morris, Edward P ^b  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^b INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

20S PROTEASOME; PROTEASOME; UNCLASSIFIED DRUG; ADAMANTANE; ADAMANTANEACETYL-(6-AMINOHEXANOYL)3-(LEUCYL)3-VINYLMETHYL-SULFONE; PROTEASOME INHIBITOR; PROTEIN BINDING; SULFONE;

CELLS AND CELL COMPONENTS; ELECTRON MICROSCOPY; FUNCTIONAL GROUP; INHIBITOR; LIGAND; PROTEIN; SUBSTRATE;

ARTICLE; CHEMICAL ANALYSIS; CRYOELECTRON MICROSCOPY; PROTEIN FUNCTION; PROTEIN STRUCTURE; SINGLE PARTICLE ANALYSIS; ANALOGS AND DERIVATIVES; HUMAN; IMAGE PROCESSING; METABOLISM; PROCEDURES; PROTEIN CONFORMATION; ULTRASTRUCTURE;

ADAMANTANE; CRYOELECTRON MICROSCOPY; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEASOME INHIBITORS; PROTEIN BINDING; PROTEIN CONFORMATION; SULFONES;

EID: 84986883266     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms8573     Document Type: Article

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