CC-chemokine ligand 2 (CCL2) suppresses high density lipoprotein (HDL) internalization and cholesterol efflux via CC-chemokine receptor 2 (CCR2) induction and p42/44 mitogen-activated protein kinase (MAPK) activation in human endothelial cells

Journal of Biological Chemistry

Volumn 291, Issue 37, 2016, Pages 19532-19544

  Sun, Run Lu ^a   Huang, Can Xia ^b   Bao, Jin Lan ^a   Jiang, Jie Yu ^a   Zhang, Bo ^a   Zhou, Shu Xian ^a   Cai, Wei Bin ^c   Wang, Hong ^d,e   Wang, Jing Feng ^a   Zhang, Yu Ling ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b Intensive Care Unit   (China)

^c Key Laboratory of Cardiac Electrophysiology and Arrhythmia in Guangdong Province   (China)

^d SUN YAT SEN UNIVERSITY   (China)

^e TEMPLE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ACTIVATION; COMPUTER AIDED DIAGNOSIS; CYTOLOGY; DISEASES; ENDOTHELIAL CELLS; ENZYMES; LIGANDS; LIPOPROTEINS;

CELLULAR INTERNALIZATION; CHOLESTEROL TRANSPORT; CORONARY ARTERY DISEASE; HIGH-DENSITY LIPOPROTEINS; HUMAN CORONARY ARTERY ENDOTHELIAL CELLS; HUMAN ENDOTHELIAL CELLS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; MITOGEN ACTIVATED PROTEIN KINASE;

CHOLESTEROL;

APOLIPOPROTEIN A1; CHEMOKINE RECEPTOR CCR2; CHOLESTEROL; HIGH DENSITY LIPOPROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MONOCYTE CHEMOTACTIC PROTEIN 1; SMALL INTERFERING RNA; APOA1 PROTEIN, HUMAN; CCL2 PROTEIN, HUMAN; CCR2 PROTEIN, HUMAN;

ARTERY ENDOTHELIUM; ARTICLE; ATHEROSCLEROSIS; CHOLESTEROL TRANSPORT; CORONARY ARTERY DISEASE; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; INTERNALIZATION; LIPOPROTEIN METABOLISM; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; UMBILICAL VEIN ENDOTHELIAL CELL; VASCULAR ENDOTHELIAL CELL; FEMALE; GENE EXPRESSION REGULATION; MALE; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION;

APOLIPOPROTEIN A-I; CHEMOKINE CCL2; CHOLESTEROL; CORONARY ARTERY DISEASE; ENZYME ACTIVATION; FEMALE; GENE EXPRESSION REGULATION; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; LIPOPROTEINS, HDL; MALE; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; RECEPTORS, CCR2;

EID: 84986883156     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M116.714279     Document Type: Article

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