메뉴 건너뛰기




Volumn 12, Issue 1, 2015, Pages

Dimethylfumarate protects against TNF-α-induced secretion of inflammatory cytokines in human endothelial cells

Author keywords

Dimethylfumarate; I B ; MCP 1; p65; TNF

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; FUMARIC ACID DIMETHYL ESTER; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; I KAPPA B ALPHA; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; PLATELET DERIVED GROWTH FACTOR BB; RANTES; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 84938793861     PISSN: None     EISSN: 14769255     Source Type: Journal    
DOI: 10.1186/s12950-015-0094-z     Document Type: Article
Times cited : (23)

References (30)
  • 1
    • 65549139306 scopus 로고    scopus 로고
    • Angiogenesis drives psoriasis pathogenesis
    • 1:CAS:528:DC%2BD1MXotV2ju7k%3D 2697548 19563608
    • Heidenreich R, Röcken M, Ghoreschi K. Angiogenesis drives psoriasis pathogenesis. Int J Exp Pathol. 2009;90(3):232-48.
    • (2009) Int J Exp Pathol , vol.90 , Issue.3 , pp. 232-248
    • Heidenreich, R.1    Röcken, M.2    Ghoreschi, K.3
  • 2
    • 25444522479 scopus 로고    scopus 로고
    • Role of angiogenesis in cardiovascular disease: a critical appraisal
    • 16172288
    • Khurana R, Simons M, Martin JF, Zachary IC. Role of angiogenesis in cardiovascular disease: a critical appraisal. Circulation. 2005;112(12):1813-24.
    • (2005) Circulation , vol.112 , Issue.12 , pp. 1813-1824
    • Khurana, R.1    Simons, M.2    Martin, J.F.3    Zachary, I.C.4
  • 3
    • 84906605908 scopus 로고    scopus 로고
    • Blockade of the monocyte chemoattractant protein-1 receptor pathway ameliorates myocardial injury in animal models of ischemia and reperfusion
    • 1:CAS:528:DC%2BC2cXhsVyqt7%2FL 25170996
    • Al-Amran FG, Manson MZ, Hanley TK, Hainz DL. Blockade of the monocyte chemoattractant protein-1 receptor pathway ameliorates myocardial injury in animal models of ischemia and reperfusion. Pharmacology. 2014;93(5-6):296-302.
    • (2014) Pharmacology , vol.93 , Issue.5-6 , pp. 296-302
    • Al-Amran, F.G.1    Manson, M.Z.2    Hanley, T.K.3    Hainz, D.L.4
  • 4
    • 84930177360 scopus 로고    scopus 로고
    • The varying faces of IL-6: From cardiac protection to cardiac failure
    • 1:CAS:528:DC%2BC2MXhtF2msrc%3D 25649043
    • Fontes JA, Rose NR, Ciháková D. The varying faces of IL-6: From cardiac protection to cardiac failure. Cytokine. 2015;74:62.
    • (2015) Cytokine , vol.74 , pp. 62
    • Fontes, J.A.1    Rose, N.R.2    Ciháková, D.3
  • 5
    • 70449253356 scopus 로고
    • Heilung von Psoriasis vulgaris
    • 1:STN:280:DyaG1M%2Fntlaktg%3D%3D
    • Schweckendiek W. Heilung von Psoriasis vulgaris. Med Msch. 1959;13:103.
    • (1959) Med Msch , vol.13 , pp. 103
    • Schweckendiek, W.1
  • 6
    • 84907416974 scopus 로고    scopus 로고
    • Dimethyl fumarate (Tecfidera) for multiple sclerosis
    • Robinson A. Dimethyl fumarate (Tecfidera) for multiple sclerosis. Nurse Pract. 2009;39(7):10-1.
    • (2009) Nurse Pract , vol.39 , Issue.7 , pp. 10-11
    • Robinson, A.1
  • 7
    • 0035725785 scopus 로고    scopus 로고
    • The antipsoriatic drug dimethylfumarate strongly suppresses chemokine production in human keratinocytes and peripheral blood mononuclear cells
    • 1:CAS:528:DC%2BD3MXltFeiu70%3D 11422029
    • Stoof TJ, Flier J, Sampat S, Nieboer C, Tensen CP, Boorsma DM. The antipsoriatic drug dimethylfumarate strongly suppresses chemokine production in human keratinocytes and peripheral blood mononuclear cells. Br J Dermatol. 2001;144(6):1114-20.
    • (2001) Br J Dermatol , vol.144 , Issue.6 , pp. 1114-1120
    • Stoof, T.J.1    Flier, J.2    Sampat, S.3    Nieboer, C.4    Tensen, C.P.5    Boorsma, D.M.6
  • 8
    • 0028029067 scopus 로고
    • Antiproliferative and cytotoxic profiles of antipsoriatic fumaric acid derivatives in keratinocyte cultures
    • 8157084
    • Sebök B, Bonnekoh B, Geisel J, Mahrle G. Antiproliferative and cytotoxic profiles of antipsoriatic fumaric acid derivatives in keratinocyte cultures. Eur J Pharmacol. 1994;270(1):79-87.
    • (1994) Eur J Pharmacol , vol.270 , Issue.1 , pp. 79-87
    • Sebök, B.1    Bonnekoh, B.2    Geisel, J.3    Mahrle, G.4
  • 9
    • 0345732760 scopus 로고    scopus 로고
    • Dimethylfumarate is a potent inducer of apoptosis in human T cells
    • 1:CAS:528:DC%2BD2cXhtVaksA%3D%3D 14675187
    • Treumer F, Zhu K, Gläser R, Mrowietz U. Dimethylfumarate is a potent inducer of apoptosis in human T cells. J Invest Dermatol. 2003;121(6):1383-8.
    • (2003) J Invest Dermatol , vol.121 , Issue.6 , pp. 1383-1388
    • Treumer, F.1    Zhu, K.2    Gläser, R.3    Mrowietz, U.4
  • 10
    • 84910660431 scopus 로고    scopus 로고
    • Dimethyl fumarate protects pancreatic islet cells and non-endocrine tissue in L-arginine-induced chronic pancreatitis
    • 4157838 25198679
    • Robles L, Vaziri ND, Li S, Masuda Y, Takasu C, Takasu M, et al. Dimethyl fumarate protects pancreatic islet cells and non-endocrine tissue in L-arginine-induced chronic pancreatitis. PLoS One. 2014;9(9):e107111.
    • (2014) PLoS One , vol.9 , Issue.9
    • Robles, L.1    Vaziri, N.D.2    Li, S.3    Masuda, Y.4    Takasu, C.5    Takasu, M.6
  • 11
    • 0030913951 scopus 로고    scopus 로고
    • Dimethylfumarate is an inhibitor of cytokine-induced E-selectin, VCAM-1, and ICAM-1 expression in human endothelial cells
    • 1:CAS:528:DyaK2sXjt1ygu7k%3D 9168952
    • Vandermeeren M, Janssens S, Borgers M, Geysen J. Dimethylfumarate is an inhibitor of cytokine-induced E-selectin, VCAM-1, and ICAM-1 expression in human endothelial cells. Biochem Biophys Res Commun. 1997;234(1):19-23.
    • (1997) Biochem Biophys Res Commun , vol.234 , Issue.1 , pp. 19-23
    • Vandermeeren, M.1    Janssens, S.2    Borgers, M.3    Geysen, J.4
  • 12
    • 0035675207 scopus 로고    scopus 로고
    • Dimethylfumarate inhibits tumor-necrosis-factor-induced CD62E expression in an NF-kappa B-dependent manner
    • 1:CAS:528:DC%2BD38XjtVahtQ%3D%3D 11886496
    • Loewe R, Pillinger M, de Martin R, Mrowietz U, Gröger M, Holnthoner W, et al. Dimethylfumarate inhibits tumor-necrosis-factor-induced CD62E expression in an NF-kappa B-dependent manner. J Invest Dermatol. 2001;117(6):1363-8.
    • (2001) J Invest Dermatol , vol.117 , Issue.6 , pp. 1363-1368
    • Loewe, R.1    Pillinger, M.2    De Martin, R.3    Mrowietz, U.4    Gröger, M.5    Holnthoner, W.6
  • 13
    • 0036569398 scopus 로고    scopus 로고
    • Dimethylfumarate inhibits TNF-induced nuclear entry of NF-kappa B/p65 in human endothelial cells
    • 1:CAS:528:DC%2BD38Xjt12jurk%3D 11971029
    • Loewe R, Holnthoner W, Gröger M, Pillinger M, Gruber F, Mechtcheriakova D, et al. Dimethylfumarate inhibits TNF-induced nuclear entry of NF-kappa B/p65 in human endothelial cells. J Immunol. 2002;168(9):4781-7.
    • (2002) J Immunol , vol.168 , Issue.9 , pp. 4781-4787
    • Loewe, R.1    Holnthoner, W.2    Gröger, M.3    Pillinger, M.4    Gruber, F.5    Mechtcheriakova, D.6
  • 14
    • 79956001811 scopus 로고    scopus 로고
    • Suppression of VEGFR2 expression in human endothelial cells by dimethylfumarate treatment: evidence for anti-angiogenic action
    • 1:CAS:528:DC%2BC3MXmtV2jtbc%3D 21430706
    • Meissner M, Doll M, Hrgovic I, Reichenbach G, König V, Hailemariam-Jahn T, et al. Suppression of VEGFR2 expression in human endothelial cells by dimethylfumarate treatment: evidence for anti-angiogenic action. J Invest Dermatol. 2011;131(6):1356-64.
    • (2011) J Invest Dermatol , vol.131 , Issue.6 , pp. 1356-1364
    • Meissner, M.1    Doll, M.2    Hrgovic, I.3    Reichenbach, G.4    König, V.5    Hailemariam-Jahn, T.6
  • 16
    • 84903824542 scopus 로고    scopus 로고
    • Dimethylfumarate attenuates restenosis after acute vascular injury by cell-specific and Nrf2-dependent mechanisms
    • 1:CAS:528:DC%2BC2cXht1Kqt7bO 4087186 25009787
    • Oh CJ, Park S, Kim JY, Kim HJ, Jeoung NH, Choi YK, et al. Dimethylfumarate attenuates restenosis after acute vascular injury by cell-specific and Nrf2-dependent mechanisms. Redox Biol. 2014;2:855-64.
    • (2014) Redox Biol , vol.2 , pp. 855-864
    • Oh, C.J.1    Park, S.2    Kim, J.Y.3    Kim, H.J.4    Jeoung, N.H.5    Choi, Y.K.6
  • 17
    • 84904246971 scopus 로고    scopus 로고
    • Fumaric acid esters can block pro-inflammatory actions of human CRP and ameliorate metabolic disturbances in transgenic spontaneously hypertensive rats
    • 4092096 25010431
    • Šilhavý J, Zídek V, Mlejnek P, Landa V, Šimáková M, Strnad H, et al. Fumaric acid esters can block pro-inflammatory actions of human CRP and ameliorate metabolic disturbances in transgenic spontaneously hypertensive rats. PLoS One. 2014;9(7):e101906.
    • (2014) PLoS One , vol.9 , Issue.7
    • Šilhavý, J.1    Zídek, V.2    Mlejnek, P.3    Landa, V.4    Šimáková, M.5    Strnad, H.6
  • 18
    • 84863244462 scopus 로고    scopus 로고
    • Fumarate is cardioprotective via activation of the Nrf2 antioxidant pathway
    • 1:CAS:528:DC%2BC38XjsFOhsro%3D 3314920 22405071
    • Ashrafian H, Czibik G, Bellahcene M, Aksentijević D, Smith AC, Mitchell SJ, et al. Fumarate is cardioprotective via activation of the Nrf2 antioxidant pathway. Cell Metab. 2012;15(3):361-71.
    • (2012) Cell Metab , vol.15 , Issue.3 , pp. 361-371
    • Ashrafian, H.1    Czibik, G.2    Bellahcene, M.3    Aksentijević, D.4    Smith, A.C.5    Mitchell, S.J.6
  • 20
    • 84903397422 scopus 로고    scopus 로고
    • Endothelial dysfunction in chronic inflammatory diseases
    • 4139785 24968272
    • Steyers 3rd CM, Miller Jr FJ. Endothelial dysfunction in chronic inflammatory diseases. Int J Mol Sci. 2014;15(7):11324-49.
    • (2014) Int J Mol Sci , vol.15 , Issue.7 , pp. 11324-11349
    • Steyers, C.M.1    Miller, F.J.2
  • 21
    • 84891631575 scopus 로고    scopus 로고
    • Cardiovascular risk and psoriasis: beyond the traditional risk factors
    • 24161194
    • Coumbe AG, Pritzker MR, Duprez DA. Cardiovascular risk and psoriasis: beyond the traditional risk factors. Am J Med. 2014;127(1):12-8.
    • (2014) Am J Med , vol.127 , Issue.1 , pp. 12-18
    • Coumbe, A.G.1    Pritzker, M.R.2    Duprez, D.A.3
  • 23
    • 79952200120 scopus 로고    scopus 로고
    • Inhibition of NF-κB and AP-1 by dimethylfumarate correlates with down-regulated IL-6 secretion and proliferation in human lung fibroblasts
    • 21136335
    • Seidel P, Merfort I, Tamm M, Roth M. Inhibition of NF-κB and AP-1 by dimethylfumarate correlates with down-regulated IL-6 secretion and proliferation in human lung fibroblasts. Swiss Med Wkly. 2010;140:w13132.
    • (2010) Swiss Med Wkly , vol.140
    • Seidel, P.1    Merfort, I.2    Tamm, M.3    Roth, M.4
  • 24
    • 60549098432 scopus 로고    scopus 로고
    • Role of TNF-alpha in vascular dysfunction
    • 1:CAS:528:DC%2BD1MXis1OjtA%3D%3D
    • Zhang H, Park Y, Wu J, Xp C, Lee S, Yang J, et al. Role of TNF-alpha in vascular dysfunction. Clin Sci (Lond). 2009;116(3):219-30.
    • (2009) Clin Sci (Lond) , vol.116 , Issue.3 , pp. 219-230
    • Zhang, H.1    Park, Y.2    Wu, J.3    Xp, C.4    Lee, S.5    Yang, J.6
  • 25
    • 77958010498 scopus 로고    scopus 로고
    • DMF inhibits PDGF-BB induced airway smooth muscle cell proliferation through induction of heme-oxygenase-1
    • 2972257 20961405
    • Seidel P, Goulet S, Hostettler K, Tamm M, Roth M. DMF inhibits PDGF-BB induced airway smooth muscle cell proliferation through induction of heme-oxygenase-1. Respir Res. 2010;11:145.
    • (2010) Respir Res , vol.11 , pp. 145
    • Seidel, P.1    Goulet, S.2    Hostettler, K.3    Tamm, M.4    Roth, M.5
  • 26
    • 34547890303 scopus 로고    scopus 로고
    • Dimethylfumarate specifically inhibits the mitogen and stress-activated kinases 1 and 2 (MSK1/2): possible role for its anti-psoriatic effect
    • 1:CAS:528:DC%2BD2sXptVWht74%3D 17495961
    • Gesser B, Johansen C, Rasmussen MK, Funding AT, Otkjaer K, Kjellerup RB, et al. Dimethylfumarate specifically inhibits the mitogen and stress-activated kinases 1 and 2 (MSK1/2): possible role for its anti-psoriatic effect. J Invest Dermatol. 2007;127(9):2129-37.
    • (2007) J Invest Dermatol , vol.127 , Issue.9 , pp. 2129-2137
    • Gesser, B.1    Johansen, C.2    Rasmussen, M.K.3    Funding, A.T.4    Otkjaer, K.5    Kjellerup, R.B.6
  • 27
    • 84937397576 scopus 로고    scopus 로고
    • Dimethyl fumarate induces necroptosis in colon cancer cells through GSH depletion/ROS increase/MAPKs activation pathway
    • Xie X, Zhao Y, Ma CY, Xu XM, Zhang YQ, Wang CG, et al. Dimethyl fumarate induces necroptosis in colon cancer cells through GSH depletion/ROS increase/MAPKs activation pathway. Br J Pharmacol. 2015. doi: 10.1111/bph.13184.
    • (2015) Br J Pharmacol
    • Xie, X.1    Zhao, Y.2    Ma, C.Y.3    Xu, X.M.4    Zhang, Y.Q.5    Wang, C.G.6
  • 28
    • 42949171833 scopus 로고    scopus 로고
    • Signalling, inflammation and arthritis: NF-kappaB and its relevance to arthritis and inflammation
    • 1:CAS:528:DC%2BD1cXkvFymtL0%3D
    • Simmonds RE, Foxwell BM. Signalling, inflammation and arthritis: NF-kappaB and its relevance to arthritis and inflammation. Rheumatology (Oxford). 2008;47(5):584-90.
    • (2008) Rheumatology (Oxford) , vol.47 , Issue.5 , pp. 584-590
    • Simmonds, R.E.1    Foxwell, B.M.2
  • 29
    • 84865009934 scopus 로고    scopus 로고
    • Dimethyl fumarate inhibits dendritic cell maturation via nuclear factor κB (NF-κB) and extracellular signal-regulated kinase 1 and 2 (ERK1/2) and mitogen stress-activated kinase 1 (MSK1) signaling
    • 1:CAS:528:DC%2BC38XhtFOksbnE 3431702 22733812
    • Peng H, Guerau-de-Arellano M, Mehta VB, Yang Y, Huss DJ, Papenfuss TL, et al. Dimethyl fumarate inhibits dendritic cell maturation via nuclear factor κB (NF-κB) and extracellular signal-regulated kinase 1 and 2 (ERK1/2) and mitogen stress-activated kinase 1 (MSK1) signaling. J Biol Chem. 2012;287(33):28017-26.
    • (2012) J Biol Chem , vol.287 , Issue.33 , pp. 28017-28026
    • Peng, H.1    Guerau-De-Arellano, M.2    Mehta, V.B.3    Yang, Y.4    Huss, D.J.5    Papenfuss, T.L.6
  • 30
    • 27144459692 scopus 로고    scopus 로고
    • hosphorylation of RelA/p65 on serine 536 defines an I{kappa}B{alpha}-independent NF-{kappa}B pathway
    • 1:CAS:528:DC%2BD2MXhtVyksrzN 16105840
    • Sasaki CY, Barberi TJ, Ghosh P, Longo DL. hosphorylation of RelA/p65 on serine 536 defines an I{kappa}B{alpha}-independent NF-{kappa}B pathway. J Biol Chem. 2005;280(41):34538-47.
    • (2005) J Biol Chem , vol.280 , Issue.41 , pp. 34538-34547
    • Sasaki, C.Y.1    Barberi, T.J.2    Ghosh, P.3    Longo, D.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.