Interleukin-6 protects human macrophages from cellular cholesterol accumulation and attenuates the proinflammatory response

Journal of Biological Chemistry

Volumn 286, Issue 35, 2011, Pages 30926-30936

  Frisdal, Eric ^a,b   Lesnik, Philippe ^a,b   Olivier, Maryline ^a,b   Robillard, Paul ^a,b   Chapman, M John ^a,b   Huby, Thierry ^a,b   Guerin, Maryse ^a,b   Le Goff, Wilfried ^a,b  

^a INSERM   (France)

^b SORBONNE UNIVERSITÉ   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-INFLAMMATORIES; APOPTOTIC; APOPTOTIC CELLS; ATHEROGENESIS; ATHEROSCLEROTIC LESIONS; ATHEROSCLEROTIC PLAQUE; CELLULAR CHOLESTEROL; CELLULAR CHOLESTEROL EFFLUX; CHOLESTEROL EFFLUX; CYTOKINES; FOAM CELLS; FREE CHOLESTEROLS; HUMAN MACROPHAGES; INTERLEUKIN-6; MONOCYTE-DERIVED MACROPHAGES; PHAGOCYTIC CELLS; PHAGOCYTOSE; PLAQUE PROGRESSION; PROINFLAMMATORY; PROINFLAMMATORY RESPONSE; SECRETORY PRODUCTS; SELECTIVE INHIBITION; SIGNALING PATHWAYS; TRANSGLUTAMINASE 2;

AMINO ACIDS; CELLULAR MANUFACTURING; CHOLESTEROL; ENZYME INHIBITION; PHYSIOLOGY;

MACROPHAGES;

ABC TRANSPORTER A1; APOLIPOPROTEIN A1; CYTOKINE; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 6; JANUS KINASE 2; LIPID; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE 2; PROTEIN TYROSINE KINASE; STAT3 PROTEIN; THROMBOSPONDIN 1;

ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; CELL PROTECTION; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; CYTOKINE RELEASE; HUMAN; HUMAN CELL; LIPID STORAGE; MACROPHAGE; NUCLEOTIDE SEQUENCE; PHAGOCYTE; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; SIGNAL TRANSDUCTION;

APOPTOSIS; ATP-BINDING CASSETTE TRANSPORTERS; CELL LINE; CHOLESTEROL; CYTOKINES; HUMANS; INFLAMMATION; INTERLEUKIN-6; JURKAT CELLS; LIPOPROTEINS; MACROPHAGES; MONOCYTES; PHAGOCYTOSIS; PHENOTYPE; RNA INTERFERENCE;

EID: 80052213433     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.264325     Document Type: Article

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