Monocyte chemoattractant protein-1 induces endothelial cell apoptosis in vitro through a p53-dependent mitochondrial pathway

Acta Biochimica et Biophysica Sinica

Volumn 43, Issue 10, 2011, Pages 787-795

  Zhang, Xuan ^a   Liu, Xiping ^a   Shang, Huifeng ^a   Xu, Yan ^a   Qian, Minzhang ^a  

^a ZUNYI MEDICAL UNIVERSITY   (China)

Author keywords

apoptosis; endothelial cell; MCP 1

Indexed keywords

MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN P53;

APOPTOSIS; ARTICLE; ATHEROSCLEROSIS; CELL CULTURE; CYTOLOGY; GENE EXPRESSION REGULATION; HUMAN; METABOLISM; MITOCHONDRION; PATHOLOGY; SIGNAL TRANSDUCTION; UMBILICAL VEIN; UPREGULATION; VASCULAR ENDOTHELIUM;

APOPTOSIS; ATHEROSCLEROSIS; CELLS, CULTURED; CHEMOKINE CCL2; ENDOTHELIUM, VASCULAR; GENE EXPRESSION REGULATION; HUMANS; MITOCHONDRIA; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53; UMBILICAL VEINS; UP-REGULATION;

EID: 80053499753     PISSN: 16729145     EISSN: 17457270     Source Type: Journal    
DOI: 10.1093/abbs/gmr072     Document Type: Article

References (50)

1. Allen SJ, Crown SE and Handel TM. Chemokine: Receptor structure, interactions, and antagonism. Annu Rev Immunol 2007, 25: 787-820. (Pubitemid 46697924)
2. Charo IF and Ransohoff RM. The many roles of chemokines and chemokine receptors in inflammation. N Engl J Med 2006, 354: 610-621. (Pubitemid 43209108)
3. Niu J and Kolattukudy PE. Role of MCP-1 in cardiovascular disease: Molecular mechanisms and clinical implications. Clin Sci (Lond) 2009, 117: 95-109.
4. Gosling J, Slaymaker S, Gu L, Tseng S, Zlot CH, Young SG and Rollins BJ, et al. MCP-1 deficiency reduces susceptibility to atherosclerosis in mice that overexpress human apolipoprotein B. J Clin Invest 1999, 103: 773-778. (Pubitemid 29152622)
5. Boring L, Gosling J, Cleary M and Charo IF. Decreased lesion formation in CCR2-/- mice reveals a role for chemokines in the initiation of atherosclerosis. Nature 1998, 394: 894-897. (Pubitemid 28410911)
6. Pasceri V, Chang J, Willerson JT and Yeh ET. Modulation of C-reactive protein-mediated monocyte chemoattractant protein-1 induction in human endothelial cells by anti-atherosclerosis drugs. Circulation 2001, 103: 2531-2534. (Pubitemid 32521959)
7. Pober JS and Sessa WC. Evolving functions of endothelial cells in inflammation. Nat Rev Immunol 2007, 7: 803-815. (Pubitemid 47480307)
8. Stoneman VE and Bennett MR. Role of apoptosis in atherosclerosis and its therapeutic implications. Clin Sci (Lond) 2004, 107: 343-354. (Pubitemid 39389301)
9. Dimmeler S, Hermann C and Zeiher AM. Apoptosis of endothelial cells. Contribution to the pathophysiology of atherosclerosis? Eur Cytokine Netw 1998, 9: 697-698. (Pubitemid 29033942)
10. Choy JC, Granville DJ, Hunt DW and McManus BM. Endothelial cell apoptosis: Biochemical characteristics and potential implications for atherosclerosis. J Mol Cell Cardiol 2001, 33: 1673-1690. (Pubitemid 32844225)
11. Tricot O, Mallat Z, Heymes C, Belmin J, Leseche G and Tedgui A. Relation between endothelial cell apoptosis and blood flow direction in human atherosclerotic plaques. Circulation 2000, 101: 2450-2453. (Pubitemid 30366245)
12. Ido Y, Carling D and Ruderman N. Hyperglycemia-induced apoptosis in human umbilical vein endothelial cells: Inhibition by the AMP-activated protein kinase activation. Diabetes 2002, 51: 159-167. (Pubitemid 34517993)
13. Cheng C, Tempel D, van Haperen R, van der Baan A, Grosveld F, Daemen MJ and Krams R, et al. Atherosclerotic lesion size and vulnerability are determined by patterns of fluid shear stress. Circulation 2006, 113: 2744-2753. (Pubitemid 43947992)
14. Bansilal S, Farkouh ME and Fuster V. Role of insulin resistance and hyperglycemia in the development of atherosclerosis. Am J Cardiol 2007, 99: 6B-14B.
15. Li QS, Liu Y, Feng ZJ, Zhang YL and Qian MZ. Monocyte chemotactic protein-1 induces the apoptosis of human umbilical vein endothelial cells. Acta Academiae Medicinae Militaris Tertiae 2007, 29: 1682-1684.
16. Li QS, Liu Y, Feng ZJ, Lu ZS and Qian MZ. The molecular mechanism of apoptosis of human umbilical vein endothelial cells induced by monocyte chemotacitic protein-1. Sheng Li Xue Bao 2010, 62: 63-68.
17. Xu Y, Liu XP, Li QS, Shang HF and Qian MZ. CCR2 mediates monocyte chemotactic protein-1 induced apoptosis in human vein endothelial cells. Chin J Biochem Mol Biol 2010, 26: 356-361.
18. Liu D, Cheng T, Guo H, Fernández JA, Griffin JH, Song X and Zlokovic BV. Tissue plasminogen activator neurovascular toxicity is controlled by activated protein C. Nat Med 2004, 10: 1379-1383. (Pubitemid 40022721)
19. Abramov AY, Smulders-Srinivasan TK, Kirby DM, Acin-Perez R, Enriquez JA, Lightowlers RN and Duchen MR, et al. Mechanism of neurodegeneration of neurons with mitochondrial DNA mutations. Brain 2010, 133: 797-807.
20. Morán M, Rivera H, Sánchez-Aragó M, Blázquez A, Merinero B, Ugalde C and Arenas J, et al. Mitochondrial bioenergetics and dynamics interplay in complex I-deficient fibroblasts. Biochim Biophys Acta 2010, 1802: 443-453.
21. Espino J, Mediero M, Lozano GM, Bejarano I, Ortiz, García JF and Pariente JA, et al. Reduced levels of intracellular calcium releasing in spermatozoa from asthenozoospermic patients. Reprod Biol Endocrinol 2009, 7: 11.
22. de Lemos JA, Morrow DA, Sabatine MS, Murphy SA, Gibson CM, Antman EM and McCabe CH, et al. Association between plasma levels of monocyte chemoattractant protein-1 and long-term clinical outcomes in patients with acute coronary syndromes. Circulation 2003, 107: 690-695. (Pubitemid 36222595)
23. Deo R, Khera A, McGuire DK, Murphy SA, Meo NJP, Morrow DA and de Lemos JA. Association among plasma levels of monocyte chemoattractant protein-1, traditional cardiovascular risk factors, and subclinical atherosclerosis. J Am Coll Cardiol 2004, 44: 1812-1818. (Pubitemid 39424080)
24. Rollins BJ, Walz A and Baggiolini M. Recombinant human MCP-1/JE induces chemotaxis, calcium flux, and the respiratory burst in human monocytes. Blood 1991, 78: 1112-1116.
25. Green DR and Reed JC. Mitochondria and apoptosis. Science 1998, 281: 1309-1312. (Pubitemid 28406816)
26. Wang X. The expanding role of mitochondria in apoptosis. Genes Dev 2001, 15: 2922-2933. (Pubitemid 33078942)
27. Marchenko ND, Zaika A and Moll UM. Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling. J Biol Chem 2000, 275: 16202-16212. (Pubitemid 30366932)
28. Schuler M and Green DR. Mechanisms of p53-dependent apoptosis. Biochem Soc Trans 2001, 29: 684-688. (Pubitemid 33131760)
29. Mihara M, Erster S, Zaika A, Petrenko O, Chittenden T, Pancoska P and Moll UM. p53 has a direct apoptogenic role at the mitochondria. Mol Cell 2003, 11: 577-590. (Pubitemid 36385115)
30. Lorenzo E, Ruiz-Ruiz C, Quesada AJ, Hernández G, Rodríguez A, López-Rivas A and Redondo JM. Doxorubicin induces apoptosis and CD95 gene expression in human primary endothelial cells through a p53-dependent mechanism. J Biol Chem 2002, 277: 10883-10892. (Pubitemid 34952843)
31. Reyland ME. Protein kinase C and apoptosis. In: Srivastava R ed. Apoptosis, Cell Signaling, and Human Diseases. Totowa, NJ: Humana Press, 2007, 31-55.
32. Khalil RA. Protein kinase C. In: Khalil RA eds. Regulation of Vascular Smooth Muscle Function. San Rafael, CA: Morgan & Claypool Life Sciences, 2010, 21-30.
33. Kock K, Koenen A, Giese B, Fraunholz M, May K, Siegmund W and Hammer E, et al. Rapid modulation of the organic anion transporting polypeptide 2B1 (OATP2B1, SLCO2B1) function by protein kinase C-mediated internalization. J Biol Chem 2010, 285: 11336-11347.
34. Jiang H, Cheng D, Liu W, Peng J and Feng J. Protein kinase C inhibits autophagy and phosphorylates LC3. Biochem Biophys Res Commun 2010, 395: 471-476.
35. Moench I, Prentice H, Rickaway Z and Weissbach H. Sulindac confers high level ischemic protection to the heart through late preconditioning mechanisms. Proc Natl Acad Sci USA 2009, 106: 19611-19616.
36. Hains AB, Vu MA, Maciejewski PK, van Dyck CH, Gottron M and Arnsten AF. Inhibition of protein kinase C signaling protects prefrontal cortex dendritic spines and cognition from the effects of chronic stress. Proc Natl Acad Sci USA 2009, 106: 17957-17962.
37. Rafiee P, Nelson VM, Manley S, Wellner M, Floer M, Binion DG and Shaker R. Effect of curcumin on acidic pH-induced expression of IL-6 and IL-8 in human esophageal epithelial cells (HET-1A): Role of PKC, MAPKs, and NF-kappaB. Am J Physiol Gastrointest Liver Physiol 2009, 296: G388-398.
38. Herbert JM, Augereau JM, Gleye J and Maffrand JP. Chelerythrine is a potent and specific inhibitor of protein kinase C. Biochem Biophys Res Commun 1990, 172: 993-999.
39. Niu J, Azfer A, Zhelyabovska O, Fatma S and Kolattukudy PE. Monocyte chemotactic protein (MCP)-1 promotes angiogenesis via a novel transcription factor, MCP-1-induced protein (MCPIP). J Biol Chem 2008, 283: 14542-14551.
40. Charo IF. Monocyte-endothelial cell interactions. Curr Opin Lipidol 1992, 3: 335-343.
41. Hesselgesser J, Taub D, Baskar P, Greenberg M, Hoxie J, Kolson D and Horuk R. Neuronal apoptosis induced by HIV-1 gp120 and the chemokine SDF-1 alpha is mediated by the chemokine receptor CXCR4. Curr Biol 1998, 8: 595-598. (Pubitemid 28222895)
42. Herbein G, Mahlknecht U, Batliwalla F, Gregersen P, Pappas T, Butler J and O'Brien W, et al. Apoptosis of CD8+ T cells is mediated by macrophages through interaction of HIV gp120 with chemokine receptor CXCR4. Nature 1998, 395: 189-194. (Pubitemid 28425660)
43. Mellado M, de Ana A, Moreno M, Martínez C and Rodríguez- Frade JM. A potential immune escape mechanism by melanoma cells through the activation of chemokine-induced T cell death. Curr Biol 2001, 11: 691-696. (Pubitemid 32418165)
44. Glaser J, Gonzalez R, Sadr E and Keirstead HS. Neutralization of the chemokine CXCL10 reduces apoptosis and increases axon sprouting after spinal cord injury. J Neurosci Res 2006, 84: 724-734. (Pubitemid 44366674)
45. Dimmeler S and Zeiher AM. Endothelial cell apoptosis in angiogenesis and vessel regression. Circ Res 2000, 87: 434-439.
46. Brooks PC, Montgomery AM, Rosenfeld M, Reisfeld RA, Hu T, Klier G and Cheresh DA. Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell 1994, 79: 1157-1164.
47. Papapetropoulos A, Fulton D, Mahboubi K, Kalb RG, O'Connor DS, Li F and Altieri DC, et al. Angiopoietin-1 inhibits endothelial cell apoptosis via the Akt/survivin pathway. J Biol Chem 2000, 275: 9102-9105. (Pubitemid 30185122)
48. Hong KH, Ryu J and Han KH. Monocyte chemoattractant protein-1-induced angiogenesis is mediated by vascular endothelial growth factor-A. Blood 2005, 105: 1405-1407. (Pubitemid 40223654)
49. Salcedo R, Ponce ML, Young HA, Wasserman K, Ward JM, Kleinman HK and Oppenheim JJ, et al. Human endothelial cells express CCR2 and respond to MCP-1: Direct role of MCP-1 in angiogenesis and tumor progression. Blood 2000, 96: 34-40. (Pubitemid 30456447)
50. Zhou L, Azfer A, Niu J, Graham S, Choudhury M, Adamski FM and Younce C, et al. Monocyte chemoattractant protein-1 induces a novel transcription factor that causes cardiac myocyte apoptosis and ventricular dysfunction. Circ Res 2006, 98: 1177-1185. (Pubitemid 43948104)