High-density lipoprotein transport through aortic endothelial cells involves scavenger receptor BI and ATP-binding cassette transporter G1

Circulation Research

Volumn 104, Issue 10, 2009, Pages 1142-1150

  Rohrer, Lucia ^a   Ohnsorg, Pascale M ^a   Lehner, Marc ^a   Landolt, Franziska ^a   Rinninger, Franz ^b   Von Eckardstein, Arnold ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

Cholesterol homeostasis; Endothelial cells; Lipoproteins; Vascular endothelial function; Vascular permeability

Indexed keywords

ABC TRANSPORTER G1; HIGH DENSITY LIPOPROTEIN; INULIN; SCAVENGER RECEPTOR BI; ABC TRANSPORTER; CD36 ANTIGEN; CHOLESTEROL;

AORTA; ARTICLE; BIOTINYLATION; CELL COMPARTMENTALIZATION; CELL INTERACTION; CELL MATURATION; CELL MEMBRANE PERMEABILITY; CELL SURFACE; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE MICROSCOPY; INTERNALIZATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; RNA INTERFERENCE; TEMPERATURE DEPENDENCE; TRANSCYTOSIS; VASCULAR ENDOTHELIUM; ANIMAL; CATTLE; CELL CULTURE; CYTOLOGY; METABOLISM; PHYSIOLOGY; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; ANTIGENS, CD36; AORTA; ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL TRANSPORT; CATTLE; CELL MEMBRANE PERMEABILITY; CELLS, CULTURED; CHOLESTEROL; ENDOTHELIUM, VASCULAR; LIPOPROTEINS, HDL;

EID: 66949145819     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.108.190587     Document Type: Article

References (35)

1. Curtiss LK, Valenta DT, Hime NJ, Rye KA. What is so special about apolipoprotein AI in reverse cholesterol transport? Arterioscler Thromb Vasc Biol. 2006;26:12-19.
2. Gordon DJ, Rifkind BM. High-density lipoprotein-the clinical implications of recent studies. N Engl J Med. 1989;321:1311-1316.
3. Tall AR, Yvan-Charvet L, Terasaka N, Pagler T, Wang N. HDL, ABC transporters, and cholesterol efflux: implications for the treatment of atherosclerosis. Cell Metab. 2008;7:365-375.
4. Rader DJ. Molecular regulation of HDL metabolism and function: implications for novel therapies. J Clin Invest. 2006;116:3090-3100.
5. Von Eckardstein A, Rohrer L. Transendothelial lipoprotein transport and regulation of endothelial permeability and integrity by lipoproteins. Curr Opin Lipidol. In press.
6. Vandenbroucke E, Mehta D, Minshall R, Malik AB. Regulation of en-dothelial junctional permeability. Ann N Y Acad Sci. 2008;1123:134-145.
7. Minshall RD, Malik AB. Transport across the endothelium: regulation of endothelial permeability. Handb Exp Pharmacol. 2006(176 p t 1):107-144
8. Minshall RD, Tiruppathi C, Vogel SM, Malik AB. Vesicle formation and trafficking in endothelial cells and regulation of endothelial barrier function. Histochem Cell Biol. 2002;117:105-112.
9. Cavelier C, Rohrer L, von Eckardstein A. ATP-Binding cassette transporter A1 modulates apolipoprotein A-I transcytosis through aortic en-dothelial cells. Circ Res. 2006;99:1060-1066.
10. Rohrer L, Cavelier C, Fuchs S, Schluter MA, Volker W, von Eckardstein A. Binding, internalization and transport of apolipoprotein A-I by vascular endothelial cells. Biochim Biophys Acta. 2006;1761:186-194.
11. Freeman M, Ekkel Y, Rohrer L, Penman M, Freedman NJ, Chisolm GM, Krieger M. Expression of type I and type II bovine scavenger receptors in Chinese hamster ovary cells: lipid droplet accumulation and nonre-ciprocal cross competition by acetylated and oxidized low density lipoprotein. Proc Natl Acad Sci U S A. 1991;88:4931-4935.
12. Kunitake ST, Mendel CM, Hennessy LK. Interconversion between apo-lipoprotein A-I-containing lipoproteins of pre-beta and alpha electro-phoretic mobilities. J Lipid Res. 1992;33:1807-1816.
13. Liang HQ, Rye KA, Barter PJ. Cycling of apolipoprotein A-I between lipid-associated and lipid-free pools. Biochim Biophys Acta. 1995;1257: 31-37.
14. Liang HQ, Rye KA, Barter PJ. Dissociation of lipid-free apolipoprotein A-I from high density lipoproteins. J Lipid Res. 1994;35:1187-1199.
15. Lorenzi I, von Eckardstein A, Radosavljevic S, Rohrer L. Lipidation of apolipoprotein A-I by ATP-binding cassette transporter (ABC) A1 generates an interaction partner for ABCG1 but not for scavenger receptor BI. Biochim Biophys Acta. 2008;1781:306-313.
16. Lorenzi I, von Eckardstein A, Cavelier C, Radosavljevic S, Rohrer L. Apolipoprotein A-I but not high-density lipoproteins are internalised by RAW macrophages: roles of ATP-binding cassette transporter A1 and scavenger receptor BI. J Mol Med. 2008;86:171-183.
17. von Eckardstein A, Hersberger M, Rohrer L. Current understanding of the metabolism and biological actions of HDL. Curr Opin Clin Nutr Metab Care. 2005;8:147-152.
18. Mineo C, Deguchi H, Griffin JH, Shaul PW. Endothelial and anti-thrombotic actions of HDL. Circ Res. 2006;98:1352-1364.
19. Zannis VI, Chroni A, Krieger M. Role of apoA-I, ABCA1, LCAT, and SR-BI in the biogenesis of HDL. J Mol Med. 2006;84:276-294.
20. Davidson WS, Thompson TB. The structure of apolipoprotein A-I in high density lipoproteins. J Biol Chem. 2007;282:22249-22253.
21. Krieger M. Charting the fate of the "good cholesterol": identification and characterization of the high-density lipoprotein receptor SR-BI. Annu Rev Biochem. 1999;68:523-558.
22. Wüstner D. Mathematical analysis of hepatic high density lipoprotein transport based on quantitative imaging data. J Biol Chem. 2005;280: 6766-6779.
23. Hatzopoulos AK, Rigotti A, Rosenberg RD, Krieger M. Temporal and spatial pattern of expression of the HDL receptor SR-BI during murine embryogenesis. J Lipid Res. 1998;39:495-508.
24. Brewer HB Jr, Remaley AT, Neufeld EB, Basso F, Joyce C. Regulation of plasma high-density lipoprotein levels by the ABCA1 transporter and the emerging role of high-density lipoprotein in the treatment of cardiovascular disease. Arterioscler Thromb Vasc Biol. 2004;24:1755-1760.
25. Hoekstra M, Kruijt JK, Van Eck M, Van Berkel TJ. Specific gene expression of ATP-binding cassette transporters and nuclear hormone receptors in rat liver parenchymal, endothelial, and Kupffer cells. J Biol Chem. 2003;278:25448-25453.
26. Terasaka N, Yu S, Yvan-Charvet L, Wang N, Mzhavia N, Langlois R, Pagler T, Li R, Welch CL, Goldberg IJ, Tall AR. ABCG1 and HDL protect against endothelial dysfunction in mice fed a high-cholesterol diet. J Clin Invest. 2008;118:3701-3713.
27. Acton S, Rigotti A, Landschulz KT, Xu S, Hobbs HH, Krieger M. Identification of scavenger receptor SR-BI as a high density lipoprotein receptor. Science. 1996;271:518-520.
28. Eckhardt ER, Cai L, Shetty S, Zhao Z, Szanto A, Webb NR, Van der Westhuyzen DR. High density lipoprotein endocytosis by scavenger receptor SR-BII is clathrin-dependent and requires a carboxyl-terminal dileucine motif receptor SR-BII is clathrin-dependent and requires a carboxyl-terminal dileucine motif. J Biol Chem. 2006;281:4348-4353.
29. Mineo C, Shaul PW. Role of high-density lipoprotein and scavenger receptor B type I in the promotion of endothelial repair. Trends Car-diovasc Med. 2007;17:156-161.
30. Argraves KM, Gazzolo PJ, Groh EM, Wilkerson BA, Matsuura BS, Twal WO, Hammad SM, Argraves WS. High density lipoprotein-associated sphingosine 1-phosphate promotes endothelial barrier function. J Biol Chem. 2008;283:25074-25081.
31. Argraves KM, Argraves WS. HDL serves as a S1P signaling platform mediating a multitude of cardiovascular effects. J Lipid Res. 2007;48: 2325-2333.
32. Komarova YA, Mehta D, Malik AB. Dual regulation of endothelial junctional permeability. Sci STKE. 2007;2007:re8.
33. Mehta D, Malik AB. Signaling mechanisms regulating endothelial permeability. Physiol Rev. 2006;86:279-367.
34. Abdulla J, Haarbo J, Kober L, Torp-Pedersen C. Impact of implantable defibrillators and resynchronization therapy on outcome in patients with left ventricular dysfunction-a meta-analysis. Cardiology. 2006;106: 249-255.
35. Zhu W, Saddar S, Seetharam D, Chambliss KL, Longoria C, Silver DL, Yuhanna IS, Shaul PW, Mineo C. The scavenger receptor class B type I adaptor protein PDZK1 maintains endothelial monolayer integrity. Circ Res. 2008;102:480-487.