Antibodies against high-density lipoprotein binding proteins enhance high-density lipoprotein uptake but do not affect cholesterol efflux from rat hepatoma cells

International Journal of Biochemistry and Cell Biology

Volumn 29, Issue 4, 1997, Pages 583-588

  Sviridov, Dmitri ^a   Sasahara, Takayuki ^a   Pyle, Louise E ^a   Nestel, Paul J ^a   Fidge, Noel H ^a  

^a BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

Author keywords

Antibody; Cholesterol biosynthesis; Cholesterol efflux; Hepatoma cells; High density lipoprotein receptor

Indexed keywords

APOLIPOPROTEIN A1; HIGH DENSITY LIPOPROTEIN; HIGH DENSITY LIPOPROTEIN RECEPTOR; PROTEIN ANTIBODY;

ANIMAL CELL; ARTICLE; CELL CULTURE; CHOLESTEROL SYNTHESIS; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; HEPATOMA CELL; IN VITRO STUDY; LIPOPROTEIN METABOLISM; NONHUMAN; RAT;

ANIMALS; ANTIBODIES; BIOLOGICAL TRANSPORT; CARRIER PROTEINS; CHOLESTEROL; HUMANS; LIPOPROTEINS, HDL; LIVER NEOPLASMS, EXPERIMENTAL; MEMBRANE PROTEINS; RABBITS; RATS; RECEPTORS, LIPOPROTEIN; RNA-BINDING PROTEINS; TUMOR CELLS, CULTURED;

EID: 0030919236     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1357-2725(96)00174-4     Document Type: Article

References (23)

1. Barter P. (1993) High-density lipoproteins and reverse cholesterol transport. Curr. Opin. Lipidol. 4, 210-217.
2. Bjorck P.. Braesch-Andersen S. and Paulie S. (1994) Antibodies to distinct epitopes on the CD40 molecule co-operate in stimulation and can be used for the detection of soluble CD40. Immunology 83, 430-437.
3. Bradford M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-256.
4. Cohn J. S., Fidge N. F. and Nestel P. J. (1985) Initial plasma high-density lipoprotein distribution in the rat: effects of age, sex and fasting. Am. J. Physisol. 249, G369-G376.
5. DeLamatre J. G., Sarphie T. G., Archibold R. C. and Hornick C. A. (1990) Metabolism of apoE-free high-density lipoproteins in rat hepatoma cells: evidence for a retroendocytic pathway. J. Lipid Res. 31, 191-202.
6. Fielding C. J. and Fielding P. E. (1995) Molecular physiology of the reverse cholesterol transport. J. Lipid Res. 36, 211-228.
7. Francis G. A., Knopp R. H. and Oram J. F. (1995) Defective removal of cellular cholesterol and phospholipids by apolipoprotein A-I in Tangier disease. J. Clin. Invest. 96, 78-87.
8. Havel R. J., Eder H. A. and Bragdon J. H. (1955) The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum. J. Biol. Chem. 34, 1345-1353.
9. Hidaka H. and Fidge N. H. (1992) Affinity purification of the hepatic high-density lipoprotein receptor identifies two acidic glycoproteins and enables further characterization of their binding properties. Biochem. J. 284, 161-167.
10. Holvoet P., Perez G., Bernar H., Brouwers E., Vanloo B., Rosseneu M. and Collen D. (1994) Stimulation with monoclonal antibody (mAb4E4) of scavenger receptor-mediated uptake of chemically modified low density lipoproteins by THP-1-derived macrophages enhances foam cell generation. J. Clin. Invest. 93, 89-98.
11. Kagami A., Fidge N. H. and Nestel P. J. (1985) Specific binding of high-density lipoprotein (HDL3) is not related to sterol synthesis in rat intestinal mucosa. J. Lipid Res. 26, 705-712.
12. Kambouris A. M., Roach P. D., Calvert G. D. and Nestel P. J. (1990) Retroendocytosis of high-density lipoproteins by the human hepatoma cell line, HepG2. Arteriosclerosis 10, 582-590.
13. Koelz H. R., Sherrill B. C., Turley S. D. and Dietschy J. M. (1982) Correlation of low and high-density lipoprotein binding in vivo with rates of lipoprotein degradation in the rat. J. Biol. Chem. 257, 8061-8072.
14. Lutton C. and Fidge N. (1994) Distribution of high-density lipoprotein binding proteins among various tissues in the rat. C.R. Acad. Sci. Paris Sci. Life Sci. 317, 731-735.
15. Massart S., Maiter D., Portetelle D., Adam E., Renaville R. and Ketelslegers J. M. (1993) Monoclonal antibodies to bovine growth hormone potentiate hormonal activity in vivo by enhancing growth hormone binding to hepatic somatogenic receptors. J. Endocrinol. 139, 383-393.
16. Mathai D., Fidge N., Tozuka M. and Mitchell A. (1990) Regulation of hepatic high-density lipoprotein binding proteins after administration of simvastatin and cholestyramine to rats. Arteriosclerosis 10, 1045-1050.
17. Sasahara T., Kobori S., Kasho M., Sato Y., Nishikawa T., Yano T., Takeda H. and Shichiri M. (1994) The metabolic fate of apolipoprotein A-I-containing lipoproteins internalized into HepG2 cells: resecreted lipoproteins as a potent inducer for cholesterol efflux. Atherosclerosis 106, 179-190.
18. Sviridov D. and Fidge N. (1995a) Efflux of intracellular vs plasma membrane cholesterol in HepG2 cells: different availability and regulation by apolipoprotein A-I. J. Lipid Res. 36, 1887-1896.
19. Sviridov D. and Fidge N. (1995b) Pathway of cholesterol efflux from human hepatoma cells. Biochim. Biophys. Acta 1256, 210-230.
20. Sviridov D. D., Ehnholm C., Tenkanen H., Pavlov M. Y., Safonova I. G. and Repin V. S. (1992) Studies on the proteins involved in the interaction of high-density lipoprotein with isolated human small intestine epithelial cells. FEBS Lett. 303, 202-204.
21. Sviridov D. D., Safonova I. G., Gusev V. A., Talalaev A. G., Tsibulsky V. P., Ivanov V. O., Preobrazensky S. N., Repin V. S. and Smirnov V. N. (1986) Specific high affinity binding and degradation of high-density lipoproteins by isolated epithelial cells of human small intestine. Metabolism 35, 588-595.
22. Towbin H., Staehelin T. and Gordon J. (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl Acad. Sci. U.S.A. 76, 4350-4354.
23. Tozuka M. and Fidge N. (1989) Purification and characterization of two high-density lipoprotein-binding proteins from rat and human liver. Biochem. J. 261, 239-244.