Solubilization and formulation of chrysosplenol C in solid dispersion with hydrophilic carriers

International Journal of Pharmaceutics

Volumn 512, Issue 1, 2016, Pages 314-321

  Ng, Choon Lian ^a   Lee, Sang Eun ^a   Lee, Joon Kyung ^a   Kim, Tae Hyeon ^a   Jang, Woo Suk ^a   Choi, Jin Seok ^a   Kim, Young Ho ^a   Kim, Jin Ki ^b   Park, Jeong Sook ^a  

^a Chungnam National University   (South Korea)

^b Hanyang University   (South Korea)

Author keywords

Chrysosplenol C; Dissolution; Hydrophilic carrier; Solid dispersion

Indexed keywords

CHRYSOSPLENOL C; DISTILLED WATER; DODECYL SULFATE SODIUM; FLAVONE DERIVATIVE; MACROGOL 6000; POVIDONE; SURFACTANT; UNCLASSIFIED DRUG; DRUG CARRIER; FLAVONOID; MACROGOL DERIVATIVE; POLY(N-VINYLPYRROLIDINE); POLYVINYL DERIVATIVE; POWDER; PYRROLIDINE DERIVATIVE;

ARTICLE; CACO 2 CELL LINE; CELL VIABILITY; CONTROLLED STUDY; DISPERSION; DISSOLUTION; DRUG BIOAVAILABILITY; DRUG FORMULATION; DRUG RELEASE; DRUG SAFETY; DRUG SOLUBILITY; HYDROPHILICITY; IN VITRO STUDY; PRIORITY JOURNAL; PROCESS OPTIMIZATION; SOLID; CELL SURVIVAL; CHEMICAL PHENOMENA; CHEMISTRY; DRUG EFFECTS; HUMAN; POWDER; PROCEDURES; SOLUBILITY; TUMOR CELL LINE;

CELL LINE, TUMOR; CELL SURVIVAL; DRUG CARRIERS; DRUG COMPOUNDING; DRUG LIBERATION; FLAVONOIDS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; POLYETHYLENE GLYCOLS; POLYVINYLS; POWDERS; PYRROLIDINES; SOLUBILITY; SURFACE-ACTIVE AGENTS;

EID: 84984962748     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2016.08.062     Document Type: Article

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