Preparation, characterization and in vivo evaluation of ibuprofen binary solid dispersions with poloxamer 188

International Journal of Pharmaceutics

Volumn 343, Issue 1-2, 2007, Pages 228-237

  Newa, Madhuri ^a   Bhandari, Krishna Hari ^a   Li, Dong Xun ^a   Kwon, Tae Hyub ^a   Kim, Jung Ae ^a   Yoo, Bong Kyu ^a   Woo, Jong Soo ^b   Lyoo, Won Seok ^a   Yong, Chul Soon ^a   Choi, Han Gon ^a  

^a Yeungnam University   (South Korea)

^b Hanmi Pharmaceutical Co Ltd   (South Korea)

Author keywords

Bioavailability; Dissolution; Ibuprofen; Poloxamer 188; Solid dispersion; Solubility

Indexed keywords

IBUPROFEN; POLOXAMER;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG ELIMINATION; DRUG HALF LIFE; DRUG RELEASE; DRUG SCREENING; DRUG SOLUBILITY; DRUG SYNTHESIS; INFRARED SPECTROSCOPY; MAXIMUM PLASMA CONCENTRATION; MELTING POINT; NONHUMAN; PRIORITY JOURNAL; RAT; SCANNING ELECTRON MICROSCOPY;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BIOLOGICAL AVAILABILITY; CALORIMETRY, DIFFERENTIAL SCANNING; DRUG COMPOUNDING; EXCIPIENTS; IBUPROFEN; MICROSCOPY, ELECTRON, SCANNING; POLOXAMER; RATS; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

EID: 34548270616     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2007.05.031     Document Type: Article

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