HPMC as a potential enhancer of nimodipine biopharmaceutical properties via ball-milled solid dispersions

Carbohydrate Polymers

Volumn 99, Issue , 2014, Pages 474-482

  Riekes, Manoela Klüppel ^a   Kuminek, Gislaine ^a   Rauber, Gabriela Schneider ^a   De Campos, Carlos Eduardo Maduro ^a   Bortoluzzi, Adailton João ^a   Stulzer, Hellen Karine ^a  

^a FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

Author keywords

Biopharmaceutical properties; HPMC; Nimodipine; Solid dispersion

Indexed keywords

AMORPHOUS SOLID DISPERSIONS; BIOPHARMACEUTICAL PROPERTIES; CALCIUM CHANNEL BLOCKERS; DIFFERENT PROPORTIONS; FORMULATION DEVELOPMENT; HPMC; NIMODIPINE; SOLID DISPERSION;

CARBOXYLIC ACIDS; PYRIDINE; SOLUBILITY;

DISPERSIONS;

ANTIHYPERTENSIVE AGENT; DRUG DERIVATIVE; HYDROXYPROPYLMETHYLCELLULOSE; METHYLCELLULOSE; NIMODIPINE; WATER;

ARTICLE; BIOPHARMACEUTICAL PROPERTIES; CHEMISTRY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG STABILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HPMC; INFRARED SPECTROSCOPY; POWDER; SOLID DISPERSION; SOLUBILITY;

BIOPHARMACEUTICAL PROPERTIES; HPMC; NIMODIPINE; SOLID DISPERSION;

ANTIHYPERTENSIVE AGENTS; CALORIMETRY, DIFFERENTIAL SCANNING; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; METHYLCELLULOSE; NIMODIPINE; POWDERS; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; WATER;

EID: 84884184043     PISSN: 01448617     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.carbpol.2013.08.046     Document Type: Article

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