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Volumn 511, Issue 1, 2016, Pages 359-366

Dendrimers as a promising tool in ocular therapeutics: Latest advances and perspectives

Author keywords

Complexation; Dendrimers; Encapsulation; Safety; Targeting; Transfectants

Indexed keywords

AGENTS ACTING ON THE EYE; DENDRIMER; POLYAMIDOAMINE; DRUG; DRUG CARRIER;

EID: 84984889756     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2016.07.031     Document Type: Short Survey
Times cited : (47)

References (50)
  • 1
    • 84934898243 scopus 로고    scopus 로고
    • Novel biodegradable polyesteramide microspheres for controlled drug delivery in Ophthalmology
    • Andres-Guerrero, V., Zong, M., et al. Novel biodegradable polyesteramide microspheres for controlled drug delivery in Ophthalmology. J. Control. Release 211 (2015), 105–117.
    • (2015) J. Control. Release , vol.211 , pp. 105-117
    • Andres-Guerrero, V.1    Zong, M.2
  • 3
    • 84871918550 scopus 로고    scopus 로고
    • The possible Proton Sponge Effect of Polyethylenimine (PEI) does not include change in lysosomal pH
    • Benjaminsen, R.V., Mattebjerg, M.A., et al. The possible Proton Sponge Effect of Polyethylenimine (PEI) does not include change in lysosomal pH. Mol. Ther. 21:1 (2013), 149–157.
    • (2013) Mol. Ther. , vol.21 , Issue.1 , pp. 149-157
    • Benjaminsen, R.V.1    Mattebjerg, M.A.2
  • 4
    • 84864444446 scopus 로고    scopus 로고
    • Interfacial interaction between transmembrane ocular mucins and adhesive polymers and dendrimers analyzed by surface plasmon resonance
    • Bravo-Osuna, I., Noiray, M., et al. Interfacial interaction between transmembrane ocular mucins and adhesive polymers and dendrimers analyzed by surface plasmon resonance. Pharm. Res. 29:8 (2012), 2329–2340.
    • (2012) Pharm. Res. , vol.29 , Issue.8 , pp. 2329-2340
    • Bravo-Osuna, I.1    Noiray, M.2
  • 5
    • 84984917130 scopus 로고    scopus 로고
    • Novel water-soluble mucoadhesive carbosilane dendrimers for ocular administration
    • Bravo-Osuna, I., Vicario-de-la-Torre, M., et al. Novel water-soluble mucoadhesive carbosilane dendrimers for ocular administration. Mol. Pharm., 2016, 10.1021/acs.molpharmaceut.6b00182.
    • (2016) Mol. Pharm.
    • Bravo-Osuna, I.1    Vicario-de-la-Torre, M.2
  • 6
    • 84989581991 scopus 로고
    • ‘Cascade’- and ‘Nonskid-Chain-like’ syntheses of molecular cavity topologies
    • Buhleier, E., et al. ‘Cascade’- and ‘Nonskid-Chain-like’ syntheses of molecular cavity topologies. Synthesis 2 (1978), 155–158.
    • (1978) Synthesis , vol.2 , pp. 155-158
    • Buhleier, E.1
  • 7
    • 79953329178 scopus 로고    scopus 로고
    • Long-term benefit of sustained-delivery fluocinolone acetonide vitreous inserts for diabetic Macular Edema
    • e622
    • Campochiaro, P.A., Brown, D.M., et al. Long-term benefit of sustained-delivery fluocinolone acetonide vitreous inserts for diabetic Macular Edema. Ophthalmology 118:4 (2011), 626–635 e622.
    • (2011) Ophthalmology , vol.118 , Issue.4 , pp. 626-635
    • Campochiaro, P.A.1    Brown, D.M.2
  • 8
    • 0034801575 scopus 로고    scopus 로고
    • Synthesis and characterization of polyether-ester dendrimers from glycerol and lactic acid
    • Carnahan, M.A., Grinstaff, M.W., Synthesis and characterization of polyether-ester dendrimers from glycerol and lactic acid. J. Am. Chem. Soc. 123:12 (2001), 2905–2906.
    • (2001) J. Am. Chem. Soc. , vol.123 , Issue.12 , pp. 2905-2906
    • Carnahan, M.A.1    Grinstaff, M.W.2
  • 9
    • 0037093837 scopus 로고    scopus 로고
    • Hybrid dendritic-linear polyester-ethers for in situ photopolymerization
    • Carnahan, M.A., Middleton, C., et al. Hybrid dendritic-linear polyester-ethers for in situ photopolymerization. J. Am. Chem. Soc. 124:19 (2002), 5291–5293.
    • (2002) J. Am. Chem. Soc. , vol.124 , Issue.19 , pp. 5291-5293
    • Carnahan, M.A.1    Middleton, C.2
  • 10
    • 84899085765 scopus 로고    scopus 로고
    • Dendrimers for gene delivery—a potential approach for ocular therapy?
    • Chaplot, S.P., Rupenthal, I.D., Dendrimers for gene delivery—a potential approach for ocular therapy?. J. Pharm. Pharmacol. 66:4 (2014), 542–556.
    • (2014) J. Pharm. Pharmacol. , vol.66 , Issue.4 , pp. 542-556
    • Chaplot, S.P.1    Rupenthal, I.D.2
  • 11
    • 77957357722 scopus 로고    scopus 로고
    • Nanosized dendritic polyguanidilyated translocators for enhanced solubility, permeability, and delivery of gatifloxacin
    • Durairaj, C., Kadam, R.S., et al. Nanosized dendritic polyguanidilyated translocators for enhanced solubility, permeability, and delivery of gatifloxacin. Invest. Ophthalmol. Vis. Sci. 51:11 (2010), 5804–5816.
    • (2010) Invest. Ophthalmol. Vis. Sci. , vol.51 , Issue.11 , pp. 5804-5816
    • Durairaj, C.1    Kadam, R.S.2
  • 12
    • 67650084562 scopus 로고    scopus 로고
    • Dendrimers bind human serum albumin
    • Froehlich, E., Mandeville, J.S., et al. Dendrimers bind human serum albumin. J. Phys. Chem. B 113:19 (2009), 6986–6993.
    • (2009) J. Phys. Chem. B , vol.113 , Issue.19 , pp. 6986-6993
    • Froehlich, E.1    Mandeville, J.S.2
  • 13
    • 84883152474 scopus 로고    scopus 로고
    • An azabisphosphonate-capped poly(phosphorhydrazone) dendrimer for the treatment of endotoxin-induced uveitis
    • Fruchon, S., Caminade, A.M., et al. An azabisphosphonate-capped poly(phosphorhydrazone) dendrimer for the treatment of endotoxin-induced uveitis. Molecules 18:8 (2013), 9305–9316.
    • (2013) Molecules , vol.18 , Issue.8 , pp. 9305-9316
    • Fruchon, S.1    Caminade, A.M.2
  • 14
    • 84883202098 scopus 로고    scopus 로고
    • Novel monodisperse PEGtide dendrons: design, fabrication, and evaluation of mannose receptor-mediated macrophage targeting
    • Gao, J., Chen, P., et al. Novel monodisperse PEGtide dendrons: design, fabrication, and evaluation of mannose receptor-mediated macrophage targeting. Bioconjug. Chem. 24:8 (2013), 1332–1344.
    • (2013) Bioconjug. Chem. , vol.24 , Issue.8 , pp. 1332-1344
    • Gao, J.1    Chen, P.2
  • 15
    • 34948840023 scopus 로고    scopus 로고
    • Designing hydrogel adhesives for corneal wound repair
    • Grinstaff, M.W., Designing hydrogel adhesives for corneal wound repair. Biomaterials 28:35 (2007), 5205–5214.
    • (2007) Biomaterials , vol.28 , Issue.35 , pp. 5205-5214
    • Grinstaff, M.W.1
  • 16
    • 84966429099 scopus 로고    scopus 로고
    • Dendrimers target the ischemic lesion in rodent and primate models of nonarteritic anterior ischemic optic neuropathy
    • Guo, Y., Johnson, M.A., et al. Dendrimers target the ischemic lesion in rodent and primate models of nonarteritic anterior ischemic optic neuropathy. PLoS One, 11(4), 2016, e0154437.
    • (2016) PLoS One , vol.11 , Issue.4 , pp. e0154437
    • Guo, Y.1    Johnson, M.A.2
  • 17
    • 84906054346 scopus 로고    scopus 로고
    • The potential of using biodegradable microspheres in retinal diseases and other intraocular pathologies
    • Herrero-Vanrell, R., Bravo-Osuna, I., et al. The potential of using biodegradable microspheres in retinal diseases and other intraocular pathologies. Prog. Retin Eye Res. 42 (2014), 27–43.
    • (2014) Prog. Retin Eye Res. , vol.42 , pp. 27-43
    • Herrero-Vanrell, R.1    Bravo-Osuna, I.2
  • 18
    • 84873942340 scopus 로고    scopus 로고
    • Liposomes and nanotechnology in drug development: focus on ocular targets
    • Honda, M., Asai, T., et al. Liposomes and nanotechnology in drug development: focus on ocular targets. Int. J. Nanomed. 8 (2013), 495–503.
    • (2013) Int. J. Nanomed. , vol.8 , pp. 495-503
    • Honda, M.1    Asai, T.2
  • 19
    • 0033016739 scopus 로고    scopus 로고
    • Activated polyamidoamine dendrimers, a non-viral vector for gene transfer to the corneal endothelium
    • Hudde, T., Rayner, S.A., et al. Activated polyamidoamine dendrimers, a non-viral vector for gene transfer to the corneal endothelium. Gene Ther. 6:5 (1999), 939–943.
    • (1999) Gene Ther. , vol.6 , Issue.5 , pp. 939-943
    • Hudde, T.1    Rayner, S.A.2
  • 20
    • 81155152766 scopus 로고    scopus 로고
    • Dendrimer-based targeted intravitreal therapy for sustained attenuation of neuroinflammation in retinal degeneration
    • Iezzi, R., Guru, B.R., et al. Dendrimer-based targeted intravitreal therapy for sustained attenuation of neuroinflammation in retinal degeneration. Biomaterials 33:3 (2012), 979–988.
    • (2012) Biomaterials , vol.33 , Issue.3 , pp. 979-988
    • Iezzi, R.1    Guru, B.R.2
  • 21
    • 0037452428 scopus 로고    scopus 로고
    • The influence of surface modification on the cytotoxicity of PAMAM dendrimers
    • Jevprasesphant, R., Penny, J., et al. The influence of surface modification on the cytotoxicity of PAMAM dendrimers. Int. J. Pharm. 252:1–2 (2003), 263–266.
    • (2003) Int. J. Pharm. , vol.252 , Issue.1-2 , pp. 263-266
    • Jevprasesphant, R.1    Penny, J.2
  • 22
    • 84939781019 scopus 로고    scopus 로고
    • Systemic and intravitreal delivery of dendrimers to activated microglia/macrophage in ischemia/reperfusion mouse retina
    • Kambhampati, S.P., Clunies-Ross, A.J., et al. Systemic and intravitreal delivery of dendrimers to activated microglia/macrophage in ischemia/reperfusion mouse retina. Invest. Ophthalmol. Vis. Sci. 56:8 (2015), 4413–4424.
    • (2015) Invest. Ophthalmol. Vis. Sci. , vol.56 , Issue.8 , pp. 4413-4424
    • Kambhampati, S.P.1    Clunies-Ross, A.J.2
  • 23
    • 84860129964 scopus 로고    scopus 로고
    • Dendrimer-based postnatal therapy for neuroinflammation and cerebral palsy in a rabbit model
    • Kannan, S., Dai, H., et al. Dendrimer-based postnatal therapy for neuroinflammation and cerebral palsy in a rabbit model. Sci. Transl. Med., 4(130), 2012, 130ra146.
    • (2012) Sci. Transl. Med. , vol.4 , Issue.130 , pp. 130ra146
    • Kannan, S.1    Dai, H.2
  • 24
    • 84911990896 scopus 로고    scopus 로고
    • Emerging concepts in dendrimer-based nanomedicine: from design principles to clinical applications
    • Kannan, R.M., Nance, E., et al. Emerging concepts in dendrimer-based nanomedicine: from design principles to clinical applications. J. Intern. Med. 276:6 (2014), 579–617.
    • (2014) J. Intern. Med. , vol.276 , Issue.6 , pp. 579-617
    • Kannan, R.M.1    Nance, E.2
  • 25
    • 84893653202 scopus 로고    scopus 로고
    • Dendrimer as nanocarrier for drug delivery
    • Kesharwani, P., Jain, K., et al. Dendrimer as nanocarrier for drug delivery. Prog. Polym. Sci. 39:2 (2014), 268–307.
    • (2014) Prog. Polym. Sci. , vol.39 , Issue.2 , pp. 268-307
    • Kesharwani, P.1    Jain, K.2
  • 26
    • 84875716054 scopus 로고    scopus 로고
    • Use of single-site-functionalized PEG dendrons to prepare gene vectors that penetrate human mucus barriers
    • Kim, A.J., Boylan, N.J., et al. Use of single-site-functionalized PEG dendrons to prepare gene vectors that penetrate human mucus barriers. Angew. Chem. Int. Ed. Engl. 52:14 (2013), 3985–3988.
    • (2013) Angew. Chem. Int. Ed. Engl. , vol.52 , Issue.14 , pp. 3985-3988
    • Kim, A.J.1    Boylan, N.J.2
  • 27
    • 0033657796 scopus 로고    scopus 로고
    • Synthesis of polyamidoamine dendrimers having poly(ethylene glycol) grafts and their ability to encapsulate anticancer drugs
    • Kojima, C., Kono, K., et al. Synthesis of polyamidoamine dendrimers having poly(ethylene glycol) grafts and their ability to encapsulate anticancer drugs. Bioconjug. Chem. 11:6 (2000), 910–917.
    • (2000) Bioconjug. Chem. , vol.11 , Issue.6 , pp. 910-917
    • Kojima, C.1    Kono, K.2
  • 28
    • 84883219531 scopus 로고    scopus 로고
    • Nanomedicines for back of the eye drug delivery, gene delivery, and imaging
    • Kompella, U.B., Amrite, A.C., et al. Nanomedicines for back of the eye drug delivery, gene delivery, and imaging. Prog. Retin. Eye Res. 36 (2013), 172–198.
    • (2013) Prog. Retin. Eye Res. , vol.36 , pp. 172-198
    • Kompella, U.B.1    Amrite, A.C.2
  • 29
    • 0034005436 scopus 로고    scopus 로고
    • Dendrimers: relationship between structure and biocompatibility in vitro, and preliminary studies on the biodistribution of 125I-labelled polyamidoamine dendrimers in vivo
    • Malik, N., Wiwattanapatapee, R., et al. Dendrimers: relationship between structure and biocompatibility in vitro, and preliminary studies on the biodistribution of 125I-labelled polyamidoamine dendrimers in vivo. J. Control. Release 65:1–2 (2000), 133–148.
    • (2000) J. Control. Release , vol.65 , Issue.1-2 , pp. 133-148
    • Malik, N.1    Wiwattanapatapee, R.2
  • 30
    • 4544332801 scopus 로고    scopus 로고
    • Inhibition of in vitro VEGF expression and choroidal neovascularization by synthetic dendrimer peptide mediated delivery of a sense oligonucleotide
    • Marano, R.J., Wimmer, N., et al. Inhibition of in vitro VEGF expression and choroidal neovascularization by synthetic dendrimer peptide mediated delivery of a sense oligonucleotide. Exp. Eye Res. 79:4 (2004), 525–535.
    • (2004) Exp. Eye Res. , vol.79 , Issue.4 , pp. 525-535
    • Marano, R.J.1    Wimmer, N.2
  • 31
    • 27544499791 scopus 로고    scopus 로고
    • Dendrimer delivery of an anti-VEGF oligonucleotide into the eye: a long-term study into inhibition of laser-induced CNV, distribution, uptake and toxicity
    • Marano, R.J., Toth, I., et al. Dendrimer delivery of an anti-VEGF oligonucleotide into the eye: a long-term study into inhibition of laser-induced CNV, distribution, uptake and toxicity. Gene Ther. 12:21 (2005), 1544–1550.
    • (2005) Gene Ther. , vol.12 , Issue.21 , pp. 1544-1550
    • Marano, R.J.1    Toth, I.2
  • 32
    • 84923332900 scopus 로고    scopus 로고
    • Hydroxyl PAMAM dendrimer-based gene vectors for transgene delivery to human retinal pigment epithelial cells
    • Mastorakos, P., Kambhampati, S.P., et al. Hydroxyl PAMAM dendrimer-based gene vectors for transgene delivery to human retinal pigment epithelial cells. Nanoscale 7:9 (2015), 3845–3856.
    • (2015) Nanoscale , vol.7 , Issue.9 , pp. 3845-3856
    • Mastorakos, P.1    Kambhampati, S.P.2
  • 33
    • 84943819912 scopus 로고    scopus 로고
    • Evaluation of protein drug stability with vitreous humor in a novel ex-vivo intraocular model
    • Patel, S., Muller, G., et al. Evaluation of protein drug stability with vitreous humor in a novel ex-vivo intraocular model. Eur. J. Pharm. Biopharm. 95:Pt. B (2015), 407–417.
    • (2015) Eur. J. Pharm. Biopharm. , vol.95 , pp. 407-417
    • Patel, S.1    Muller, G.2
  • 34
    • 28744437107 scopus 로고    scopus 로고
    • Targeted drug delivery with dendrimers: comparison of the release kinetics of covalently conjugated drug and non-covalent drug inclusion complex
    • Patri, A.K., Kukowska-Latallo, J.F., et al. Targeted drug delivery with dendrimers: comparison of the release kinetics of covalently conjugated drug and non-covalent drug inclusion complex. Adv. Drug Deliv. Rev. 57:15 (2005), 2203–2214.
    • (2005) Adv. Drug Deliv. Rev. , vol.57 , Issue.15 , pp. 2203-2214
    • Patri, A.K.1    Kukowska-Latallo, J.F.2
  • 35
    • 34547281547 scopus 로고    scopus 로고
    • Rang and Dale's Pharmacology
    • 6th edition Elsevier
    • Rang, H., Dale, M.M., Ritter, J.M., Flower, R.J., Rang and Dale's Pharmacology. 6th edition, 2008, Elsevier, 431–432.
    • (2008) , pp. 431-432
    • Rang, H.1    Dale, M.M.2    Ritter, J.M.3    Flower, R.J.4
  • 36
    • 84856734898 scopus 로고    scopus 로고
    • Synthesis and fluorescent properties of cationic carbosilane dendrimers containing eugenol linkers for their use in biomedical applications
    • Rasines, B., Sanchez-Nieves, J., et al. Synthesis and fluorescent properties of cationic carbosilane dendrimers containing eugenol linkers for their use in biomedical applications. New J. Chem. 36:2 (2012), 360–370.
    • (2012) New J. Chem. , vol.36 , Issue.2 , pp. 360-370
    • Rasines, B.1    Sanchez-Nieves, J.2
  • 37
    • 84958051260 scopus 로고    scopus 로고
    • A divalent PAMAM-based matrix metalloproteinase/carbonic anhydrase inhibitor for the treatment of dry eye syndrome
    • Richichi, B., Baldoneschi, V., et al. A divalent PAMAM-based matrix metalloproteinase/carbonic anhydrase inhibitor for the treatment of dry eye syndrome. Chemistry 22:5 (2016), 1714–1721.
    • (2016) Chemistry , vol.22 , Issue.5 , pp. 1714-1721
    • Richichi, B.1    Baldoneschi, V.2
  • 38
    • 84979934318 scopus 로고    scopus 로고
    • Optimising the controlled release of dexamethasone from a new generation of PLGA-based microspheres intended for intravitreal administration
    • Rodriguez Villanueva, J., Bravo-Osuna, I., Herrero-Vanrell, R., Molina, I.T., Guzmán, M., Optimising the controlled release of dexamethasone from a new generation of PLGA-based microspheres intended for intravitreal administration. Eur. J. Pharm. Sci., 2016, 10.1016/j.ejps.2016.03.012.
    • (2016) Eur. J. Pharm. Sci.
    • Rodriguez Villanueva, J.1    Bravo-Osuna, I.2    Herrero-Vanrell, R.3    Molina, I.T.4    Guzmán, M.5
  • 39
    • 31544453046 scopus 로고    scopus 로고
    • Biodendrimer-based hydrogel scaffolds for cartilage tissue repair
    • Sontjens, S.H., Nettles, D.L., et al. Biodendrimer-based hydrogel scaffolds for cartilage tissue repair. Biomacromolecules 7:1 (2006), 310–316.
    • (2006) Biomacromolecules , vol.7 , Issue.1 , pp. 310-316
    • Sontjens, S.H.1    Nettles, D.L.2
  • 40
    • 84899090733 scopus 로고    scopus 로고
    • Topical delivery of ocular therapeutics: carrier systems and physical methods
    • Souza, J.G., Dias, K., et al. Topical delivery of ocular therapeutics: carrier systems and physical methods. J. Pharm. Pharmacol. 66:4 (2014), 507–530.
    • (2014) J. Pharm. Pharmacol. , vol.66 , Issue.4 , pp. 507-530
    • Souza, J.G.1    Dias, K.2
  • 41
    • 0021586266 scopus 로고
    • A new class of polymers: starburst-dendritic macromolecules
    • Tomalia, D.A., Baker, H., et al. A new class of polymers: starburst-dendritic macromolecules. Polym. J. 17:1 (1985), 117–132.
    • (1985) Polym. J. , vol.17 , Issue.1 , pp. 117-132
    • Tomalia, D.A.1    Baker, H.2
  • 42
    • 11844250522 scopus 로고    scopus 로고
    • Poly(amidoamine) dendrimers as ophthalmic vehicles for ocular delivery of pilocarpine nitrate and tropicamide
    • Vandamme, T.F., Brobeck, L., Poly(amidoamine) dendrimers as ophthalmic vehicles for ocular delivery of pilocarpine nitrate and tropicamide. J. Control. Release 102:1 (2005), 23–38.
    • (2005) J. Control. Release , vol.102 , Issue.1 , pp. 23-38
    • Vandamme, T.F.1    Brobeck, L.2
  • 43
    • 2942585621 scopus 로고    scopus 로고
    • New dendritic adhesives for sutureless ophthalmic surgical procedures: in vitro studies of corneal laceration repair
    • Velazquez, A.J., Carnahan, M.A., et al. New dendritic adhesives for sutureless ophthalmic surgical procedures: in vitro studies of corneal laceration repair. Arch. Ophthalmol. 122:6 (2004), 867–870.
    • (2004) Arch. Ophthalmol. , vol.122 , Issue.6 , pp. 867-870
    • Velazquez, A.J.1    Carnahan, M.A.2
  • 44
    • 84860389756 scopus 로고    scopus 로고
    • Determination of puerarin in rabbit aqueous humor by liquid chromatography tandem mass spectrometry using microdialysis sampling after topical administration of puerarin PAMAM dendrimer complex
    • Wang, W.Y., Yao, C., et al. Determination of puerarin in rabbit aqueous humor by liquid chromatography tandem mass spectrometry using microdialysis sampling after topical administration of puerarin PAMAM dendrimer complex. J. Pharm. Biomed. Anal. 56:4 (2011), 825–829.
    • (2011) J. Pharm. Biomed. Anal. , vol.56 , Issue.4 , pp. 825-829
    • Wang, W.Y.1    Yao, C.2
  • 45
    • 84893493853 scopus 로고    scopus 로고
    • Synthesis and evaluation of a nanoglobular dendrimer 5-aminosalicylic Acid conjugate with a hydrolyzable schiff base spacer for treating retinal degeneration
    • Wu, X., Yu, G., et al. Synthesis and evaluation of a nanoglobular dendrimer 5-aminosalicylic Acid conjugate with a hydrolyzable schiff base spacer for treating retinal degeneration. ACS Nano 8:1 (2014), 153–161.
    • (2014) ACS Nano , vol.8 , Issue.1 , pp. 153-161
    • Wu, X.1    Yu, G.2
  • 46
    • 84929588725 scopus 로고    scopus 로고
    • Dendrimers in medicine: therapeutic concepts and pharmaceutical challenges
    • Wu, L.P., Ficker, M., et al. Dendrimers in medicine: therapeutic concepts and pharmaceutical challenges. Bioconjug. Chem. 26:7 (2015), 1198–1211.
    • (2015) Bioconjug. Chem. , vol.26 , Issue.7 , pp. 1198-1211
    • Wu, L.P.1    Ficker, M.2
  • 47
    • 84878785223 scopus 로고    scopus 로고
    • Nanotechnology approaches for ocular drug delivery
    • Xu, Q., Kambhampati, S.P., et al. Nanotechnology approaches for ocular drug delivery. Middle East Afr. J. Ophthalmol. 20:1 (2013), 26–37.
    • (2013) Middle East Afr. J. Ophthalmol. , vol.20 , Issue.1 , pp. 26-37
    • Xu, Q.1    Kambhampati, S.P.2
  • 48
    • 77956408400 scopus 로고    scopus 로고
    • Preparation and characterization of puerarin-dendrimer complexes as an ocular drug delivery system
    • Yao, W., Sun, K., et al. Preparation and characterization of puerarin-dendrimer complexes as an ocular drug delivery system. Drug Dev. Ind. Pharm. 36:9 (2010), 1027–1035.
    • (2010) Drug Dev. Ind. Pharm. , vol.36 , Issue.9 , pp. 1027-1035
    • Yao, W.1    Sun, K.2
  • 49
    • 77956104883 scopus 로고    scopus 로고
    • Effect of poly(amidoamine) dendrimers on corneal penetration of puerarin
    • Yao, W.J., Sun, K.X., et al. Effect of poly(amidoamine) dendrimers on corneal penetration of puerarin. Biol. Pharm. Bull. 33:8 (2010), 1371–1377.
    • (2010) Biol. Pharm. Bull. , vol.33 , Issue.8 , pp. 1371-1377
    • Yao, W.J.1    Sun, K.X.2
  • 50
    • 84977495378 scopus 로고    scopus 로고
    • Microglial migration and interactions with dendrimer nanoparticles are altered in the presence of neuroinflammation
    • (65)
    • Zhang, F., Nance, E., et al. Microglial migration and interactions with dendrimer nanoparticles are altered in the presence of neuroinflammation. J. Neuroinflammation, 13(1), 2016 (65).
    • (2016) J. Neuroinflammation , vol.13 , Issue.1
    • Zhang, F.1    Nance, E.2


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