Novel water-soluble mucoadhesive carbosilane dendrimers for ocular administration

Molecular Pharmaceutics

Volumn 13, Issue 9, 2016, Pages 2966-2976

  Bravo Osuna, I ^a,b   Vicario De La Torre, M ^a,b   Andres Guerrero V ^a,b   Sanchez Nieves J ^c,d   Guzman Navarro M ^c   De La Mata, F J ^c,d   Gomez R ^c,d   De Las Heras, B ^a   Argueso P ^e   Ponchel, G ^f   Herrero Vanrell, R ^a,b   Molina Martinez I T ^a,b  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b HOSPITAL CLÍNICO SAN CARLOS   (Spain)

^c UNIVERSITY OF ALCALÁ   (Spain)

^d BIOMATERIALES Y NANOMEDICINA CIBER BBN   (Spain)

^e SCHEPENS EYE RESEARCH INSTITUTE   (United States)

^f UNIV PARIS SUD   (France)

Author keywords

carbosilane dendrimers; hypotensive activity; mucoadhesion; ocular transmembrane mucins; surface plasmon resonance (SPR)

Indexed keywords

ACETAZOLAMIDE; AMMONIA; DENDRIMER; EYE DROPS; MUCIN; SILANE DERIVATIVE; CARBOSILANE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG FORMULATION; DRUG INSTILLATION; DRUG PENETRATION; DRUG TOLERANCE; HUMAN; HUMAN CELL; INTRAOCULAR PRESSURE; MALE; MUCOADHESION; NEW ZEALAND WHITE (RABBIT); NONHUMAN; NORMAL HUMAN; OSMOLARITY; PRIORITY JOURNAL; SURFACE TENSION; ANIMAL; CELL LINE; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; INTRAOCULAR DRUG ADMINISTRATION; LEPORIDAE; SURFACE PLASMON RESONANCE;

ACETAZOLAMIDE; ADMINISTRATION, OPHTHALMIC; ANIMALS; CELL LINE; CELL SURVIVAL; DENDRIMERS; HUMANS; MALE; RABBITS; SILANES; SURFACE PLASMON RESONANCE;

EID: 84984917130     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/acs.molpharmaceut.6b00182     Document Type: Article

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