The Dengue Virus NS5 Protein Intrudes in the Cellular Spliceosome and Modulates Splicing

PLoS Pathogens

Volumn 12, Issue 8, 2016, Pages

  De Maio, Federico A ^a   Risso, Guillermo ^b   Iglesias, Nestor G ^a   Shah, Priya ^c   Pozzi, Berta ^b   Gebhard, Leopoldo G ^a   Mammi, Pablo ^b   Mancini, Estefania ^a   Yanovsky, Marcelo J ^a   Andino, Raul ^c   Krogan, Nevan ^c   Srebrow, Anabella ^b   Gamarnik, Andrea V ^a  

^a FUNDACIÓN INSTITUTO LELOIR   (Argentina)

^b INSTITUTO DE FISIOLOGÍA   (Argentina)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; MONOCLONAL ANTIBODY; NONSTRUCTURAL PROTEIN 5; POLYCLONAL ANTIBODY; PROTEIN BCL X; SMALL NUCLEAR RIBONUCLEOPROTEIN; STAT2 PROTEIN; NS5 PROTEIN, DENGUE VIRUS; VIRAL PROTEIN;

A549 CELL LINE; ALTERNATIVE RNA SPLICING; ARTICLE; CELL FRACTIONATION; CONTROLLED STUDY; DENGUE; DENGUE VIRUS; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; HEPATOCELLULAR CARCINOMA CELL LINE; HIGH THROUGHPUT SEQUENCING; HOST PATHOGEN INTERACTION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; PROTEOMICS; REAL TIME POLYMERASE CHAIN REACTION; RNA PROCESSING; RNAI THERAPEUTICS; SPLICEOSOME; VIRUS RECOMBINANT; VIRUS REPLICATION; WESTERN BLOTTING; ANIMAL; CELL LINE; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; HOST PARASITE INTERACTION; METABOLISM; PATHOGENICITY; PHYSIOLOGY; POLYMERASE CHAIN REACTION; RNA SPLICING; VIROLOGY;

ANIMALS; CELL LINE; DENGUE; DENGUE VIRUS; FLUORESCENT ANTIBODY TECHNIQUE; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HOST-PARASITE INTERACTIONS; HUMANS; POLYMERASE CHAIN REACTION; RIBONUCLEOPROTEIN, U5 SMALL NUCLEAR; RNA SPLICING; SPLICEOSOMES; TRANSFECTION; VIRAL NONSTRUCTURAL PROTEINS;

EID: 84984858050     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1005841     Document Type: Article

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