The interdomain region of dengue NS5 protein that binds to the viral helicase NS3 contains independently functional importin β1 and importin α/β-recognized nuclear localization signals

Journal of Biological Chemistry

Volumn 277, Issue 39, 2002, Pages 36399-36407

  Brooks, Andrew J ^a,b,c   Johansson, Magnus ^a,b,c   John, Anna V ^a,b,c   Xu, Yibin ^a,b,c   Jans, David A ^a,b,c   Vasudevan, Subhash G ^a,b,c  

^a JAMES COOK UNIVERSITY   (Australia)

^b Biology and Environment   (Australia)

^c MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEAR LOCALIZATION SIGNALS;

DISEASES; ENZYMES; RNA; VIRUSES; YEAST;

PHYSIOLOGY;

BETA GALACTOSIDASE; HELICASE; HYBRID PROTEIN; IMPORTIN BETA1; KARYOPHERIN; KARYOPHERIN ALPHA; PROTEIN NS5; RNA DIRECTED RNA POLYMERASE; SPACER DNA; UNCLASSIFIED DRUG; VIRUS PROTEIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; DENGUE VIRUS; FLAVIVIRUS; MOLECULAR RECOGNITION; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; NUCLEOTIDE SEQUENCE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; RAT; VIRUS REPLICATION;

ALPHA KARYOPHERINS; AMINO ACID SEQUENCE; ANIMALS; BETA KARYOPHERINS; BETA-GALACTOSIDASE; BINDING SITES; CARCINOMA, HEPATOCELLULAR; CELL NUCLEUS; DENGUE VIRUS; DIMERIZATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLUORESCENT DYES; GLUTATHIONE TRANSFERASE; KINETICS; MICROSCOPY, FLUORESCENCE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NUCLEAR LOCALIZATION SIGNALS; PLASMIDS; POINT MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RATS; RECOMBINANT FUSION PROTEINS; RNA HELICASES; SEQUENCE HOMOLOGY, AMINO ACID; SERINE ENDOPEPTIDASES; TIME FACTORS; TUMOR CELLS, CULTURED; TWO-HYBRID SYSTEM TECHNIQUES; VIRAL NONSTRUCTURAL PROTEINS;

ANIMALIA; DENGUE VIRUS; FLAVIVIRUS; RNA VIRUSES;

EID: 0037184036     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M204977200     Document Type: Article

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