메뉴 건너뛰기




Volumn 5, Issue AUG, 2014, Pages

Metabolic reprogramming in macrophage polarization

Author keywords

Glycolysis; HIF; Macrophage; Metabolism; PGC 1

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; REACTIVE OXYGEN METABOLITE; STAT6 PROTEIN; CARBOHYDRATE KINASE LIKE PROTEIN; FRUCTOSE 6 PHOSPHATE; GAMMA INTERFERON; GLUCOSE 6 PHOSPHATE; INTERLEUKIN 1ALPHA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1BETA; PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; RIBULOSE PHOSPHATE; TRANSALDOLASE; UNCLASSIFIED DRUG;

EID: 84919452312     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2014.00420     Document Type: Article
Times cited : (730)

References (40)
  • 1
    • 0014736780 scopus 로고
    • Some biochemical aspects of the immune macrophage
    • Hard GC. Some biochemical aspects of the immune macrophage. Br J Exp Pathol (1970) 51(1): 97-105
    • (1970) Br J Exp Pathol , vol.51 , Issue.1 , pp. 97-105
    • Hard, G.C.1
  • 2
    • 0023029455 scopus 로고
    • Metabolism of glucose, glutamine, long-chain fatty acids and ketone bodies by murine macrophages
    • Newsholme P, Curi R, Gordon S, Newsholme, EA. Metabolism of glucose, glutamine, long-chain fatty acids and ketone bodies by murine macrophages. Biochem J. (1986) 239(1): 121-125
    • (1986) Biochem J. , vol.239 , Issue.1 , pp. 121-125
    • Newsholme, P.1    Curi, R.2    Gordon, S.3    Newsholme, E.A.4
  • 3
    • 0025099266 scopus 로고
    • IL4 inhibits superoxide production by human mononuclear phagocytes
    • Abramson SL, Gallin JI. IL4 inhibits superoxide production by human mononuclear phagocytes. J. Immunol (1990) 144(2): 625-630
    • (1990) J. Immunol , vol.144 , Issue.2 , pp. 625-630
    • Abramson, S.L.1    Gallin, J.I.2
  • 4
    • 0026762988 scopus 로고
    • Interleukin 4 potently enhances murine macrophages mannose receptor activity: a marker of alternative immunologic macrophage activation
    • Stein M, Keshaw S, Harris N, Gordon, S. Interleukin 4 potently enhances murine macrophages mannose receptor activity: a marker of alternative immunologic macrophage activation. J. Exp Med (1992) 176(1): 287-292
    • (1992) J. Exp Med , vol.176 , Issue.1 , pp. 287-292
    • Stein, M.1    Keshaw, S.2    Harris, N.3    Gordon, S.4
  • 5
    • 79751496064 scopus 로고    scopus 로고
    • Alternative macrophage activation and metabolism
    • doi: 10.1146/annurev-pathol-011110-130138.
    • Odegaard JI, Chawla, A. Alternative macrophage activation and metabolism. Annu. Rev. Pathol. (2011) 6: 275-297 doi: 10.1146/annurev-pathol-011110-130138
    • (2011) Annu. Rev. Pathol. , vol.6 , pp. 275-297
    • Odegaard, J.I.1    Chawla, A.2
  • 6
    • 0026573148 scopus 로고
    • Stimulation of glycolysis as an activation signal in rat peritoneal macrophages: effect of glucocorticoids on this process
    • Bustos R, Sobrino F. Stimulation of glycolysis as an activation signal in rat peritoneal macrophages: effect of glucocorticoids on this process. Biochem J (1992) 282: 299-303
    • (1992) Biochem J , vol.282 , pp. 299-303
    • Bustos, R.1    Sobrino, F.2
  • 7
    • 0028919209 scopus 로고
    • Arginase induction by suppressors of nitric oxide synthesis (IL4, IL10, PGE2) in murine bone-marrow derived macrophages
    • Corraliza IM, Soler G, Eichmann K, Modolell, M. Arginase induction by suppressors of nitric oxide synthesis (IL4, IL10, PGE2) in murine bone-marrow derived macrophages. Biochem Biophys Res Commun (1995) 206(2): 667-673
    • (1995) Biochem Biophys Res Commun , vol.206 , Issue.2 , pp. 667-673
    • Corraliza, I.M.1    Soler, G.2    Eichmann, K.3    Modolell, M.4
  • 8
    • 0032102990 scopus 로고    scopus 로고
    • Alternative metabolic states in murine macrophages reflected by the nitric oxide synthase/arginase balance: competitive regulation by CD4+ Tcells correlates with Th1/Th2 phenotype
    • Munder M, Eichmann K, Modolell M. Alternative metabolic states in murine macrophages reflected by the nitric oxide synthase/arginase balance: competitive regulation by CD4+ Tcells correlates with Th1/Th2 phenotype. J. Immunol. (1998) 160(11): 5347-5354
    • (1998) J. Immunol. , vol.160 , Issue.11 , pp. 5347-5354
    • Munder, M.1    Eichmann, K.2    Modolell, M.3
  • 9
    • 84882579352 scopus 로고    scopus 로고
    • Evaluation of arginine metabolism for the analysis of m1/m2 macrophage activation in human clinical specimens
    • doi: 10.1007/s00011-013-0642-z.
    • Geelhard-Karsch A, Schinnerling K, Conrad K, Friebel J, Allers K, Schneider T, et al. Evaluation of arginine metabolism for the analysis of m1/m2 macrophage activation in human clinical specimens. Inflam. Res (2013) 62: 865-869 doi: 10.1007/s00011-013-0642-z
    • (2013) Inflam. Res , vol.62 , pp. 865-869
    • Geelhard-Karsch, A.1    Schinnerling, K.2    Conrad, K.3    Friebel, J.4    Allers, K.5    Schneider, T.6
  • 10
    • 79955532516 scopus 로고    scopus 로고
    • TLR signaling augments macrophage bactericidal activity through mitochondrial ROS
    • doi: 101038/nature09973.
    • West AP, Brodsky IE, Rahner C, Woo DK, Erdjument-Bromage H, Tempst P, et al TLR signaling augments macrophage bactericidal activity through mitochondrial ROS. Nature (2011) 472(7344): 476-480 doi: 10.1038/nature09973
    • (2011) Nature , vol.472 , Issue.7344 , pp. 476-480
    • West, A.P.1    Brodsky, I.E.2    Rahner, C.3    Woo, D.K.4    Erdjument-Bromage, H.5    Tempst, P.6
  • 11
    • 2542455472 scopus 로고    scopus 로고
    • iNOS-mediated nitric oxide production and its regulation
    • Aktan F. iNOS-mediated nitric oxide production and its regulation. Life Sci (2004) 75(6): 639-653
    • (2004) Life Sci , vol.75 , Issue.6 , pp. 639-653
    • Aktan, F.1
  • 12
    • 77956213727 scopus 로고    scopus 로고
    • Substrate fate in activated macrophages: a comparison between innate, classic and alternative activation
    • doi: 104049/jimmunol.0901698.
    • Rodríguez-Prados JC, Través PG, Cuenca J, Rico D, Aragonés J, Martín-Sanz P, et al Substrate fate in activated macrophages: a comparison between innate, classic and alternative activation. J. Immunol (2010) 185(1): 605-614 doi: 10.4049/jimmunol.0901698
    • (2010) J. Immunol , vol.185 , Issue.1 , pp. 605-614
    • Rodríguez-Prados, J.C.1    Través, P.G.2    Cuenca, J.3    Rico, D.4    Aragonés, J.5    Martín-Sanz, P.6
  • 13
    • 33745428666 scopus 로고    scopus 로고
    • Oxidative metabolism and PGC-1β attenuate macrophage-mediated inflammation
    • Vats D, Mukundan L, Odegaard JI, Zhang L, Smith KL, Morel CR, et al Oxidative metabolism and PGC-1β attenuate macrophage-mediated inflammation. Cell Metab (2006) 4(1): 13-14
    • (2006) Cell Metab , vol.4 , Issue.1 , pp. 13-14
    • Vats, D.1    Mukundan, L.2    Odegaard, J.I.3    Zhang, L.4    Smith, K.L.5    Morel, C.R.6
  • 14
    • 84862016400 scopus 로고    scopus 로고
    • The sedoheptulose kinase CARKL directs macrophage polarization through control of glucose metabolism
    • doi: 101016/j.cmet.2012.04.023.
    • Haschemi A, Kosma P, Gille L, Evans CR, Burant CF, Starkl P, et al The sedoheptulose kinase CARKL directs macrophage polarization through control of glucose metabolism. Cell Metab (2012) 15(6): 813-826 doi: 10.1016/j.cmet.2012.04.023
    • (2012) Cell Metab , vol.15 , Issue.6 , pp. 813-826
    • Haschemi, A.1    Kosma, P.2    Gille, L.3    Evans, C.R.4    Burant, C.F.5    Starkl, P.6
  • 15
    • 84876285741 scopus 로고    scopus 로고
    • Succinate is an inflammatory signal that induces IL-1β through HIF- 1a
    • doi: 101038/nature11986.
    • Tannahill GM, Curtis AM, Adamik J, Palsson-McDermott EM, McGettrick AF, Goel G, et al Succinate is an inflammatory signal that induces IL-1β through HIF- 1a. Nature (2013) 496(7444): 238-242 doi: 10.1038/nature11986
    • (2013) Nature , vol.496 , Issue.7444 , pp. 238-242
    • Tannahill, G.M.1    Curtis, A.M.2    Adamik, J.3    Palsson-McDermott, E.M.4    McGettrick, A.F.5    Goel, G.6
  • 16
    • 0038036024 scopus 로고    scopus 로고
    • Bioenergetic analysis of peroxisome proliferator-activated receptor gamma coactivators 1alpha and 1beta (PGC-1a and PGC-1β) in muscle cells
    • St-Pierre J, Lin J, Krauss S, Tarr PT, Yang R, Newgard CB, et al Bioenergetic analysis of peroxisome proliferator-activated receptor gamma coactivators 1alpha and 1beta (PGC-1a and PGC-1β) in muscle cells. J. Biol. Chem. (2003) 278(29): 26597-26603
    • (2003) J. Biol. Chem. , vol.278 , Issue.29 , pp. 26597-26603
    • St-Pierre, J.1    Lin, J.2    Krauss, S.3    Tarr, P.T.4    Yang, R.5    Newgard, C.B.6
  • 17
    • 77955415616 scopus 로고    scopus 로고
    • PGC-1 beta-regulated mitochondrial biogenesis and function in myotubes is mediated by NRF-1 and ERR alpha
    • doi: 101016/j.mito.2010.05.012.
    • Shao D, Liu Y, Liu X, Zhu L, Cui Y, Cui A, et al PGC-1 beta-regulated mitochondrial biogenesis and function in myotubes is mediated by NRF-1 and ERR alpha Mitochondrion (2010) 10(5): 516-527 doi: 10.1016/j.mito.2010.05.012
    • (2010) Mitochondrion , vol.10 , Issue.5 , pp. 516-527
    • Shao, D.1    Liu, Y.2    Liu, X.3    Zhu, L.4    Cui, Y.5    Cui, A.6
  • 18
  • 19
    • 44349112305 scopus 로고    scopus 로고
    • Adipocyte-derived Th2 cytokines and myeloid PPARδ regulate macrophage polarization and insulin sensitivity
    • doi: 101016/j.cmet.2008.04.002.
    • Kang K, Reilly SM, Karabacak V, Gangl MR, Fitzgerald K, Hatano B, et al Adipocyte-derived Th2 cytokines and myeloid PPARδ regulate macrophage polarization and insulin sensitivity. Cell Metab (2008) 7(6): 485-495 doi: 10.1016/j.cmet.2008.04.002
    • (2008) Cell Metab , vol.7 , Issue.6 , pp. 485-495
    • Kang, K.1    Reilly, S.M.2    Karabacak, V.3    Gangl, M.R.4    Fitzgerald, K.5    Hatano, B.6
  • 20
    • 84900541832 scopus 로고    scopus 로고
    • TIPE2 negatively regulates inflammation by switching arginine metabolism from nitric oxide synthase to arginase
    • doi: 101371/journal.pone.0096508.
    • Lou Y, Zhang G, Geng M, Zhang W, Cui J, Liu S. TIPE2 negatively regulates inflammation by switching arginine metabolism from nitric oxide synthase to arginase. PLoS One (2014) 9(5): e96508 doi: 10.1371/journal.pone.0096508
    • (2014) PLoS One , vol.9 , Issue.5
    • Lou, Y.1    Zhang, G.2    Geng, M.3    Zhang, W.4    Cui, J.5    Liu, S.6
  • 22
    • 0033870281 scopus 로고    scopus 로고
    • The expression and distribution of the hypoxia-inducible factors HIF1α and HIF2a in normal human tissues, cancers, and tumor-associated macrophages
    • Talks KL, Turley H, Gatter KC, Maxwell PH, Pugh CW, Ratcliffe PJ, et al The expression and distribution of the hypoxia-inducible factors HIF1α and HIF2a in normal human tissues, cancers, and tumor-associated macrophages. Am J Pathol (2000) 157(2): 411-421
    • (2000) Am J Pathol , vol.157 , Issue.2 , pp. 411-421
    • Talks, K.L.1    Turley, H.2    Gatter, K.C.3    Maxwell, P.H.4    Pugh, C.W.5    Ratcliffe, P.J.6
  • 23
    • 68249140395 scopus 로고    scopus 로고
    • Hypoxia-inducible factors 1 and 2 are important transcriptional effectors in primary macrophages experiencing hypoxia
    • doi: 101182/blood-2008-12-195941.
    • Fang HY, Hughes R, Murdoch C, Coffelt SB, Bismas SK, Harris AL, et al Hypoxia-inducible factors 1 and 2 are important transcriptional effectors in primary macrophages experiencing hypoxia. Blood (2009) 114(4): 844-859 doi: 10.1182/blood-2008-12-195941
    • (2009) Blood , vol.114 , Issue.4 , pp. 844-859
    • Fang, H.Y.1    Hughes, R.2    Murdoch, C.3    Coffelt, S.B.4    Bismas, S.K.5    Harris, A.L.6
  • 24
    • 77649177217 scopus 로고    scopus 로고
    • Differential activation and antagonistic function of HIF-α isoforms in macrophages are essential for NO homeostasis
    • doi: 101101/gad.1881410.
    • Takeda N, O'Dea EL, Doedens A, Kim JW, Weidemann A, Stockmann C, et al Differential activation and antagonistic function of HIF-α isoforms in macrophages are essential for NO homeostasis. Genes Dev (2010) 24(5): 491-501 doi: 10.1101/gad.1881410
    • (2010) Genes Dev , vol.24 , Issue.5 , pp. 491-501
    • Takeda, N.1    O'Dea, E.L.2    Doedens, A.3    Kim, J.W.4    Weidemann, A.5    Stockmann, C.6
  • 26
    • 18944375453 scopus 로고    scopus 로고
    • Arginase-1 and Ym1 are markers for murine, but not human, alternatively activated myeloid cells
    • author reply 6561-6562
    • Raes G, Den Bergh VR, De Baetselier P, Ghassabeh GH, Scotton C, Locati M, et al Arginase-1 and Ym1 are markers for murine, but not human, alternatively activated myeloid cells. J Immunol (2005) 174(11): 6561; author reply 6561-6562
    • (2005) J Immunol , vol.174 , Issue.11 , pp. 6561
    • Raes, G.1    Den Bergh, V.R.2    De Baetselier, P.3    Ghassabeh, G.H.4    Scotton, C.5    Locati, M.6
  • 27
    • 84902136675 scopus 로고    scopus 로고
    • Proteomic characterization of human proinflammatory M1 and anti-inflammatory M2 macrophages and their response to Candida albicans
    • doi: 101002/pmic.201300508.
    • Reales-Calderon JA, Aguilera-Montilla N, Corbi AL, Molero G, Gil C. Proteomic characterization of human proinflammatory M1 and anti-inflammatory M2 macrophages and their response to Candida albicans. Proteomics (2014) 14(12): 1503-1518 doi: 10.1002/pmic.201300508
    • (2014) Proteomics , vol.14 , Issue.12 , pp. 1503-1518
    • Reales-Calderon, J.A.1    Aguilera-Montilla, N.2    Corbi, A.L.3    Molero, G.4    Gil, C.5
  • 28
    • 84903957169 scopus 로고    scopus 로고
    • Fatty acid oxidation is dispensable for human macrophage IL4-induced polarization
    • doi: 101016/j.bbalip.2014.06.007.
    • Namgaladze D, Brüne B. Fatty acid oxidation is dispensable for human macrophage IL4-induced polarization. Biochem Biophys Acta (2014) 1841(9): 1329-1335 doi: 10.1016/j.bbalip.2014.06.007
    • (2014) Biochem Biophys Acta , vol.1841 , Issue.9 , pp. 1329-1335
    • Namgaladze, D.1    Brüne, B.2
  • 29
    • 0029592781 scopus 로고
    • On the expression of nitric oxide synthase by human macrophages, Why no NO?
    • Albina JE. On the expression of nitric oxide synthase by human macrophages. Why no NO? J Leukoc Biol (1995) 58 (6): 643-649
    • (1995) J Leukoc Biol , vol.58 , Issue.6 , pp. 643-649
    • Albina, J.E.1
  • 30
    • 84896508960 scopus 로고    scopus 로고
    • Epigenetic silencing of the human NOS2 gene: rethinking the role of nitric oxide in human macrophage inflammatory responses
    • doi: 10.4049/jimmunol.1301758.
    • Gross TJ, Kremens K, Powers LS, Brink B, Knutson T, Domann FE, et al Epigenetic silencing of the human NOS2 gene: rethinking the role of nitric oxide in human macrophage inflammatory responses. J Immunol 2014 192(5): 2326-2338 doi: 10.4049/jimmunol.1301758
    • (2014) J Immunol , vol.192 , Issue.5 , pp. 2326-2338
    • Gross, T.J.1    Kremens, K.2    Powers, L.S.3    Brink, B.4    Knutson, T.5    Domann, F.E.6
  • 31
    • 0029831335 scopus 로고    scopus 로고
    • et al Increased expression of blood mononuclear cell nitric oxide synthase type 2 in rheumatoid arthritis patients
    • St Clair EW, Wilkinson WE, Lang T, Sanders L, Misukonis MA, Gilkeson GS. et al Increased expression of blood mononuclear cell nitric oxide synthase type 2 in rheumatoid arthritis patients. J Exp Med (1996) 184(3): 1173-1178
    • (1996) J Exp Med , vol.184 , Issue.3 , pp. 1173-1178
    • St Clair, E.W.1    Wilkinson, W.E.2    Lang, T.3    Sanders, L.4    Misukonis, M.A.5    Gilkeson, G.S.6
  • 32
    • 10144237206 scopus 로고    scopus 로고
    • Nitric oxide in Tanzanian children with malaria: inverse relationship between malaria severity and nitric oxide production/nitric oxide synthase type 2 expression
    • Anstey NM, Weinberg JB, Hassanali MY, Mwaikambo ED, Manyenga D, Misukonis MA, et al Nitric oxide in Tanzanian children with malaria: inverse relationship between malaria severity and nitric oxide production/nitric oxide synthase type 2 expression. J Exp Med (1996) 184(2): 557-567
    • (1996) J Exp Med , vol.184 , Issue.2 , pp. 557-567
    • Anstey, N.M.1    Weinberg, J.B.2    Hassanali, M.Y.3    Mwaikambo, E.D.4    Manyenga, D.5    Misukonis, M.A.6
  • 33
    • 0025687404 scopus 로고
    • Human alveolar and peritoneal macrophages mediate fungistasis independently of L-arginine oxidation to nitrite or nitrate
    • Cameron ML, Granger DL, Weinberg JB, Kozumbo WJ, Koren HS. Human alveolar and peritoneal macrophages mediate fungistasis independently of L-arginine oxidation to nitrite or nitrate. Am Rev Respir Dis (1990) 142: 1313-1319
    • (1990) Am Rev Respir Dis , vol.142 , pp. 1313-1319
    • Cameron, M.L.1    Granger, D.L.2    Weinberg, J.B.3    Kozumbo, W.J.4    Koren, H.S.5
  • 34
    • 0027175225 scopus 로고
    • Nitric oxide synthase is not a constituent of the antimicrobial armature of human mononuclear phagocytes
    • Schneeman M, Schoedon G, Hofer S, Blau N, Guerrero L, Shaffner A. Nitric oxide synthase is not a constituent of the antimicrobial armature of human mononuclear phagocytes. J Infect Dis (1993) 167: 1358-1363
    • (1993) J Infect Dis , vol.167 , pp. 1358-1363
    • Schneeman, M.1    Schoedon, G.2    Hofer, S.3    Blau, N.4    Guerrero, L.5    Shaffner, A.6
  • 35
    • 84899446511 scopus 로고    scopus 로고
    • AMPK promotes macrophage fatty acid oxidative metabolism to mitigate inflammation: implications for diabetes and cardiovascular disease
    • doi: 10.1038/icb.2014.11.
    • Steinberg GR, Schertzer JD. AMPK promotes macrophage fatty acid oxidative metabolism to mitigate inflammation: implications for diabetes and cardiovascular disease. Immunol Cell Biol (2014) 92 (4)3: 40-345 doi: 10.1038/icb.2014.11
    • (2014) Immunol Cell Biol , vol.92 , Issue.3-4 , pp. 40-345
    • Steinberg, G.R.1    Schertzer, J.D.2
  • 36
    • 79952135247 scopus 로고    scopus 로고
    • An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice
    • doi: 101172/JCI44490.
    • Sindrilaru A, Peters T, Wieschalka S, Baican C, Baican A, Peter H et al An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice. J Clin Invest (2011) 121(3): 985-997 doi: 101172/JCI44490
    • (2011) J Clin Invest , vol.121 , Issue.3 , pp. 985-997
    • Sindrilaru, A.1    Peters, T.2    Wieschalka, S.3    Baican, C.4    Baican, A.5    Peter, H.6
  • 37
    • 72249112548 scopus 로고    scopus 로고
    • Impaired immune functions of monocytes and macrophages in Whipple's disease
    • doi: 101053/j.gastro.2009.07.066.
    • Moos V, Schmidt C, Geelhar A, Kunkel D, Allers K, Schinnerling K et al Impaired immune functions of monocytes and macrophages in Whipple's disease. Gastroenterology (2010) 138(1): 210-220 doi: 10.1053/j.gastro.2009.07.066
    • (2010) Gastroenterology , vol.138 , Issue.1 , pp. 210-220
    • Moos, V.1    Schmidt, C.2    Geelhar, A.3    Kunkel, D.4    Allers, K.5    Schinnerling, K.6
  • 39
    • 0025201335 scopus 로고
    • Intraperitoneal recombinant gamma interferon in patients with recurrent ascetic ovarian carcinoma: modulation of cytotoxicity and cytokine production in tumor-associated effectors and of major histocompatibility antigen expression on tumor cells
    • Allavena P, Peccatori F, Maggioni D, Erroi A, Sironi M, Colombo N, et al Intraperitoneal recombinant gamma interferon in patients with recurrent ascetic ovarian carcinoma: modulation of cytotoxicity and cytokine production in tumor-associated effectors and of major histocompatibility antigen expression on tumor cells. Cancer Res (1990) 50(22): 7318-7323
    • (1990) Cancer Res , vol.50 , Issue.22 , pp. 7318-7323
    • Allavena, P.1    Peccatori, F.2    Maggioni, D.3    Erroi, A.4    Sironi, M.5    Colombo, N.6
  • 40
    • 0026562566 scopus 로고
    • Anti-tumor and immunomodulatory activity of intraperitoneal IFN-gamma in ovarian carcinoma patients with minimal residual tumor after chemotherapy
    • Colombo N, Peccatori F, Paganin C, Bini S, Brandely M, Mangioni C, et al Anti-tumor and immunomodulatory activity of intraperitoneal IFN-gamma in ovarian carcinoma patients with minimal residual tumor after chemotherapy. Int J Cancer (1992) 51(1): 42-46
    • (1992) Int J Cancer , vol.51 , Issue.1 , pp. 42-46
    • Colombo, N.1    Peccatori, F.2    Paganin, C.3    Bini, S.4    Brandely, M.5    Mangioni, C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.