Disruption of the sugar-sensing receptor T1R2 attenuates metabolic derangements associated with diet-induced obesity

American Journal of Physiology - Endocrinology and Metabolism

Volumn 310, Issue 8, 2016, Pages E688-E698

  Smith, Kathleen R ^a   Hussain, Tania ^a   Azari, Elnaz Karimian ^a   Steiner, Jennifer L ^a   Ayala, Julio E ^a   Pratley, Richard E ^a,b   Kyriazis, George A ^a,b  

^a BURNHAM INSTITUTE   (United States)

^b FLORIDA HOSPITAL   (United States)

Author keywords

Body composition; Diabetes; Hyperinsulinemia; Obesity; Sweet taste receptors

Indexed keywords

FECES LIPID; GLYCEROL; INSULIN; LIVER TRIACYLGLYCEROL LIPASE; RECEPTOR; SUGAR SENSING RECEPTOR T1R2; UNCLASSIFIED DRUG; AMINO ACID; CHROMIUM; G PROTEIN COUPLED RECEPTOR; GLUCOSE TOLERANCE TEST; NICOTINIC ACID DERIVATIVE; TASTE RECEPTORS, TYPE 1; TLR3 PROTEIN, MOUSE; TOLL LIKE RECEPTOR 3; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY COMPOSITION; CONTROLLED STUDY; DIET INDUCED OBESITY; ENERGY BALANCE; FAT MASS; FATTY ACID OXIDATION; GLUCOSE HOMEOSTASIS; GLUCOSE INTOLERANCE; GLUCOSE OXIDATION; GLYCEROL BLOOD LEVEL; HYPERINSULINEMIA; INDIRECT CALORIMETRY; INSULIN BLOOD LEVEL; LIPID ABSORPTION; LIPID BLOOD LEVEL; LIPID DIET; LIPID METABOLISM; LOW CARBOHYDRATE DIET; MALE; METABOLIC DISORDER; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TISSUE SPECIFICITY; WHITE ADIPOSE TISSUE; ADIPOSE TISSUE; ANIMAL; BODY WEIGHT; ENERGY METABOLISM; GENETICS; GLUCOSE BLOOD LEVEL; HOMEOSTASIS; HYPERINSULINISM; KNOCKOUT MOUSE; LIVER; METABOLISM; OBESITY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

ADIPOSE TISSUE; AMINO ACIDS; ANIMALS; BLOOD GLUCOSE; BODY COMPOSITION; BODY WEIGHT; CHROMIUM; DIET, CARBOHYDRATE-RESTRICTED; DIET, HIGH-FAT; ENERGY METABOLISM; GLUCOSE INTOLERANCE; HOMEOSTASIS; HYPERINSULINISM; INSULIN; LIVER; MALE; MICE; MICE, KNOCKOUT; NICOTINIC ACIDS; OBESITY; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, G-PROTEIN-COUPLED; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TOLL-LIKE RECEPTOR 3; TRIGLYCERIDES; UP-REGULATION;

EID: 84983730589     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00484.2015     Document Type: Article

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