Sweet taste receptors regulate basal insulin secretion and contribute to compensatory insulin hypersecretion during the development of diabetes in male mice

Endocrinology

Volumn 155, Issue 6, 2014, Pages 2112-2121

  Kyriazis, George A ^a,b   Smith, Kathleen R ^a   Tyrberg, Björn ^c   Hussain, Tania ^a   Pratley, Richard E ^b  

^a BURNHAM INSTITUTE   (United States)

^b FLORIDA HOSPITAL   (United States)

^c ASTRAZENECA R AND D   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

G PROTEIN COUPLED RECEPTOR; GLUCOSE; INSULIN; SWEET TASTE RECEPTOR; UNCLASSIFIED DRUG; TASTE RECEPTORS, TYPE 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG TARGETING; GENE SILENCING; GLUCOSE METABOLISM; HUMAN; HUMAN CELL; HYPERGLYCEMIA; HYPERINSULINEMIA; INSULIN RELEASE; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; ANIMAL; CELL CULTURE; GENETICS; METABOLISM; REAL TIME POLYMERASE CHAIN REACTION; SECRETION (PROCESS);

ANIMALS; CELLS, CULTURED; DIABETES MELLITUS, TYPE 2; HUMANS; INSULIN; INSULIN-SECRETING CELLS; MALE; MICE; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, G-PROTEIN-COUPLED;

EID: 84901450576     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2013-2015     Document Type: Article

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