Increased ADAMTS1 mediates SPARC-dependent collagen deposition in the aging myocardium

American Journal of Physiology - Endocrinology and Metabolism

Volumn 310, Issue 11, 2016, Pages E1027-E1035

  Toba, Hiroe ^a,b   de Castro Brás, Lisandra E ^a,c   Baicu, Catalin F ^d   Zile, Michael R ^d,e   Lindsey, Merry L ^a,f   Bradshaw, Amy D ^d,e  

^a UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

^b KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

^c EAST CAROLINA UNIVERSITY   (United States)

^d MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^e RALPH H JOHNSON VA MEDICAL CENTER   (United States)

^f G V SONNY MONTGOMERY VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

A disintegrin and metalloproteinase with thrombospondin like motifs 1; Fibroblast; Heart; Matrix metalloproteinase; Secreted protein acidic and rich in cysteine

Indexed keywords

ADAMTS1 PROTEIN; CADHERIN; COLLAGEN; COLLAGEN TYPE 1; COLLAGENASE 3; DISINTEGRIN; FIBRILLAR COLLAGEN; MATRIX METALLOPROTEINASE 15; METALLOPROTEINASE; OSTEONECTIN; SMAD2 PROTEIN; THROMBOSPONDIN; TRANSFORMING GROWTH FACTOR BETA1; VASCULAR CELL ADHESION MOLECULE 1; VERSICAN; ADAMTS1 PROTEIN, MOUSE; SCLEROPROTEIN; SPARC PROTEIN, MOUSE;

ADULT; AGING; ANIMAL EXPERIMENT; ARTICLE; CARDIAC MUSCLE; CONDITIONED MEDIUM; CONTROLLED STUDY; FEMALE; GROUPS BY AGE; HEART FIBROBLAST; HEART MUSCLE COMPLIANCE; HEART MUSCLE FIBROSIS; MALE; MIDDLE AGED; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; YOUNG ADULT; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL CULTURE; EXTRACELLULAR MATRIX; FIBROBLAST; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION; UPREGULATION;

ADAMTS1 PROTEIN; AGING; ANIMALS; CELLS, CULTURED; COLLAGEN; EXTRACELLULAR MATRIX; EXTRACELLULAR MATRIX PROTEINS; FEMALE; FIBROBLASTS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYOCARDIUM; OSTEONECTIN; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 84983628399     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00040.2016     Document Type: Article

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