Integrins and the myocardium

Circulation Research

Volumn 88, Issue 11, 2001, Pages 1112-1119

  Ross, Robert S ^a   Borg, Thomas K ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF SOUTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Extracellular matrix; Integrin; Myocardium

Indexed keywords

INTEGRIN;

EXTRACELLULAR MATRIX; HEART DEVELOPMENT; HEART MUSCLE; HEART MUSCLE CELL; MAMMAL; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION;

EID: 0035827723     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/hh1101.091862     Document Type: Review

References (102)

1. Regulation of the actin cytoskeleton, integrins and cell growth by the Rho family of small GTPases
2. Cell adhesion: Old and new questions
3. Integrin signaling
4. Integrin signaling in vascular biology
5. Integrin signaling: The platelet paradigm
6. Integrins: A family of cell surface receptors
7. Relationships between fibronectin and the cytoskeleton
8. Studies on the function of cell surface glycoproteins, I: Use of antisera to surface membranes in the identification of membrane components relevant to cell-substrate adhesion
9. Membrane glycoproteins involved in cell-substratum adhesion
10. Cleavage of a 135 kD cell surface glycoprotein correlates with loss of fibroblast adhesion to fibronectin
11. Identification and isolation of a 140 kd cell surface glycoprotuin with properties expected of a fibronectin receptor
12. Binding of fibronectin to α-granule-deficient platelets
13. Structure of integrin, a glycoprotein involved in the transmembrane linkage between fibronectin and actin
14. A monoclonal antibody detaches embryonic skeletal muscle from extracellular matrices
15. Monoclonal antibodies which alter the morphology of cultured chick myogenic cells
16. Integrin structure
17. The integrin β subunit
18. Integrins: Alternative splicing as a mechanism to regulate ligand binding and integrin signaling events
19. 7 integrin cytoplasmic domains during skeletal muscle development: Alternate forms, conformational change, and homologies with serine/threonine kinases and tyrosine phosphatases
20. 1 integrin in muscle development and disease
21. 1 integrin expressed in skeletal and cardiac muscle
22. 1 integrin isoform produced by alternative splicing: Unique expression in cardiac and skeletal muscle
23. 3-Integrin-mediated focal adhesion complex formation: Adult cardiocytes embedded in three-dimensional polymer matrices
24. Expression of collagen adhesion proteins and their association with the cytoskeleton in cardiac myocytes
25. Expression of collagen binding integrins during cardiac development and hypertrophy
26. Expression of α and β integrins during terminal differentiation of cardiomyocytes
27. Cellular basis of mechanotransduction
28. Mechanical regulation of cardiac myocyte protein turnover and myofibrillar structure
29. Regulation of cardiac myocyte protein turnover and myofibrillar structure in vitro by specific directions of stretch
30. A potential role for mechanical stimulation in cardiac development
31. Integrins and signal transduction pathways: The road taken
32. 2-adrenoceptor signalling in cat atrial myocytes
33. 2+ current in cat atrial myocytes
34. Bidirectional signaling between the cytoskeleton and integrins
35. Calreticulin is essential for integrin-mediated calcium signalling and cell adhesion
36. Focal adhesion kinase and paxillin bind to peptides mimicking β integrin cytoplasmic domains
37. 1 integrin binding protein (MIBP) that modulates myogenic differentiation
38. 1 integrin cytoplasmic domain
39. Biophysical methods for the determination of antibody-antigen affinities
40. Specialization at the Z line of cardiac myocytes
41. Cell biology of cardiac development
42. 1 integrins are critical for fetal ventricular myocyte proliferation
43. The role of extracellular matrix in cardiogenesis
44. Toward a molecular understanding of congenital heart disease
45. Expression and accumulation of interstitial collagen in the neonatal rat heart
46. Distribution of β-1 integrin in the developing rat heart
47. Modulation of cardiac myocyte phenotype in vitro by the composition and orientation of the extracellular matrix
48. Fibronectins are essential for heart and blood vessel morphogenesis but are dispensable for initial specification of precursor cells
49. Targeted mutations in cell adhesion genes: What have we learned from them?
50. Defective development of the embryonic and extraembryonic circulatory systems in vascular cell adhesion molecule (VCAM-1) deficient mice
51. 4 integrins are essential in placental and cardiac development
52. 1 integrin gene in embryonic stem cells affects morphology, adhesion, and migration but not integration into the inner cell mass of blastocysts
53. 1 integrins in mice results in inner cell mass failure and peri-implantation lethality
54. 1 exon D define distinct roles for integrin splice variants in heart function and embryonic development
55. 1 integrin gene results in progressive fibrosis and heart failure
56. 1 by homologous recombination permits normal murine development but gives rise to a specific deficit in cell adhesion
57. Connective tissue and the heart: Functional significance and regulatory mechanisms
58. Increased expression of cytoskeletal, linkage, and extracellular proteins in failing human myocardium
59. Disruption of the myocardial extracellular matrix leads to cardiac dysfunction
60. 2 chain during normal and pathological growth of myocardium in rat and human
61. The extracellular matrix in the failing human heart
62. Physiology and homeostasis of extracellular matrix: Cardiovascular adaptation and remodeling
63. Fibronectin expression during physiological and pathological cardiac growth
64. Accumulation of fetal fibronectin mRNAs during the development of rat cardiac hypertrophy induced by pressure overload
65. 1D-integrin and FAK are involved in cardiac myocyte hypertrophic response pathway
66. 1 Integrins participate in the hypertrophic response of rat ventricular myocytes
67. Integrin signaling in pressure-overload hypertrophy
68. Association of tyrosine-phosphorylated c-Src with the cytoskeleton of hypertrophying myocardium
69. Communication between myocytes and fibroblasts in cardiac remodeling in angiotensin chimeric mice
70. Modulation of heart fibroblast migration and collagen gel contraction by IGF-I
71. Design and construction of a uniaxial cell stretcher
72. Angiotensin II, adhesion, and cardiac fibrosis
73. 3 integrin expression in rat neonatal cardiac fibroblasts
74. Angiotensin II has multiple profibrotic effects in human cardiac fibroblasts
75. Integrins, adhesion, and cardiac remodeling
76. Assessment of cardiac function and gene expression at an early phase after myocardial infarction
77. Remodeling of cell-cell and cell-extracellular matrix interactions at the border zone of rat myocardial infarcts
78. Differences in time course of myocardial mRNA expression in non-infarcted myocardium after myocardial infarction
79. Infarct scar: A dynamic tissue
80. Increased expression of fibronectin isoforms after myocardial infarction in rats
81. Structural and mechanical factors influencing infarct scar collagen organization
82. 5 integrin subunits in acute and chronic stages of myocardial infarction in rats
83. Integrin-mediated collagen gel contraction by cardiac fibroblasts: Effects of angiotensin II
84. Left ventricular hypertrophy in ascending aortic stenosis mice: Anoikis and the progression to early failure
85. 1 integrin in the transition from cardiac hypertrophy to failure
86. Integrins and anoikis
87. Membrane protein secretases
88. Metalloprotease-disintegrins: Modular proteins capable of promoting cell-cell interactions and triggering signals by protein-ectodomain shedding
89. An essential role for ectodomain shedding in mammalian development
90. A role for focal adhesion kinase in phenylephrine-induced hypertrophy of rat ventricular cardiomyocytes
91. Endothelin-induced cardiac myocyte hypertrophy: Role for focal adhesion kinase
92. Outside-in signalling of fibronectin stimulates cardiomyocyte hypertrophy in cultured neonatal rat ventricular myocytes
93. FAK) in cultured rat cardiac myocytes
94. Extracellular signal-regulated kinase and c-Jun NH2-terminal kinase activation by mechanical stretch is integrin-dependent and matrix-specific in rat cardiac fibroblasts
95. Early activation of the multicomponent signaling complex associated with focal adhesion kinase induced by pressure overload in the rat heart
96. Disruption of integrin function in the murine myocardium leads to perinatal lethality, fibrosis and abnormal cardiac performance
97. Differential activation of p70 and p85 S6 kinase isoforms during cardiac hypertrophy in the adult mammal
98. Integrin activation and focal complex formation in cardiac hypertrophy
99. "Inside-out" signal transduction inhibited by isolated integrin cytoplasmic domains
100. 5-integrin results in perinatal lethality
101. Altered focal adhesion regulation correlates with cardiomyopathy in mice expressing constitutively active racl
102. Crystal structure of the A domain from the alpha subunit of integrin CR3 (CD11b/CD18)