Versican V1 Proteolysis in Human Aorta in Vivo Occurs at the Glu 441-Ala442 Bond, a Site That Is Cleaved by Recombinant ADAMTS-1 and ADAMTS-4

Journal of Biological Chemistry

Volumn 276, Issue 16, 2001, Pages 13372-13378

  Sandy, John D ^a   Westling, Jennifer ^a   Kenagy, Richard D ^b   Iruela Arispe, M Luisa ^c   Verscharen, Christie ^a   Rodriguez Mazaneque, Juan Carlos ^c   Zimmermann, Dieter R ^d   Lemire, Joan M ^b   Fischer, Jens W ^b   Wight, Thomas N ^b   Clowes, Alexander W ^b  

^a SHRINERS HOSPITALS FOR CHILDREN   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYMES; GENETIC ENGINEERING; SUBSTRATES;

HUMAN AORTA; PROTEOLYSIS;

BIOCHEMISTRY;

A DISINTEGRIN LIKE AND METALLOPROTEASE WITH THROMBOSPONDIN TYPE 1; A DISINTEGRIN LIKE AND METALLOPROTEASE WITH THROMBOSPONDIN TYPE 4; ALANINE; BREVICAN; GLUTAMINE; METALLOPROTEINASE; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; VERSICAN; VERSICAN V1; ADAM PROTEIN; ADAMTS1 PROTEIN, HUMAN; AGGRECANASE 1; AGGRECANASE-1; CSPG2 PROTEIN, HUMAN; DISINTEGRIN; GLUTAMIC ACID; LECTIN; PEPTIDE FRAGMENT; PROCOLLAGEN N PROTEINASE; PROTEOCHONDROITIN SULFATE; PROTEOGLYCAN;

AMINO ACID SEQUENCE; AORTA; AORTA INTIMA; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; IN VIVO STUDY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN LOCALIZATION; WESTERN BLOTTING; ABDOMINAL AORTA; CELL CULTURE; CHEMISTRY; ENZYME SPECIFICITY; INTIMA; METABOLISM; MOLECULAR GENETICS; VASCULAR SMOOTH MUSCLE;

ADAM PROTEINS; ALANINE; AORTA, ABDOMINAL; CELLS, CULTURED; DISINTEGRINS; GLUTAMIC ACID; HUMANS; LECTINS, C-TYPE; METALLOENDOPEPTIDASES; MOLECULAR SEQUENCE DATA; MUSCLE, SMOOTH, VASCULAR; PEPTIDE FRAGMENTS; PROCOLLAGEN N-ENDOPEPTIDASE; PROTEOCHONDROITIN SULFATES; PROTEOGLYCANS; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY; TUNICA INTIMA; VERSICANS;

EID: 0035918194     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M009737200     Document Type: Article

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