Secreted protein acidic and rich in cysteine (SPARC) in patients with diabetic nephropathy and tubulointerstitial injury [1]

Diabetologia

Volumn 43, Issue 8, 2000, Pages 1076-1077

  Kanauchi, M ^a   Nishioka, M ^a   Dohi, K ^a  

^a NARA MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 1; OSTEONECTIN; TRANSFORMING GROWTH FACTOR BETA;

CELL MIGRATION; CELL PROLIFERATION; DIABETIC NEPHROPATHY; EXTRACELLULAR MATRIX; FIBROBLAST; HUMAN; LETTER; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL;

AGED; BIOLOGICAL MARKERS; DIABETIC NEPHROPATHIES; DISEASE PROGRESSION; HUMANS; KIDNEY GLOMERULUS; KIDNEY TUBULES; MIDDLE AGED; OSTEONECTIN;

EID: 0033838265     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001250051493     Document Type: Letter

References (8)

1. The tubulointerstitium in progressive diabetic kidney disease
2. Regulation of vascular morphogenesis by the matricellular protein SPARC
3. SPARC gene expression is reduced in early diabetes-related kidney growth
4. SPARC is expressed in renal interstitial fibrosis and in renal vascular injury
5. Osteonectine/SPARC regulates cellular secretion rates of fibronectin and laminin extracellular matrix proteins
6. Quantification of glomerular TGF-beta1 mRNA in patients with diabetes mellitus
7. Induction of TGF-betal by the matricellular protein SPARC in a rat model of glomerulonephritis
8. SPARC, a secreted protein associated with morphogenesis and tissue remodelling, induces expression of metalloproteinases in fibroblasts through a novel extracellular matrix-dependent pathway