Origins of Obsessive-Compulsive Disorder: Developmental and Evolutionary Perspectives

Developmental Psychopathology: Second Edition

Volumn 3, Issue , 2006, Pages 404-435

  Evans, David W ^a   Leckman, James F ^b  

^a BUCKNELL UNIVERSITY   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Family genetic studies; Neurobiological mechanisms; Neuropsychological components of OCD; Obsessive compulsive behaviors; Obsessive Compulsive Disorder; Obsessive compulsive personality disorder; Obsessive compulsive spectrum disorders

Indexed keywords

EID: 84983579930     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470939406.ch10     Document Type: Chapter

References (264)

1. Abbruzzese, M. B., Ferri, S., & Carcone, S. (1995). Wisconsin Card Sorting Test performance in obsessive-compulsive disorder: No evidence for involvement of dorsolateral prefrontal cortex. Psychiatry Research, 58, 37-43.
2. Alcais, A., & Abel, L. (1999). Maximum-likelihood-binomial method for genetic model-free linkage analysis of quantitative traits in sibships. Genetic Epidemiology, 17, 102-117.
3. Alsobrook, J. P., II, Leckman, J. F., Goodman, W. K., Rasmussen, S. A., & Pauls, D. L. (1999). Segregation analysis of obsessive-compulsive disorder using symptom-based factor scores. American Journal of Medical Genetics, Neuropsychiatric Genetics, 88, 669-675.
4. Altemus, M., Pigott, T., Kalogeras, K. T., Demitrack, M., Dubbert, B., Murphy, D. L., et al. (1992). Abnormalities in the regulation of vasopressin and corticotrophin releasing factor secretion in obsessivecompulsive disorder. Archives of General Psychiatry, 49, 9-20.
5. American Psychiatric Association. (1994). Diagnostic and statistical manual of mental disorders (4th ed.). Washington, DC: Author.
6. American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders (4th ed., text rev.). Washington, DC: Author.
7. Anderson, S. W., Bechara, A., Damasio, H., Tranel, D., & Damasio, A. R. (1999). Impairment of social and moral behaviour related to early damage in human prefrontal cortex. Nature Neuroscience, 2, 1032-1037.
8. Ansseau, M., Legros, J. J., Mormont, C., Cerfontaine, J., Papart, P., Genen, V., et al. (1987). Intranasal oxytocin in obsessive-compulsive disorder. Psychoneuroendocrinology, 1, 231-236.
9. Apter, A., Pauls, D., Bleich, A., Zohar, A. H., Kron, S., Ratzoni, G., et al. (1993). An epidemiologic study of Gilles de la Tourette's syndrome in Israel. Archives of General Psychiatry, 50(9), 734-738.
10. Baer, L. (1993). Factor analysis of symptom subtypes of obsessivecompulsive disorder and their relation to personality and tics. Journal of Clinical Psychiatry, 55(Suppl. 3), 18-23.
11. Baer, L. (1994). Factor analysis of symptom subtypes of obsessivecompulsive disorder and their relation to personality and tic disorders. Journal of Clinical Psychiatry, 55, 18-23.
12. Baer, L., & Minichiello, W. E. (1998). Behavior therapy for obsessivecompulsive disorder. In M. A. Jenike, L. Baer, & W. E. Minichiello (Eds.), Obsessive-compulsive disorders: Practical management (pp. 337-367). St. Louis, MO: Mosby.
13. Baldwin, J. W. (1902). Development and evolution. New York: Macmillan.
14. Barlow, D., DiNardo, P. A., Vermilyea, B., Vermilyea, J., & Blanchard, E. B. (1986). Co-morbidity and depression among the anxiety disorders: Issues in diagnosis and classification. Journal of Nervous and Mental Diseases, 174, 63-72.
15. Baron-Cohen, S. (1988). Do children with Autism have obsessions and compulsions? British Journal of Clinical Psychology, 28, 193-200.
16. Barton, R. (1965). Diabetes insipidus and obsessional neurosis: A syndrome. Lancet, 1(7377), 133-135.
17. Baxter, L. R. (1990). Brain imaging as a tool in establishing a theory of brain pathology in obsessive-compulsive disorder. Journal of Clinical Psychiatry, 51, 22-25.
18. Baxter, L. R., Jr., Phelps, M. E., Mazziotta, J. C., Guze, B. H., Schwartz, J. M., & Selin, C. E. (1987). Local cerebral glucose metabolic rates in obsessive-compulsive disorder. A comparison with rates in unipolar depression and in normal controls. Archives of General Psychiatry, 44, 211-218.
19. Baxter, L. R., Schwartz, J. M., Bergman, K. S., Szuba, M. P., Guze, B. H., Mazziotta, J. C., et al. (1992). Caudate glucose metabolic rate changes with both drug and behavior therapy for obsessive-compulsive disorder. Archives of General Psychiatry, 49, 681-689.
20. Bechara, A., Damasio, H., & Damasio, A. R. (2000). Emotion, decision making and the orbitofrontal cortex. Cerebral Cortex, 10(3), 295-307.
21. Bechara, A., Damasio, A. R., Damasio, H., & Anderson, S. W. (1994). Insensitivity to future consequences following damage to human prefrontal cortex. Cognition, 50, 7-15.
22. Behar, D., Rapoport, J. L., Berg, C., Denckla, M. B., Mann, L., Cox, C., et al. (1984). Computerized tomography and neuropsychological test measures in children with obsessive-compulsive disorder. American Journal of Psychiatry, 141, 363.
23. Berg, C. A., Whitaker, A., Davies, M., Flament, M. F., & Rapoport, J. L. (1988). The survey form of the Leyton Obsessional Inventory-Child Version: Norms from an epidemiological study. Journal of the American Academy of Child and Adolescent Psychiatry, 28, 528-533.
24. Berrios, G. E. (1996). The history of mental symptoms: Descriptive psychopathology since the nineteenth century. Cambridge, UK: Cambridge University Press.
25. Bienvenu, O. J., Samuels, J. F., Riddle, M. A., Hoehn-Saric, R., Liang, K., Cullen, B. A., et al. (2000). The relationship of obsessive-compulsive disorder to possible spectrum disorders: Results from a family study. Biological Psychiatry, 48, 287-293.
26. Billett, E. A., Richter, M. A., & Kennedy, J. L. (1998). Genetics of obsessive-compulsive disorder. In R. P. Swinson, M. M. Anthony, S. Rachman, & M. A. Richter (Eds.), Obsessive-compulsive disorder: Theory, research, and treatment (pp. 181-206). New York: Guilford Press.
27. Black, D. W., Monahan, P., Gable, J., Blum, N., Clancy, G., & Baker, P. (1998). Hoarding and treatment response in 38 nondepressed subjects with obsessive-compulsive disorder. Journal of Clinical Psychiatry, 59, 420-425.
28. Blurton-Jones, N. (1972). Ethological studies of child behavior. New York: Cambridge University Press.
29. Bokura, H., Yamaguchi, S., & Kobayashi, S. (2001). Electrophysiological correlates for response inhibition in a go/no go task. Clinical Neurophysiology, 112(12), 2224-2232.
30. Bolton, D., Dearsley, P., Madronal-Luque, R., & Baron-Cohen, S. (2002). Magical thinking in childhood and adolescence: Development and relation to obsessive compulsion. British Journal of Developmental Psychology, 20(4), 479-494.
31. Botstein, D., & Risch, N. (2003). Discovering genotypes underlying human phenotypes: Past successes for Mendelian disease, future approaches for complex disease. Nature Genetics, 33(Suppl.), 228-237.
32. Botvinick, M., Nystrom, L. E., Fissell, K., Carter, C. S., & Cohen, J. D. (1999). Conflict monitoring versus selection-for-action in anterior cingulate cortex. Nature, 402(6758), 179-181.
33. Bowlby, J. (1969). Attachment and loss: Vol. 1. Attachment. New York: Basic Books.
34. Bowlby, J. (1973). Attachment and loss: Vol. 2. Separation, anxiety and anger. New York: Basic Books.
35. Bradshaw, J. L., & Sheppard, D. M. (2000). The neurodevelopmental frontostriatal disorders: Evolutionary adaptiveness and anomalous lateralization. Brain and Language, 73(2), 297-320.
36. Breiter, H. C., & Rauch, S. L. (1996). Functional MRI and the study of OCD: From symptom provocation to cognitive-behavioral probes of cortico-striatal systems and the amygdala. Neuroimage, 4(Suppl. 3, Pt. 3), S127-S138.
37. Breiter, H. C., Rauch, S. L., Kwong, K. K., Baker, J. R., Weisskoff, R. M., Kennedy, D. N., et al. (1996). Functional magnetic resonance imaging of symptom provocation in obsessive-compulsive disorder. Archives of General Psychiatry, 53(7), 595-606.
38. Bretherton, I. (1987). New perspectives on attachment relations: Security, communication, and internal working models. In J. D. Osofsky (Ed.), Handbook of infant development (pp. 1061-1100). New York: Wiley.
39. Buttolph, M. L., Peets, K. E., & Holland, A. D. (1998). Obsessivecompulsive symptoms and medication treatment in pregnancy. In M. A. Jenike, L. Baer, & W. E. Minichiello (Eds.), Obsessive-compulsive disorders: Practical management (pp. 84-96). St. Louis, MO: Mosby.
40. Carter, A., Pauls, D., & Leckman, J. F. (1996). The developmental of obsessionality: Continuities and discontinuities. In D. Cicchetti & D. Cohen (Eds.), The handbook of developmental psychopathology: Vol. 2. Risk, disorder and adaptation (pp. 9609-9632). New York: Wiley.
41. Carter, A., Pauls, D., Leckman, J. F., & Cohen, D. J. (1994). A prospective longitudinal study of Gilles de la Tourette's syndrome. Journal of the American Academy of Child and Adolescent Psychiatry, 33(3), 377-385.
42. Carter, C. S. (1992). Oxytocin and sexual behavior. Neuroscience and Biobehavioral Review, 16, 131-144.
43. Carter, C. S., DeVries, A. C., & Taymans, S. E. (1997). Peptides, steroids, and pair bonding. Annals of the New York Academy of Sciences, 807, 260-272.
44. Carter, C. S., Macdonald, A. M., Botvinick, M., Ross, L. L., Stenger, V. A., Noll, D., et al. (2000). Parsing executive processes: Strategic vs. evaluative functions of the anterior cingulate cortex. Proceedings of the National Academy of Sciences, USA, 97(4), 1944-1948.
45. Cavallini, M. C., Di Bella, D., Siliprandi, F., Malchiodi, F., & Bellodi, L. (2002). Exploratory factor analysis of obsessive-compulsive patients and association with 5-HTTLPR polymorphism. American Journal of Medical Genetics, Neuropsychiatric Genetics, 114(3), 347-353.
46. Cavedini, P., Ferri, S., Sarcone, S., & Bellodi, L. (1998). Frontal lobes dysfunction in obsessive-compulsive disorder and major depression: A clinical-neuropsychological study. Psychiatric Research, 78, 21.
47. Christensen, K. J., Hadzi-Pavlovic, D., Andrews, G., & Matrick, R. P. (1987). Behavior therapy and tricyclic medication in the treatment of obsessive-compulsive disorder: A quantitative review. Journal of Consulting and Clinical Psychology, 55, 701-711.
48. Cicchetti, D. (1993). Developmental psychopathology: Reactions, ref lections, and projections. Developmental Review, 13, 471-502.
49. Cicchetti, D., & Cohen, D. (Eds.). (1995a). Developmental psychopathology: Vol. 1. Theory and methods. New York: Wiley.
50. Cicchetti, D., & Cohen, D. (Eds.). (1995b). Developmental psychopathology: Vol. 2. Risk, disorder, and adaptation. New York: Wiley.
51. Claude, H., Bourk, H., & Lamache, A. (1927). Obsessive-impulsions consecutives à l'encéphalite épidémique. Encéphale, 22, 716-722.
52. Cohen, L. J., Stein, D. J., Simeon, D., Spadaccini, E., Rosen, J., Aronowitz, B., et al. (1995). Clinical profile, comorbidity, and treatment history in 123 hair pullers: A survey study. Journal of Clinical Psychiatry, 56, 319-326.
53. Corsini, C. A., & Viazzo, P. (1997). The decline of infant and child mortality: The European experience, 1750-1990. The Hague, The Netherlands: Kluwer Law International.
54. Cosyns, P., Gabriels, L., & Nuttin, B. (2003). Deep brain stimulation in treatment refractory obsessive compulsive disorder. Verh K Acad Geneeskd Belg, 65(6), 385-399.
55. Cottraux, J., Note, I., Yao, S. N., Lafont, S., Note, B., Mollard, E., et al. (2001). A randomized controlled trial of cognitive therapy versus intensive behavior therapy in obsessive-compulsive disorder. Psychotherapy and Psychosomatics, 70(6), 288-297.
56. Cowan, C. P., & Cowan, P. A. (1992). When partners become parents. New York: Basic Books.
57. Cox, C. S. (1997). Neuropsychological abnormalities in obsessivecompulsive disorder and their assessments. International Review of Psychiatry, 9, 45-59.
58. Cox, C. S., Fedio, P., & Rapoport, J. L. (1989). Neuropsychological testing of obsessive-compulsive adolescents. In J. L. Rapoport (Ed.), Obsessive-compulsive disorder in children and adolescents (pp. 73-85). Washington, DC: American Psychiatric Press.
59. Darwin, C. (1872). The expression of emotions in man and animals. London: Murray.
60. Darwin, C. (1993). The origin of species. New York: Modern Library. (Original work published 1859)
61. Davidson, R. J., & Irwin, W. (1999). The functional neuroanatomy of emotion and affective style. Trends in Cognitive Science, 3(1), 11-21.
62. de Boer, J. A., & Westenberg, H. G. M. (1992). Oxytocin in obsessivecompulsive disorder. Peptides, 13, 1083-1085.
63. Depue, R. A., & Collins, P. F. (1999). Neurobiology of the structure of personality: Dopamine, facilitation of incentive motivation, and extraversion. Behavioral and Brain Sciences, 22(3), 491-569.
64. Diamond, A. (1988). Abilities and neural mechanisms underlying AB performance. Child-Development, 59(2), 523-527.
65. Diamond, A., & Taylor, C. (1996). Development of an aspect of executive control: Development of the abilities to remember what I said and to "Do as I say, not as I do." Developmental Psychobiology, 29(4), 4-315.
66. Dodman, N. H. (1998). Veterinary models of obsessive-compulsive disorder. In M. A. Jenike, L. Baer, & W. E. Minichiello (Eds.), Obsessivecompulsive disorders: Practical management (pp. 318-334). St. Louis, MO: Mosby.
67. Ekman, P. E. (1980). The face of man. New York: Garland STPM Press.
68. Elston, R. C., Buxbaum, S., Jacobs, K. B., & Olson, J. M. (2000). Haseman and Elston revisited. Genetic Epidemiology, 19, 1-17.
69. Emmelkamp, P. M. G. (1982). Phobic and obsessive-compulsive disorders: Theory research, and practice. New York: Plenum Press.
70. Erikson, E. H. (1968). Identity: Youth and crisis. London: Faber & Faber.
71. Evans,D.W. (2000). Rituals and other syncretic tools: Insights fromWerner's comparative psychology. Journal of AdultDevelopment, 7, 49-61.
72. Evans, D. W., Gray, F. L., & Leckman, J. F. (1999). Rituals, fears and phobias: Insights from development, psychopathology and neurobiology. Child Psychiatry and Human Development, 29, 261-276.
73. Evans, D. W., Leckman, J. F., Carter, A., Reznick, J. S., Henshaw, D., King, R. A., et al. (1997). Ritual, habit and perfectionism: The prevalence and development of compulsive-like behaviors in normal young children. Child Development, 68, 58-68.
74. Evans, D. W., Lewis, M. D., & Iobst, E. (2004). The role of the orbitofrontal cortex in normally developing compulsive-like behaviors and obsessive-compulsive disorder. Brain and Cognition, 55, 220-234.
75. Evans, D. W., Milanak, M., Medeiros, B., & Ross, J. (2002). Magical beliefs and rituals in young children. Child Psychiatry and Human Development, 33, 43-58.
76. Fahrbach, S. E., Morrell, J. I., & Pfaff, D. W. (1985). Possible role for endogenous oxytocin in estrogen-facilitated maternal behavior in rats. Neuroendocrinology, 40(6), 526-532.
77. Fals-Stewart, W. (1992). A dimensional analysis of the Yale-Brown Obsessive Compulsive Scale. Psychological Reports, 70, 238-240.
78. Fiske, A. P., & Haslam, N. (1997). Is obsessive-compulsive disorder a pathology of the human disposition to perform socially meaningful rituals? Evidence of similar content. Journal of Nervous and Mental Diseases, 185(4), 211-222.
79. Flament, M. F., Koby, E., Rapoport, J. L., Berg, C. J., Zahn, T., Cox, C., et al. (1990). Childhood obsessive-compulsive disorder: A prospective follow-up study. Journal of Child Psychology and Psychiatry, 31, 363-380.
80. Flament, M. F., Whitaker, A., Rapoport, J. L., Davies, M., Zarembabere, C., Kalikow, K., et al. (1988). Obsessive compulsive disorder in adolescence: An epidemiologic study. Journal of the American Academy of Child and Adolescent Psychiatry, 27, 764-771.
81. Foa, E. B., & Goldstein, A. (1978). Continuous exposure and complete response prevention in the treatment of obsessive-compulsive neurosis. Behavioral Research and Therapy, 9, 821-829.
82. Francis, G., & Gragg, R. T. (1996). Childhood obsessive compulsive disorder. In A. Kazdin (Ed.), Developmental clinical psychology and psychiatry (p. 35). Thousand Oaks, CA: Sage.
83. Freeston, M. H., Ladouceur, R., Thibodeau, N., & Gagnon, F. (1991). Cognitive intrusions in a non-clinical population: Pt. I. Response style, subjective experience, and appraisal. Behavioral Research and Therapy, 29, 233-248.
84. Freud, S. (1919). The problem of anxiety. New York: Norton.
85. Freud, S. (1966). Notes upon the case of obsessional neurosis. In J. Stratchey (Ed.), Standard edition of the complete psychological works of Sigmund Freud, 12, 311--26. London: Hogarth Press. (Original work published 1909)
86. Galderisi, S., Mucci, A., Catapano, F., D'Amato, A. C., & Maj, M. (1995). Neuropsychological slowness in obsessive-compulsive patients: Is it confined to tests involving the fronto-subcortical systems? British Journal of Psychiatry, 167, 394-398.
87. Gehring, W. J., Himle, J., & Nisenson, L. G. (2000). Action monitoring dysfunction in obsessive-compulsive disorder. Psychological Science, 11, 1-6.
88. Geller, D., Biederman, J., Jones, J., Park, K., Schwartz, S., Shapiro, S., et al. (1998). Is juvenile obsessive-compulsive disorder a developmental subtype of the disorder? A review of the pediatric literature. Journal of the American Academy of Child and Adolescent Psychiatry, 37, 420-427.
89. Gesell, A. (1928). Infancy and human growth. New York: Macmillan.
90. Gesell, A., Ames, L. B., & Ilg, F. L. (1974). Infant and the child in the culture today. New York: Harper & Row.
91. Goldberg, S., & DiVitto, B. (1995). Parenting children born preterm. In M. Bornstein (Ed.), Handbook of parenting (Vol. 1, pp. 209-231). Mahwah, NJ: Erlbaum.
92. Goodman, W. K., McDougle, C. J., Price, L. H., Riddle, M. A., Pauls, D. L., & Leckman, J. F. (1990). Beyond the serotonin hypothesis: A role for dopamine in some forms of obsessive compulsive disorder? Journal of Clinical Psychiatry, 51, 36-43.
93. Goodman, W. K., Price, L. H., Rasmussen, S. A., Delgado, P. L., Heninger, G. R., & Charney, D. S. (1989). Efficacy of f luvoxamine in obsessive-compulsive disorder: A double-blind comparison with placebo. Archives of General Psychiatry, 46, 36-44.
94. Goodman, W. K., Price, L. H., Rasmussen, S. A., Mazure, C., Delgado, P., Heninger, G. R., et al. (1989). The Yale-Brown Obsessive Compulsive Scale: Pt. II. Validity. Archives of General Psychiatry, 46, 1012-1016.
95. Goodman, W. K., Price, L. H., Rasmussen, S. A., Mazure, C., Fleischmann, R. L., Hill, C. L., et al. (1989). The Yale-Brown Obsessive Compulsive Scale: Pt. I. Development, use and reliability. Archives of General Psychiatry, 46, 1006-1011.
96. Goodman, W. K., Ward, H., Kablinger, A., & Murphy, T. (1997). Fluvoxamine in the treatment of obsessive-compulsive disorder and related conditions. Journal of Clinical Psychiatry, 58, 32-49.
97. Goodwin, D. W., Guze, S. B., & Robins, E. (1969). Follow-up studies in obsessional neuroses. Archives of General Psychiatry, 20, 182-187.
98. Gottesman, I. I., & Gould, T. D. (2003). The endophenotype concept in psychiatry: Etymology and strategic intentions. American Journal of Psychiatry, 160(4), 636-645.
99. Grados, M. A., Riddle, M. A., Samuels, J. F., Liang, K. Y., Hoehn-Saric, R., Bienvenu, O. J., et al. (2001). The familial phenotype of obsessive-compulsive disorder in relation to tic disorders: The Hopkins OCD family study. Biological Psychiatry, 50(8), 559-565.
100. Grau, A. (1991). Estudio neuropsicologico sle trastorno obsesivocompulsivo. (Primera parte). Revista de Psiquiatria de la facultdad se Medicina de Barcelona, 18, 11-22.
101. Greer, J. M., & Capecchi, M. R. (2002). Hoxb8 is required for normal grooming behavior in mice. Neuron, 33, 23-34.
102. Gross-Isseroff, R., Sasson, Y., Voet, H., Hendler, T., Luca-Haimovici, K., Kandel-Sussman, H., et al. (1996). Alternation learning in obsessive-compulsive disorder. Biological Psychiatry, 39(8), 733-738.
103. Gu, C., Province, M., Todorov, A., & Rao, D. C. (1998). Meta-analysis methodology for combining non-parametric sibpair linkage results: Genetic homogeneity and identical markers. Genetic Epidemiology, 15, 609-626.
104. Halmi, K. A., Sunday, S. R., Klump, K., Strober, M., Leckman, J. F., Fichter, M., et al. (2003). Obsessions and compulsions in anorexia nervosa subtypes. International Eating Disorders Journal, 33(3), 308-319.
105. Hanna, G. L., McCracken, J. T., & Cantwell, D. P. (1991). Prolactin in childhood obsessive-compulsive disorder: Clinical correlates and response to clomipramine. Journal of the American Academy of Child and Adolescent Psychiatry, 30, 173-178.
106. Hanna, G. L., Veenstra-VanderWeele, J., Cox, N. J., Boehnke, M., Himle, J. A., Curtis, G. C., et al. (2002, July). Genome-wide linkage analysis of families with obsessive-compulsive disorder ascertained through pediatric probands. American Journal of Medical Genetics, 114(5), 7.
107. Head, D., Bolton, D., & Hymas, N. (1989). Deficit in cognitive shifting ability and obsessive-compulsive disorder. Biological Psychiatry, 25, 929-937.
108. Hinde, R. A. (1974). Biological bases of human social behavior. New York: McGraw-Hill.
109. Hodapp, R. M. (1995). Parenting children with Down syndrome and other types of mental retardation. In M. Bornstein (Ed.), Handbook of parenting (Vol. 1, pp. 233-253). Mahwah, NJ: Erlbaum.
110. Hodgson, R. J., & Rachman, S. (1977). Obsessional-compulsive complaints. Behavioral Research and Therapy, 15 389-395.
111. Hofer, M. A. (1995). An evolutionary perspective on anxiety. In R. A. Glick & S. Roose (Eds.), Anxiety as symptom and signal (pp. 17-38). Hillsdale, NJ: Analytic Press.
112. Hollander, E. (1993). Obsessive-compulsive spectrum disorders: An overview. Psychiatric Annals, 23, 355-358.
113. Hollander, E. (1998). Treatment of obsessive-compulsive spectrum disorders with SSRIs. British Journal of Psychiatry, 173(Suppl. 35), 7-12.
114. Hollander, E., & Wong, C. M. (1995). Obsessive-compulsive spectrum disorders. Journal of Clinical Psychiatry, 56(Suppl. 4), 3-6.
115. Hymas, N., Lees, A., Bolton, D., Epps, K., & Head, D. (1991). The neurology of obsessional slowness. Brain, 114, 2203-2233.
116. Ingram, I. M. (1961). Obsessional illness in mental hospital patients. Journal of Mental Science, 107, 380-402.
117. Insel, T. R. (1992). Toward a neuroanatomy of obsessive-compulsive disorder. Archives of General Psychiatry, 49, 739-744.
118. Insel, T. R., & Harbaugh, C. R. (1989). Lesions of the hypothalamus paraventicular nucleus disrupt the initiation of maternal behavior. Physiology and Behavior, 45, 1033-1041.
119. Insel, T. R., & Pickar, D. (1983). Naloxone administration in obsessivecompulsive disorder: Report of two cases. American Journal of Psychiatry, 140, 1219-1220.
120. Insel, T. R., & Young, L. J. (2001). The neurobiology of attachment. Nature Reviews Neuroscience, 2(2), 129-136.
121. Janet, P., & Raymond, F. (1976). Les obsessions et la psychastenie (Vol. I ). New York: Arno Press. (Original work published in 1903)
122. Jenike, M. A. (1998). Theories of etiology. In M. A. Jenike, L. Baer, & W. E. Minichiello (Eds.), Obsessive-compulsive disorders: Practical management (pp. 203-221). St. Louis, MO: Mosby.
123. Jenike, M. A., Baer, L., Ballantine, T., Martuza, R. L., Tynes, S., Giriunas, I., et al. (1991). Cingulotomy for refractory obsessive-compulsive disorder. A long-term follow-up of 33 patients. Archives of General Psychiatry, 48(6), 548-555.
124. Jenike, M. A., & Wilhelm, S. (1998). Illnesses related to obsessivecompulsive disorder. In M. A. Jenike, L. Baer, & W. E. Minichiello (Eds.), Obsessive-compulsive disorders: Practical management (pp. 121-142). St. Louis, MO: Mosby.
125. Jones, A., Cho, R., Nystrom, L., Cohen, J., & Braver, T. (2002). A computational model of anterior cingulate function in speeded response tasks: Effects of frequency, sequence, and conflict. Cognitive Af fective and Behavioral Neuroscience, 2(4), 300-317.
126. Kagan, J. (1981). The second year: The emergence of self-awareness. Cambridge, MA: Harvard University Press.
127. Karno, M., Golding, J. M., Sorenson, S. B., & Burnam, M. A. (1988). The epidemiology of obsessive-compulsive disorder in five U.S. communities. Archives of General Psychiatry, 45, 1094-1099.
128. Kim, S. W., Dysken, M. W., Pheley, A. M., & Hoover, K. M. (1994). The Yale-Brown Obsessive-Compulsive Scale: Measures of internal consistency. Psychiatry Research, 51, 203-211.
129. King, R. A., Leckman, J. F., Scahill, L. D., & Cohen, D. J. (1998). Obsessive-compulsive disorder, anxiety, and depression. In J. F. Leckman & D. J. Cohen (Eds.), Tourette's syndrome-Tics, obsessions, compulsions: Developmental psychopathology and clinical care (pp. 43-62). New York: Wiley.
130. Knight, C. C. (1972). Bifrontal stereotaxic tractotomy in the substantia innominata: An experience of 450 cases. In E. Hitchcock, L. Laitinen, & K. Vaernet (Eds.), Psychosurgery (pp. 267-277). Springfield, IL: Charles C. Thomas.
131. Konner, M. (1976). Maternal care, infant behavior and development among the !Kung. In R. Lee & I. DeVore (Eds.), Kalahari hunter gathers: Studies of the !Kung San and their neighbors (pp. 377-394). Cambridge, MA: Harvard University Press.
132. Laplane, D., Levasseur, M., Pillon, B., Dubois, B., Baulac, M., Mazoyer, B., et al. (1989). Obsessive-compulsive and other behavioural changes with bilateral basal ganglia lesions. A neuropsychological, magnetic resonance imaging and positron tomography study. Brain, 112, 699-725.
133. Last, C. G., Perrin, S., Hersen, M., & Kazdin, A. E. (1992). A prospective study of childhood anxiety disorders. Journal of the American Academy of Child and Adolescent Psychiatry, 35(11), 1502-1510.
134. Leckman, J. F., Goodman, W. K., North, W. G., Chappell, P. B., Price, L. H., Pauls, D. L., et al. (1994a). Elevated levels of CSF oxytocin in obsessive compulsive disorder: Comparison with Tourette's syndrome and healthy controls. Archives of General Psychiatry, 51, 782-792.
135. Leckman, J. F., Goodman, W. K., North, W. G., Chappell, P. B., Price, L. H., Pauls, D. L., et al. (1994b). The role of oxytocin in obsessivecompulsive disorder and related normal behavior. Psychoneuroendocrinology, 9, 723-749.
136. Leckman, J. F., Grice, D. E., Barr, L. C., deVries, A. L. C., Martin, C., Cohen, D. J., et al. (1995). Tic-related vs. non-tic related obsessive compulsive disorder. Anxiety, 1, 208-215.
137. Leckman, J. F., Grice, D. E., Boardman, J., Zhang, H., Vitale, A., Bondi, C., et al. (1997). Symptoms of obsessive-compulsive disorder. American Journal of Psychiatry, 154, 911-917.
138. Leckman, J. F., & Herman, A. (2002). Maternal behavior and developmental psychopathology. Biological Psychiatry, 51(1), 27-43.
139. Leckman, J. F., & Mayes, L. C. (1998). Understanding developmental psychopathology: How useful are evolutionary accounts? Journal of the American Academy of Child and Adolescent Psychiatry, 37(10), 10-1011.
140. Leckman, J. F., & Mayes, L. C. (1999). Preoccupations and behaviors associated with romantic and parental love: The origin of obsessivecompulsive disorder? Child and Adolescent Psychiatric Clinics of North America, 8, 635-665.
141. Leckman, J. F., Mayes, L. C., Feldman, R., Evans, D., King, R. A., & Cohen, D. J. (1999). Early parental preoccupations and behaviors and their possible relationship to the symptoms of obsessive-compulsive disorder. Acta Psychiatrica Scandinavica, 100(Suppl. 396), 1-26.
142. Leckman, J. F., Pauls, D. L., Zhang, H., Rosario-Campos, M. C., Katsovich, L., Kidd, K. K., et al. (2003). Obsessive-compulsive symptom dimensions in affected sibling pairs diagnosed with Gilles de la Tourette syndrome. American Journal of Medical Genetics, 116, 60-68.
143. Leckman, J. F., Zhang, H., Alsobrook, J. P., & Pauls, D. L. (2001). Symptom dimensions in obsessive-compulsive disorder: Toward quantitative phenotypes. American Journal of Medical Genetics, 105(1), 28-30.
144. Lenane, M. C., Swedo, S. E., Rapoport, J. L., Leonard, H., Sceery, W., & Guroff, J. J. (1992). Rates of obsessive-compulsive disorder in the first-degree relatives of patients with trichotillomania. Journal of Child Psychology and Psychiatry, 33, 925-933.
145. Leonard, H. L., Goldberger, E. L., Rapoport, J. L., Cheslow, B. S., & Swedo, S. (1990). Childhood rituals: Normal development or obsessive-compulsive symptoms? Journal of the American Academy of Child and Adolescent Psychiatry, 29, 17-23.
146. Leonard, H. L., Swedo, S. E., Lenane, M. C., Rettew, D. C., Hamburger, S. D., Bartko, J. J., et al. (1993). A 2-to 7-year follow-up study of 54 obsessive-compulsive children and adolescents. Archives of General Psychiatry, 50(6), 429-439.
147. Lewis, A. J. (1936). Problems of obsessional illness. Proceedings of the Royal Society of Medicine, 29, 325-336.
148. Lin, H. Q., Yeh, C. B., Peterson, B. S., Scahill, L., Grantz, H., Findley, D., et al. (2002). Assessment of symptom exacerbations in a longitudinal study of children with Tourette syndrome or obsessive-compulsive disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 41, 1070-1077.
149. Lo, W. H. (1967). A follow-up study of obsessional neurotics in Hong Kong Chinese. British Journal of Psychiatry, 113, 823.
150. Lorberbaum, J. P., Newman, J. D., Horwitz, A. R., Dubno, J. R., Lydiard, R. B., Hamner, M. B., et al. (2002). A potential role for thalamocingulate circuitry in human maternal behavior. Biological Psychiatry, 51(6), 431-445.
151. Lucey, L. V., Burness, C. E., Costa, D. C., Gacinovic, S., Pilowsky, L. S., Ell, P. J., et al. (1997). Wisconsin Card Sort Task (WCST) errors and cerebral blood flow in obsessive-compulsive disorder (OCD). British Journal of Medical Psychology, 70, 403-411.
152. Main, M., & Cassidy, J. (1988). Categories of response to reunion with the parent at age six. Developmental Psychology, 24, 415-426.
153. Marks, I. M. (1987). Fears, phobias and rituals. New York: Oxford University Press.
154. Marks, I. M., Lelliott, P., Basoglu, M., Noshirvani, H., Montero, W., & Kasvikis, Y. (1988). Clomipramine, self-exposure and therapist aided exposure in obsessive-compulsive ritualisers. British Journal of Psychiatry, 152, 522-534.
155. Marvin, R. S. (1977). An ethological-cognitive model for the attenuation of mother-child attachment behavior. In T. M. Alloway, L. L. Krames, & P. Pliner (Eds.), Advances in the study of communication and af fect: Vol. 3. Attachment behavior (pp. 25-60). New York: Plenum Press.
156. Marvin, R. S., & Britner, P. A. (1999). Normative development: The ontogeny of attachment. In J. Cassidy & P. R. Shaver (Eds.), Handbook of attachment (pp. 44-67). New York: Guilford Press.
157. Marvin, R. S., & Greenberg, M. T. (1982). Preschoolers' changing conceptions of their mothers: A social-cognitive study of mother-infant attachment. In D. Forbes & M. T. Greenberg (Eds.), New directions in child development: No. 18. Children's planning strategies (pp. 47-60). San Francisco: Jossey-Bass.
158. Mataix-Cols, D., Baer, L., Rauch, S. L., & Jenike, M. A. (2000). Relation of factor-analyzed symptom dimensions of obsessive-compulsive disorder to personality disorders. Acta Psychiatrica Scandinavica, 102, 199-202.
159. Mataix-Cols, D., Cullen, S., Lange, K., Zelaya, F., Andrew, C., Amaro, E., et al. (2003). Neural correlates of anxiety associated with obsessive-compulsive symptom dimensions in normal volunteers. Biological Psychiatry, 53, 482-493.
160. Mataix-Cols, D., Junque, C., Sanchez-Turet, M., Vallejo, J., Verger, K., & Barrios, M. (1999). Neuropsychological functioning in a subclinical obsessive-compulsive sample. Biological Psychiatry, 45(7), 898-904.
161. Mataix-Cols, D., Marks, I. M., Greist, J. H., Kobak, K. A., & Baer, L. (2002). Obsessive-compulsive symptom dimensions as predictors of compliance with and response to behaviour therapy: Results from a controlled trial. Psychotherapy and Psychosomatics, 71(5), 255-262.
162. Mataix-Cols, D., Rauch, S. L., Baer, L., Eisen, J. L., Shera, D. M., Goodman, W. K., et al. (2002). Symptom stability in adult obsessivecompulsive disorder: Data from a naturalistic two-year follow-up study. American Journal of Psychiatry, 159, 263-268.
163. Mataix-Cols, D., Rauch, S. L., Manzo, P. A., Jenike, M. A., & Baer, L. (1999). Use of factor-analyzed symptom dimensions to predict outcome with serotonin reuptake inhibitors and placebo in the treatment of obsessive-compulsive disorder. American Journal of Psychiatry, 156(9), 1409-1416.
164. Mataix-Cols, D., Rosario-Campos, M. C., & Leckman, J. F. (2005). A multidimensional model of obsessive-compulsive disorder. American Journal of Psychiatry, 162, 228-238.
165. Mataix-Cols, D., Wooderson, S., Lawrence, N., Brammer, M. J., Speckens, A., & Phillips, M. L. (2004, June). Distinct neural correlates of washing, checking, and hoarding symptom dimensions in obsessivecompulsive disorder. Archives of General Psychiatry, 61(6), 6-564.
166. McDougle, C. J., Goodman, W. K., Leckman, J. F., Barr, L. C., Heninger, G. R., & Price, L. H. (1993). The efficacy of f luvoxamine in obsessive-compulsive disorder: Effects of comorbid chronic tic disorder. Journal of Clinical Psychopharmacology, 13, 354-358.
167. McDougle, C. J., Goodman, W. K., Leckman, J. F., Lee, N. C., Heninger, G. R., & Price, L. H. (1994). Haloperidol addition in fluvoxaminerefractory obsessive-compulsive disorder: A double blind, placebocontrolled study in patients with and without tics. Archives of General Psychiatry, 51, 302-308.
168. McGuire, P. K., Bench, C. J., Frith, C. D., Marks, I. M., Frackowiak, R. S., & Dolan, R. J. (1994). Functional anatomy of obsessive-compulsive phenomena. British Journal of Psychiatry, 164(4), 459-468.
169. McKay, D., Danyko, S., Neziroglu, F., & Yaryura-Tobias, J. A. (1995). Factor structure of the Yale-Brown Obsessive-Compulsive Scale: A dimensional measure. Behavioral Research and Therapy, 33, 865-869.
170. Meyer, A., & Beck, E. (1954). Prefrontal leucotomy and related operations. London: Oliver & Boyd.
171. Meyer, V., Levy, R., & Schnurer, A. (1974). The behavioral treatment of obsessive-compulsive disorders. In H. R. Beech (Ed.), Obsessional states. London: Methuen.
172. Miguel, E. C., Rauch, S. L., & Jenike, M. A. (1997). Obsessive-compulsive disorder. Psychiatric Clinics of North America, 20, 863-883.
173. Minichiello, W. E., Baer, L., Jenike, M. A., & Holland, A. (1990). Age of onset of major subtypes of obsessive-compulsive disorder. Journal of Anxiety Disorders, 4, 147-150.
174. Mowrer, O. H. (1960). Learning theory and behavior. New York: Wiley.
175. Nemiah, I. (1985). Obsessive-compulsive neurosis. In A. Freedman, H. Kaplan, & B. Sadock (Eds.), A comprehensive textbook of psychiatry (pp. 1241-1255). Baltimore: Williams & Wilkins.
176. Nestadt, G., Samuels, J., Riddle, M., Bienvenu, O. J., III, Liang, K. Y., LaBuda, M., et al. (2000). A family study of obsessive-compulsive disorder. Archives of General Psychiatry, 57(4), 358-363.
177. Neziroglu, F., Anemone, R., & Yaryura-Tobias, J. A. (1992). Onset of obsessive-compulsive disorder in pregnancy. American Journal of Psychiatry, 149, 947-950.
178. Nordahl, T. E., Benkelfat, C., Semple, W., Gross, M., King, A. C., & Cohen, R. M. (1989). Cerebral glucose metabolic rates in obsessivecompulsive disorder. Neuropsychopharmacology, 2, 23-28.
179. Numan, M. (1994). Maternal behavior. In E. Knobil & J. D. Neill (Eds.), The physiology of reproduction (2nd ed.). New York: Raven Press.
180. Obsessive Compulsive Cognitions Working Group. (1997). Cognitive assessment of obsessive-compulsive disorder. Behavior Research and Therapy, 35, 667-681.
181. Ochsner, K. N., Bunge, S. A., Gross, J. J., & Gabrieli, J. D. (2002). Rethinking feelings: An fMRI study of the cognitive regulation of emotion. Journal of Cognitive Neuroscience, 14(8), 1215-1229.
182. O'Sullivan, R. L., Rauch, S. L., Breiter, H. C., Grachev, I. D., Baer, L., Kennedy, D. N., et al. (1997). Reduced basal ganglia volumes in trichotillomania measured via morphometric magnetic resonance imaging. Biological Psychiatry, 42, 39-45.
183. Passman, R. H. (1976). Arousal-reducing properties of attachment objects: Testing the function limits of security blanket relative to the mother. Developmental Psychology, 12, 421-436.
184. Passman, R. H. (1977). Providing attachment objects to facilitate learning and reduce stress: Effects of mother and security blanket. Developmental Psychology, 13, 25-28.
185. Passman, R. H. (1987). Attachment objects: Are children with security blankets insecure? Journal of Consulting and Clinical Psychology, 55, 825-830.
186. Pauls, D. L., Alsobrook, J. P., II, Goodman, W. K., Rasmussen, S., & Leckman, J. F. (1995). A family study of obsessive-compulsive disorder. American Journal of Psychiatry, 152, 76-84.
187. Pauls, D. L., & Leckman, J. F. (1986). The inheritance of Gilles de la Tourette syndrome and associated behaviors: Evidence for autosomal dominant transmission. NewEngland Journal ofMedicine, 315, 993-997.
188. Pauls, D. L., Leckman, J. F., & Cohen, D. J. (1994). Evidence against a genetic relationship between the Gilles de la Tourette syndrome and anxiety, depression, panic and phobic disorders. British Journal of Psychiatry, 164, 215-221.
189. Pedersen, C. A., Caldwell, J. D., Johnson, M. F., Fort, S. A., & Prange, A. J., Jr. (1985). Oxytocin antiserum delays onset of ovarian steroidinduced maternal behavior. Neuropeptides, 6(2), 175-182.
190. Pedersen, C. A., & Prange, A. J., Jr. (1979). Induction of maternal behavior in virgin rats after intracerebroventricular administration of oxytocin. Proceedings of the National Academy of Sciences, USA, 76, 6661-6665.
191. Peterson, B. S., Bronen, R. A., & Duncan, C. C. (1996). Three cases of symptom change in Tourette's syndrome and obsessive-compulsive disorder associated with paediatric cerebral malignancies. Journal of Neurology, Neurosurgery, and Psychiatry, 61(5), 497-505.
192. Peterson, B. S., Pine, D. S., Cohen, P., & Brook, J. S. (2001). Prospective, longitudinal study of tic, obsessive-compulsive, and attentiondeficit /hyperactivity disorders in an epidemiological sample. Journal of the American Academy of Child and Adolescent Psychiatry, 40, 685-695.
193. Phillips, K. A. (1996). Pharmacologic treatment of body dysmorphic disorder. Pharmacological Bulletin, 32, 597-605.
194. Phillips, K. A., Gunderson, C. G., Mallya, G., McElroy, S. L., & Carter, W. (1998). A comparison study of body dysmorphic disorder and obsessive-compulsive disorder. Journal of Clinical Psychiatry, 59, 568-575.
195. Phillips, M. L., Marks, I. M., Senior, C., Lythgoe, D., O'Dwyer, A. M., Meehan, O., et al. (2000). A differential neural response in obsessivecompulsive patients with washing compared with checking symptoms to disgust. Psychological Medicine, 30, 1037-1050.
196. Piaget, J. (1962). Play, dreams and imitation in childhood. New York: Norton.
197. Pietrefesa, A., & Evans, D. W. (in press). Children's rituals and executive function: Insights from the neurobiology of obsessive-compulsive disorder. Brain and Cognition.
198. Pitman, R. K. (1987). Pierre Janet on obsessive-compulsive disorder (1903): Review and commentary. Archives of General Psychiatry, 44, 226-232.
199. Pitman, R. K. (1989). Animal models of compulsive behavior. Biological Psychiatry, 26, 189-198.
200. Pitman, R. K. (1991). Historical considerations. In J. Zohar, T. Insel, & S. Rasmussen (Eds.), The psychobiology of obsessive-compulsive disorder (pp. 1-12). New York: Springer.
201. Pollitt, J. (1957). Natural history of obsessional states. British Medical Journal, 26, 194.
202. Rachman, S. J., & de Silva, P. (1978). Abnormal and normal obsessions. Behavior Research and Therapy, 16, 233-248.
203. Rachman, S. J., & Hodgson, R. J. (1980). Obsessions and compulsions. Englewood Cliffs, NJ: Prentice-Hall.
204. Rapoport, J. L. (1989). Summary. In J. L. Rapoport (Ed.), Obsessivecompulsive disorder in children and adolescents (pp. 347-350). Washington, DC: American Psychiatric Press.
205. Rasmussen, S. A. (1994). Obsessive-compulsive spectrum disorders. Journal of Clinical Psychiatry, 55, 89-91.
206. Rasmussen, S. A., & Eisen, J. L. (1991). Phenomenology of OCD: Clinical subtypes, heterogeneity and coexistence. In J. Zohar, T. Insel, & S. Rasmussen (Eds.), The psychobiology of obsessive-compulsive disorder (pp. 13-43). New York: Springer.
207. Rasmussen, S. A., & Eisen, J. L. (1998). Clinical and epidemiological features of obsessive-compulsive disorder. In M. A. Jenike, L. Baer, & W. E. Minichiello (Eds.), Obsessive-compulsive disorders: Practical management (pp. 12-43). St. Louis, MO: Mosby.
208. Rasmussen, S. A., & Tsuang, M. T. (1984). The epidemiology of obsessivecompulsive disorder. Journal of Clinical Psychiatry, 45, 450-457.
209. Rauch, S. L., Dougherty, D. D., Shin, L. M., Alpert, N. M., Manzo, P., Leahy, L., et al. (1998). Neural correlates of factor-analyzed OCD symptom dimensions: A PET study. CNS Spectrums, 3, 37-43.
210. Rauch, S. L., Jenike, M. A., Alpert, N. M., Baer, L., Breiter, H. C., Savage, C. R., et al. (1994). Regional cerebral blood flow measured during symptom provocation in obsessive-compulsive disorder using oxygen 15-labeled carbon dioxide and positron emission tomography. Archives of General Psychiatry, 51, 62-70.
211. Rauch, S. L., Savage, C. R., Alpert, N. M., Dougherty, D., Kendrick, A., Curran, T., et al. (1997). Probing striatal function on obsessive-compulsive disorder: A PET study of implicit sequence learning. Journal of Neuropsychiatry and Clinical Neuroscience, 9, 568-573.
212. Rauch, S. L., Savage, C. R., Alpert, N. M., Fischman, A. J., & Jenike, M. A. (1997). The functional neuroanatomy of anxiety: A study of three disorders using positron emission tomography and symptom provocation. Biological Psychiatry, 42(6), 446-452.
213. Ravindran, A. V., Lapierre, Y. D., & Anisman, H. (1999). Obsessivecompulsive spectrum disorders: Effective treatment with paroxetine. Canadian Journal of Psychiatry, 44, 805-807.
214. Rolls, E. T. (2000). The orbitofrontal cortex and reward. Cerebral Cortex, 10, 284-294.
215. Rosario-Campos, M. C., Leckman, J. F., Curi, M., Quantrano, S., Katsovich, L., Miguel, E. C., et al. (2005). A family study of early-onset obsessive-compulsive disorder. American Journal of Medical Genetics (Neuropsychiatric Genet).
216. Rosario-Campos, M. C., Leckman, J. F., Mercadante, M. T., Shavitt, R. G., Prado, H. S., Sada, P., et al. (2001). Adults with early-onset obsessive-compulsive disorder. American Journal of Psychiatry, 158(11), 1899-1903.
217. Rosario-Campos, M. C., Miguel, E. C., Quantrano, S., Chacon, P., Ferrao, Y., Findley, D., et al. (in press). The Dimensional Yale-Brown Obsessive Compulsive Scale (DY-BOCS): An instrument for assessing obsessive-compulsive symptom dimensions. Manuscript in preparation.
218. Rosenberg, D. R., Averbach, D. H., O'Hearn, K. M., Seymour, A. B., Birmaher, B., & Sweeney, J. A. (1997). Oculomotor response inhibition abnormalities in pediatric obsessive-compulsive disorder. Archives of General Psychiatry, 54, 824.
219. Rosenberg, D. R., Dick, E. L., O'Hearn, K. M., & Sweeney, J. A. (1997). Response inhibition deficits in obsessive-compulsive disorder: An indicator of dysfunction in fronto-striatal circuits. Journal of Psychiatric Neuroscience, 22, 29-38.
220. Salkovskis, P. M. (1985). Obsessive-compulsive problems: A cognitivebehavioural analysis. Behavioral Research and Therapy, 23, 571-583.
221. Salkovskis, P. M., & Harrison, J. (1984). Abnormal and normal obsessions: A replication. Behavioral Research and Therapy, 22, 549-552.
222. Samuels, J., Bienvenu, O. J., III, Riddle, M. A., Cullen, B. A., Grados, M. A., Liang, K. Y., et al. (2002). Hoarding in obsessive compulsive disorder: Results from a case-control study. Behavioral Research and Therapy, 40, 517-528.
223. Santosh, P. J. (2000). Neuroimaging in child and adolescent psychiatric disorders. Archives of the Diseases of Children, 82(5), 412-419.
224. Sawle, G. V., Hymas, N. F., Lees, A. J., & Frackowiak, R. S. (1991). Obsessional slowness: Functional studies with positron emission tomography. Brain, 114, 2191-2202.
225. Saxena, S., Brody, A. L., Ho, M. L., Alborzian, S., Maidment, K. M., Zohrabi, N., et al. (2002). Differential cerebral metabolic changes with paroxetine treatment of obsessive-compulsive disorder vs. major depression. Archives of General Psychiatry, 59(3), 250-261.
226. Saxena, S., Brody, A. L., Maidment, K. M., Smith, E. C., Zohrabi, N., Katz, E., et al. (2004, June). Cerebral glucose metabolism in obsessive-compulsive hoarding. American Journal of Psychiatry, 61(6), 6-1038.
227. Schaffer, H. R., & Emerson, P. E. (1964). The development of social attachments in infancy. Monographs for the Society for Research on Child Development, 29(3, Serial No. 94).
228. Schultz, R. T., Evans, D. W., & Wolfe, M. (1999). Neuropsychological models of childhood obsessive-compulsive disorder. Child and Adolescent Psychiatric Clinics of North America, 8, 513-531.
229. Schwartz, J. M., & Begley, S. (2002). The mind and the brain: Neuroplasticity and the power of mental force. New York: Regan Books.
230. Schwartz, J. M., Stoessel, P.W., Baxter, L. R., Jr., Martin, K. M., & Phelps, M. E. (1996). Systematic changes in cerebral glucose metabolic rate after successful behavior modification treatment of obsessive-compulsive disorder. Archives of General Psychiatry, 53, 109-113.
231. Senjo, M. (1989). Obsessive-compulsive disorder in people that abuse codeine. Acta Psychiatrcia Scandinavica, 79, 619-620.
232. Skoog, G., & Skoog, I. (1999). A 40-year follow-up of patients with obsessive-compulsive disorder. Archives of General Psychiatry, 56, 121-127.
233. Stein, D. J. (2000). Neurobiology of obsessive-compulsive spectrum disorders. Biological Psychiatry, 47, 296-304.
234. Steketee, G. S., Frost, R. O., Rheaume, J., & Wilheim, S. (1998). Cognitive theory and treatment of obsessive-compulsive disorder. In M. A. Jenike, L. Baer, & W. E. Minichiello (Eds.), Obsessive-compulsive disorders: Practical management (pp. 368-400). St. Louis, MO: Mosby.
235. Stevenson-Hinde, J. (1994). An ethological perspective. Psychological Inquiry, 5, 62-65.
236. Summerfeldt, L. J., Richter, M. A., Antony, M. M., & Swinson, R. P. (1999). Symptom structure in obsessive-compulsive disorder: A confirmatory factor-analytic study. Behavioral Research and Therapy, 37, 297-311.
237. Swedo, S. E., & Leonard, H. (1992). Trichotillomania: An obsessive compulsive spectrum disorder? Psychiatric Clinics of North America, 15, 777-790.
238. Swedo, S. E., Leonard, H. L., Garvey, M., Mittleman, B., Allen, A. J., Perlmutter, S., et al. (1998). Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections: Clinical description of the first 50 cases. American Journal of Psychiatry, 155(2), 264-271.
239. Swedo, S. E., Leonard, H. L., Kruesi, M. J. P., Rettew, D. C., Listwak, S. J., Berrettini, W., et al. (1992). Cerebrospinal f luid neurochemistry in children and adolescents with obsessive-compulsive disorder. Archives of General Psychiatry, 49, 29-36.
240. Swedo, S. E., Rapoport, J. L., Cheslow, D. L., Leonard, H. L., Ayoub, E. M., Hosier, D. M., et al. (1989). High prevalence of obsessivecompulsive symptoms in patients with Sydenham's chorea. American Journal of Psychiatry, 146(2), 246-249.
241. Tecott, L. (2003). The genes and brains of mice and men. American Journal of Psychiatry, 160(4), 646-656.
242. Tien, A. Y., Pearlson, G. D., Machlin, S. R., Bylsma, F. W., & Hoehn-Saric, R. (1992). Oculomotor performance in obsessive-compulsive disorder. American Journal of Psychiatry, 149, 641-646.
243. Valleni-Basile, L. A., Garrison, C. Z., Waller, J. L., Addy, C. L., McKeown, R. E., Jackson, K. L., et al. (1994). Frequency of obsessivecompulsive disorder in a community sample of young adolescents. Journal of the American Academy of Child and Adolescent Psychiatry, 33(6), 782-791.
244. van Balkom, A. J., van Oppen, P., Vermeulen, A. W. A., van Dyck, R., Nauta, M. C. E., & Vorst, H. C. M. (1994). A meta-analysis on the treatment of obsessive-compulsive disorder: A comparison of antidepressants, behavior therapy and cognitive therapy. Clinical Psychological Reviews, 14, 359-381.
245. van Oppen, P., De Haan, E., van Balkom, A. J., Spinhoven, P., Hoogduin, K., & van Dyck, R. (1995). Cognitive therapy and exposure in vivo in the treatment of obsessive-compulsive disorder. Behavioral Research and Therapy, 33, 379-390.
246. Waddington, C. H. (1977). Tools for thought. New York: Basic Books.
247. Werner, H. (1948). The comparative psychology of mental development. New York: International Universities Press.
248. Werner, H. (1957). The concept of development from a comparative and organismic point of view. In D. B. Harris (Ed.), The concept of development (pp. 125-146). Minneapolis: University of Minnesota Press.
249. Wewetzer, C., Jans, T., Muller, B., Neudorfl, A., Bucherl, U., Remschmidt, H., et al. (2001). Long-term outcome and prognosis of obsessive-compulsive disorder with onset in childhood or adolescence. European Child and Adolescent Psychiatry, 10(1), 37-46.
250. Willour, V. L., Yao Shugart, Y., Samuels, J., Grados, M., Cullen, B., Bienvenu, O. J., III, et al. (2004). Replication study supports evidence for linkage to 9p24 in obsessive-compulsive disorder. American Journal of Human Genetics, 75(3), 508-513.
251. Winnicott, D. W. (1958a). Primary maternal preoccupation. In Collected papers: Through paediatrics to psycho-analysis (pp. 300-305). New York: Basic Books. (Original work published 1956)
252. Winnicott, D. W. (1958b). Transitional objects and transitional phenomena. In Collected papers: Through paediatrics to psycho-analysis (pp. 229-242). New York: Basic Books. (Original work published 1951)
253. Yaryura-Tobias, J. A., Grunes, M. S., Todaro, J., McKay, D., Neziroglu, F. A., & Stockman, R. (2000). Nosological insertion of Axis I disorders in the etiology of obsessive-compulsive disorder. Journal of Anxiety Disorders, 14, 19-30.
254. Zelazo, P., & Jacques, S. (1996). Children's rule use: Representation, ref lection and cognitive control. In R. Vasta (Ed.), Annals of child development (Vol. 12, pp. 119-126). London: Jessica Kingsley Press.
255. Zelazo, P. D., & Reznick, J. S. (1991). Age-related asynchrony of knowledge and action. Child Development, 62(4), 719-735.
256. Zhang, H., Leckman, J. F., Tsai, C. P., Kidd, K. K., Rosario Campos, M. C., & Tourette Syndrome Association International Consortium for Genetics. (2002). Genome wide scan of hoarding in sibling pairs both diagnosed with Gilles de la Tourette syndrome. American Journal of Human Genetics, 70(4), 896-904.
257. Zhang, H., & Risch, N. (1996). Mapping quantitative-trait loci in humans by use of extreme concordant sib pairs: Selected sampling by parental phenotypes. American Journal of Human Genetics, 59, 951-957.
258. Zigler, E., & Glick, M. (1986). A developmental approach to adult psychopathology. New York: Wiley.
259. Zohar, A. H. (1999). The epidemiology of obsessive-compulsive disorder in children and adolescents. Child and Adolescent Psychiatric Clinics of North America, 8, 445-460.
260. Zohar, A. H., & Bruno, R. (1997). Normative and pathological obsessivecompulsive behavior and ideation in childhood: A question of timing. Journal of Child Psychology and Psychiatry and Allied Disciplines, 38(8), 993-999.
261. Zohar, A. H., & Felz, L. (2001). Ritualistic behavior in young children. Journal of Abnormal Child Psychology, 29(2), 121-128.
262. Zohar, A. H., LaBuda, M., & Moschel-Ravid, O. (1995). Obsessivecompulsive behaviors and cognitive functioning: A study of compulsivity, frame-shifting and Type A activity patterns in a normal population. Neuropsychiatry, Neuropsychology and Behavioral Neurology, 8, 163-167.
263. Zohar, A. H., Ratzoni, G., Pauls, D. L., Apter, A., Dycian, A., Binder, M., et al. (1992). An epidemiological study of obsessive-compulsive disorder and related disorders in Israeli adolescents. Journal of the American Academy of Child and Adolescent Psychiatry, 31(6), 1057-1061.
264. Zohar, J., & Insel, T. R. (1987). Obsessive-compulsive disorder: Psychobiological approaches to diagnosis, treatment, and pathophysiology. Biological Psychiatry, 2, 667-687.