Functional magnetic resonance imaging of symptom provocation in obsessive-compulsive disorder

Archives of General Psychiatry

Volumn 53, Issue 7, 1996, Pages 595-606

  Breiter, Hans C ^a   Rauch, Scott L ^a   Kwong, Kenneth K ^a   Baker, John R ^a   Weisskoff, Robert M ^a   Kennedy, David N ^a   Kendrick, Adair D ^a   Davis, Timothy L ^a   Jiang, Aiping ^a   Cohen, Mark S ^b   Stern, Chantal E ^a   Belliveau, John W ^a   Baer, Lee ^a   O'Sullivan, Richard L ^a   Savage, Cary R ^a   Jenike, Michael A ^a   Rosen, Bruce R ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BRAIN BLOOD FLOW; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; LIMBIC CORTEX; LIMBIC SYSTEM; NEUROANATOMY; NUCLEAR MAGNETIC RESONANCE IMAGING; OBSESSION; PROVOCATION;

EID: 8944255629     PISSN: 0003990X     EISSN: None     Source Type: Journal    
DOI: 10.1001/archpsyc.1996.01830070041008     Document Type: Article

References (70)

1. Baxter LR, Phelps ME, Maziotta JC, Guze BH, Schwarte JM, Selin SE. Local cerebral metabolic rates in obsessive-compulsive disorder. Arch Gen Psychiatry. 1987;44:211-218.
2. Baxter LR, Schwartz JM, Mazziotta JC, Phelps ME, Pahl JJ, Buze BE, Fair-banks L. Cerebral metabolic rates in non-depressed patients with obsessive-compulsive disorder. Am J Psychiatry. 1988;145:1560-1563.
3. Nordahl TE, Benkelfat C, Semple WE, Gross M, King AC, Cohen RM. Cerebral glucose metabolic rates in obsessive-compulsive disorder. Neuropsychopharmacology. 1989;2:23-28.
4. Swedo SE, Schapiro MB, Grady CL, Cheslow DL, Leonard HL, Kumar A, Friedland R, Rapoport SI, Rapoport JL. Cerebral glucose metabolism in childhood- onset obsessive-compulsive disorder. Arch Gen Psychiatry. 1989;46:518-523.
5. Benkelfat C, Nordahl TE, Semple WE, King AC, Murphy DL, Cohen RM. Local cerebral glucose metabolic rates in obsessive-compulsive disorder: patients treated with clomipramine. Arch Gen Psychiatry. 1990;47:840-848.
6. Martinot JL, Allilaire JF, Mazoyer BM, Hantouche E, Huret JD, Legaut-Demare F, Deslauriers AG, Hardy P, Pappata S, Baron JC, Syrota A. Obsessive-compulsive disorder: a clinical, neuropsychological and positron emission tomography study. Acta Psychiatr Scand. 1990;82:233-242.
7. Swedo SE, Pietrini P, Leonard HL, Schapiro MB, Rettew DC, Goldberger EL, Rapoport SI, Rapoport JL, Grady CL. Cerebral glucose metabolism in childhood-onset obsessive-compulsive disorder: revisualization during pharmacotherapy. Arch Gen Psychiatry. 1992;49:690-694.
8. Baxter LR, Schwartz JM, Bergman KS, Szuba MP, Guze BH, Mazziotta JC, Alazraki A, Selin CE, Ferng H-K, Munford P, Phelps ME. Caudate glucose metabolic rate changes with both drug and behavior therapy for obsessive-compulsive disorder. Arch Gen Psychiatry. 1992;49:681-689.
9. Baxter LR. Neuroimaging studies of obsessive-compulsive disorder. Psychiatr Clin North Am. 1992;15:871-884.
10. 2 and positron emission tomography. Arch Gen Psychiatry. 1994;51:62-70.
11. McGuire PK, Bench CJ, Frith CD, Marks IM, Frackowiak RS, Dolan RJ. Functional anatomy of obsessive-compulsive phenomena. Br J Psychiatry. 1994;164:459-468.
12. Machlin SR, Harris GJ, Pearlson GD, Hoehn-Saric R, Jeffery P, Camargo EE. Elevated medial-frontal cerebral blood flow in obsessive-compulsive patients: a SPECT study. Am J Psychiatry. 1991;148:1240-1242.
13. Rubin RT, Villanueva-Meyer J, Anath J, Trajmar PG, Mena I. Regional xenon 133 cerebral blood flow and cerebral technetium Tc 99m-HMPAO uptake in unmedicated patients with obsessive-compulsive disorder and matched normal control subjects: determination by high-resolution single-photon emission computed tomography. Arch Gen Psychiatry. 1992;49:695-702.
14. Zohar J, Insel TR, Berman KF, Foa EB, Hill JL, Weinberger DR. Anxiety and cerebral blood flow during behavioral challenge. Arch Gen Psychiatry. 1989;46:505-510.
15. Insel TR. Toward a neuroanatomy of obsessive-compulsive disorder. Arch Gen Psychiatry. 1992;49:739-744.
16. Rauch SL, Jenike MA. Neurobiological models of obsessive-compulsive disorder. Psychosomatics. 1993;34:20-32.
17. Belliveau JW, Kennedy DN, McKinstry RC, Buchbinder BR, Weisskoff RM, Cohen MS, Vevea JM, Brady TJ, Rosen BR. Functional mapping of the human visual cortex by magnetic resonance imaging. Science. 1991;254:716-719.
18. Brady TJ. Future prospects for MR imaging. Proc Soc Magn Reson Med. 1991;1:2.
19. Kwong KK, Belliveau JW, Chesler DA, Goldberg IE, Weisskoff RM, Poncelet BP, Kennedy DN, Hoppel BE, Cohen MS, Turner R, Cheng HM, Brady TJ, Rosen BR. Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation. Proc Natl Acad Sci U S A. 1992;89:5675-5679.
20. Ogawa S, Lee T, Nayak A, Glynn P. Oxygenation-sensitive contrast in magnetic resonance image of rodent brain at high magnetic fields. Magn Reson Med. 1990;14:68-78.
21. Ogawa S, Tank DW, Menon R, Ellermann JM, Kim SG, Merkle H, Ugurbil K. Intrinsic signal changes accompanying sensory stimulation: functional brain mapping using MRI. Proc Natl Acad Sci U S A. 1992;89:5951-5955.
22. McCarthy G, Blamire AM, Rothman DL, Gruetter R, Shulman RG. Echo-planar magnetic resonance imaging studies of frontal cortex activation during word generation in humans. Proc Natl Acad Sci U S A. 1993;90:4952-4956.
23. Cohen JD, Forman SD, Braver TS, Casey BJ, Servan-Schreiber D, Noll DC. Activation of the prefrontal cortex in a nonspatial working memory task with functional MRI. Hum Brain Mapping. 1994;1:293-304.
24. Bandettini PA, Jesmanowicz A, Wong EC, Hyde JS. Processing strategies for time-course data sets in functional MRI of the human brain. Magn Reson Med. 1993;30:161-173.
25. Menon RS, Ogawa S, Tank DW, Ugurbil K. 4 tesla gradient recalled echo characteristics of photic stimulation-induced signal changes in the human primary visual cortex. Magn Reson Med. 1993;30:380-386.
26. Rao SM, Binder JR, Bandettini PA, Hammeke TA, Yetkin FZ, Jesmanowica A, Lisk L, Morris GL, Mueller WM, Estowski LD, Wong EC, Haughton VM, Hyde JS. Functional magnetic resonance imaging of complex human movements. Neurology. 1993;43:2311-2318.
27. Kim S-G, Ashe J, Georgopoulos AP, Merkle H, Ellemann JM, Menon RS, Ogawa S, Ugurbil K. Functional imaging of the human motor cortex at high magnetic field. J Neurophysiol. 1993;69:297-302.
28. Binder JR, Rao SM, Hammeke TA, Yetkin FZ, Jesmanowicz A, Bandettini PA, Wong EC, Estkowski LD, Goldstein MD, Haughton VM, Hyde JS. Functional magnetic resonance imaging of human auditory cortex. Ann Neurol. 1994;35:662-672.
29. Breiter HC, Kwong KK, Baker JR, Belliveau JW, Davis TL, Baer L, O'Sullivan RM, Rauch SL, Savage CR, Cohen MS, Weisskoff RM, Brady TJ, Jenike MA, Rosen BR. Functional magnetic resonance imaging of symptom provocation in patients with obsessive compulsive disorder versus controls. Proc Soc Magn Reson Med. 1993;1:58. Abstract.
30. Pauling L, Coryell CD. The magnetic properties and structure of hemoglobin, oxyhemoglobin and carbonmonoxyhemoplobin. Proc Natl Acad Sci U S A. 1936;22:210.
31. Thulborn KR, Waterton JC, Matthew PM, Radda GK. Oxygenation dependence of the transverse relaxation time of water protons in whole blood at high field. Biochim Biophys Acta. 1982;714:265.
32. Bandettini PA, Wong EC, Hinks RS, Tikofsky RS, Hyde JS. Time course EPI of human brain function during task activation. Magn Reson Med. 1992;25:390-397.
33. Cohen MS, Weisskoff RM. Ultra-fast imaging. Magn Reson Imaging. 1991;9:1-37.
34. Blood AJ, Narayan SM, Toga AW. Stimulus parameters influence magnitude and time course of optical intrinsic responses in rodent barrel cortex. Proc Soc Heurosci. 1994;2:1422. Abstract.
35. Narayan SM, Blood AJ, Toga AW. Functional neural-vascular congruence over somatosensory cortex. Proc Soc Neurosci. 1994;2:1422. Abstract.
36. Cohen MS, Bookheimer S. Localization of brain function with magnetic resonance imaging. Trends Heurosci. 1994;17:268-277.
37. David A, Blamire A, Breiter H. Functional magnetic resonance imaging: a new technique with implications for psychology and psychiatry. Br J Psychiatry. 1994;164:2-7.
38. Rauch SL, Savage CR, Alpert NM, Miguel EC, Baer L, Breiter HC, Fischman AJ, Manzo PA, Moretti C, Jenike MA. A positron emission tomographic study of simple phobic symptom provocation. Arch Gen Psychiatry. 1995;52:20-28.
39. Goodman WK, Price LH, Rasmussen SA, Mazure C, Fleischmann RL, Hill CL, Heninger GR, Charney DS. The Yale-Brown Obsessive Compulsive Scale (YBOCS), I: development, use, and reliability. Arch Gen Psychiatry. 1989;46:1006-1011.
40. Goodman WK, Price LH, Rasmussen SA, Mazure C, Delgado P, Heninger GR, Charney DS. The Yale-Brown Obsessive Compulsive Scale (YBOCS), II: validity. Arch Gen Psychiatry. 1989;46:1012-1016.
41. Oldfield RC. The assessment and analysis of handedness: the Edinburgh inventory. Neuropsychologia. 1971;9:97-113.
42. Marks IM. Review of behavioral psychotherapy, I: obsessive-compulsive disorders. Am J Psychiatry. 1981;138:584-592.
43. Baer L. Getting Control: Overcoming Your Obsessions and Compulsions. Boston, Mass: Little Brown & Co; 1991:33-127.
44. Jiang A, Kennedy DN, Baker JR, Weisskoff RM, Tootell RBH, Woods RP, Benson RR, Kwong KK, Brady TJ, Rosen BR, Belliveau JW. Motion detection and correction in functional MR imaging. Hum Brain Mapping. 1995;3:1-12.
45. Woods RP, Cherry SR, Mazziotta JC. Rapid automated algorithm for aligning and reslicing PET images. J Comput Assist Tomogr. 1992;16:620-633.
46. Hajnal J, Myers R, Oatridge A, Schwieso J, Young I, Bydder G. Artifacts due to stimulus correlated motion in functional imaging of the brain. Magn Reson Med. 1994;31:283-291.
47. Fox PT, Mintun MA, Riemann EM, Raichle ME. Enhanced detection of focal brain responses using intersubject averaging and change-distribution analysis of subtracted PET images. J Cereb Blood Flow Metab. 1988;8:642-653.
48. Fristen KJ, Frith CD, Liddle P, Dolan RJ, Lamertsma AA, Frackowiak RJ. The relationship between global and local changes in PET scans. J Cereb Blood Flow Metab. 1990;10:458-466.
49. Fristen K, Frith C, Liddle P, Franckowiak R. Comparing functional PET images: the assessment of significant change. J Cereb Blood Flow Metab. 1991;11:690-699.
50. Worsley KJ, Evans AC, Marrett S, Neelin P. A three-dimensional statistical analysis for CBF activation studies in human brain. J Cereb Blood Flow Metab. 1992;12:900-918.
51. 15O tissue activity. J Nucl Med. 1989;30:141-149.
52. Baker JR, Hoppel BE, Stern CE, Kwong KK, Weisskoff RM, Rosen BR. Dynamic functional imaging of the complete human cortex using gradient echo and asymmetric spin-echo echo-planar magnetic resonance imaging. Proc Soc Magn Reson Med. 1993;3:1400. Abstract.
53. Press WH, Flannery BP, Teulolsky SA, Vetterling WT. Numerical Recipes: The Art of Scientific Computing. New York, NY: Cambridge University Press; 1986:472-475.
54. Davis TL, Weisskoff RM, Kwong KK, Boxerman JL, Rosen BR. Temporal aspects of fMRI task activation: dynamic modeling of oxygen delivery. Proc Soc Magn Reson Med. 1994;1:69.
55. Boxerman JL, Weisskoff RM, Kwong KK, Oavis TL, Rosen BR. The intravascular contribution to fMRI signal change: modeling and diffusion-weighted in vivo studies. Proc Soc Magn Reson Med. 1994;2:619.
56. Baker JR, Weisskoff RM, Stern CE, Kennedy DN, Jiang A, Kwong KK, Kolodny LB, Davis TL, Boxerman JL, Buchbinder BR, Wedeen VJ, Belliveau JW, Rosen BR. Statistical assessment of functional MRI signal change. Proc Soc Magn Reson Med. 1994;2:626.
57. Boxerman JL, Weisskoff RM, Rosen BR. The effects of water permeability, red blood cell velocity and agent compartmentalization on susceptibility-contrast relaxivity. Proc Soc Magn fleson Med. 1994;2:1008. Abstract.
58. Foreman SD, Cohen JD, Fitzgerald M, Eddy WF, Mintun MA, Noll DC. Improved assessment of significant activation in functional magnetic resonance imaging (fMRI): use of a cluster-size threshold. Magn Reson Med. 1995;33:636-647.
59. Rademacher J, Galaburda AM, Kennedy DN, Filipek PA, Caviness VS. Human cerebral cortex: localization, parcellation, and morphometry with magnetic resonance imaging. J Cogn Neurosci. 1992;4:352-373.
60. Filipek PA, Richelme C, Kennedy DN, Caviness VS. The young adult human brain: an MRI-based morphometric analysis. Cereb Cortex. 1994;4:344-360.
61. Talairach J, Tournoux P. Co-planar Stereotaxic Atlas of the Human Brain. New York, NY: Thieme Medical Publishers Inc; 1988.
62. Hoehn-Saric R, Pearlson GD, Harris GJ, Machlin SR, Camargo EE. Effects of fluoxetine on regional cerebral blood flow in obsessive-compulsive patients. Am J Psychiatry. 1991;148:1243-1245.
63. Mesulam M-M. Patterns in behavioral neuroanatomy: association areas, the limbic system, and hemispheric specialization. In: Mesulam M-M, ed. Principles of Behavioral Neurology. Philadelphia, Pa: FA Davis Co; 1985:1-70.
64. Kaada BR. Cingulate, posterior orbital, anterior insular and temporal pole cortex. In: Magoun HW, ed. Neurophysiology. Baltimore, Md: Waverly Press; 1960:1345-1372.
65. Kaada BR, Pribram KH, Epstein JA. Respiratory and vascular responses in monkeys from temporal pole, insula, orbital surface and circulate gyrus. J Neurophysiol. 1949;12:348-356.
66. Reiman EM, Lane RD, Ahern GL, Schwartz GE, Davidson RJ, Yun LS. Neuroanatomical correlates of normal human emotion. Proc Soc Neurosci. 1993;19:371. Abstract.
67. Pardo JV, Pardo PJ, Raichle ME. Neural correlates of self-dysphoria. Am J Psychiatry. 1993;150:713-719.
68. George MS, Ketter TA, Parekh PI, Horwitz B, Herscovitch P, Post RM. Brain activity during transient sadness and happiness in healthy women. Am J Psychiatry. 1995;152:341-351.
69. LeDoux JE. Emotion and the amygdala. In: Aggleton JP, ed. The Amygdala: Neurobiological Aspects of Emotion, Memory, and Mental Dysfunction. New York, NY: Wiley-Liss Inc; 1992:339-351.
70. Baer L, Jenike MA. Introduction. In: Jenike MA, Bear L, Minichiello WE, eds. Obsessive-compulsive Disorders: Theory and Management. 2nd ed. Chicago, III: Year Book Medical Publishers; 1990:3-9.