Genome-wide linkage analysis of families with obsessive-compulsive disorder ascertained through pediatric probands

American Journal of Medical Genetics - Neuropsychiatric Genetics

Volumn 114, Issue 5, 2002, Pages 541-552

  Hanna, Gregory L ^a,c   Veenstra VanderWeele, Jeremy ^b   Cox, Nancy J ^b   Boehnke, Michael ^c   Himle, Joseph A ^a   Curtis, George C ^a   Leventhal, Bennett L ^b   Cook Jr , Edwin H ^b  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Genome scan; Linkage analysis; Microsatellite markers; Obsessive compulsive disorder; Susceptibility loci; Tourette disorder

Indexed keywords

ADOLESCENT; ARTICLE; CHILD; CHROMOSOME 16; CHROMOSOME 2; CHROMOSOME 9; CHROMOSOME MAP; CLINICAL ARTICLE; COMPULSION; FAMILY STUDY; FEMALE; GENETIC ANALYSIS; GENETIC LINKAGE; GENOME; GENOTYPE; GILLES DE LA TOURETTE SYNDROME; HUMAN; MALE; MICROSATELLITE MARKER; OBSESSION; PRIORITY JOURNAL; TIC;

ADOLESCENT; CHILD; CHROMOSOME MAPPING; FAMILY HEALTH; FEMALE; GENOME, HUMAN; GENOTYPE; HUMANS; INTERVIEWS; LINKAGE (GENETICS); LOD SCORE; MALE; MICROSATELLITE REPEATS; OBSESSIVE-COMPULSIVE DISORDER; PEDIGREE; PENETRANCE;

EID: 0037043047     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/ajmg.10519     Document Type: Article

References (79)

1. Segregation analysis of obsessive-compulsive disorder using symptombased factor scores
2. The genetics of six neurotic disorders: A twin study
3. Evidence for a general neurotic syndrome
4. The genetics of Hashimoto's disease
5. Genome scan for linkage to Gilles de la Tourette syndrome
6. Association of the serotonin transporter promoter regulatory region polymorphism and obsessive-compulsive disorder
7. Autism, affective and other psychiatric disorders: Patterns of familial aggregation
8. Age at onset of selected mental disorders in five community populations
9. Twin and family studies of anxiety, phobic and obsessive disorders
10. Complex segregation analysis for obsessive compulsive disorder and related disorders
11. Effects of misspecifying genetic parameters in lod score analysis
12. Genetic and environmental influences on obsessional traits and symptoms
13. Obsessive-compulsive disorder in a birth cohort of 18-year-olds: Prevalence and predictors
14. Obsessive compulsive disorder in adolescence: An epidemiological study
15. Genetics of Type 1 diabetes mellitus
16. Is juvenile obsessive-compulsive disorder a developmental subtype of the disorder? A review of the pediatric literature
17. Familial aggregation and phenomenology of 'early'-onset (at or before age 20 years) panic disorder
18. The Yale-Brown Obsessive Compulsive Scale: I. Development, use, and reliability
19. Yale-Brown Obsessive Compulsive Scale: II. Validity
20. The genetics of Graves' disease
21. The power to detect linkage in complex disease by means of simple LOD-score analyses
22. Linkage of early-onset familial breast cancer to chromosome 17q21
23. Demographic and clinical features of obsessive-compulsive disorder in children and adolescents
24. Prolactin in childhood obsessive-compulsive disorder: Clinical correlates and response to clomipramine
25. Serotonin transporter and seasonal variation in blood serotonin in families with obsessive-compulsive disorder
26. A review and meta-analysis of the genetic epidemiology of anxiety disorders
27. Sensitivity of lod scores to changes in diagnostic status
28. Similar and dissimilar manifestations of obsessive-compulsive neurosis in monozygotic twins
29. The epidemiology of obsessive-compulsive disorder in five US communities
30. Mutation screening of human 5-HT2B receptor gene in early-onset obsessive-compulsive disorder
31. Test-retest reliability of team consensus best-estimate diagnoses of axis I and II disorders in a family study
32. Allele-sharing models: LOD scores and accurate linkage tests
33. Parametric and nonparametric linkage analysis: A unified multipoint approach
34. Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results
35. Genetic dissection of complex traits
36. Obsessive-compulsive disorder in childhood
37. Best estimate of lifetime psychiatric diagnosis: A methodological study
38. Tic-related vs. non-tic-related obsessive-compulsive disorder
39. Psychiatric disorders in first degree relatives of children and adolescents with obsessive compulsive disorder
40. Tics and Tourette's disorder: A 2- to 7-year follow-up of 54 obsessive-compulsive children
41. Genetic susceptibility to the connective tissue diseases
42. Haloperidol addition in fluvoxamine-refractory obsessive-compulsive disorder: A double blind placebo-controlled study in patients with and without tics
43. Evidence for linkage disequilibrium between serotonin transporter protein gene (SLCD6A4) and obsessive compulsive disorder
44. Significant linkage for Tourette syndrome in a large French Canadian family
45. A family study of obsessive-compulsive disorder
46. Complex segregation analysis provides compelling evidence for a major gene underlying obsessive-compulsive disorder and for heterogeneity by sex
47. Segregation analysis of obsessive compulsive and associated disorders: Preliminary results
48. Gender-divergent aetiological factors in obsessive-compulsive disorder
49. Linkage analysis with misclassification at one locus
50. The inheritance of Gilles de la Tourette's syndrome and associated behaviors
51. Gilles de la Tourette's syndrome and obsessive-compulsive disorder: Evidence supporting a genetic relationship
52. A family study of Gilles de la Tourette syndrome
53. Risks of affective illness among first-degree relatives of bipolar I old-order Amish probands
54. A family study of obsessive-compulsive disorder
55. A twin study of Tourette's syndrome
56. Schizophrenia: Age at onset, gender and familial risk
57. Prevalence of psychiatric disorders in a community population of older adolescents
58. Identification of genetic markers associated with Gilles de la Tourette syndrome in an Afrikaner population
59. The Structured Clinical Interview for DSM-III-R (SCID). I: History, rationale, and description
60. Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections: Clinical description of the first 50 cases
61. 9p monosomy in a patient with Gilles de la Tourette's syndrome
62. Obsessive-compulsive disorder in children and adolescents. Self-reported obsessive-compulsive behaviour in pupils in Denmark
63. Genetic factors in anxiety disorders
64. A complete genome screen in sib pairs affected by Gilles de la Tourette syndrome
65. Frequency of obsessive-compulsive disorder in a community sample of young adolescents
66. Mapping of a gene predisposing to early-onset Alzheimer's disease to chromosome 14q24.3
67. Coupling of optimized multiplex PCR and automated capillary electrophoresis for efficient genome-wide searches
68. Genomic organization of the SLC1A1/EAAC1 gene and mutation screening in early-onset obsessive-compulsive disorder
69. Earlyonset major depression in parents and their children
70. The cross national epidemiology of obsessive compulsive disorder
71. The Structured Clinical Interview for DSM-III-R (SCID). II. Multisite test-retest reliability
72. An epidemiological study of obsessive-compulsive disorder and related disorders in Israeli adolescents