Replication study supports evidence for linkage to 9p24 in obsessive-compulsive disorder

American Journal of Human Genetics

Volumn 75, Issue 3, 2004, Pages 508-513

  Willour, Virginia L ^a,d   Shugart, Yin Yao ^b   Samuels, Jack ^a,b   Grados, Marco ^a,c   Cullen, Bernadette ^a   Bienvenu III, O Joseph ^a   Wang, Ying ^a   Liang, Kung Yee ^b   Valle, David ^a   Hoehn Saric, Rudolf ^a   Riddle, Mark ^a   Nestadt, Gerald ^a,b  

^a Institute for Cell Engineering   (United States)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^c KENNEDY KRIEGER INSTITUTE   (United States)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CHROMOSOME 9P; GENETIC LINKAGE; HUMAN; MAJOR CLINICAL STUDY; MARKER GENE; MICROSATELLITE MARKER; OBSESSIVE COMPULSIVE DISORDER; PRIORITY JOURNAL;

EID: 4143118848     PISSN: 00029297     EISSN: None     Source Type: Journal    
DOI: 10.1086/423899     Document Type: Article

References (24)

1. American Psychiatric Association (1994) Diagnostic and Statistical Manual of Mental Disorders. 4th ed. American Psychiatric Association, Washington, DC
2. Broman KW, Murray JC, Sheffield VC, White RL, Weber JL (1998) Comprehensive human genetic maps: individual and sex-specific variation in recombination. Am J Hum Genet 63:861-869
3. Cooper J (1970) The Leyton Obsessional Inventory. Psychol Med 1:48-64
4. Goodman WK, Price LH, Rasmussen SA, Mazure C, Fleischmann RL, Hill CL, Heninger GR, Charney DS (1989) The Yale-Brown Obsessive Compulsive Scale. 1. Development, use, and reliability. Arch Gen Psychiatry 46:1006-1011
5. Grados MA, Walkup J, Walford S (2003) Genetics of obsessive-compulsive disorders: new findings and challenges. Brain Dev Suppl 25:S55-S61
6. Hanna GL, Veenstra-VanderWeele J, Cox NJ, Boehnke M, Himle JA, Curtis GC, Leventhal BL, Cook EH Jr (2002) Genome-wide linkage analysis of families with obsessive-compulsive disorder ascertained through pediatric probands. Am J Med Genet 114:541-552
7. International HapMap Consortium (2003) The International HapMap Project. Nature 426:789-796
8. Kent WJ, Sugnet CW, Furey TS, Roskin KM, Pringle TH, Zahler AM, Haussler D (2002) The human genome browser at UCSC. Genome Res 12:996-1006
9. Kong A, Gudbjartsson DF, Sainz J, Jonsdotlir GM, Gudjonsson SA, Richardsson B, Sigurdardottir S, Barnard J, Hallbeck B, Masson G, Shlien A, Palsson ST, Frigge ML, Thorgeirsson TE, Gulcher JR, Stefansson K (2002) A high-resolution recombination map of the human genome. Nat Genet 31:241-247
10. Kruglyak L, Daly MJ, Reeve-Daly MP, Lander ES (1996) Parametric and nonparametric linkage analysis: a unified multipoint approach. Am J Hum Genet 58:1347-1363
11. Lander E, Kruglyak L (1995) Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat Genet 11:241-247
12. Lathrop GM, Lalouel JM (1984) Easy calculations of LOD scores and genetic risks on small computers. Am J Hum Genet 36:460-465
13. Mannuzza S, Fyer AJ, Endicott J, Klein DF (1985) Family Informant Schedule and Criteria. Anxiety Family Study Unit, New York State Psychiatric Institute, New York
14. Mannuzza S, Fyer AJ, Klein DF, Endicott J (1986) Schedule for Affective Disorders and Schizophrenia-Lifetime Version modified for the study of anxiety disorders (SADS-LA): rationale and conceptual development. J Psychiatr Res 20:317-325
15. Martin ER, Monks SA, Warren LL, Kaplan NL (2000) A test for linkage and association in general pedigrees: the pedigree disequilibrium test. Am J Hum Genet 67:146-154
16. McPeek MS, Sun L (2000) Statistical tests for detection of misspecified relationships by use of genome-screen data. Am J Hum Genet 66:1076-1094
17. Murray CL, Lopez AD (1996) The global burden of disease: a comprehensive assessment of mortality and disability from diseases, injuries, and risk factors in 1990 and projected. Harvard University Press, Cambridge, MA
18. Nestadt G, Samuels J, Riddle M, Bienvenu OJ III, Liang KY, LaBuda M, Walkup J, Grados M, Hoehn-Saric R (2000) A family study of obsessive-compulsive disorder. Arch Gen Psychiatry 57:358-363
19. O'Connell JR, Weeks DE (1998) PedCheck: a program for identification of genotype incompatibilities in linkage analysis. Am J Hum Genet 63:259-266
20. Pato MT, Schindler KM, Pato CN (2001) The genetics of obsessive-compulsive disorder. Curr Psychiatry Rep 3:163-168
21. Roberts SB, MacLean CJ, Neale MC, Eaves LJ, Kendler KS (1999) Replication of linkage studies of complex traits: an examination of variation in location estimates. Am J Hum Genet 65:876-884
22. Samuels J, Nestadt G (1997) Epidemiology and genetics of obsessive-compulsive disorder. Int Rev Psychiatry 9:61-71
23. Veenstra-VanderWeele J, Kim SJ, Gonen D, Hanna GL, Leventhal BL, Cook EH Jr (2001) Genomic organization of the SLC1A1/EAAC1 gene and mutation screening in early-onset obsessive-compulsive disorder. Mol Psychiatry 6:160-167
24. Wheeler DL, Church DM, Edgar R, Federhen S, Helmberg W, Madden TL, Pontius JU, Schuler GD, Schriml LM, Sequeira E, Suzek TO, Tatusova TA, Wagner L (2004) Database resources of the National Center for Biotechnology Information: update. Nucleic Acids Res 32:D35-D40