Neurobiology of the obsessive-compulsive spectrum disorders

Biological Psychiatry

Volumn 47, Issue 4, 2000, Pages 296-304

  Stein, Dan J ^a,b  

^a STELLENBOSCH UNIVERSITY   (South Africa)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

Obsessive compulsive disorder; Obsessive compulsive spectrum

Indexed keywords

COMPULSION; HUMAN; IMPULSIVENESS; MENTAL DISEASE; NEUROANATOMY; NEUROBIOLOGY; NEUROCHEMISTRY; NEUROIMMUNOLOGY; NEUROSIS; NONHUMAN; OBSESSION; PERSONALITY DISORDER; PRIORITY JOURNAL; REVIEW; STEREOTYPY;

BRAIN; HUMANS; NEUROTRANSMITTER AGENTS; OBSESSIVE-COMPULSIVE DISORDER;

EID: 0033957052     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3223(99)00271-1     Document Type: Review

References (78)

1. Altemus M., Pigott T., Kalogeras K.T., et al. Abnormalities in the regulation of vasopressin and corticotropin releasing factor secretion in obsessive-compulsive disorder. Arch Gen Psychiatry. 49:1992;9-20.
2. Baer L. Factor analysis of symptom subtypes of obsessive-compulsive disorder and their relation to personality and tic disorders. J Clin Psychiatry. 55S:1994;18-23.
3. Barr L.C., Goodman W.C., Price L.H., et al. The serotonin hypothesis of obsessive compulsive disorder Implications of pharmacologic challenge studies . J Clin Psychiatry. 53S:1992;17-28.
4. Baxter L.R., Saxena S., Brody A.L., et al. Brain mediation of obsessive-compulsive disorder symptoms Evidence from functional brain imaging studies in the human and nonhuman primate . Sem Clin Neuropsychiatry. 1:1996;32-47.
5. Baxter L.R., Schwartz J.M., Bergman K.S., et al. Caudate glucose metabolic rate changes with both drug and behavior therapy for OCD. Arch Gen Psychiatry. 49:1992;681-689.
6. Bergh C., Eklund T., Sodersten P., et al. Altered dopamine function in pathological gambling. Psychol Med. 27:1997;473-475.
7. Black D.W., Goldstein R.B., Noyes R. Jr, et al. Compulsive behaviors and obsessive-compulsive disorder (OCD) Lack of a relationship between OCD, eating disorders, and gambling . Compr Psychiatry. 35:1994;145-148.
8. 2 receptor gene variants Association and linkage studies in impulsive-addictive-compulsive behaviour . Pharmacogenetics. 5:1995;121-141.
9. Braun A.R., Randolph C., Stoetter B., et al. The functional neuroanatomy of Tourette's syndrome an FDG-PET study. II. Relationships between regional cerebral metabolism and associated behavioral and cognitive features of the illness . Neuropsychopharmacology. 13:1995;151-168.
10. Castellanos F.X., Ritchie F.G., Marsh W.L., et al. DSM-IV stereotypic movement disorder Persistence of stereotypies of infancy in intellectually normal adolescents and adults . J Clin Psychiatry. 57:1996;116-122.
11. Cheyette S.R., Cummings J.L. Encephalitis lethargica Lessons for contemporary neuropsychiatry . J Neuropsychiatry Clin Neurosci. 7:1995;125-134.
12. Comings D.E., Wu S., Chiu C., et al. Polygenic inheritance of Tourette syndrome, stuttering, attention deficit hyperactivity, conduct, and oppositional defiant disorder The additive and subtractive effect of the three dopaminergic genes - DRD2, DBH and DAT1 . Am J Med Genet. 67:1996;264-288.
13. Cummings J.L. Frontal-subcortical circuits and human behavior. Arch Neurol. 50:1993;873-880.
14. Davidson J.R.T., Boyko O., Charles H.C., et al. Magnetic resonance spectroscopy in social phobia. J Clin Psychiatry. 54:1993;S19-S25.
15. Dodman NH, Moon-Fanelli A, Mertens PA, et al (1997): Animal models of obsessive-compulsive disorder. In: Hollander E, Stein DJ, editors. Obsessive-Compulsive Disorders: Diagnosis, Etiology, Treatment. New York: Marcel Dekker, 99-144.
16. Enright S.J., Beech A.R. Reduced cognitive inhibition in obsessive-compulsive disorder. Br J Clin Psychol. 32:1993;67-74.
17. Eriksson E., Hedberg M.A., Andersch B., et al. The serotonin reuptake inhibitor paroxetine is superior to the noradrenaline reuptake inhibitor maprotiline in the treatment of premenstrual syndrome. Neuropsychopharmacology. 12:1995;167-176.
18. Goodman W.K., McDougle C.J., Price L.H., et al. Beyond the serotonin hypothesis A role for dopamine in some forms of obsessive compulsive disorder? J Clin Psychiatry. 51:1990;S36-S43.
19. Gordon C.T., Rapoport J.L., Hamburger S.D., et al. Differential response of seven subjects with autistic disorder to clomipramine and desipramine. Am J Psychiatry. 149:1992;363-366.
20. Hawkridge S., Stein D.J., Bouwer C. Combining neuroleptics with serotonin specific reuptake inhibitors in Tourette's syndrome. J Am Acad Child Adolesc Psychiatry. 35:1996;703-704.
21. Hollander E. Obsessive-Compulsive Related Disorders. 1993;American Psychiatric Press, Washington, DC.
22. Hollander E., DelGiudice-Asch G., Simon L., et al. B lymphocyte antigen D8/17 and repetitive behaviors in autism. Am J Psychiatry. 156:1999;317-320.
23. Hyde T.M., Weinberger D.R. Tourette's syndrome A model neuropsychiatric disorder . JAMA. 273:1995;498-501.
24. Insel T.R. Toward a neuroanatomy of obsessive-compulsive disorder. Arch Gen Psychiatry. 49:1992;739-744.
25. Jenike M.A. Obsessive-compulsive and related disorders A hidden epidemic . N Engl J Med. 321:1989;539-541.
26. Jenike M.A., Brotman A.W. The EEG in obsessive-compulsive disorder. J Clin Psychiatry. 45:1984;122-124.
27. Kapur S., Remington G. Serotonin-dopamine interaction and its relevance to schizophrenia. Am J Psychiatry. 153:1996;466-476.
28. Karayiorgou M., Altemus M., Galke B.L., et al. Genotype determining low catechol-O-methyltransferase activity as a risk factor for obsessive-compulsive disorder. Proc Natl Acad Sci U S A. 94:1997;4572-4575.
29. Klein D.F. Forward. Hollander E. Obsessive-Compulsive Related Disorders. 1993;American Psychiatric Press, Washington, DC.
30. Kruesi M.J.P., Fine S., Valladares L., et al. Paraphilias A double-blind crossover comparison of clomipramine versus desipramine . Arch Sex Behav. 21:1992;587-593.
31. Leckman J.F. What genes confer vulnerability to Gilles de la Tourette's syndrome? Psychiatr Ann. 27:1997;293-296.
32. Leckman J.F., Goodman W.K., North W.G., et al. The role of central oxytocin in obsessive compulsive disorder and related normal behavior. Psychoneuroendocrinology. 19:1994;723-749.
33. Lenane M.C., Swedo S.E., Rapoport J.L., et al. Rates of obsessive-compulsive disorder in first-degree relatives of patients with trichotillomania A research note . J Child Psychol Psychiatry. 33:1992;925-933.
34. Leonard H.L., Lenane M.C., Swedo S.E., et al. A double-blind comparison of clomipramine and desipramine treatment of severe onychophagia (nail biting). Arch Gen Psychiatry. 48:1991;821-827.
35. Lucey J.V., Costa D.C., Busatto G., et al. Caudate regional cerebral blood flow in obsessive-compulsive disorder, panic disorder and healthy controls on single photon emission computerized tomography. Psychiatry Res. 74:1997;25-33.
36. Malison R.T., McDougle C.J., van Dyck C.H., et al. [123I]B-CIT SPECT imaging of striatal dopamine transporter binding in Tourette's disorder. Am J Psychiatry. 152:1995;1359-1361.
37. Martin A., Scahill L., Vitulano L., et al. Stimulant use and trichotillomania [letter]. J Am Acad Child Adolesc Psychiatry. 37:1998;349-350.
38. Martin L.J., Spicer D.M., Lewis M.H., et al. Social deprivation of infant monkeys alters the chemoarchitecture of the brain I. Subcortical regions . J Neurosci. 11:1991;3344-3358.
39. McDougle C.J., Goodman W.K., Leckman J.F., et al. Haloperidol addition in fluvoxamine-refractory obsessive-compulsive disorder A double-blind placebo-controlled study in patients with and without tics . Arch Gen Psychiatry. 51:1994;302-308.
40. McElroy S.L., Phillips K.A., Keck P.E. Jr. Obsessive-compulsive spectrum disorders. J Clin Psychiatry. 55:1994;33-51.
41. Mikkelsen E.J., Albert L.G., Emens M., et al. The efficacy of antidepressant medication for individuals with mental retardation. Psychiatr Annals. 27:1997;198-206.
42. Mittleman B.B., Castellanos F.X., Jacobsen L.K., et al. Cerebrospinal fluid cytokines in pediatric neuropsychiatric disease. J Immunol. 159:1997;2994-2999.
43. Moriarty J., Eapen V., Costa D.C., et al. HMPAO SPET does not distinguish obsessive-compulsive and tic syndromes in families multiply affected with Gilles de la Tourette's syndrome. Psychol Med. 27:1997;737-740.
44. Murphy TK, Goodman WK, Fudge MW, et al (1997): B Lymphoctye antigen D8/17: A peripheral marker for childhood-onset obsessive-compulsive disorder and Tourette's syndrome? Am J Psychiatry 1997;154:402-407.
45. Nicolini H., Cruz C., Paez F., et al. Dopamine D2 and D4 receptor genes distinguish the clinical presence of tics in obsessive-compulsive disorder. Gac Med Mex. 134:1998;521-572.
46. Niehaus D.J.H., Knowles J.A., van Kradenberg J., et al. D8/17 in obsessive-compulsive disorder and trichotillomania (let.). S Afr Med J. 89:1999;755-756.
47. O'Sullivan R.L., Rauch S.L., Breiter H.C., et al. Reduced basal ganglia volumes in trichotillomania measured via morphometric MRI. Biol Psychiatry. 42:1997;39-45.
48. Palumbo D., Maugham A., Kurlan R. Hypothesis III Tourette syndrome is only one of several causes of a developmental basal ganglia syndrome . Arch Gen Psychiatry. 54:1997;475-483.
49. Pauls D.L., Towbin K.E., Leckman J.F., et al. Gilles de la Tourette's syndrome and obsessive-compulsive disorder Evidence supporting a genetic relationship . Arch Gen Psychiatry. 43:1986;1180-1182.
50. Phillips K.A., McElroy S.L., Keck P.E. Jr, et al. Body dysmorphic disorder 30 cases of imagined ugliness . Am J Psychiatry. 150:1993;302-308.
51. Potts N.L., Davidson J.R., Krishman K.R., et al. Magnetic resonance imaging in patients with social phobia. Psychiatry Res. 52:1994;35-42.
52. Rapoport J.L., Ryland D.H., Kriete M. Drug treatment of canine acral lick An animal model of obsessive-compulsive disorder . Arch Gen Psychiatry. 48:1992;517-521.
53. Rasmussen S.A. Obsessive compulsive spectrum disorders. J Clin Psychiatry. 55:1994;89-91.
54. Rasmusson A.M., Anderson G.M., Lynch K.A., et al. A preliminary study of tryptophan depletion on tics, obsessive-compulsive symptoms, and mood in Tourette's syndrome. Biol Psychiatry. 41:1997;117-121.
55. Rauch SL, Savage CR (1997): Neuroimaging and neuropsychology of the striatum. Psychiatr Clin North Am 20:741-768.
56. Rauch S.L., Savage C.R., Alpert N.M., et al. The functional neuroanatomy of anxiety A study of three disorders using positron emission tomography and symptom provocation . Biol Psychiatry. 42:1997;446-452.
57. Ridley R.M. The psychology of perseverative and stereotyped behavior. Prog Neurobiol. 44:1994;221-231.
58. Scahill L., Riddle M.A., King R.A., et al. Fluoxetine has no marked effect on tic symptoms in patients with Tourette's syndrome A double-blind placebo-controlled study . J Child Adolesc Psychopharmacol. 7:1997;75-85.
59. Singer H.S., Hahn I.H., Moran T.H. Abnormal dopamine uptake sites in postmortem striatum from patients with Tourette's syndrome. Ann Neurol. 30:1991;558-562.
60. Singer H.S., Reiss A.L., Brown J.E., Aylward E.H., Shih B., Chee E., et al. Volumetric changes in basal ganglia of children with Tourette's syndrome. Neurology. 43:1993;950-956.
61. Stein D.J., Bouwer C. A neuro-evolutionary approach to the anxiety disorders. J Anxiety Dis. 11:1997;409-429.
62. Stein D.J., Bouwer C., Hawkridge S., et al. Risperidone augmentation of serotonin reuptake inhibitors in obsessive-compulsive and related disorders. J Clin Psychiatry. 58:1997;119-122.
63. Stein D.J., Coetzer R., Lee M., et al. Magnetic resonance brain imaging in women with obsessive-compulsive disorder and trichotillomania. Psychiatry Res. 74:1997;177-182.
64. Stein D.J., Hollander E. Low-dose pimozide augmentation of serotonin reuptake blockers in the treatment of trichotillomania. J Clin Psychiatry. 53:1992;123-126.
65. Stein D.J., Hollander E. The spectrum of obsessive-compulsive related disorders. Hollander E. Obsessive-Compulsive Related Disorders. 1993;American Psychiatric Press, Washington, DC.
66. Stein D.J., Hollander E. Impulsive aggression and obsessive-compulsive disorder. Psychiatr Annals. 23:1993;389-395.
67. Stein D.J., Hollander E., Anthony D., Schneier F.R., Fallon B.A., Liebowitz M.R., Klein D.F. Serotonergic medications for sexual obsessions, sexual addictions, and paraphilias. J Clin Psychiatry. 53:1992;267-271.
68. Stein D.J., Simeon D., Cohen L., et al. Trichotillomania and obsessive-compulsive disorder. J Clin Psychiatry. 4:1995;28-34.
69. Stein D.J., Wessels C., Carr J., et al. Hair-pulling in a patient with Sydenham's chorea. Am J Psychiatry. 154:1997;1320.
70. Swedo S.E., Leonard H.L., Garvey M., et al. Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections Clinical description of the first 50 cases . Am J Psychiatry. 155:1998;264-271.
71. Swedo S.E., Leonard H.L., Lenane M.C., et al. Trichotillomania A profile of the disorder from infancy through adulthood . Int Pediatrics. 7:1992;144-150.
72. Swedo S.E., Leonard H.L., Rapoport J.L., et al. A double-blind comparison of clomipramine and desipramine in the treatment of trichotillomania (hair pulling). N Engl J Med. 321:1989;497-501.
73. Swedo S.E., Rapoport J.L., Leonard H.L., et al. Regional cerebral glucose metabolism of women with trichotillomania. Arch Gen Psychiatry. 48:1991;828-833.
74. Thoren P., Asberg M., Bertilsson L., et al. Clomipramine treatment of obsessive-compulsive disorder. II. Biochemical aspects. Arch Gen Psychiatry. 37:1980;1289-1294.
75. Yaryura-Tobias J.A., Neziroglu F.A. Obsessive-Compulsive Disorder Spectrum. 1997;American Psychiatric Press, Washington, DC.
76. van Amerigen M, Mancini C (1996, March): Treatment of trichotillomania with haloperidol. Paper presented at the annual meeting of the Anxiety Disorders Association of America, Orlando, FL.
77. Wolf S.S., Jones D.W., Knable M.B., et al. Tourette syndrome Prediction of phenotypic variation in monozygotic twins by caudate nucleus D2 receptor binding . Science. 273:1996;1225-1227.
78. Zohar J., Insel T.R. Obsessive-compulsive disorder Psychobiological approaches to diagnosis, treatment, and pathophysiology . Biol Psychiatry. 22:1987;667-687.