Mapping quantitative-trait loci in humans by use of extreme concordant sib pairs: Selected sampling by parental phenotypes

American Journal of Human Genetics

Volumn 59, Issue 4, 1996, Pages 951-957

  Zhang, Heping ^a   Risch, Neil ^b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CALCULATION; GENE FREQUENCY; GENE MAPPING; GENETIC MODEL; MATHEMATICAL MODEL; PARENT; PHENOTYPE; PRIORITY JOURNAL; QUANTITATIVE TRAIT; SIBLING;

CHROMOSOME MAPPING; FEMALE; GENOTYPE; HUMANS; LINKAGE (GENETICS); MALE; MODELS, GENETIC; PHENOTYPE; PROBABILITY;

EID: 0029794185     PISSN: 00029297     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. Eaves L, Meyer J (1994) Locating human quantitative trait loci: guidelines for the selection of sibling pairs for genotyping. Behav Genet 24:443-455
2. Nielsen KL (1964) Methods in numerical analysis, 2d ed. Macmillan, New York
3. Risch N, Zhang H (1995) Extreme discordant sib pairs for mapping quantitative trait loci in humans. Science 268:1584-1589
4. _ (1996) Mapping quantitative trait loci with extreme discordant sib pairs: sample size considerations. Am J Hum Genet 58:836-843
5. Steck GP (1958) A table for computing trivariate normal probabilities. Ann Math Stat 29:780-800